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Angiogenesi

Angiogenesi

Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.

Sottocategorie di "Angiogenesi"

Mostrare 6 più sottocategorie

Trovati 2121 prodotti di "Angiogenesi"

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  • Sitravatinib malate
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    Sitravatinib malate

    CAS:
    <p>Sitravatinib malate is an orally bioavailable receptor inhibitor of tyrosine kinase (RTK) (IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5</p>
    Formula:C37H35F2N5O9S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:763.76

    Ref: TM-T12925

  • VEGFR-2-IN-27
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    VEGFR-2-IN-27

    CAS:
    VEGFR-2-IN-27 (compound 7a) is a potent inhibitor of VEGFR-2 (IC50: 14.8 nM) and can be used in anticancer studies.
    Formula:C25H21FN4O4
    Colore e forma:Solid
    Peso molecolare:460.46

    Ref: TM-T62901

  • Lck Inhibitor III
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    Lck Inhibitor III

    CAS:
    Lck Inhibitor III, a potent inhibitor of Lck, exhibits an IC50 value of 867 nM.
    Formula:C25H30N6O4
    Colore e forma:Solid
    Peso molecolare:478.54

    Ref: TM-T72586

  • Gefitinib N-oxide
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    Gefitinib N-oxide

    CAS:
    Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib N-oxide is the N-oxide derivative of Gefitinib.
    Formula:C22H24ClFN4O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:462.9

    Ref: TM-T11385

  • CP-547632 hydrochloride
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    CP-547632 hydrochloride

    CAS:
    CP-547632 hydrochloride: oral VEGFR-2/FGF inhibitor (IC50: 11/9 nM), well-tolerated, antitumor.
    Formula:C20H25BrClF2N5O3S
    Colore e forma:Solid
    Peso molecolare:568.86

    Ref: TM-T10870

  • EMI48
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    EMI48

    CAS:
    EMI48, a derivative of EMI1, exhibits increased efficacy against mutant EGFR compared to EMI1. It specifically inhibits EGFR triple mutants [1].
    Formula:C21H20N2O3
    Colore e forma:Solid
    Peso molecolare:348.4

    Ref: TM-T61179

  • EGFR-IN-39
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    EGFR-IN-39

    CAS:
    EGFR-IN-39, an acrylamide, is a potent EGFR inhibitor and antitumor agent targeting NSCLC with low toxicity. See WO2021185348A1 for details.
    Formula:C24H25ClN6O3
    Colore e forma:Solid
    Peso molecolare:480.95

    Ref: TM-T63178

  • EGFR-IN-89
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    EGFR-IN-89

    CAS:
    EGFR-IN-89 (compound 13k) is a fourth-generation inhibitor selectively targeting EGFR mutations, exhibiting potent activity with an IC50 of 10.1 nM against
    Formula:C26H31FN8O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:538.64

    Ref: TM-T79775

  • PF-00337210
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    PF-00337210

    CAS:
    <p>PF-00337210, an oral VEGFR2 inhibitor, may hinder endothelial and tumor cell growth, reducing angiogenesis and potentially causing cancer cell death.</p>
    Formula:C26H27N3O5
    Colore e forma:Solid
    Peso molecolare:461.51

    Ref: TM-T68546

  • VEGFR-2-IN-20
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    VEGFR-2-IN-20

    CAS:
    <p>VEGFR-2-IN-20 (Compound 7) is a highly effective VEGFR inhibitor with significant potential for cancer research [1].</p>
    Formula:C20H20N4O3S
    Colore e forma:Solid
    Peso molecolare:396.46

    Ref: TM-T61861

  • SB-220025 trihydrochloride
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    SB-220025 trihydrochloride

    CAS:
    SB-220025 trihydrochloride is an effective and specific human p38 mitogen-activated protein kinase inhibitor.
    Formula:C18H22Cl3FN6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:447.77

    Ref: TM-T24762

  • WB-308
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    WB-308

    CAS:
    WB-308 is an EGFR inhibitor that acts by decreasing NSCLC cell proliferation and colony formation and causing G2/M arrest and apoptosis.
    Formula:C19H17FN2O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:308.35

    Ref: TM-T23726

  • Tyrphostin AG 568
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    Tyrphostin AG 568

    CAS:
    Tyrphostin AG 568 promotes Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity. It also induces K562 to differentiate.
    Formula:C13H9N5O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:267.24

    Ref: TM-T24912

  • Logo CymitQuimica
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    Depatuxizumab mafodotin

    CAS:
    Depatuxizumab mafodotin, an antibody-drug conjugate (ADC) targeting the epidermal growth factor receptor (EGFR), is utilized in cancer research [1].
    Colore e forma:Liquid

    Ref: TM-T9901A-027

  • YH-306
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    YH-306

    CAS:
    <p>YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.</p>
    Formula:C19H18N2O2
    Purezza:98.06%
    Colore e forma:Solid
    Peso molecolare:306.36

    Ref: TM-T24642

  • EMI56
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    EMI56

    CAS:
    EMI56, a derivative of EMI1, exhibits enhanced potency against mutant EGFR compared to EMI1. Additionally, EMI56 effectively inhibits EGFR triple mutants[1].
    Formula:C21H20N2O3
    Colore e forma:Solid
    Peso molecolare:348.4

    Ref: TM-T35913

  • BMS-605541
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    BMS-605541

    CAS:
    <p>BMS-605541 is a potent and selective inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) kinase activity(Ki=49 nM).</p>
    Formula:C19H17F2N5OS
    Purezza:98.07%
    Colore e forma:Solid
    Peso molecolare:401.43

    Ref: TM-T26852

  • LY 456236 hydrochloride
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    LY 456236 hydrochloride

    CAS:
    LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM.
    Formula:C16H16ClN3O2
    Purezza:99.95%
    Colore e forma:Solid
    Peso molecolare:317.77

    Ref: TM-T22954

  • Larotinib
    Targetmol
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    Larotinib

    CAS:
    Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.
    Formula:C24H26ClFN4O4
    Purezza:99.73%
    Colore e forma:Solid
    Peso molecolare:488.94

    Ref: TM-T73334

  • EGFR-IN-11
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    EGFR-IN-11

    CAS:
    EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.
    Formula:C29H35N9O2S
    Purezza:99.93%
    Colore e forma:Solid
    Peso molecolare:573.71

    Ref: TM-T11158