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Angiogenesi

Angiogenesi

Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.

Sottocategorie di "Angiogenesi"

Mostrare 6 più sottocategorie

Trovati 2002 prodotti di "Angiogenesi"

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  • HDHD4-IN-1
    Targetmol
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    HDHD4-IN-1

    CAS:
    HDHD4-IN-1 (compound 3) is an inhibitor of N-acetylneuraminate-9-phosphate phosphatase (HDHD4) with an IC50 value of 11 μM. It is utilized in the research of neurological disorders.
    Formula:C12H22NO11P
    Colore e forma:Solid
    Peso molecolare:387.28

    Ref: TM-T201744

  • Logo CymitQuimica
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    FGFR4-IN-9

    FGFR4-IN-9 is a selective inhibitor of FGFR4 (IC50: 75.3 nM) that effectively inhibits the growth and angiogenesis of hepatocellular carcinoma cells.
    Formula:C24H22ClF3N4O4
    Colore e forma:Solid
    Peso molecolare:522.9

    Ref: TM-T63662

  • Logo CymitQuimica
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    VEGFR-2/DHFR-IN-2

    VEGFR-2/DHFR-IN-2 inhibits VEGFR-2 & DHFR (IC50: 0.623 & 9.085 μM), toxic to C26, HepG2, MCF7 cells (IC50: 3.59-8.38 μM), promising for cancer study.
    Formula:C21H21NO4
    Colore e forma:Solid
    Peso molecolare:351.4

    Ref: TM-T61229

  • BMS-066
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    BMS-066

    CAS:
    BMS-066 is an IKKβ/Tyk2 pseudokinase inhibitor. With IC50s of 9 nM and 72 nM, respectively.
    Formula:C19H21N7O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:379.42

    Ref: TM-T14669

  • JAK3/BTK-IN-7
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    JAK3/BTK-IN-7

    CAS:
    JAK3/BTK-IN-7 (XL-12), characterized as a JAK3/BTK inhibitor, exhibits IC 50 values of 2 nM and 14 nM for JAK3 and BTK respectively. This compound demonstrates anti-inflammatory properties and is applicable in research related to rheumatoid arthritis [1].
    Formula:C29H30N8O4
    Colore e forma:Solid
    Peso molecolare:554.6

    Ref: TM-T86758

  • TYK2 ligand 2
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    TYK2 ligand 2

    CAS:
    <p>TYK2ligand 2 is the TYK2 ligand of PROTACTYD-68. TYD-68 is a highly potent and selective CRBN-recruiting TYK2 PROTAC degrader with a DC50 value of 0.42 nM.</p>
    Formula:C24H20FN7O4
    Colore e forma:Solid
    Peso molecolare:489.458

    Ref: TM-T206678

  • Logo CymitQuimica
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    VEGFR-2-IN-17

    VEGFR-2-IN-17 (15a) is a potent VEGFR-2 inhibitor with an IC50 of 67.25 nM, showing significant antitumor effects.
    Formula:C21H14ClN3O2
    Colore e forma:Solid
    Peso molecolare:375.81

    Ref: TM-T61542

  • Logo CymitQuimica
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    FGFR4-IN-10

    FGFR4-IN-10 (compound 5a) is a potent, selective FGFR4 inhibitor with IC50 of 70.7 nM, sparing FGFR1-3.
    Formula:C20H19F3N6O3
    Colore e forma:Solid
    Peso molecolare:448.4

    Ref: TM-T62682

  • Brefeldin A 4-O-nicotinate
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    Brefeldin A 4-O-nicotinate

    CAS:
    Brefeldin A 4-O-nicotinate (CHNQD-01228) is a dual inhibitor of Arf1 and BMX proteins with an IC50 value of 0.22 μM for T24 cell proliferation. It also suppresses T24 cell migration and colony formation in a dose-dependent manner, induces G1 phase arrest, and triggers apoptosis. By targeting BMX proteins, it inhibits the AKT/p-AKT and STAT3/p-STAT3 signaling pathways, while also inhibiting Arf1 proteins to eliminate bladder cancer stem cells and activate antitumor immunity, thus exhibiting anticancer activity. Brefeldin A 4-O-nicotinate is applicable in research related to bladder cancer.
    Formula:C22H27NO5
    Colore e forma:Solid
    Peso molecolare:385.453

    Ref: TM-T206652

  • ALK ligand-Linker Conjugate 1
    Targetmol
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    ALK ligand-Linker Conjugate 1

    CAS:
    ALK ligand-Linker Conjugate 1 is an ALK ligand-connector conjugate used for the synthesis of PROTACALK degrader-4.
    Formula:C36H45N5O3
    Colore e forma:Solid
    Peso molecolare:595.77

    Ref: TM-T212133

  • EGFR/VEGFR2-IN-3
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    EGFR/VEGFR2-IN-3

    CAS:
    EGFR/VEGFR2-IN-3 (compound 9) is an effective inhibitor of EGFR and VEGFR-2, demonstrating IC50 values of 0.129 µM for EGFR, 0.142 µM for VEGFR-2, and 3.428 µM for COX-2. This compound exhibits cytotoxic properties and induces cell apoptosis (apoptosis) as well as cell cycle arrest at the G2/M phase.
    Formula:C24H20ClN5O2S2
    Colore e forma:Solid
    Peso molecolare:510.03

    Ref: TM-T201562

  • Logo CymitQuimica
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    FAK-IN-4

    FAK-IN-4 (Compound 7d) has anticancer activities that can induce cell apoptosis. FAK-IN-4 is potential inhibitor of FAK [1].
    Formula:C20H22N4O
    Colore e forma:Solid
    Peso molecolare:334.41

    Ref: TM-T61019

  • Tandutinib sulfate
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    Tandutinib sulfate

    CAS:
    Tandutinib (MLN518) sulfate is an effective and selective inhibitor of FLT3, with an IC50 value of 0.22 μM. It also inhibits c-Kit and PDGFR, displaying IC50 values of 0.17 μM and 0.20 μM respectively. This compound can be utilized in the treatment of acute myeloid leukemia and has the capability to cross the blood-brain barrier.
    Formula:C31H44N6O8S
    Colore e forma:Solid
    Peso molecolare:660.78

    Ref: TM-T201851

  • D-69491 hydrochloride
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    D-69491 hydrochloride

    CAS:
    D-69491 hydrochloride is an inhibitor of HER-2 tyrosine kinase activity, blocking the phosphorylation of HER-2 and inhibiting the proliferation of SKOV-3 cells. It exhibits antitumor activity.
    Formula:C25H26Cl2FN7O3
    Colore e forma:Solid
    Peso molecolare:562.42

    Ref: TM-T201568

  • Hypothemycin
    Targetmol
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    Hypothemycin

    CAS:
    Hypothemycin, a fungal polyketide, inhibits multiple kinases (VEGFR, MEK, FLT-3, PDGFR, ERK) with Kis ranging from 10 nM to 2.4 μM.
    Formula:C19H22O8
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:378.37

    Ref: TM-T15542

  • CEE321
    Targetmol
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    CEE321

    CAS:
    CEE321 is an effective pan-JAK inhibitor with an IC50 of 54 nM. It effectively inhibits biomarkers associated with atopic dermatitis.
    Formula:C18H16ClN5O
    Colore e forma:Solid
    Peso molecolare:353.806

    Ref: TM-T204824

  • 7PPD-Q
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    7PPD-Q

    CAS:
    7PPD-Q is a substituted p-phenylenediamine antioxidant derivative. It exhibits toxicity towards the bacterium V. fischeri (EC50= 14.9 mg/L).
    Formula:C19H24N2O2
    Colore e forma:Solid
    Peso molecolare:312.41

    Ref: TM-T201775

  • FGFR-IN-15
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    FGFR-IN-15

    FGFR-IN-15 (compound 18i) acts as a pan-FGFR inhibitor, exhibiting potent inhibitory activity against FGFR1-4.
    Formula:C22H23N5O5S
    Colore e forma:Solid
    Peso molecolare:469.51

    Ref: TM-T201821

  • Pred17
    Targetmol
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    Pred17

    Pred17 is an effective EGFR inhibitor with potential applications in lung cancer research.
    Formula:C27H22BN3O
    Colore e forma:Solid
    Peso molecolare:415.29

    Ref: TM-T201786

  • Logo CymitQuimica
    Targetmol
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    BTK-IN-8

    BTK-IN-8: potent, selective covalent BTK inhibitor; IC50=0.22 nM, Kd=0.91 nM; effective in blood CD69 cells (IC50=0.029 μM).
    Formula:C26H36N6O3
    Colore e forma:Solid
    Peso molecolare:480.6

    Ref: TM-T63173