p53
Gli inibitori di p53 prendono di mira la proteina p53, un soppressore tumorale che svolge un ruolo cruciale nella regolazione del ciclo cellulare, nella riparazione del DNA e nell'apoptosi. Sebbene p53 sia spesso mutato o inattivato nelle cellule tumorali, la sua inibizione è talvolta necessaria per proteggere le cellule sane dall'apoptosi durante determinati trattamenti. D'altra parte, il ripristino della funzione di p53 nei tumori può portare all'apoptosi delle cellule cancerose. La ricerca sugli inibitori di p53 è complessa e significativa sia per comprendere i meccanismi del cancro sia per sviluppare nuove terapie. Presso CymitQuimica, offriamo una selezione di inibitori e modulatori di p53 di alta qualità per supportare la tua ricerca in biologia del cancro, apoptosi e sviluppo
Trovati 63 prodotti di "p53"
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Amifostine
CAS:Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.Formula:C5H15N2O3PSPurezza:99.59%Colore e forma:White SolidPeso molecolare:214.22Quinacrine dihydrochloride
CAS:Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplasticFormula:C23H30CLN3O·2HClPurezza:98.24% - 99.80%Colore e forma:Yellow Crystals Or PowderPeso molecolare:472.88MT 63-78
CAS:<p>MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM).</p>Formula:C21H14N2O2Purezza:97.11%Colore e forma:SolidPeso molecolare:326.35NSC-87877
CAS:NSC-87877 inhibits Shp2 (IC50=0.318μM), Shp1 (IC50=0.355μM), and DUSP26 phosphatases.Formula:C19H13N3O7S2Purezza:97.35%Colore e forma:SolidPeso molecolare:459.45Etoposide
CAS:<p>Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM).</p>Formula:C29H32O13Purezza:99.19% - 99.94%Colore e forma:Crystals From Methanol SolidPeso molecolare:588.56Chlorambucil
CAS:Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard.Formula:C14H19Cl2NO2Purezza:97.37% - 98.45%Colore e forma:Off-White Slightly Granular Powder Melting Point 65-69°CPeso molecolare:304.21Unesbulin
CAS:<p>Unesbulin (PTC596) is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1).</p>Formula:C19H13F5N6Purezza:98.71%Colore e forma:SolidPeso molecolare:420.34Transcription Factor-Targeted Compound Library
Well-chosen xnum compounds with unique structures targeting transcription factor;Colore e forma:Odour SolidApoptosis Compound Library
A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;Colore e forma:Odour SolidTetrofosmin
CAS:Tetrofosmin is a phosphine developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds.Formula:C18H40O4P2Colore e forma:SolidPeso molecolare:382.46p53 (17-26)
CAS:Peptide is p53's amino acids 17-26, contacts Mdm-2 binding domain, also called p53N.Formula:C60H90N12O17Purezza:98%Colore e forma:SolidPeso molecolare:1251.43UNC 0631
CAS:UNC 0631 is a effectvie histone methyltransferase G9a inhibitor (IC50=4 nM).Formula:C37H61N7O2Purezza:97.42%Colore e forma:SolidPeso molecolare:635.93ReACp53 acetate
ReACp53 acetate could inhibit p53 amyloid formation and rescue p53 function in cancer cell lines.Formula:C110H210N52O26Purezza:99.55%Colore e forma:SolidPeso molecolare:2677.18BMH-7 HCl
BMH-7 HCl is a p53 activator, showing anti-cancer activity by activating the p53 pathway.Formula:C20H22ClN5OPurezza:99.62%Colore e forma:SolidPeso molecolare:383.88Anti-p53 Antibody (9G324)
Anti-p53 Antibody (9G324) is an antibody targeting p53. Anti-p53 Antibody (9G324) can be used in ELISA, IF.Colore e forma:Odour LiquidAnti-p53 Antibody (8C308)
Anti-p53 Antibody (8C308) is an antibody targeting p53. Anti-p53 Antibody (8C308) can be used in ELISA, WB, IF, FCM.Colore e forma:Odour LiquidAnti-p53 Antibody (9G129)
Anti-p53 Antibody (9G129) is a Rabbit antibody targeting p53. Anti-p53 Antibody (9G129) can be used in IHC-P,ICC/IF.Colore e forma:Odour LiquidAnti-Phospho-TP53 (Ser33) Antibody (4K787)
Anti-Phospho-TP53 (Ser33) Antibody (4K787) is an antibody targeting Phospho-TP53 (Ser33). Anti-Phospho-TP53 (Ser33) Antibody (4K787) can be used in ELISA, IHC, IF.Colore e forma:Odour LiquidAnti-p53 Antibody (2V863)
Anti-p53 Antibody (2V863) is a Mouse antibody targeting p53. Anti-p53 Antibody (2V863) can be used in ELISA,ELISA(Det).Colore e forma:Odour LiquidAnti-p53 Antibody (3K688)
<p>Anti-p53 Antibody (3K688) is a Rabbit antibody targeting p53. Anti-p53 Antibody (3K688) can be used in WB,ELISA,IP.</p>Colore e forma:Odour Liquid
