Caspasi

AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.

Biotin-VAD-FMK is a cell-permeable, irreversible biotin-labeled inhibitor of caspase. It is used to identify active …

Z-DEVD-FMK is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, …

Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α …

Duocarmycin A, an antitumor antibiotic, is a DNA alkylator and efficiently alkylates adenine N3 at …

1. Daphnoretin has strong antiviral activity, mainly on the later phase of the replication cycle. …

CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell …

Emricasan is an effective and irreversible pan-caspase inhibitor.

1. Glaucocalyxin A-SBE-β-CD could be useful with a better solubility and sustained function in drug …

1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, …

1. Aristololactam I has cytotoxic potency, mediated through the induction of apoptosis in a caspase …

Puerarin 6''-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice, it has significant antitumour activities, the …

Nivalenol is classified as type B trichotecenes toxins produced by Fusarium graminearum.

Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK …

Taurochenodeoxycholic acid is one of the main bioactive substances of animals' bile acid.

Chelidonic acid is a component of Chelidonium majus L., used as a mild analgesic, an …

TC11 is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis via …

Effusol is a natural product, exhibits potent scavenging activity for DPPH and ABTS radicals(IC50 values …

J22352 promotes HDAC6 degradation and induces anticancer effects by inhibiting autophagy and eliciting the antitumor …

Q-VD-OPha is a pan-caspase inhibitor with potent antiapoptotic properties.

Taurohyodeoxycholic acid sodium salt hydrate prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well …

Z-IETD-FMK is a selective caspase 8 inhibitor, which has cell permeable.

Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ …

Lycopodine inhibits proliferation of HeLa cells through induction of apoptosis via caspase-3 activation. Lycopodine, a …

15-acetoxyscirpenol is one of acetoxyscirpenol moiety mycotoxins (ASMs), showed strongly induces apoptosis and inhibits Jurkat …

Curzerenone holds great promise for use in chemopreventive and chemotherapeutic strategies, it has slightly effective …

2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification …

Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor. It inhibits cleavage of PARP, preventing apoptosis …

Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent …

EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 …

Quinovic acid shows some anti-tumour activities, quinovic acid glycosides have a potent inhibitory effect on …

Canthin-6-one has antimicrobial, cytotoxic, antiproliferative and proapoptotic effects, possibly by interfering with the G2/M transition; …

1. Soyasaponin Bb can suppress Eca-976 cell growth, reverse effects on over expression of c-met, …

Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. Sophoflavescenol …

Crocin has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of …

VX-765 is an orally active IL-converting enzyme/caspase-1 inhibitor.

The role of our hybrid molecules, an analogue of Salvianolic acid F, in compelling the …

Z-WEHD-FMK is a cell-permeable and irreversible inhibitor of caspase-1/5. It also shows a robust inhibitory …

Licochalcone A is a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch …

Ac-DEVD-CHO is a selective Caspase-3 inhibitor (Ki: 230 pM).

Tasisulam is an apoptosis inducer and an antitumor agent via the intrinsic pathway.

Scutebarbatine A shows significant antitumor effects on A549 cells in vivo and in vitro via …

Furowanin A shows significant cytotoxicity against HL-60 cells, it induces that Caspase-9 and caspase-3 inhibitors …

3,5-Dicaffeoyl-epi-quinic acid shows anti-inflammatory activity, it may improve mast cell-mediated inflammatory diseases.

Neochamaejasmin A can inhibit cellular (3)H-thymidine incorporation (IC 50 12.5 microg/mL) and subsequent proliferation of …

Cedrusin shows a cytotoxic effect on A375 and HeLa cells.

Juncusol shows anxiolytic and sedative activities, it shows anxiolytic activity at dosages of 10 mg/kg; …

Santamarine has significant anticancer activity, can inhibit L1210 cells because of its cytotoxic,cytostatic and blocking …

(-)-Centrolobol has antifibrotic activity, it can significantly inhibit the proliferation of HSC-T6 cells in a …

Regiolone demonstrates phytotoxicity. Regiolone also has anti-proliferative and apoptotic activities, it can induce apoptosis in …

Paeoniflorigenone is a depolarizing neuromuscular blocking agent, being similar to succinylcholine.

28-Deoxonimbolide exhibits potent cytotoxic activity against HL60 leukemia cells.

Ganoderic acid X is a potential Mdm2 inhibitor(K(i) = 16nM). It is a potential anticancer …

Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and …

Caspase-3 Inhibitor I is a specific inhibitor of Caspase-3.

Taurohyodeoxycholic acid sodium salt, a hydrophilic bile salt, on bile salt and biliary lipid secretion …

Polyphyllin B is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor …

Z-VAD-FMK (Caspase Inhibitor VI) is an irreversible pan-caspase inhibitor.

Tauroursodeoxycholate Sodium is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones …

Senegenin is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and …

Beta-Tocotrienol to serve as a new anticancer agent for treating human lung and brain cancers. …

(-)-Zeylenol shows antifeedant activity. Zeylenol shows inhibitory activity toward the root growth of Lactuca sativa. …

1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic …

5,7,4'-Trimethoxyflavone is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.

Apoptosis Activator 2 is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA …