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Caspasi

Caspasi

Gli inibitori delle caspasi sono composti che bloccano l'attività delle caspasi, una famiglia di proteasi che sono esecutori centrali dell'apoptosi. Le caspasi clivano substrati specifici all'interno della cellula per innescare il processo apoptotico, portando alla morte cellulare programmata. Gli inibitori delle caspasi sono utilizzati per studiare i meccanismi dell'apoptosi, nonché per prevenire la morte cellulare indesiderata in vari modelli di ricerca. Questi inibitori sono anche esplorati in contesti terapeutici per proteggere le cellule dall'apoptosi in malattie come la neurodegenerazione. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle caspasi di alta qualità per supportare la tua ricerca in apoptosi, morte cellulare e campi correlati.

Trovati 143 prodotti di "Caspasi"

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  • Oxidopamine hydrochloride

    CAS:
    Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.
    Formula:C8H12ClNO3
    Purezza:98.34% - 99.85%
    Colore e forma:Physical Description Beige Solid (Ntp 1992)
    Peso molecolare:205.64
  • ML-9

    CAS:
    <p>ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively.</p>
    Formula:C15H18Cl2N2O2S
    Purezza:99.69%
    Colore e forma:Crystalline Solid
    Peso molecolare:361.29
  • Dehydrocorydaline chloride

    CAS:
    <p>Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.</p>
    Formula:C22H24ClNO4
    Purezza:99.53%
    Colore e forma:Solid
    Peso molecolare:401.88
  • Terfenadine

    CAS:
    Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.
    Formula:C32H41NO2
    Purezza:98.76% - 99.75%
    Colore e forma:Solid
    Peso molecolare:471.67
  • Diclofenac

    CAS:
    Diclofenac: a nonsteroidal compound inhibiting COX-1 and COX-2, reducing pro-inflammatory prostaglandins.
    Formula:C14H11Cl2NO2
    Purezza:99.69% - 99.97%
    Colore e forma:Crystals From Ether-Petroleum Ether Solid
    Peso molecolare:296.15
  • Fenbufen

    CAS:
    <p>Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis.</p>
    Formula:C16H14O3
    Purezza:98.35% - 98.46%
    Colore e forma:White Solid
    Peso molecolare:254.28
  • Diclofenac sodium

    CAS:
    <p>Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.</p>
    Formula:C14H10Cl2NNaO2
    Purezza:98.21% - 99.73%
    Colore e forma:White Or Off-White Powder
    Peso molecolare:318.13
  • Aspirin

    CAS:
    Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.
    Formula:C9H8O4
    Purezza:99.78% - 99.91%
    Colore e forma:White Solid Crystalline
    Peso molecolare:180.16
  • Crustecdysone

    CAS:
    <p>Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.</p>
    Formula:C27H44O7
    Purezza:99.06% - 99.67%
    Colore e forma:Canary Yellow Fine Powder
    Peso molecolare:480.63
  • Oxidopamine hydrobromide

    CAS:
    <p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>
    Formula:C8H12BrNO3
    Purezza:98.22% - 99.88%
    Colore e forma:Beige To Brown Fine Crystalline Powder
    Peso molecolare:250.09
  • Q-VD-OPH

    CAS:
    <p>Q-VD-OPh is an irreversible caspase inhibitor with an IC50 value of 48 nM against caspase-7 and between 25 and 400 nM against caspase-1, 3, 8, 9, 10, 12.</p>
    Formula:C26H25F2N3O6
    Purezza:97.8% - 98.95%
    Colore e forma:Solid
    Peso molecolare:513.5
  • Diclofenac diethylamine

    CAS:
    Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).
    Formula:C18H22Cl2N2O2
    Purezza:99.81% - 99.87%
    Colore e forma:Solid
    Peso molecolare:369.29
  • Ac-YVAD-CMK

    CAS:
    <p>Ac-YVAD-CMK: Irreversible Caspase-1 inhibitor; halts pyroptosis, IL-1β/IL-18; neuroprotective and anti-inflammatory.</p>
    Formula:C24H33ClN4O8
    Purezza:97.08% - 99.909%
    Colore e forma:Solid
    Peso molecolare:540.99
  • Ac-FLTD-CMK

    CAS:
    <p>Ac-FLTD-CMK, an abscisicin D derivative, selectively inhibits inflammatory caspases-1, -4, and -11 (IC50: 46.7 nM, 1.49 μM, 329 nM) but not caspase-3.</p>
    Formula:C26H37ClN4O8
    Purezza:95.17%
    Colore e forma:Solid
    Peso molecolare:569.05
  • Lacidipine

    CAS:
    Lacidipine (SN-305) is a slow-acting, long-duration lipophilic dihydropyridine calcium blocker that prevents reflex tachycardia and lowers blood pressure.
    Formula:C26H33NO6
    Purezza:99.98%
    Colore e forma:White-To-Off-White Crystalline Solid
    Peso molecolare:455.54
  • Thiabendazole

    CAS:
    <p>Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.</p>
    Formula:C10H7N3S
    Purezza:99.14%
    Colore e forma:Light Yellow Powder
    Peso molecolare:201.25
  • Apoptosis Compound Library


    A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;
    Colore e forma:Odour Solid
  • Ac-VDVAD-CHO TFA


    Ac-VDVAD-CHO (TFA) is a caspase-2/3 inhibitor with IC50 values of 46 nM and 15 nM, respectively.
    Colore e forma:Odour Solid
  • Ac-LEHD-AMC

    CAS:
    Ac-LEHD-AMC, a fluorogenic caspase-9 substrate, releases fluorescent AMC upon cleavage, aiding caspase-9 activity measurement.
    Formula:C33H41N7O11
    Colore e forma:Solid
    Peso molecolare:711.729
  • Protease Inhibitor Library


    A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
    Colore e forma:Odour Solid
  • Pralnacasan

    CAS:
    Pralnacasan blocks IL-18, IL-1β, IFN-γ. It’s a potent oral enzyme inhibitor with use in arthritis therapy (Ki: 1.4 nM).
    Formula:C26H29N5O7
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:523.54
  • Z-WEHD-FMK

    CAS:
    Z-WEHD-FMK is a cell-permeable and irreversible inhibitor of caspase-1/5. It also shows a robust inhibitory effect on cathepsin B activity (IC50: 6 μM).
    Formula:C37H42FN7O10
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:763.78
  • Z-VDVA-(DL-Asp)-FMK

    CAS:
    Z-VDVA-(DL-Asp)-FMK is a derivative compound of Z-VDVAD-FMK specifically designed as an inhibitor targeting caspase-2.
    Formula:C32H46FN5O11
    Colore e forma:Solid
    Peso molecolare:695.742
  • TD1092


    TD1092, a pan-IAP degrader, activates caspase 3/7, induces apoptosis in cancer cells, inhibits NF-κB, and is used in cancer research.
    Formula:C55H70N8O9
    Colore e forma:Solid
    Peso molecolare:987.19
  • Sanggenon G

    CAS:
    Sanggenon G inhibits XIAP by binding its BIR3 domain; affinity is 34.26 μM, boosting caspase activation.
    Formula:C40H38O11
    Colore e forma:Solid
    Peso molecolare:694.72
  • TNF-α-IN-11


    TNF-α-IN-11 (Compound 10) is a TNF-α inhibitor exhibiting a dissociation constant (K D) of 12.06 μM.
    Formula:C24H26N2O5
    Colore e forma:Solid
    Peso molecolare:422.47
  • Ac-Trp-Glu-His-Asp-Aldehyde

    CAS:
    <p>Ac-Trp-Glu-His-Asp-Aldehyde is a powerful and selective inhibitor of caspase-1, demonstrating a K_i value of 56 pM [1] [2].</p>
    Formula:C28H33N7O9
    Colore e forma:Solid
    Peso molecolare:611.6
  • IRF1-IN-2

    CAS:
    <p>IRF1-IN-2 is a small molecule IRF1 inhibitor that suppresses pyroptosis, protecting against radiation-induced skin damage.</p>
    Formula:C18H20N2O4S
    Purezza:99.85%
    Colore e forma:Solid
    Peso molecolare:360.43
  • Reproxalap

    CAS:
    <p>Reproxalap (NS-2) is a dry eye treatment that neutralizes aldehydes like malondialdehyde.</p>
    Formula:C12H13ClN2O
    Purezza:99.4% - 99.97%
    Colore e forma:Solid
    Peso molecolare:236.7
  • Ac-LEVD-CHO

    CAS:
    <p>Ac-LEVD-CHO, a caspase-4 inhibitor, is a peptide with the sequence Ac-Leu-Glu-Val-Asp-al [1].</p>
    Formula:C22H36N4O9
    Colore e forma:Solid
    Peso molecolare:500.54
  • Boc-Asp(OBzl)-CMK

    CAS:
    Boc-Asp(OBzl)-CMK, an inhibitor of IL-1 converting enzyme (ICE, caspase1), prevents the death of CHP100 neuroblastoma cells and inhibits IL-1β release induced by the viral coat protein [1].
    Formula:C17H22ClNO5
    Colore e forma:Solid
    Peso molecolare:355.81
  • Ac-IEPD-AFC

    CAS:
    Ac-IEPD-AFC (IEPD) is a fluorescent substrate for granzyme B and can be used to measure granzyme B activity.
    Formula:C32H38F3N5O11
    Purezza:99.16%
    Colore e forma:Solid
    Peso molecolare:725.67
  • PQ401

    CAS:
    <p>PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50&lt;1 μM).</p>
    Formula:C18H16ClN3O2
    Purezza:99.77%
    Colore e forma:Solid
    Peso molecolare:341.79
  • Diethylnorspermine HCl

    CAS:
    Diethylnorspermine HCl (N1,N11-Diethylnorspermine tetrahydrochloride) potently induces SSAT (spermidine/spermine N1-acetyltransferase) mRNA and effectively
    Formula:C13H36Cl4N4
    Purezza:99.79% - 99.86%
    Colore e forma:Solid
    Peso molecolare:390.26
  • Ac-WEHD-AFC TFA


    Ac-WEHD-AFC TFA: a fluorogenic substrate detecting caspase-1 activity, used in tumor and inflammation research.
    Formula:C40H38F6N8O13
    Colore e forma:Solid
    Peso molecolare:952.77
  • Biotin-DEVD-CHO TFA


    Biotin-DEVD-CHO (TFA) is the biotin-conjugated form of the caspase-3 and caspase-7 inhibitor Ac-DEVD-CHO. It can be utilized for affinity purification of active caspase-3, -6, -7, and -8 and is also applicable for in vitro detection of active caspase-3.
    Colore e forma:Odour Solid
  • Roxatidine

    CAS:
    Roxatidine, a metabolite of Roxatidine acetate, is a H2-receptor antagonist that prevents ulcers and has anti-inflammatory properties.
    Formula:C17H26N2O3
    Colore e forma:Solid
    Peso molecolare:306.4
  • Perfluorodecanoic acid

    CAS:
    Perfluorodecanoic acid is a biochemical.
    Formula:C10HF19O2
    Colore e forma:Physical Description Liquid (Ntp 1992)
    Peso molecolare:514.08
  • VCP/p97 IN-3


    VCP/p97 IN-3 is an allosteric inhibitor of VCP/p97. It exhibits inhibitory activity against VCP, with an IC50 of 9 nM, and shows IC50 values of 12 nM (N660K) and 19 nM (V474A/D649A) for mutant VCP proteins. VCP/p97 IN-3 increases the levels of K48 ubiquitination and caspase-3. It activates endoplasmic reticulum stress and the unfolded protein response (UPR). In a subcutaneous xenograft mouse model with RPMI-8226 cells, VCP/p97 IN-3 suppresses tumor growth. This compound is applicable for research in multiple myeloma.
    Colore e forma:Odour Solid
  • BOC-D-FMK

    CAS:
    Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM).
    Formula:C11H18FNO5
    Purezza:97.02%
    Colore e forma:Solid
    Peso molecolare:263.26
  • Trehalose-6,6'-dibehenate

    CAS:
    Trehalose-6,6'-dibehenate, a bioactive glycolipid, is applicable for the preparation of vaccine adjuvant [1].
    Formula:C56H106O13
    Peso molecolare:987.43
  • (Iso)-Z-VAD(OMe)-FMK

    CAS:
    (Iso)-Z-VAD(OMe)-FMK is an isomer of Z-VAD(OMe)-FMK, which is a pan-caspase inhibitor with irreversible properties. Z-VAD(OMe)-FMK is also an inhibitor UCHL1.
    Formula:C22H30FN3O7
    Purezza:97.10%
    Colore e forma:Soild
    Peso molecolare:467.49
  • IRF1-IN-1

    CAS:
    IRF1-IN-1 (Compound I-2) is an IRF1 inhibitor , inhibiting the cleavage of Caspase 1, GSDMD, IL-1, and PARP1,protecting against skin inflammatory damage.
    Formula:C22H24N4O4S
    Purezza:99.88%
    Colore e forma:Solid
    Peso molecolare:440.52
  • δ-secretase inhibitor 11

    CAS:
    <p>δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.</p>
    Formula:C10H12N4O2
    Purezza:99.84%
    Colore e forma:Solid
    Peso molecolare:220.23
  • AKN-028

    CAS:
    <p>AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.</p>
    Formula:C17H14N6
    Purezza:99.88%
    Colore e forma:Solid
    Peso molecolare:302.33
  • Caspase-3 activator 2


    <p>Caspase-3 Activator 2 (Compound 2f) is a caspase 3 activator with cytotoxic effects on HL-60 and K562 cells, exhibiting IC 50 values of 33.52 μM and 76.90 μM,</p>
    Purezza:98%
    Colore e forma:Odour Solid
  • Sarglaroids F


    Sarglaroids F (compound 6), an anti-inflammatory agent extracted from the roots of Grass Coral, suppresses LPS/ATP-induced IL-1β secretion by modulating K+
    Formula:C38H44O12
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:692.75
  • Almorexant hydrochloride

    CAS:
    Almorexant hydrochloride (ACT 078573 hydrochloride) is a dual orexin receptor antagonist that induces apoptosis and can be used to study sleep disorders.
    Formula:C29H32ClF3N2O3
    Purezza:99.85%
    Colore e forma:Solid
    Peso molecolare:549.02
  • MX1013

    CAS:
    MX1013, a dipeptide pan-caspase inhibitor, inhibits caspase-1, -3, -6, -7, -8, and -9.
    Formula:C18H23FN2O6
    Colore e forma:Solid
    Peso molecolare:382.39
  • J22352

    CAS:
    J22352, a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM, enhances anticancer effects in
    Formula:C24H21N3O4
    Colore e forma:Solid
    Peso molecolare:415.44
  • Tauroursodeoxycholate

    CAS:
    Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.
    Formula:C26H45NO6S
    Purezza:98.77% - 99.93%
    Colore e forma:White Solid
    Peso molecolare:499.7
  • Diclofenac Potassium

    CAS:
    Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
    Formula:C14H10Cl2KNO2
    Purezza:99.51%
    Colore e forma:White To Yellowish Crystalline Powder
    Peso molecolare:334.24
  • CASP3 Activator 1541

    CAS:
    CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.
    Formula:C24H17N3O4
    Purezza:98.84%
    Colore e forma:Solid
    Peso molecolare:411.41
  • 5,​7,​4'-​Trimethoxyflavone

    CAS:
    <p>5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.</p>
    Formula:C18H16O5
    Purezza:97.53%
    Colore e forma:Solid
    Peso molecolare:312.32
  • L67

    CAS:
    <p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>
    Formula:C16H14Br2N4O4
    Purezza:98.34% - 99.56%
    Colore e forma:Solid
    Peso molecolare:486.11
  • Aristolactam I

    CAS:
    <p>Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway.</p>
    Formula:C17H11NO4
    Purezza:98.98% - 99.63%
    Colore e forma:Solid
    Peso molecolare:293.27
  • Z-FA-FMK

    CAS:
    Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.
    Formula:C21H23FN2O4
    Purezza:98.84% - 99.68%
    Colore e forma:Solid
    Peso molecolare:386.42
  • Phenoxodiol

    CAS:
    Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)
    Formula:C15H12O3
    Purezza:98.07% - 99.18%
    Colore e forma:Solid
    Peso molecolare:240.25
  • Emricasan

    CAS:
    Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.
    Formula:C26H27F4N3O7
    Purezza:98.13% - 99%
    Colore e forma:Solid
    Peso molecolare:569.5
  • Almorexant

    CAS:
    Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.
    Formula:C29H31F3N2O3
    Purezza:97.75% - 98.02%
    Colore e forma:Solid
    Peso molecolare:512.56
  • Asperosaponin VI

    CAS:
    Asperosaponin VI, from Dipsacus asper rhizome, treats back pain, hematoma, and fractures.
    Formula:C47H76O18
    Purezza:97.15% - 99.79%
    Colore e forma:Solid
    Peso molecolare:929.10
  • Ossirene

    CAS:
    Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
    Formula:C2H4Cl3O2Te·H4N
    Purezza:≥98%
    Colore e forma:Solid
    Peso molecolare:312.05
  • Dehydrocorydaline

    CAS:
    <p>1.</p>
    Formula:C22H24NO4
    Purezza:99.84%
    Colore e forma:Solid
    Peso molecolare:366.43
  • Taurodeoxycholic acid sodium hydrate

    CAS:
    <p>Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.</p>
    Formula:C26H46NNaO7S
    Purezza:99.95%
    Colore e forma:Solid
    Peso molecolare:539.70
  • 5,7-Dihydroxychromone

    CAS:
    <p>1.</p>
    Formula:C9H6O4
    Purezza:99.76% - ≥95%
    Colore e forma:Solid
    Peso molecolare:178.14
  • Boc-Asp(OMe)-fluoromethyl ketone

    CAS:
    <p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>
    Formula:C11H18FNO5
    Purezza:≥98%
    Colore e forma:Solid
    Peso molecolare:263.26
  • (E/Z)-Necrosulfonamide

    CAS:
    <p>(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.</p>
    Formula:C18H15N5O6S2
    Purezza:97.62% - 98%
    Colore e forma:Solid
    Peso molecolare:461.47
  • KEA1-97

    CAS:
    <p>Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M).</p>
    Formula:C15H9Cl2FN4
    Purezza:97.07%
    Colore e forma:Solid
    Peso molecolare:335.16
  • Lobaplatin

    CAS:
    Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe.
    Formula:C9H18N2O3Pt
    Purezza:98.00%
    Colore e forma:Solid
    Peso molecolare:397.33
  • Ac-DEVD-AMC

    CAS:
    <p>Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .</p>
    Formula:C30H37N5O13
    Purezza:98.20%
    Colore e forma:White Powder
    Peso molecolare:675.64
  • PI-1840

    CAS:
    <p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>
    Formula:C22H26N4O3
    Purezza:98.82%
    Colore e forma:Solid
    Peso molecolare:394.47
  • Chelidonic acid

    CAS:
    Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.
    Formula:C7H4O6
    Purezza:99.03%
    Colore e forma:Solid
    Peso molecolare:184.10
  • Wedelolactone

    CAS:
    <p>Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.</p>
    Formula:C16H10O7
    Purezza:98.07% - 99.87%
    Colore e forma:Solid
    Peso molecolare:314.25
  • Sesamolin

    CAS:
    Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.
    Formula:C20H18O7
    Purezza:98.77% - 99.04%
    Colore e forma:Solid
    Peso molecolare:370.35
  • 2-HBA

    CAS:
    2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
    Formula:C17H14O3
    Purezza:99.76%
    Colore e forma:Solid
    Peso molecolare:266.29
  • Ac-DEVD-CHO acetate


    <p>Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.</p>
    Formula:C22H34N4O13
    Purezza:98.54%
    Colore e forma:Solid
    Peso molecolare:562.52
  • Z-DEVD-FMK

    CAS:
    Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7,
    Formula:C30H41FN4O12
    Purezza:96.19% - 99.69%
    Colore e forma:Solid
    Peso molecolare:668.66
  • Diethylnorspermine HBr

    CAS:
    DENSPM is a potent polyamine analog that induces SSAT, arrests the cell cycle, and triggers apoptosis in various cancer cells.
    Formula:C13H36Br4N4
    Colore e forma:Solid
    Peso molecolare:568.075
  • Arnicolide D

    CAS:
    Arnicolide D is a sesquiterpene lactone.
    Formula:C19H24O5
    Purezza:96.66% - 99.93%
    Colore e forma:Solid
    Peso molecolare:332.39
  • EF24

    CAS:
    EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.
    Formula:C19H15F2NO
    Purezza:99.71%
    Colore e forma:Solid
    Peso molecolare:311.33
  • PAC-1

    CAS:
    <p>PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.</p>
    Formula:C23H28N4O2
    Purezza:96.78% - 99.77%
    Colore e forma:Solid
    Peso molecolare:392.49
  • Ivachtin

    CAS:
    <p>Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining</p>
    Formula:C20H21N3O7S
    Purezza:99.74%
    Colore e forma:Solid
    Peso molecolare:447.46
  • Penicillic acid

    CAS:
    <p>Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.</p>
    Formula:C8H10O4
    Purezza:98%
    Colore e forma:Needles From Petroleum Ether Slight Yellow Powder
    Peso molecolare:170.16
  • Ginsenoside Rh2

    CAS:
    <p>Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.</p>
    Formula:C36H62O8
    Purezza:99.20% - 99.76%
    Colore e forma:White Powder
    Peso molecolare:622.87
  • Guggulsterone

    CAS:
    <p>Guggulsterone (Guggulsterone E&amp;Z) E&amp;Z is a 3-hydroxy steroid. It has a role as an androgen.</p>
    Formula:C21H28O2
    Purezza:99.4% - 99.8%
    Colore e forma:Light Yellow Powder
    Peso molecolare:312.45
  • AVN-944

    CAS:
    <p>AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.</p>
    Formula:C25H27N5O5
    Purezza:99.07% - ≥95%
    Colore e forma:Solid
    Peso molecolare:477.51
  • Z-IETD-FMK

    CAS:
    <p>Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.</p>
    Formula:C30H43FN4O11
    Purezza:95% - 99.81%
    Colore e forma:Solid
    Peso molecolare:654.68
  • Z-VAD-FMK

    CAS:
    <p>Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not</p>
    Formula:C21H28FN3O7
    Purezza:98.24% - 99.79%
    Colore e forma:Solid
    Peso molecolare:453.46
  • PHYTOSPHINGOSINE

    CAS:
    <p>Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.</p>
    Formula:C18H39NO3
    Purezza:99.81%
    Colore e forma:Solid
    Peso molecolare:317.51
  • TC11

    CAS:
    <p>TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis</p>
    Formula:C20H22N2O2
    Purezza:97.86%
    Colore e forma:Solid
    Peso molecolare:322.4
  • Z-VAD(OMe)-FMK

    CAS:
    <p>View and buy Z-VAD(OMe)-FMK from TargetMol.Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor.Cited in 10 publications.</p>
    Formula:C22H30FN3O7
    Purezza:95.92% - 99.71%
    Colore e forma:Solid
    Peso molecolare:467.49
  • Belnacasan

    CAS:
    Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.
    Formula:C24H33ClN4O6
    Purezza:96.53% - 99.5%
    Colore e forma:Solid
    Peso molecolare:508.99
  • Paris saponin VII

    CAS:
    <p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>
    Formula:C51H82O21
    Purezza:99.51% - 99.63%
    Colore e forma:Solid
    Peso molecolare:1031.18
  • Tauroursodeoxycholate sodium

    CAS:
    Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.
    Formula:C26H44NNaO6S
    Purezza:97.90%
    Colore e forma:Solid
    Peso molecolare:521.69
  • Daphnetin

    CAS:
    <p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>
    Formula:C9H6O4
    Purezza:97.47% - 99.8%
    Colore e forma:Solid
    Peso molecolare:178.14
  • Ac-DEVD-pNA

    CAS:
    Ac-DEVD-pNA is the preferred peptidic substrate for caspase-3.
    Formula:C26H34N6O13
    Purezza:>99.99%
    Colore e forma:White
    Peso molecolare:638.58
  • Senkyunolide I

    CAS:
    1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.
    Formula:C12H16O4
    Purezza:99.73% - 99.88%
    Colore e forma:Solid
    Peso molecolare:224.25
  • Z-YVAD-FMK

    CAS:
    AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.
    Formula:C31H39FN4O9
    Purezza:98.00%
    Colore e forma:Solid
    Peso molecolare:630.66
  • Dihydrocapsaicin

    CAS:
    Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.
    Formula:C18H29NO3
    Purezza:99.8% - ≥95%
    Colore e forma:White Crystal
    Peso molecolare:307.43
  • BC-1471

    CAS:
    BC-1471 is a STAMBP deubiquitinase inhibitor that blocks NALP7 inflammasome activity.
    Formula:C27H32N4O4S
    Purezza:99.98%
    Colore e forma:Solid
    Peso molecolare:508.63