Caspasi
Gli inibitori delle caspasi sono composti che bloccano l'attività delle caspasi, una famiglia di proteasi che sono esecutori centrali dell'apoptosi. Le caspasi clivano substrati specifici all'interno della cellula per innescare il processo apoptotico, portando alla morte cellulare programmata. Gli inibitori delle caspasi sono utilizzati per studiare i meccanismi dell'apoptosi, nonché per prevenire la morte cellulare indesiderata in vari modelli di ricerca. Questi inibitori sono anche esplorati in contesti terapeutici per proteggere le cellule dall'apoptosi in malattie come la neurodegenerazione. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle caspasi di alta qualità per supportare la tua ricerca in apoptosi, morte cellulare e campi correlati.
Trovati 144 prodotti di "Caspasi"
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MX1013
CAS:MX1013, a dipeptide pan-caspase inhibitor, inhibits caspase-1, -3, -6, -7, -8, and -9.Formula:C18H23FN2O6Colore e forma:SolidPeso molecolare:382.39Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purezza:97.47% - 99.8%Colore e forma:SolidPeso molecolare:178.14Chelidonic acid
CAS:Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.Formula:C7H4O6Purezza:99.03%Colore e forma:SolidPeso molecolare:184.10Almorexant
CAS:Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.Formula:C29H31F3N2O3Purezza:97.75% - 98.02%Colore e forma:SolidPeso molecolare:512.56Asperosaponin VI
CAS:Asperosaponin VI, from Dipsacus asper rhizome, treats back pain, hematoma, and fractures.Formula:C47H76O18Purezza:97.15% - 99.79%Colore e forma:SolidPeso molecolare:929.10Z-IETD-FMK
CAS:<p>Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.</p>Formula:C30H43FN4O11Purezza:95% - 99.81%Colore e forma:SolidPeso molecolare:654.68Ginsenoside Rh2
CAS:<p>Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.</p>Formula:C36H62O8Purezza:99.20% - 99.76%Colore e forma:White PowderPeso molecolare:622.872-HBA
CAS:2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.Formula:C17H14O3Purezza:99.76%Colore e forma:SolidPeso molecolare:266.29Ac-DEVD-AMC
CAS:<p>Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .</p>Formula:C30H37N5O13Purezza:98.20%Colore e forma:White PowderPeso molecolare:675.64KEA1-97
CAS:<p>Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M).</p>Formula:C15H9Cl2FN4Purezza:97.07%Colore e forma:SolidPeso molecolare:335.16Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Formula:C51H82O21Purezza:99.51% - 99.63%Colore e forma:SolidPeso molecolare:1031.18Z-VAD(OMe)-FMK
CAS:<p>View and buy Z-VAD(OMe)-FMK from TargetMol.Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor.Cited in 10 publications.</p>Formula:C22H30FN3O7Purezza:95.92% - 99.71%Colore e forma:SolidPeso molecolare:467.49PHYTOSPHINGOSINE
CAS:<p>Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.</p>Formula:C18H39NO3Purezza:99.81%Colore e forma:SolidPeso molecolare:317.51TC11
CAS:<p>TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis</p>Formula:C20H22N2O2Purezza:97.86%Colore e forma:SolidPeso molecolare:322.4Belnacasan
CAS:Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.Formula:C24H33ClN4O6Purezza:96.53% - 99.5%Colore e forma:SolidPeso molecolare:508.99AVN-944
CAS:<p>AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.</p>Formula:C25H27N5O5Purezza:99.07% - ≥95%Colore e forma:SolidPeso molecolare:477.51Ac-DEVD-pNA
CAS:Ac-DEVD-pNA is the preferred peptidic substrate for caspase-3.Formula:C26H34N6O13Purezza:>99.99%Colore e forma:WhitePeso molecolare:638.58Z-YVAD-FMK
CAS:AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.Formula:C31H39FN4O9Purezza:98.00%Colore e forma:SolidPeso molecolare:630.66Dihydrocapsaicin
CAS:Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.Formula:C18H29NO3Purezza:99.8% - ≥95%Colore e forma:White CrystalPeso molecolare:307.43Tauroursodeoxycholate
CAS:Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.Formula:C26H45NO6SPurezza:98.77% - 99.93%Colore e forma:White SolidPeso molecolare:499.7Diclofenac Potassium
CAS:Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.Formula:C14H10Cl2KNO2Purezza:99.51%Colore e forma:White To Yellowish Crystalline PowderPeso molecolare:334.24CASP3 Activator 1541
CAS:CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.Formula:C24H17N3O4Purezza:98.84%Colore e forma:SolidPeso molecolare:411.415,7,4'-Trimethoxyflavone
CAS:5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.Formula:C18H16O5Purezza:97.53%Colore e forma:SolidPeso molecolare:312.32L67
CAS:<p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>Formula:C16H14Br2N4O4Purezza:98.34% - 99.56%Colore e forma:SolidPeso molecolare:486.11Phenoxodiol
CAS:Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)Formula:C15H12O3Purezza:98.07% - 99.18%Colore e forma:SolidPeso molecolare:240.25Taurodeoxycholic acid sodium hydrate
CAS:<p>Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.</p>Formula:C26H46NNaO7SPurezza:99.95%Colore e forma:SolidPeso molecolare:539.705,7-Dihydroxychromone
CAS:1.Formula:C9H6O4Purezza:99.76% - ≥95%Colore e forma:SolidPeso molecolare:178.14Boc-Asp(OMe)-fluoromethyl ketone
CAS:<p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>Formula:C11H18FNO5Purezza:≥98%Colore e forma:SolidPeso molecolare:263.26(E/Z)-Necrosulfonamide
CAS:<p>(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.</p>Formula:C18H15N5O6S2Purezza:97.62% - 98%Colore e forma:SolidPeso molecolare:461.47Lobaplatin
CAS:Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe.Formula:C9H18N2O3PtPurezza:98.00%Colore e forma:SolidPeso molecolare:397.33Z-DEVD-FMK
CAS:Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7,Formula:C30H41FN4O12Purezza:96.19% - 99.69%Colore e forma:SolidPeso molecolare:668.66Diethylnorspermine HBr
CAS:DENSPM is a potent polyamine analog that induces SSAT, arrests the cell cycle, and triggers apoptosis in various cancer cells.Formula:C13H36Br4N4Colore e forma:SolidPeso molecolare:568.075Arnicolide D
CAS:Arnicolide D is a sesquiterpene lactone.Formula:C19H24O5Purezza:96.66% - 99.93%Colore e forma:SolidPeso molecolare:332.39EF24
CAS:EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.Formula:C19H15F2NOPurezza:99.71%Colore e forma:SolidPeso molecolare:311.33PAC-1
CAS:<p>PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.</p>Formula:C23H28N4O2Purezza:96.78% - 99.77%Colore e forma:SolidPeso molecolare:392.49Ivachtin
CAS:<p>Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining</p>Formula:C20H21N3O7SPurezza:99.74%Colore e forma:SolidPeso molecolare:447.46Penicillic acid
CAS:<p>Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.</p>Formula:C8H10O4Purezza:98%Colore e forma:Needles From Petroleum Ether Slight Yellow PowderPeso molecolare:170.16Guggulsterone
CAS:Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.Formula:C21H28O2Purezza:99.4% - 99.8%Colore e forma:Light Yellow PowderPeso molecolare:312.45Z-VAD-FMK
CAS:<p>Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not</p>Formula:C21H28FN3O7Purezza:98.24% - 99.79%Colore e forma:SolidPeso molecolare:453.46Tauroursodeoxycholate sodium
CAS:Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.Formula:C26H44NNaO6SPurezza:97.90%Colore e forma:SolidPeso molecolare:521.69Senkyunolide I
CAS:1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.Formula:C12H16O4Purezza:99.73% - 99.88%Colore e forma:SolidPeso molecolare:224.25Ossirene
CAS:Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.Formula:C2H4Cl3O2Te·H4NPurezza:≥98%Colore e forma:SolidPeso molecolare:312.05Aristolactam I
CAS:<p>Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway.</p>Formula:C17H11NO4Purezza:98.98% - 99.63%Colore e forma:SolidPeso molecolare:293.27Z-FA-FMK
CAS:Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.Formula:C21H23FN2O4Purezza:98.84% - 99.68%Colore e forma:SolidPeso molecolare:386.42Emricasan
CAS:Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.Formula:C26H27F4N3O7Purezza:98.13% - 99%Colore e forma:SolidPeso molecolare:569.5PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purezza:98.82%Colore e forma:SolidPeso molecolare:394.47Wedelolactone
CAS:<p>Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.</p>Formula:C16H10O7Purezza:98.07% - 99.87%Colore e forma:SolidPeso molecolare:314.25Sesamolin
CAS:Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.Formula:C20H18O7Purezza:98.77% - 99.04%Colore e forma:SolidPeso molecolare:370.35Ac-DEVD-CHO acetate
<p>Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.</p>Formula:C22H34N4O13Purezza:98.54%Colore e forma:SolidPeso molecolare:562.52
