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Ferroptosi

Ferroptosi

La ferroptosi è una forma di morte cellulare regolata caratterizzata dall'accumulo di perossidi lipidici e dallo stress ossidativo dipendente dal ferro. A differenza dell'apoptosi, la ferroptosi non è guidata dalle caspasi, ma piuttosto dal fallimento delle difese antiossidanti cellulari, che porta alla morte cellulare. Gli inibitori e gli induttori della ferroptosi sono fondamentali per studiare questa particolare via di morte cellulare, implicata in varie malattie, tra cui il cancro, la neurodegenerazione e il danno da ischemia-riperfusione. Presso CymitQuimica, offriamo una vasta gamma di modulatori della ferroptosi di alta qualità per supportare la tua ricerca sui meccanismi di morte cellulare, stress ossidativo e patologia delle malattie.

Trovati 225 prodotti di "Ferroptosi"

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  • Ciclopirox

    CAS:
    Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.
    Formula:C12H17NO2
    Purezza:97.72% - 99.78%
    Colore e forma:Solid
    Peso molecolare:207.27
  • Matrine

    CAS:
    <p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>
    Formula:C15H24N2O
    Purezza:97.16% - >99.99%
    Colore e forma:Solid
    Peso molecolare:248.36
  • Eugenol

    CAS:
    Eugenol (Allylguaiacol) is a Standardized Chemical Allergen.
    Formula:C10H12O2
    Purezza:98.03%
    Colore e forma:Colorless Or Pale Yellow Liquid Pungent Taste (Ntp 1992)
    Peso molecolare:164.20
  • L-Glutathione reduced

    CAS:
    L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals.
    Formula:C10H17N3O6S
    Purezza:97.37% - 99.99%
    Colore e forma:Solid
    Peso molecolare:307.32
  • Artesunate

    CAS:
    Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria.
    Formula:C19H28O8
    Purezza:97.67% - 99.9%
    Colore e forma:White Crystalline Powder
    Peso molecolare:384.42
  • Lovastatin

    CAS:
    Lovastatin (MK-803) is an HMG-CoA reductase inhibitor. Lovastatin lowers cholesterol and is used as a lipid-lowering agent. Cost-effective and quality-assured.
    Formula:C24H36O5
    Purezza:99.66% - 99.92%
    Colore e forma:The Substance Is A White-Yellowish To Yellow Powder Solid Powder
    Peso molecolare:404.54
  • Simvastatin

    CAS:
    Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity.
    Formula:C25H38O5
    Purezza:98.54% - 99.13%
    Colore e forma:Solid
    Peso molecolare:418.57
  • Linagliptin

    CAS:
    Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.
    Formula:C25H28N8O2
    Purezza:99.15% - >99.99%
    Colore e forma:Solid
    Peso molecolare:472.54
  • Sulfasalazine

    CAS:
    Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.
    Formula:C18H14N4O5S
    Purezza:98.00% - 99.28%
    Colore e forma:Minute Brownish-Yellow Crystals
    Peso molecolare:398.39
  • Pravastatin sodium

    CAS:
    Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.
    Formula:C23H35NaO7
    Purezza:97.14% - 99.97%
    Colore e forma:White Crystalline Powder
    Peso molecolare:446.52
  • Vildagliptin

    CAS:
    Vildagliptin (LAF237), an oral DPP-4 inhibitor with hypoglycemic effects, is metabolized and excreted in urine.
    Formula:C17H25N3O2
    Purezza:97.81% - >99.99%
    Colore e forma:White Crystalline Powder
    Peso molecolare:303.40
  • Sorafenib

    CAS:
    Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57
    Formula:C21H16ClF3N4O3
    Purezza:98% - 99.89%
    Colore e forma:Solid
    Peso molecolare:464.82
  • Curcumin

    CAS:
    Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity.
    Formula:C21H20O6
    Purezza:95% - 98.98%
    Colore e forma:Orange-Yellow Crystal Powder; Gives Brownish-Red Color With Alkali; Light-Yellow Color With Acids Physical Description Orange-Yellow Needles (Ntp 1992)
    Peso molecolare:368.38
  • Imidazole ketone erastin

    CAS:
    View and buy Imidazole ketone erastin from TargetMol.Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.Cited in 22 publications.
    Formula:C35H35ClN6O5
    Purezza:98.48% - 99.87%
    Colore e forma:Solid
    Peso molecolare:655.14
  • FSEN1

    CAS:
    FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM.
    Formula:C22H22BrN5OS
    Purezza:99.54% - 99.97%
    Colore e forma:Solid
    Peso molecolare:484.41
  • Butylated hydroxytoluene

    CAS:
    Butylated hydroxytoluene (BHT FCC/NF) is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6.
    Formula:C15H24O
    Purezza:99.72%
    Colore e forma:Colourless Solid Powder
    Peso molecolare:220.35
  • Acetylcysteine

    CAS:
    Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent.
    Formula:C5H9NO3S
    Purezza:98.01% - >99.99%
    Colore e forma:Crystals From Water Solid
    Peso molecolare:163.19
  • Fluvastatin sodium

    CAS:
    Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol
    Formula:C24H25FNNaO4
    Purezza:98.54% - 99.56%
    Colore e forma:Light Yellow Solid Powder
    Peso molecolare:433.45
  • Zileuton

    CAS:
    Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.
    Formula:C11H12N2O2S
    Purezza:98.72% - 99.43%
    Colore e forma:Crystalline Solid
    Peso molecolare:236.29
  • L-Glutamic Acid

    CAS:
    Formula:C5H9NO4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:147.1293

    Ref: IN-DA00378M

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