Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2442 prodotti di "Cromatina/Epigenetica"
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Momelotinib
CAS:Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.Formula:C23H22N6O2Purezza:97.07% - 99.56%Colore e forma:SolidPeso molecolare:414.46Ref: TM-T1849
1mg38,00€2mg49,00€5mg81,00€10mg95,00€25mg166,00€50mg259,00€100mg406,00€200mg625,00€1mL*10mM (DMSO)88,00€DL-α-Hydroxyglutaric acid disodium salt
CAS:DL-α-Hydroxyglutaric acid disodium salt (disodium 2-hydroxypentanedioate) is an α -hydroxyacid formed from the hydrolysis of (R) -5-oxy-2-tetrahydrofuranFormula:C5H6Na2O5Purezza:≥98%Colore e forma:SolidPeso molecolare:192.08SGC707
CAS:SGC707 is a potent, selective, and cell-active allosteric inhibitor of PRMT3.Formula:C16H18N4O2Purezza:99.75% - 99.89%Colore e forma:SolidPeso molecolare:298.34BIX-01294
CAS:BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).Formula:C28H38N6O2Purezza:98.58% - 99.64%Colore e forma:SolidPeso molecolare:490.64Ref: TM-T7697
1mg40,00€5mg85,00€10mg117,00€25mg207,00€50mg311,00€100mg472,00€200mg642,00€1mL*10mM (DMSO)131,00€I-CBP112
CAS:I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.Formula:C27H36N2O5Purezza:98.18%Colore e forma:SolidPeso molecolare:468.59Ref: TM-T3969
1mg34,00€2mg52,00€5mg97,00€10mg170,00€25mg313,00€50mg449,00€100mg615,00€200mg830,00€1mL*10mM (DMSO)97,00€BI-7273
CAS:BI-7273 is an effective, specific, BRD9 BD Inhibitor, which can infiltrate cell.Formula:C20H23N3O3Purezza:97.37% - 99.57%Colore e forma:SolidPeso molecolare:353.41Rucaparib monocamsylate
CAS:<p>Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.</p>Formula:C29H34FN3O5SPurezza:99.82%Colore e forma:SolidPeso molecolare:555.66BAZ1A-IN-1
CAS:BAZ1A-IN-1, a potent inhibitor, KD 0.52 μM against BAZ1A, is effective in high-BAZ1A cancer cells, not in low-BAZ1A ones.Formula:C16H12N4O3SPurezza:99.87%Colore e forma:SolidPeso molecolare:340.36Ref: TM-T9552
1mg88,00€5mg187,00€10mg283,00€25mg567,00€50mg848,00€100mg1.159,00€200mg1.549,00€1mL*10mM (DMSO)207,00€AG490
CAS:AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.Formula:C17H14N2O3Purezza:98.6% - 99.85%Colore e forma:Yellow SolidPeso molecolare:294.3Amifostine sodium
CAS:Amifostine sodium is a phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.Formula:C5H15N2NaO3PSColore e forma:SolidPeso molecolare:237.21TCS PIM-1 1
CAS:TCS PIM-1 1 (SC 204330) is a potent ATP-competitive inhibitor of Pim-1 kinase with an IC50 of 50 nM, selective over MEK1/2 and Pim-2.Formula:C18H11BrN2O2Purezza:97% - 97.98%Colore e forma:SolidPeso molecolare:367.2Ref: TM-T2253
1mg35,00€5mg64,00€10mg88,00€25mg187,00€50mg284,00€100mg424,00€200mg612,00€1mL*10mM (DMSO)97,00€PIN1 inhibitor API-1
CAS:API-1 is a Pin1 inhibitor (IC50: 72.3 nM), enhancing anticancer miRNA biogenesis and inhibiting hepatocellular carcinoma.Formula:C15H13F3N6O2Purezza:98.48%Colore e forma:SolidPeso molecolare:366.3Ref: TM-T16538
1mg60,00€5mg127,00€10mg235,00€25mg344,00€50mg512,00€100mg645,00€200mg898,00€500mg1.311,00€1mL*10mM (DMSO)140,00€TP-064
CAS:TP-064: Potent, selective PRMT4 inhibitor, IC50 < 10nM for H3 methylation, 100x selectivity, blocks MED12 methylation at 43nM.Formula:C28H34N4O2Purezza:97.85%Colore e forma:SolidPeso molecolare:458.6Ref: TM-T28996
1mg38,00€2mg49,00€5mg79,00€10mg119,00€25mg245,00€50mg487,00€100mg710,00€1mL*10mM (DMSO)80,00€OG-L002
CAS:OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.Formula:C15H15NOPurezza:97.05% - 98.62%Colore e forma:SolidPeso molecolare:225.29Danusertib
CAS:<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Formula:C26H30N6O3Purezza:97.88% - 98.79%Colore e forma:White PowderPeso molecolare:474.55CPI-455
CAS:<p>CPI-455 is a specific KDM5 inhibitor.</p>Formula:C16H14N4OPurezza:97.87% - 99.03%Colore e forma:SolidPeso molecolare:278.31Amodiaquine hydrochloride
CAS:Amodiaquine dihydrochloride: 4-aminoquinoline antimalarial, histamine N-methyltransferase inhibitor (Ki 18.6 nM), Nurr1 agonist, anti-inflammatory.Formula:C20H24Cl3N3OColore e forma:SolidPeso molecolare:428.78UNC 669
CAS:UNC 669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.Formula:C15H20BrN3OPurezza:97.38%Colore e forma:SolidPeso molecolare:338.24A-769662
CAS:A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).Formula:C20H12N2O3SPurezza:97.52% - 99.58%Colore e forma:SolidPeso molecolare:360.39Ref: TM-T2468
2mg39,00€5mg57,00€10mg79,00€25mg142,00€50mg256,00€100mg465,00€500mg1.017,00€1mL*10mM (DMSO)59,00€MS436
CAS:MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.Formula:C18H17N5O3SPurezza:97.95% - 98.92%Colore e forma:SolidPeso molecolare:383.42Ref: TM-T1854
2mg44,00€5mg65,00€10mg90,00€25mg175,00€50mg283,00€100mg452,00€200mg648,00€1mL*10mM (DMSO)72,00€JNJ-7706621
CAS:<p>JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.</p>Formula:C15H12F2N6O3SPurezza:99.1% - 99.85%Colore e forma:SolidPeso molecolare:394.36MM-102 TFA
CAS:MM-102 TFA is a potent WDR5/MLL inhibitor with IC50 of 2.4 nM; it disrupts MLL1-WDR5 interaction, impeding H3K4 HMT activity.Formula:C37H50F5N7O6Purezza:99.4% - 99.78%Colore e forma:SolidPeso molecolare:783.83Ref: TM-T8768
1mg39,00€2mg51,00€5mg105,00€10mg168,00€25mg284,00€50mg420,00€100mg620,00€1mL*10mM (DMSO)149,00€G007-LK
CAS:<p>G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.</p>Formula:C25H16ClN7O3SPurezza:97.63% - 98.17%Colore e forma:SolidPeso molecolare:529.96ASP4132
CAS:ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity.Formula:C46H51F3N6O8S2Purezza:98.34%Colore e forma:SolidPeso molecolare:937.06Ref: TM-T8432
1mg52,00€5mg120,00€10mg187,00€25mg339,00€50mg509,00€100mg715,00€200mg979,00€1mL*10mM (DMSO)195,00€MPT0G211 mesylate
CAS:MPT0G211 mesylate: potent, selective HDAC6 inhibitor (IC50=0.291nM), oral, BBB-penetrating, anti-tau and metastasis, potential anticancer.Formula:C18H19N3O5SColore e forma:SolidPeso molecolare:389.43Filgotinib
CAS:Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.Formula:C21H23N5O3SPurezza:98.03% - ≥95%Colore e forma:SolidPeso molecolare:425.5DR2313
CAS:DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.Formula:C8H10N2OSPurezza:98.65%Colore e forma:SolidPeso molecolare:182.24RGB-286638 free base
CAS:RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Formula:C29H35N7O4Purezza:98% - 99.91%Colore e forma:SolidPeso molecolare:545.63PHD-1-IN-1
CAS:PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM).Formula:C13H8N4Purezza:99.74%Colore e forma:SolidPeso molecolare:220.23Ref: TM-T9627
1mg44,00€5mg96,00€10mg139,00€25mg245,00€50mg368,00€100mg552,00€200mg748,00€1mL*10mM (DMSO)96,00€Pacritinib
CAS:Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).Formula:C28H32N4O3Purezza:99.25% - 99.49%Colore e forma:SolidPeso molecolare:472.58CPI203
CAS:CPI203 (CPI 203) is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).Formula:C19H18ClN5OSPurezza:99.13% - 99.77%Colore e forma:SolidPeso molecolare:399.9ZM-447439
CAS:ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.Formula:C29H31N5O4Purezza:99.11% - 99.59%Colore e forma:Pale Yellow SolidPeso molecolare:513.59JQKD82
CAS:JQKD82 is a selective inhibitor of KDM5 and increases H3K4me3. JQKD82 can be used in studies about the treatment of multiple myeloma.Formula:C27H40N4O5Purezza:100.00%Colore e forma:SolidPeso molecolare:500.63AZ6102
CAS:AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.Formula:C25H28N6OPurezza:97.98% - 99.91%Colore e forma:SolidPeso molecolare:428.53Bisindolylmaleimide IV
CAS:<p>Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)</p>Formula:C20H13N3O2Purezza:98.83%Colore e forma:Dark Red SolidPeso molecolare:327.34CBP/EP300-IN-1
CAS:<p>CBP/EP300-IN-1 is a CBP/EP300 bromodomain inhibitor.</p>Formula:C23H23FN2O5Purezza:99.05%Colore e forma:SolidPeso molecolare:426.44Ref: TM-T6S0071
2mg35,00€5mg52,00€10mg88,00€25mg160,00€50mg235,00€100mg354,00€200mg520,00€1mL*10mM (DMSO)86,00€OAC1
CAS:OAC1 (BAS 00287861) activates Oct4, boosts iPSC efficiency, and speeds up reprogramming.Formula:C14H11N3OPurezza:99.49% - 99.65%Colore e forma:SolidPeso molecolare:237.26Ref: TM-T2040
1mg37,00€2mg49,00€5mg70,00€10mg97,00€25mg167,00€50mg316,00€100mg570,00€1mL*10mM (DMSO)70,00€I-BRD9
CAS:I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.Formula:C22H22F3N3O3S2Purezza:98.16% - 99.51%Colore e forma:SolidPeso molecolare:497.55Ref: TM-T6859
1mg40,00€2mg51,00€5mg74,00€10mg113,00€25mg215,00€50mg411,00€100mg610,00€1mL*10mM (DMSO)84,00€Decernotinib
CAS:Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.Formula:C18H19F3N6OPurezza:99.28% - >99.99%Colore e forma:SolidPeso molecolare:392.38Ref: TM-T2636
1mg35,00€2mg50,00€5mg74,00€10mg104,00€25mg207,00€50mg311,00€100mg472,00€1mL*10mM (DMSO)84,00€OF-1
CAS:OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain.Formula:C17H18BrN3O4SPurezza:98.55% - ≥95%Colore e forma:SolidPeso molecolare:440.31Ref: TM-T2127
1mg38,00€5mg79,00€10mg130,00€25mg254,00€50mg406,00€100mg628,00€200mg879,00€1mL*10mM (DMSO)79,00€JMJD7-IN-1
CAS:<p>JMJD7-IN-1 (Benzoic acid, 2,4-dichloro-, 5-nitro-8-quinolinyl ester) is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM.</p>Formula:C16H8Cl2N2O4Purezza:99.66%Colore e forma:SolidPeso molecolare:363.15SGC-SMARCA-BRDVIII
CAS:SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM,Formula:C19H25N5O3Purezza:99.54% - 99.92%Colore e forma:SolidPeso molecolare:371.43Ref: TM-T9568
1mg47,00€5mg70,00€10mg106,00€25mg235,00€50mg376,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)57,00€Pim1/AKK1-IN-1
CAS:<p>Pim1/AKK1-IN-1: LKB1/AAK1 inhibitor with Kd 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1, also targets MPSK1, TNIK.</p>Formula:C20H13N5OPurezza:97.03% - 98.69%Colore e forma:SolidPeso molecolare:339.35BEBT-908
CAS:BEBT-908 (PI3Kα inhibitor 1) is a selective PI3Kα inhibitor (IC50 <0.1 μM). BEBT-908 also inhibits HDAC (0.1 μM≤IC50≤1 μM).Formula:C23H25N9O3SPurezza:99.67%Colore e forma:SolidPeso molecolare:507.57Ref: TM-T16529
1mg99,00€5mg235,00€10mg354,00€25mg593,00€50mg847,00€100mg1.121,00€200mg1.539,00€1mL*10mM (DMSO)263,00€Hispidulin
CAS:Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).Formula:C16H12O6Purezza:98.53% - 99.87%Colore e forma:SolidPeso molecolare:300.26RK-287107
CAS:RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).Formula:C22H26F2N4O2Purezza:99.64%Colore e forma:SolidPeso molecolare:416.46Delgocitinib EtOH
CAS:Delgocitinib (LEO-124249/JTE052) is a selective JAK inhibitor used for reducing skin inflammation and treating chronic dermatitis.Formula:C18H24N6O2Colore e forma:SolidPeso molecolare:356.43EED226
CAS:EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.Formula:C17H15N5O3SPurezza:98.14% - 99.33%Colore e forma:SolidPeso molecolare:369.4Iniparib
CAS:Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).Formula:C7H5IN2O3Purezza:98.93%Colore e forma:SolidPeso molecolare:292.03Ref: TM-T6224
5mg50,00€10mg77,00€25mg126,00€50mg229,00€100mg359,00€200mg570,00€500mg912,00€1mL*10mM (DMSO)55,00€WM-1119
CAS:WM-1119 is a highly potent, selective KAT6A/B inhibitorFormula:C18H13F2N3O3SPurezza:96.59% - 99.58%Colore e forma:SolidPeso molecolare:389.38O-304
CAS:O-304 is a pan-activator of AMP-activated protein kinase (AMPK).Formula:C16H11Cl2N3O2SPurezza:99.84% - ≥98%Colore e forma:SolidPeso molecolare:380.25Ref: TM-T7362
1mg66,00€2mg96,00€5mg144,00€10mg216,00€25mg432,00€50mg638,00€100mg908,00€500mg1.825,00€1mL*10mM (DMSO)159,00€dCBP-1
CAS:dCBP-1 selectively degrades p300/CBP via CRBN, killing multiple myeloma cells.Formula:C51H63F2N11O10Purezza:98.21% - 99.12%Colore e forma:SolidPeso molecolare:1028.11GSK2879552 2HCl (1401966-69-5(free base))
<p>GSK2879552 is an orally available, irreversible inhibitor of lysine specific demethylase 1 (LSD1), with potential antineoplastic activity.</p>Formula:C23H30Cl2N2O2Purezza:99.87% - ≥95%Colore e forma:SolidPeso molecolare:437.41Ref: TM-T4418
1mg59,00€2mg86,00€5mg109,00€10mg175,00€25mg293,00€50mg411,00€100mg610,00€500mg1.301,00€Succinic acid sodium
CAS:Succinic acid sodium is an orally active anxiolytic.Formula:C4H6O4·xNaColore e forma:SolidMLN8054
CAS:MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Formula:C25H15ClF2N4O2Purezza:98.07% - 98.26%Colore e forma:SolidPeso molecolare:476.86Ref: TM-T6315
1mg52,00€2mg71,00€5mg88,00€10mg127,00€25mg233,00€50mg376,00€100mg567,00€1mL*10mM (DMSO)93,00€dencichine
CAS:Dencichine (ODAP) is a neurotoxic agent and a haemostatic agent, which relates to modulation of the coagulation system, and fibrinolytic system.Formula:C5H8N2O5Purezza:99.93% - ≥95%Colore e forma:SolidPeso molecolare:176.13Ref: TM-TL0001
1mg48,00€5mg92,00€10mg160,00€25mg349,00€50mg520,00€100mg740,00€200mg1.026,00€1mL*10mM (DMSO)97,00€Bromosporine
CAS:Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.Formula:C17H20N6O4SPurezza:99.65% - 99.79%Colore e forma:SolidPeso molecolare:404.44Ref: TM-T6255
1mg47,00€2mgPrezzo su richiesta5mg87,00€10mg140,00€25mg274,00€50mg439,00€100mg702,00€200mg938,00€1mL*10mM (DMSO)97,00€MRTX-1719
CAS:<p>MRTX-1719 is a potent and selective inhibitor of the PRMT5/MTA complex with an IC50 value of <10 nM against PRMT5/MTAMTAPDELSDMA cell lines.Cost-effective and quality-assured.</p>Formula:C23H18ClFN6O2Purezza:98.27% - 99.18%Colore e forma:SolidPeso molecolare:464.88AZ505
CAS:AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 μM).Formula:C29H38Cl2N4O4Purezza:98.18%Colore e forma:SolidPeso molecolare:577.54Ref: TM-TQ0100
1mg64,00€5mg137,00€10mg188,00€25mg311,00€50mg487,00€100mg658,00€1mL*10mM (DMSO)168,00€Ruboxistaurin mesylate
CAS:Ruboxistaurin: PKC beta inhibitor, eases oxidative stress, heart issues & nephropathy in diabetic rats, halts retinal neovascularization.Formula:C29H32N4O6SPurezza:98%Colore e forma:SolidPeso molecolare:564.65PF-06409577
CAS:PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, for α1β1γ1).Formula:C19H16ClNO3Purezza:95.17% - 98.21%Colore e forma:SolidPeso molecolare:341.79Ref: TM-T4427
1mg35,00€2mg46,00€5mg66,00€10mg105,00€25mg210,00€50mg354,00€100mg567,00€200mgPrezzo su richiesta1mL*10mM (DMSO)74,00€XD14
CAS:<p>XD14 inhibits BET bromodomains with Kd: BRD4(1) 160nM, BRD2(1) 170nM, BRD3(1) 380nM, BRD3(2) 490nM, BRD2(2) 830nM, BRD4(2) 850nM.</p>Formula:C20H27N3O5SPurezza:97.46%Colore e forma:SolidPeso molecolare:421.51Pinometostat
CAS:Pinometostat (EPZ-5676) is a potent DOT1L histone methyltransferase inhibitor. Pinometostat has antitumor activity. Cost effective and quality assured.Formula:C30H42N8O3Purezza:99.19% - 99.86%Colore e forma:SolidPeso molecolare:562.714-Phenylbutyric acid
CAS:4-Phenylbutyric acid (Benzenebutyric acid) is a HDAC inhibitor and an endoplasmic reticulum stress (ERS) inhibitor. Cost-effective and quality-assured.Formula:C10H12O2Purezza:98.40% - 99.76%Colore e forma:SolidPeso molecolare:164.25,7,4'-Trimethoxyflavone
CAS:5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.Formula:C18H16O5Purezza:97.53%Colore e forma:SolidPeso molecolare:312.32GSK 690 Hydrochloride
CAS:<p>GSK 690 (Hydrochloride) is a reversible lysine specific demethylase 1 (LSD1) inhibitor with a Kd value of 9 nM and IC 50 of 37 nM.</p>Formula:C24H24ClN3OPurezza:98%Colore e forma:SolidPeso molecolare:405.92UNC1999
CAS:UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).Formula:C33H43N7O2Purezza:99.19% - >99.99%Colore e forma:SolidPeso molecolare:569.74Ref: TM-T3057
1mg35,00€2mg48,00€5mg70,00€10mg97,00€25mg170,00€50mg274,00€100mg424,00€200mg612,00€1mL*10mM (DMSO)89,00€GSK1379725A
CAS:<p>GSK1379725A is a selective BPTF ligand (Kd = 2.8 μM).</p>Formula:C23H23FN6O3Purezza:99.51%Colore e forma:SolidPeso molecolare:450.47MI-538
CAS:<p>MI-538 is an interaction between menin and MLL fusion proteins inhibitor(IC50 of 21 nM).</p>Formula:C27H25F3N8OSPurezza:99.61% - 99.8%Colore e forma:SolidPeso molecolare:566.68-CHLOROQUINAZOLIN-4(1H)-ONE
CAS:8-CHLOROQUINAZOLIN-4(1H)-ONE is inhibitor of Poly [ADP-ribose] polymerase 1 (human)Formula:C8H5ClN2OPurezza:98.79%Colore e forma:SolidPeso molecolare:180.59(R)-(-)-JQ1 Enantiomer
CAS:<p>(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)</p>Formula:C23H25ClN4O2SPurezza:99.38%Colore e forma:SolidPeso molecolare:456.99ICG001
CAS:ICG001 antagonizes Wnt signaling, binds CBP with 3 μM IC50, not p300.Formula:C33H32N4O4Purezza:99.06% - 99.95%Colore e forma:SolidPeso molecolare:548.63Ref: TM-T2237
1mg35,00€5mg70,00€10mg106,00€25mg207,00€50mg360,00€100mg558,00€500mg1.198,00€1mL*10mM (DMSO)86,00€Rucaparib hydrochloride
CAS:Rucaparib hydrochloride (AG014699) is an oral PARP inhibitor with Ki 1.4 nM for PARP1 and hinders H6PD, studied in CRPC research.Formula:C19H19ClFN3OColore e forma:SolidPeso molecolare:359.83Splitomicin
CAS:Splitomicin (1-Naphthalenepropanoic Acid) (IC50 of 60 μM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, displays a high activity in aFormula:C13H10O2Purezza:97.09% - 99.11%Colore e forma:SolidPeso molecolare:198.22Rucaparib acetate
CAS:Rucaparib acetate, an oral PARP-1, -2, -3 inhibitor (Ki 1.4 nM for PARP1), also moderately inhibits H6PD; promising for CRPC research.Formula:C21H22FN3O3Colore e forma:SolidPeso molecolare:383.423JQEZ5
CAS:JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).Formula:C30H38N8O2Purezza:98.14% - ≥98%Colore e forma:SolidPeso molecolare:542.683-TYP
CAS:<p>3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.</p>Formula:C7H6N4Purezza:99.16% - >99.99%Colore e forma:SolidPeso molecolare:146.15XMD8-92
CAS:XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).Formula:C26H30N6O3Purezza:98.21%Colore e forma:SolidPeso molecolare:474.55EB-47 dihydrochloride
CAS:EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).Formula:C24H29Cl2N9O6Colore e forma:SolidPeso molecolare:610.45Ruboxistaurin
CAS:Ruboxistaurin (LY333531) is a selective PKC beta inhibitor, Ki 2 nM, inhibits beta I/II (IC50: 4.7/5.9 nM), orally active.Formula:C28H28N4O3Colore e forma:SolidPeso molecolare:468.55SC-43
CAS:SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).Formula:C21H13ClF3N3O2Purezza:98.44%Colore e forma:SolidPeso molecolare:431.8Ethyl 3,4-dihydroxybenzoate
CAS:Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.Formula:C9H10O4Purezza:99.88%Colore e forma:White Crystal Or PowderPeso molecolare:182.17Brevilin A
CAS:Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formula:C20H26O5Purezza:99.97% - >99.99%Colore e forma:SolidPeso molecolare:346.42Ref: TM-T4672
1mg96,00€5mg215,00€10mg369,00€25mg610,00€50mg840,00€100mg1.130,00€500mg2.308,00€1mL*10mM (DMSO)235,00€MS31 trihydrochloride
MS31 trihydrochloride: a selective SPIN1 inhibitor, binds H3K4me3 (IC50: 77-243 nM), non-toxic to healthy cells.Formula:C20H30Cl3N3O2Colore e forma:SolidPeso molecolare:450.83Menin-MLL inhibitor 20
CAS:Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.Formula:C33H40N8O4Purezza:97.77%Colore e forma:SolidPeso molecolare:612.72Ref: TM-T9399
1mg40,00€5mg90,00€10mg135,00€25mg264,00€50mg390,00€100mg555,00€200mg752,00€1mL*10mM (DMSO)90,00€PLX51107
CAS:PLX51107 is a potent and selective BET inhibitor (Kds: 1.6, 2.1, 1.7, and 5 nM for BRD2-BD1, BRD3-BD1, BRD4-BD1, and BRDT-BD1).Formula:C26H22N4O3Purezza:99.75%Colore e forma:SolidPeso molecolare:438.48Ref: TM-TQ0253
1mg56,00€2mg81,00€5mg119,00€10mg188,00€25mg329,00€50mg490,00€100mg710,00€1mL*10mM (DMSO)131,00€AKBA
CAS:<p>AKBA (3-O-Acetyl-11-keto-beta-boswellic acid), a natural component from frankincense, is a novel activator of Nrf2.</p>Formula:C32H48O5Purezza:97.85% - 99.77%Colore e forma:SolidPeso molecolare:512.72PF-CBP1 hydrochloride
CAS:PF-CBP1 HCl selectively inhibits CREBBP bromodomain (IC50: 125 nM) and p300 (IC50: 363 nM).Formula:C29H37ClN4O3Purezza:97.11% - 99.02%Colore e forma:SolidPeso molecolare:525.08UMB298
CAS:UMB298 is a potent and selective CBP/P300 bromodomain inhibitor. UMB298 inhibits BRD4 with IC50 of 5193nM.Formula:C27H31ClN4O2Purezza:99.76%Colore e forma:SolidPeso molecolare:479.01Ref: TM-T9194
1mg48,00€5mg99,00€10mg158,00€25mg264,00€50mg370,00€100mg507,00€200mg657,00€1mL*10mM (DMSO)104,00€Methyl L-histidinate dihydrochloride
CAS:The inhibitory effect of Methyl L-histidinate dihydrochloride (L-Histidine methyl ester dihydrochloride) on histidine decarboxylase in Sprague-Dawley ratFormula:C7H13Cl2N3O2Purezza:99.74%Colore e forma:White To Off-White PowderPeso molecolare:242.1A-196
CAS:A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively; more than 100-fold selective overFormula:C18H16Cl2N4Purezza:99.92%Colore e forma:SolidPeso molecolare:359.25Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purezza:97.47% - 99.8%Colore e forma:SolidPeso molecolare:178.14(S)-CPI203
CAS:CPI-203 is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).Formula:C19H18ClN5OSPurezza:99.01% - 99.92%Colore e forma:SolidPeso molecolare:399.9Ref: TM-T6026
2mg35,00€5mg58,00€10mg94,00€25mg178,00€50mg284,00€100mg449,00€200mg627,00€1mL*10mM (DMSO)62,00€Abrocitinib
CAS:Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).Formula:C14H21N5O2SPurezza:99.09% - 99.91%Colore e forma:SolidPeso molecolare:323.41Ref: TM-TQ0037
1mg35,00€2mg48,00€5mg70,00€10mg111,00€25mg255,00€50mg465,00€100mg838,00€200mg1.130,00€1mL*10mM (DMSO)78,00€3-methyl-1,2,3,4-tetrahydroquinazolin-2-one
CAS:3-methyl-1,2,3,4-tetrahydroquinazolin-2-one is a inhibitor of BRD4 .Formula:C9H10N2OPurezza:99.3% - 99.64%Colore e forma:SolidPeso molecolare:162.19Ref: TM-T50006
2mg39,00€5mg55,00€10mg82,00€25mg126,00€50mg182,00€100mg273,00€500mg677,00€1mL*10mM (DMSO)59,00€Reversine
CAS:Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).Formula:C21H27N7OPurezza:98% - 99.45%Colore e forma:SolidPeso molecolare:393.49Ref: TM-T1825
1mg38,00€2mg49,00€5mg70,00€10mg88,00€25mg164,00€50mg224,00€100mg393,00€1mL*10mM (DMSO)70,00€AMPK activator 2
CAS:AMPK activator 2, a chloroformin derivative, may boost cancer treatment by enhancing AMPK and inhibiting mTOR pathways, and cancer cell growth.Formula:C13H18F3N5Purezza:99.86%Colore e forma:SolidPeso molecolare:301.31Tubacin
CAS:Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.Formula:C41H43N3O7SPurezza:97.62% - 98.75%Colore e forma:SolidPeso molecolare:721.86
