Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2490 prodotti di "Cromatina/Epigenetica"
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JW 55
CAS:JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2Formula:C25H26N2O5Purezza:99.31% - 99.76%Colore e forma:SolidPeso molecolare:434.48Ro 31-8220
CAS:Ro 31-8220: potent PKC inhibitor (IC50: 5-27 nM). Affects MAPKAP-K1b, MSK1, S6K1, GSK3β (IC50: 3-38 nM), not MKK3/4/6/7.Formula:C25H23N5O2SColore e forma:SolidPeso molecolare:457.55GSK-J1 sodium salt
CAS:GSK-J1 sodium salt is a potent inhibitor of the H3K27 histone demethylases JMJD3 and UTX.Formula:C22H22N5NaO2Colore e forma:SolidPeso molecolare:411.4408BMS-P5
CAS:BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor.Formula:C27H33ClN6O2Purezza:99.88%Colore e forma:SolidPeso molecolare:509.04Ref: TM-T22277
2mg47,00€5mg90,00€10mg143,00€25mg283,00€50mg505,00€100mg802,00€200mg1.074,00€1mL*10mM (DMSO)92,00€TG101209
CAS:TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Formula:C26H35N7O2SPurezza:99% - >99.99%Colore e forma:SolidPeso molecolare:509.67EPZ011989
CAS:EPZ011989: potent, selective oral EZH2 inhibitor, Ki < 3 nM, 15x more selective than EZH1, >3000x over other HMTases.Formula:C35H51N5O4Purezza:98% - 99.45%Colore e forma:SolidPeso molecolare:605.81SGC707
CAS:SGC707 is a potent, selective, and cell-active allosteric inhibitor of PRMT3.Formula:C16H18N4O2Purezza:99.75% - 99.89%Colore e forma:SolidPeso molecolare:298.34TIQ-A
CAS:TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.Formula:C11H7NOSPurezza:99.75%Colore e forma:SolidPeso molecolare:201.24Ref: TM-T50098
1mg50,00€5mg97,00€10mg170,00€25mg306,00€50mg437,00€100mg562,00€200mg777,00€1mL*10mM (DMSO)101,00€Niraparib
CAS:Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.Formula:C19H20N4OPurezza:98% - 99.91%Colore e forma:SolidPeso molecolare:320.39Ref: TM-T3231
5mg57,00€10mg84,00€25mg105,00€50mg137,00€100mg205,00€200mg304,00€500mg515,00€1mL*10mM (DMSO)63,00€(Z)-LFM-A13
CAS:(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.Formula:C11H8Br2N2O2Purezza:99.88%Colore e forma:SolidPeso molecolare:360GSK6853
CAS:GSK6853 is a potent, soluble, cell-active, and highly selective inhibitor of the BRPF1 bromodomain.Formula:C22H27N5O3Purezza:98.71% - 99.21%Colore e forma:SolidPeso molecolare:409.48RO495
CAS:RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assaysFormula:C17H14Cl2N6OPurezza:97.94%Colore e forma:SolidPeso molecolare:389.24Ref: TM-T22416
1mg46,00€5mg86,00€10mg126,00€25mg235,00€50mg344,00€100mg465,00€200mg625,00€1mL*10mM (DMSO)94,00€GSK046
CAS:GSK046 (iBET-BD2), potent oral BET BD2 inhibitor; IC50: BRD2 (264 nM), BRD3 (98 nM), BRD4 (49 nM), BRDT (214 nM); immunomodulatory.Formula:C23H27FN2O4Purezza:99.97%Colore e forma:SolidPeso molecolare:414.47Ref: TM-T8932
1mg57,00€5mg120,00€10mg200,00€25mg447,00€50mg715,00€100mg1.108,00€200mg1.485,00€1mL*10mM (DMSO)133,00€BMS-P5 free base
CAS:BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor.Formula:C27H32N6O2Purezza:99.88%Colore e forma:SolidPeso molecolare:472.58Amodiaquine hydrochloride
CAS:Amodiaquine dihydrochloride: 4-aminoquinoline antimalarial, histamine N-methyltransferase inhibitor (Ki 18.6 nM), Nurr1 agonist, anti-inflammatory.Formula:C20H24Cl3N3OColore e forma:SolidPeso molecolare:428.78Piribedil hydrochloride
CAS:Piribedil HCl treats Parkinson's, circulatory issues, aids cancer research; inhibits MLL1; D2/D3 agonist; α2-antagonist. EC50: 0.18 μM.Formula:C16H19ClN4O2Colore e forma:SolidPeso molecolare:334.82',3',5'-triacetyl-5-Azacytidine
CAS:2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.Formula:C14H18N4O8Purezza:98.34%Colore e forma:SolidPeso molecolare:370.31Ref: TM-T7840
2mg38,00€5mg50,00€10mg75,00€25mg122,00€50mg177,00€100mg266,00€200mg385,00€1mL*10mM (DMSO)60,00€PFI-2 hydrochloride
CAS:PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM),Formula:C23H26ClF4N3O3SPurezza:99.31% - 99.91%Colore e forma:SolidPeso molecolare:535.98Ref: TM-T4583
1mg38,00€2mg49,00€5mg80,00€10mg111,00€25mg200,00€50mg358,00€100mg523,00€500mg1.108,00€1mL*10mM (DMSO)122,00€BAY-598
CAS:BAY 598 is a potent and selective competitive inhibitor of SMYD2, exhibiting >100-fold selectivity over SMYD3, SUV420H1, and SUV420H2. Cost-effective and quality-assured.Formula:C22H20Cl2F2N6O3Purezza:99.18% - 99.78%Colore e forma:SolidPeso molecolare:525.34SNS-314 Mesylate
CAS:SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.Formula:C18H15ClN6OS2·CH4O3SPurezza:99.44% - 99.92%Colore e forma:SolidPeso molecolare:527.04MS436
CAS:MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.Formula:C18H17N5O3SPurezza:97.95% - 98.92%Colore e forma:SolidPeso molecolare:383.42Ref: TM-T1854
2mg44,00€5mg65,00€10mg90,00€25mg175,00€50mg283,00€100mg452,00€200mg648,00€1mL*10mM (DMSO)72,00€Momelotinib
CAS:Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.Formula:C23H22N6O2Purezza:97.07% - 99.56%Colore e forma:SolidPeso molecolare:414.46Ref: TM-T1849
1mg38,00€2mg49,00€5mg81,00€10mg95,00€25mg166,00€50mg259,00€100mg406,00€200mg625,00€1mL*10mM (DMSO)88,00€Deucravacitinib
CAS:Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.Formula:C20H19D3N8O3Purezza:98.52% - >99.99%Colore e forma:SolidPeso molecolare:425.46Ref: TM-T14687
1mg59,00€5mg144,00€10mg261,00€25mg410,00€50mg607,00€100mg863,00€1mL*10mM (DMSO)158,00€GSK-5959
CAS:GSK-5959 is a selective BRPF1 inhibitor with IC50 ~80 nM, 100-fold more specific than 35 other bromodomains.Formula:C22H26N4O3Purezza:98.35% - 98.65%Colore e forma:SolidPeso molecolare:394.47Daminozide
CAS:Daminozide (Succinic Acid) is a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily.Formula:C6H12N2O3Purezza:99.86%Colore e forma:White Crystalline Solid Physical Description Odorless White Crystals Or Powder (Ntp 1992)Peso molecolare:160.17KDM4D-IN-1
CAS:KDM4D-IN-1 is a KDM4D inhibitor (IC50: 0.41±0.03 μM).Formula:C11H7N5OPurezza:99.51% - >99.99%Colore e forma:SolidPeso molecolare:225.21Ref: TM-T4214
1mg77,00€5mg166,00€10mg259,00€25mg522,00€50mg838,00€100mg1.225,00€1mL*10mM (DMSO)177,00€GSK3685032
CAS:GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).
Formula:C22H24N6OSPurezza:98.56% - 99.49%Colore e forma:SolidPeso molecolare:420.53UNC6934
CAS:UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.Formula:C24H21N5O4Purezza:98.67%Colore e forma:SolidPeso molecolare:443.45Ref: TM-T9584
1mg47,00€5mg92,00€10mg152,00€25mg326,00€50mg485,00€100mg670,00€200mg888,00€1mL*10mM (DMSO)101,00€UNC0646
CAS:UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP with low cellular toxicity.Formula:C36H59N7O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:621.9Venadaparib hydrochloride
CAS:Venadaparib HCl (IDX-1197) is a potent, selective PARP inhibitor with notable anticancer effects, especially in solid tumors.Formula:C23H24ClFN4O2Colore e forma:SolidPeso molecolare:442.926-Bromo-3-methyl-1,4-dihydroquinazolin-2-one
CAS:CHEMBRDG-BB 7118966 is an inhibitor of Bromodomain-containing protein 4 (human).Formula:C9H9BrN2OPurezza:99.28%Colore e forma:SolidPeso molecolare:241.08Ref: TM-T8609
1mg62,00€5mg123,00€10mg180,00€25mg298,00€50mg419,00€100mg567,00€200mg752,00€1mL*10mM (DMSO)113,00€FL-411
CAS:FL-411 (BRD4-IN-1) is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for BRD4.Formula:C18H19N3O2SPurezza:98.19%Colore e forma:SolidPeso molecolare:341.43XD14
CAS:XD14 inhibits BET bromodomains with Kd: BRD4(1) 160nM, BRD2(1) 170nM, BRD3(1) 380nM, BRD3(2) 490nM, BRD2(2) 830nM, BRD4(2) 850nM.
Formula:C20H27N3O5SPurezza:97.46%Colore e forma:SolidPeso molecolare:421.51Aurora kinase inhibitor-3
CAS:Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,Formula:C21H18F3N5OPurezza:98.91%Colore e forma:SolidPeso molecolare:413.4Ref: TM-T5524
1mg70,00€2mg95,00€5mg160,00€10mg250,00€25mg424,00€50mg612,00€100mg842,00€200mg1.159,00€1mL*10mM (DMSO)170,00€WM-1119
CAS:WM-1119 is a highly potent, selective KAT6A/B inhibitorFormula:C18H13F2N3O3SPurezza:96.59% - 99.58%Colore e forma:SolidPeso molecolare:389.38MS7972
CAS:MS7972 is CREBBP inhibitor that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μMFormula:C14H13NO2Purezza:99.78%Colore e forma:SolidPeso molecolare:227.26Ref: TM-T8774
1mg57,00€5mg111,00€10mg183,00€25mg311,00€50mg449,00€100mg615,00€200mg830,00€1mL*10mM (DMSO)123,00€(+)-JQ1 PA
CAS:(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM).Formula:C22H20ClN5OSPurezza:98.36%Colore e forma:SolidPeso molecolare:437.95Molibresib
CAS:Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).Formula:C22H22ClN5O2Purezza:97.70% - 99.08%Colore e forma:SolidPeso molecolare:423.9Ref: TM-T1906
1mg43,00€2mg57,00€5mg93,00€10mg125,00€25mg216,00€50mg359,00€100mg535,00€200mg752,00€500mg1.169,00€1mL*10mM (DMSO)93,00€3-methyl-1,2-dihydroquinolin-2-one
CAS:3-methyl-1,2-dihydroquinolin-2-one is the first known micromolar inhibitors of the ATAD2 bromodomain.Formula:C10H9NOPurezza:99.62%Colore e forma:SolidPeso molecolare:159.18Ref: TM-T50035
1mg35,00€5mg77,00€10mg103,00€25mg170,00€50mg250,00€100mg354,00€200mg480,00€1mL*10mM (DMSO)62,00€Protosappanin A
CAS:Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.
Formula:C15H12O5Purezza:99.42% - 99.82%Colore e forma:SolidPeso molecolare:272.25E7449
CAS:E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.Formula:C18H15N5OPurezza:97.13%Colore e forma:SolidPeso molecolare:317.34Ref: TM-T4471
1mg35,00€5mg93,00€10mg120,00€25mg188,00€50mg284,00€100mg420,00€200mg622,00€1mL*10mM (DMSO)94,00€Naphthol AS-E
CAS:Naphthol AS-E (nAS-E) is an the KIX-KID interaction and CREB-mediated gene transcription inhibitor.Formula:C17H12ClNO2Purezza:99.33%Colore e forma:Grey Solid PowderPeso molecolare:297.74TCS PIM-1 1
CAS:TCS PIM-1 1 (SC 204330) is a potent ATP-competitive inhibitor of Pim-1 kinase with an IC50 of 50 nM, selective over MEK1/2 and Pim-2.Formula:C18H11BrN2O2Purezza:97% - 97.98%Colore e forma:SolidPeso molecolare:367.2Ref: TM-T2253
1mg35,00€5mg64,00€10mg88,00€25mg187,00€50mg284,00€100mg424,00€200mg612,00€1mL*10mM (DMSO)97,00€TP-3654
CAS:TP-3654 is a second-generation Pim kinase inhibitor (Ki values against Pim-1/3: 5/42 nM).Formula:C22H25F3N4OPurezza:99.8% - 99.95%Colore e forma:SolidPeso molecolare:418.46Olaparib
CAS:View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.Formula:C24H23FN4O3Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:434.46E-7386
CAS:E-7386 is an oral active CBP/ -catenin modulator.Formula:C39H48FN9O4Purezza:98.92% - 99.91%Colore e forma:SolidPeso molecolare:725.85Ref: TM-T11136
1mg87,00€2mg135,00€5mg230,00€10mg376,00€25mg647,00€50mg920,00€100mg1.225,00€1mL*10mM (DMSO)369,00€XY1
CAS:XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), It is intended to be used as a
Formula:C17H19N3O2Purezza:97.74% - 99%Colore e forma:SolidPeso molecolare:297.35RVX-297
CAS:RVX-297 selectively inhibits BD2 domains of BET bromodomains, binding preferentially to BET proteins.
Formula:C24H29N3O4Purezza:99.62%Colore e forma:SolidPeso molecolare:423.5IOX1
CAS:IOX1, a broad-spectrum 2OG oxygenase inhibitor, IC50: KDM4A - 0.6uM, KDM3A - 0.1uM.Formula:C10H7NO3Purezza:99.67%Colore e forma:SolidPeso molecolare:189.17Pacritinib hydrochloride
CAS:Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.Formula:C28H32N4O3·xClHColore e forma:SolidPeficitinib
CAS:Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.Formula:C18H22N4O2Purezza:98.67% - 99.4%Colore e forma:SolidPeso molecolare:326.39Ref: TM-T6933
2mg40,00€5mg66,00€10mg104,00€25mg182,00€50mg283,00€100mg439,00€200mg645,00€1mL*10mM (DMSO)73,00€Alobresib
CAS:Alobresib (Vorolanib) is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.Formula:C26H23N5O2Purezza:97.63%Colore e forma:SolidPeso molecolare:437.49Ref: TM-T8495
1mg73,00€2mg93,00€5mg144,00€10mg274,00€25mg535,00€50mg753,00€100mg1.035,00€1mL*10mM (DMSO)159,00€AZD5305
CAS:AZD5305 is a potent, selective and oral active PARP inhibitor.Formula:C22H26N6O2Purezza:98.68% - 99.93%Colore e forma:SolidPeso molecolare:406.48Ref: TM-T9165
1mg113,00€5mg235,00€10mg378,00€25mg630,00€50mg898,00€100mg1.216,00€1mL*10mM (DMSO)259,00€DCLX069
CAS:DCLX069: PRMT1 inhibitor, IC50=17.9µM, targets SAM pocket, inhibits breast/liver cancer, and AML cell growth.Formula:C20H25N3O2Purezza:97.76%Colore e forma:SolidPeso molecolare:339.43Ref: TM-T27133
1mg38,00€2mg49,00€5mg79,00€10mg111,00€25mg187,00€50mg305,00€100mg487,00€500mg1.035,00€1mL*10mM (DMSO)92,00€CPI-1205
CAS:CPI-1205 是一种高效的选择性 EZH2 抑制剂（IC50：0.002 μM，EC50：0.032 μM）。Formula:C27H33F3N4O3Purezza:98.71% - 99.7%Colore e forma:SolidPeso molecolare:518.57SGC2085
CAS:SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).Formula:C19H24N2O2Purezza:99.61% - 99.71%Colore e forma:SolidPeso molecolare:312.41Ref: TM-T7089
1mg88,00€2mg119,00€5mg227,00€10mg341,00€25mg563,00€50mg820,00€100mg1.130,00€1mL*10mM (DMSO)160,00€JANEX-1
CAS:JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.Formula:C16H15N3O3Purezza:98% - 99.81%Colore e forma:SolidPeso molecolare:297.31MK-8745
CAS:MK-8745 is a potent and selective Aurora A inhibitor.
Formula:C20H19ClFN5OSPurezza:99.09% - 99.79%Colore e forma:SolidPeso molecolare:431.91ZM39923 hydrochloride
CAS:ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Formula:C23H25NO·HClPurezza:98.05%Colore e forma:SolidPeso molecolare:367.91AZD5153 6-Hydroxy-2-naphthoic acid
CAS:AZD5153 6-Hydroxy-2-naphthoic acid (AZD5153) is a potent triazolopyridazine-based Bromodomain (BRD4) and Extraterminal (BET) inhibitor used in cancer treatmentsFormula:C25H33N7O3·C11H8O3Purezza:97.26% - ≥95%Colore e forma:SolidPeso molecolare:667.75dBET1
CAS:dBET1 fuses (+)-JQ1 with thalidomide, degrades BET proteins via cereblon (EC50: 430 nM), and triggers apoptosis.Formula:C38H37ClN8O7SPurezza:98.02% - 99.3%Colore e forma:SolidPeso molecolare:785.27Ref: TM-T4495
1mg52,00€5mg104,00€10mg170,00€25mg283,00€50mg452,00€100mg687,00€200mg938,00€1mL*10mM (DMSO)154,00€Piribedil
CAS:Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.Formula:C16H18N4O2Purezza:99.79% - 99.82%Colore e forma:SolidPeso molecolare:298.34SP-146
SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).Formula:C25H20FN7OPurezza:97.82%Colore e forma:SolidPeso molecolare:453.47Ref: TM-T8685
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)177,00€PIN1 inhibitor API-1
CAS:API-1 is a Pin1 inhibitor (IC50: 72.3 nM), enhancing anticancer miRNA biogenesis and inhibiting hepatocellular carcinoma.Formula:C15H13F3N6O2Purezza:98.48%Colore e forma:SolidPeso molecolare:366.3Ref: TM-T16538
1mg60,00€5mg127,00€10mg235,00€25mg344,00€50mg512,00€100mg645,00€200mg898,00€500mg1.311,00€1mL*10mM (DMSO)140,00€HIF-2α-IN-4
CAS:HIF-2a translation inhibitor is a compound used as a molecular building block.Formula:C9H9N3O4S2Purezza:≥98%Colore e forma:SolidPeso molecolare:287.32Ref: TM-T50099
5mg39,00€10mg64,00€25mg117,00€50mg212,00€100mg316,00€200mg454,00€1mL*10mM (DMSO)47,00€Nicotinamide Hydrochloride
CAS:Nicotinamide Hydrochloride, a vitamin B3 form, inhibits SIRT2 and melanoma growth, enhancing NAD+, ATP, ROS, and survival in melanoma mice.Formula:C6H7ClN2OColore e forma:SolidPeso molecolare:158.59PJ34
CAS:PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.
Formula:C17H17N3O2Purezza:95.05% - 99.85%Colore e forma:SolidPeso molecolare:295.34Gusacitinib HCl
CAS:Gusacitinib (ASN-002/EN-3351), a potent SYK/JAK inhibitor, has strong antitumor activity in various cancers.Formula:C24H29ClN8O2Colore e forma:SolidPeso molecolare:497Glucosamine sulfate
CAS:Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.Formula:C6H13NO5·H2SO4Purezza:99.64%Colore e forma:White CrystalPeso molecolare:277.25GSK121
CAS:GSK121 is an inhibitor of selective PAD4.
Formula:C25H26F3N5O3Purezza:98.92%Colore e forma:SolidPeso molecolare:501.51MS023
CAS:MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8,Formula:C17H25N3OPurezza:98.31% - 99.87%Colore e forma:SolidPeso molecolare:287.4Ref: TM-T6900
1mg39,00€2mg51,00€5mg88,00€10mg119,00€25mg243,00€50mg378,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)84,00€TCS-PIM-1-4a
CAS:SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).Formula:C11H6F3NO2SPurezza:99.89%Colore e forma:SolidPeso molecolare:273.23MS049
CAS:MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC 50 of 34 nM and 43 nM, respectively.Formula:C15H24N2OPurezza:98.91%Colore e forma:SolidPeso molecolare:248.36Ref: TM-T4378
2mg35,00€5mg51,00€10mg85,00€25mg158,00€50mg235,00€100mg354,00€200mg520,00€1mL*10mM (DMSO)55,00€Picolinamide
CAS:Picolinamide (Picolinoylamide) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.Formula:C6H6N2OPurezza:99.6%Colore e forma:SolidPeso molecolare:122.12SETDB1-TTD-IN-1 TFA
SETDB1-TTD-IN-1 TFA: potent, selective SETDB1-TTD inhibitor (Kd: 88 nM), useful for related biological research.Formula:C30H32F3N5O4Colore e forma:SolidPeso molecolare:583.6NMS-P118
CAS:NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.
Formula:C20H24F3N3O2Purezza:98.79%Colore e forma:SolidPeso molecolare:395.42SGI-1776
CAS:SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.Formula:C20H22F3N5OPurezza:99.3% - >99.99%Colore e forma:SolidPeso molecolare:405.42GSK1324726A
CAS:GSK1324726A (I-BET726) is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).
Formula:C25H23ClN2O3Purezza:98.34% - 99.85%Colore e forma:SolidPeso molecolare:434.91HDAC-IN-7
CAS:HDAC-IN-7 (HBI-8000) (Chidamide impurity) is an impurity of Chidamide.Formula:C22H19FN4O2Purezza:97.64% - 98.45%Colore e forma:SolidPeso molecolare:390.41Ref: TM-T2025
1mg58,00€2mg82,00€5mg130,00€10mg215,00€25mg429,00€50mg628,00€100mg893,00€1mL*10mM (DMSO)111,00€NKL 22
CAS:NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.Formula:C19H23N3O2Purezza:96.16% - 96.24%Colore e forma:SolidPeso molecolare:325.4CXD101
CAS:CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class IIFormula:C24H29N5OPurezza:99.82%Colore e forma:SolidPeso molecolare:403.52MI-538
CAS:MI-538 is an interaction between menin and MLL fusion proteins inhibitor(IC50 of 21 nM).
Formula:C27H25F3N8OSPurezza:99.61% - 99.8%Colore e forma:SolidPeso molecolare:566.65,7,4'-Trimethoxyflavone
CAS:5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.Formula:C18H16O5Purezza:97.53%Colore e forma:SolidPeso molecolare:312.32GSK 690 Hydrochloride
CAS:GSK 690 (Hydrochloride) is a reversible lysine specific demethylase 1 (LSD1) inhibitor with a Kd value of 9 nM and IC 50 of 37 nM.Formula:C24H24ClN3OPurezza:98%Colore e forma:SolidPeso molecolare:405.92dCBP-1
CAS:dCBP-1 selectively degrades p300/CBP via CRBN, killing multiple myeloma cells.Formula:C51H63F2N11O10Purezza:98.21% - 99.12%Colore e forma:SolidPeso molecolare:1028.11Succinic acid sodium
CAS:Succinic acid sodium is an orally active anxiolytic.Formula:C4H6O4·xNaColore e forma:Solid2-hexyl-4-Pentynoic Acid
CAS:2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.Formula:C11H18O2Purezza:98%Colore e forma:SolidPeso molecolare:182.26ITSA-1
CAS:ITSA-1 is membrane permeable and specifically suppresses TSA inhibition of HDAC (histone deacetylase), but shows no activity towards other HDAC inhibitors.Formula:C13H7Cl2N3OPurezza:99.78% - 99.89%Colore e forma:SolidPeso molecolare:292.12Ref: TM-T3358
10mg34,00€25mg66,00€50mg90,00€100mg152,00€200mg219,00€500mg358,00€1mL*10mM (DMSO)54,00€WH-4-025
CAS:WH-4-025 is a Salt-inducible kinase (SIK) inhibitor.Formula:C39H38F3N7O5Purezza:99.41%Colore e forma:SolidPeso molecolare:741.76Ref: TM-T9219
1mg40,00€2mg52,00€5mg88,00€10mg137,00€25mg264,00€50mg419,00€100mg617,00€1mL*10mM (DMSO)87,00€XL019
CAS:XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.Formula:C25H28N6O2Purezza:99.19%Colore e forma:SolidPeso molecolare:444.53Ref: TM-T3072
2mg46,00€5mg66,00€10mg97,00€25mg159,00€50mg226,00€100mg339,00€200mg502,00€1mL*10mM (DMSO)82,00€BI-9564
CAS:BI-9564, a specific cell-permeable BRD9 BD inhibitor. The Kd for BRD9 is 5.9 nM, and IC50 for BET family is > 100 μM.
Formula:C20H23N3O3Purezza:99.38%Colore e forma:SolidPeso molecolare:353.41LMK-235
CAS:LMK-235 is a potent HDAC inhibitor, and is used in cancer research.Formula:C15H22N2O4Purezza:98.18% - 99.68%Colore e forma:SolidPeso molecolare:294.35Ref: TM-T6061
5mg52,00€10mg74,00€25mg132,00€50mg222,00€100mg403,00€200mg593,00€500mg888,00€1mL*10mM (DMSO)49,00€AK-1
CAS:AK-1: SIRT2 inhibitor, IC50 12.5 μM, hinders Alzheimer's neurodegeneration, arrests colon cancer cell cycle.Formula:C19H21N3O5SPurezza:98.32% - 99.44%Colore e forma:SolidPeso molecolare:403.45RGFP966
CAS:RGFP966 is an HDAC3 inhibitor (IC50: 0.08 μM) and does not affect other HDACs at concentrations up to 15 μM.Formula:C21H19FN4OPurezza:99.2% - 99.88%Colore e forma:SolidPeso molecolare:362.4Ref: TM-T1762
1mg34,00€2mg49,00€5mg74,00€10mg99,00€25mg160,00€50mg245,00€100mg356,00€1mL*10mM (DMSO)82,00€ORY1001
CAS:ORY1001: Oral LSD1/KDM1A inhibitor, highly selective, IC50 <20 nM.Formula:C15H22N2·2HClPurezza:99.85% - 99.96%Colore e forma:SolidPeso molecolare:303.27Ref: TM-T6922
1mg59,00€2mg84,00€5mg134,00€10mg234,00€25mg452,00€50mg660,00€100mg939,00€500mg1.882,00€1mL*10mM (DMSO)134,00€CYC-116
CAS:CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not activeFormula:C18H20N6OSPurezza:97.36% - 97.59%Colore e forma:SolidPeso molecolare:368.46M344
CAS:M344 (Histone Deacetylase Inhibitor III) is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation.Formula:C16H25N3O3Purezza:98.18%Colore e forma:SolidPeso molecolare:307.39Tucidinostat
CAS:Tucidinostat is an oral HDAC1/2/3/10 inhibitor (IC50: 67-160 nM), weaker on HDAC8/11, inactive on HDAC4/5/6/7/9.Formula:C22H19FN4O2Purezza:97.01% - 99.95%Colore e forma:SolidPeso molecolare:390.41Ref: TM-T4481
5mg60,00€10mg95,00€25mg159,00€50mg250,00€100mg399,00€200mg558,00€500mg832,00€1mL*10mM (DMSO)60,00€Thiomyristoyl
CAS:Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.Formula:C34H51N3O3SPurezza:99.16%Colore e forma:SolidPeso molecolare:581.85Ref: TM-T3447
1mg54,00€2mg73,00€5mg92,00€10mg117,00€25mg215,00€50mg360,00€100mg537,00€1mL*10mM (DMSO)117,00€Remetinostat
CAS:Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cellFormula:C16H21NO6Purezza:98.67%Colore e forma:SolidPeso molecolare:323.34
