Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2442 prodotti di "Cromatina/Epigenetica"
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Bizine
CAS:Bizine, a Phenelzine analogue, selectively inhibits LSD1 (Ki=59 nM), modulates histone methylation in cancer, and may have neuroprotective uses.Formula:C18H23N3OColore e forma:SolidPeso molecolare:297.39SIRT1-IN-2
CAS:SIRT1-IN-2 (compound 3h) is a potent and selective inhibitor of SIRT1 (silent information regulator 1) with an IC 50 of 1.6 μM [1].Formula:C13H15ClN2OColore e forma:SolidPeso molecolare:250.72(2R/S)-6-PNG
CAS:(2R/S)-6-PNG (6-Prenylnaringenin) from hops is a natural histone deacetylase inhibitor that blocks T-type calcium channels reducing neurogenicity in mice.Formula:C20H20O5Purezza:98%Colore e forma:SolidPeso molecolare:340.37MIV-6
CAS:MIV-6 is an inhibitor of the menin-mixed lineage leukemia interaction.Formula:C27H35N3OColore e forma:SolidPeso molecolare:417.59EPZ032597
CAS:EPZ032597 is a novel selective inhibitor of SMYD2 with an IC50 of 16 nM. EPZ032597 has anticancer activity and prevent and treat pancreatic cancerFormula:C20H23N7OPurezza:99.70%Colore e forma:SolidPeso molecolare:377.44TM6089
CAS:TM6089 is an inhibitor of Prolyl Hydroxylase that stimulates HIF activity without iron chelation, induces angiogenesis, and protects organ against ischemia.Formula:C13H14N4O3SPurezza:99.70%Colore e forma:SolidPeso molecolare:306.34Ref: TM-T17105
1mg52,00€5mg115,00€10mg167,00€25mg301,00€50mg452,00€100mg658,00€200mg884,00€1mL*10mM (DMSO)123,00€JAK-IN-28
CAS:JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of cancer and inflammatory diseases [1].Formula:C20H18ClN7OPurezza:98%Colore e forma:SolidPeso molecolare:407.86JAK-IN-30
CAS:JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with half-maximal inhibitory concentration (IC50Formula:C19H26N8SPurezza:98%Colore e forma:SolidPeso molecolare:398.53Eleven-Nineteen-Leukemia Protein IN-1
CAS:ENL-IN-1: Potent ENL YEATS domain inhibitor with 14.5 nM IC50, enhances thermal stability in vitro.Formula:C27H33N7O2Purezza:98%Colore e forma:SolidPeso molecolare:487.6IDO1 and HDAC1 Inhibitor
CAS:IDO1 and HDAC1 Inhibitor is a dual IDO1 and HDAC1 inhibitor (IC50s: 69.0 nM and 66.5 nM).Formula:C25H22BrFN8O4Purezza:98%Colore e forma:SolidPeso molecolare:597.4HDAC-IN-49
HDAC-IN-49: potent, broad HDAC inhibitor; IC50s: 10-1880 nM for HDAC1-6; strong anti-leukemic, low toxicity to healthy cells.Formula:C26H27FN4O4Colore e forma:SolidPeso molecolare:478.52Angiogenesis agent 1
CAS:Compound C-31, a salidroside-based glycoside, activates HIF-1α and may aid in diabetic limb ischemia studies.Formula:C20H24O7Purezza:98%Colore e forma:SolidPeso molecolare:376.4Sirt1/2-IN-1
CAS:Sirt1/2-IN-1 inhibits SIRT1 (IC50: 1.81 μg/mL) and SIRT2 (2.10 μg/mL), less on SIRT3 (20.5 μg/mL), with anticancer properties.Formula:C22H13ClN2OS2Colore e forma:SolidPeso molecolare:420.93BET bromodomain inhibitor 3
CAS:BET Bromodomain Inhibitor 3 is a BET bromodomain inhibitor with an inhibitory Ki value of >40 µM against BrdT.Formula:C18H17N3O4Purezza:98%Colore e forma:SolidPeso molecolare:339.35PF-07899895
CAS:PF-07899895 (compound 34) is a potent SIK (salt-induced kinase) inhibitor with IC50 values of 1.2/0.9/1.8 nM for SIK1/SIK2/SIK3.Formula:C23H23N5OSPeso molecolare:417.53Ref: TM-T200199
1mg464,00€5mgPrezzo su richiesta10mgPrezzo su richiesta25mg3.372,00€50mgPrezzo su richiestaPIM-1 Inhibitor 2
CAS:PIM-1 Inhibitor 2 (PIM1-IN-2) is a potent Pim-1 inhibitor with potential anti-cancer activity, used in cancer research.Formula:C17H11ClN4OPurezza:98.81%Colore e forma:SolidPeso molecolare:322.75PRMT4-IN-1
CAS:PRMT4-IN-1 is a selective inhibitor of PRMT4, demonstrating an IC50 value of 3.2 nM, and has been shown to reduce the relative viability of MCF7 cells [1].Formula:C23H28FN3OPurezza:98%Colore e forma:SolidPeso molecolare:381.49LP99
CAS:LP99 is an epigenetic probe.Formula:C26H30ClN3O4SPurezza:99.74%Colore e forma:SolidPeso molecolare:516.05Ref: TM-T15784
1mg43,00€5mg96,00€10mg145,00€25mg305,00€50mg442,00€100mgPrezzo su richiesta1mL*10mM (DMSO)97,00€CX-6258
CAS:CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good biological activity and kinase specificity.Formula:C26H24ClN3O3Purezza:97.46%Colore e forma:SolidPeso molecolare:461.94Ref: TM-T1834
1mg37,00€5mg80,00€10mg106,00€25mg208,00€50mg311,00€100mg472,00€200mg658,00€1mL*10mM (DMSO)81,00€DC_C66
CAS:DC_C66 selectively inhibits CARM1 with IC50 of 1.8μM; also affects PRMT1, 6, 5. It's cell-permeable.Formula:C28H22NO2Purezza:98%Colore e forma:SolidPeso molecolare:404.48HDAC-IN-43
CAS:HDAC-IN-43: potent HDAC 1/3/6 inhibitor (IC50: 82 nM HDAC1, 45 nM HDAC3, 24 nM HDAC6); weak PI3K/mTOR (IC50: 3.6μM, 3.7μM); anti-proliferative.Formula:C22H28N6O4Colore e forma:SolidPeso molecolare:440.5BET-IN-2
CAS:BET-IN-2 is a BET inhibitor (IC50: 52 nM for BRD4-BD1).Formula:C23H29N3OPurezza:98%Colore e forma:SolidPeso molecolare:363.5Tripolin A
CAS:<p>Tripolin A is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5 μM and 7 μM, respectively)</p>Formula:C15H11NO3Purezza:98%Colore e forma:SolidPeso molecolare:253.25TNKS-IN-41
CAS:TNKS-IN-41 highly potent and selective inhibitor of tankyrase.Formula:C24H22N10O2Purezza:98%Colore e forma:SolidPeso molecolare:482.5UMB-136
CAS:UMB-136 is a bromodomain BRD4 inhibitor that acts by significantly inducing HIV-1 reactivation.Formula:C24H27N5O2Purezza:98%Colore e forma:SolidPeso molecolare:417.5CM-579
CAS:CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells.Formula:C29H40N4O3Purezza:99.23%Colore e forma:SolidPeso molecolare:492.65Ref: TM-T10840L
1mg55,00€5mg96,00€10mg138,00€25mg217,00€50mg319,00€100mg472,00€1mL*10mM (DMSO)124,00€2′-Deoxy-5-nitrocytidine
CAS:2′-Deoxy-5-nitrocytidine is a DNA Methyltransferase inhibitor that can be used for cancer research[1].Formula:C9H12N4O6Colore e forma:SolidPeso molecolare:272.21SB-284851-BT
CAS:SB-284851-BT: BRD4/p38α/BRDT inhibitor; IC50: BRD4-BD1 1.7µM, BRDT 18µM, BRD4 3.7µM; Kd p38α 0.47nM; reduces IL-8, affects c-Myc/NF-κB.Formula:C26H26FN5OColore e forma:SolidPeso molecolare:443.52PKC-IN-4
CAS:PKC-IN-4 (compound 7l) is a highly potent and orally active inhibitor of atypical protein kinase C (aPKC), exhibiting an IC 50 value of 0.52 μM.Formula:C21H25N5SColore e forma:SolidPeso molecolare:379.52CD161
CAS:CD161: powerful, selective oral BET inhibitor; IC50: 28.2 nM (BRD4 BD1), 7.2 nM (BRD4 BD2); strong anticancer properties.Formula:C26H21N5O2Purezza:98%Colore e forma:SolidPeso molecolare:435.48LSD1-IN-5
CAS:LSD1-IN-5, a reversible LSD1 inhibitor, boosts H3K4me2 without affecting LSD1 expression; IC50: 121 nM.Formula:C15H13BrN2O3Purezza:98%Colore e forma:SolidPeso molecolare:349.18YF479
CAS:YF479 is an inhibitor of histone deacetylase that acts by inhibiting breast tumor growth, metastasis, and recurrence.Formula:C22H27BrN2O5Purezza:98%Colore e forma:SolidPeso molecolare:479.36DC-CPin7
CAS:DC-CPin7, a powerful inhibitor of the bromodomain of CREB-binding protein (CBP), exhibits an IC50 value of 2.5 μM [1].Formula:C19H22N2O5Colore e forma:SolidPeso molecolare:358.39OICR-0547
CAS:OICR-0547 is an inactive derivative of OICR-9429 and is commonly used as a negative control for OICR-9429.Formula:C28H29F3N4O4Purezza:98%Colore e forma:SolidPeso molecolare:542.55HIF-1α inhibitor-1
CAS:HIF-1α inhibitor-1 is a HIF-1 alpha inhibitor.Formula:C15H11N3O4Colore e forma:SolidPeso molecolare:297.27SYK/JAK-IN-1
CAS:SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2.Formula:C24H26N8O3Colore e forma:SolidPeso molecolare:474.52Bisindolylmaleimide II
CAS:protein kinase C (PKC) inhibitorFormula:C27H26N4O2Purezza:98%Colore e forma:SolidPeso molecolare:438.52LSD1-IN-12
CAS:LSD1-IN-12 (compound 2) is an effective inhibitor of LSD1, demonstrating inhibitory Ki values of 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), and 3.5 μM (MAO-BFormula:C16H16N2OColore e forma:SolidPeso molecolare:252.31SRTCX1002
CAS:SRTCX1002 is a SIRT1 Activator Suppressing Inflammatory Responses through Promotion of p65 Deacetylation and NF-κB Activity inhibitor.Formula:C21H19N5O2SPurezza:98%Colore e forma:SolidPeso molecolare:405.47KDM5-C49
CAS:KDM5-C49 is a potent and selective inhibitor of KDM5, which regulates cell proliferation and stem cell self-renewal and differentiation.Formula:C15H24N4O3Purezza:98%Colore e forma:SolidPeso molecolare:308.38SIRT1-IN-3
CAS:SIRT1-IN-3 (compound 3j) is a potent and selective inhibitor of silent information regulator 1 (SIRT1) with an IC 50 of 4.2 μM [1].Formula:C13H15BrN2OColore e forma:SolidPeso molecolare:295.17PU141
CAS:PU141 is a novel inhibitor of histone acetyltransferase (HAT).Formula:C14H9F3N2OSPurezza:98%Colore e forma:SolidPeso molecolare:310.29CHIC35
CAS:CHIC-35 is a selective deacetylase SIRT1 inhibitor.Formula:C14H15ClN2OColore e forma:SolidPeso molecolare:262.73ZYJ-34c
CAS:ZYJ-34c is a potent oral antitumor activities histone deacetylase inhibitor (HDACi).Formula:C31H42N4O7Purezza:98%Colore e forma:SolidPeso molecolare:582.69OTS186935 trihydrochloride
CAS:OTS186935 trihydrochloride is a protein methyltransferase inhibitor of SUV39H2(IC50 of 6.49 nM).Formula:C25H29Cl4N5O2Purezza:98%Colore e forma:SolidPeso molecolare:573.34GSK360A
CAS:GSK360A is a novel prolyl hydroxylase (PHD) domain-containing enzyme inhibitor.Formula:C17H17FN2O5Purezza:98%Colore e forma:SolidPeso molecolare:348.33Valemetostat tosylate
CAS:Valemetostat tosylate is a dual inhibitor of EZH1/2 and used in the research of relapsed/refractory peripheral T-cell lymphoma.Formula:C33H42ClN3O7SPurezza:98%Colore e forma:SolidPeso molecolare:660.22ET-JQ1-OH
CAS:ET-JQ1-OH is an allele-specific BET inhibitor.Formula:C21H21ClN4O2SColore e forma:SolidPeso molecolare:428.93KP-302
CAS:<p>KP-302 is a selective PAD inhibitor, reversing physical disability in multiple sclerosis (MS) mice and clearing T-cell infiltration in the brain.</p>Formula:C20H23N5O2Purezza:99.77%Colore e forma:SolidPeso molecolare:365.43Ref: TM-T88080
1mg60,00€5mg127,00€10mg202,00€25mg416,00€50mg677,00€100mg1.074,00€200mg1.454,00€1mL*10mM (DMSO)140,00€SIRT5 inhibitor 5
CAS:SIRT5 inhibitor 5 is a selective and substrate-competitive SIRT5 inhibitor, which does not occupy the NAD+ binding pocket,cancer and metabolism-related disease.Formula:C21H14ClN3O3SPurezza:99.33%Colore e forma:SolidPeso molecolare:423.87SW155246
CAS:SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).Formula:C16H11ClN2O5SPurezza:98.99%Colore e forma:SolidPeso molecolare:378.79dWIZ-1
CAS:dWIZ-1 ((rac)-dWIZ-1) is a potent WIZ molecular gel degrader tha induction of haemoglobin fetalis (HbF) in erythroblasts, sickle cell disease (SCD).Formula:C22H29N3O4Purezza:92.87% - 92.87%Colore e forma:SolidPeso molecolare:399.48Peficitinib hydrobromide
CAS:Peficitinib hydrobromide is used in the treatment of Psoriasis and Rheumatoid Arthritis.Formula:C18H23BrN4O2Colore e forma:SolidPeso molecolare:407.312MAT2A-IN-5
CAS:MAT2A-IN-5 inhibits MAT2A in tumors, curbing growth in gastric, colon, liver, and pancreatic cancers.Formula:C17H12ClF3N2OColore e forma:SolidPeso molecolare:352.74SIRT6-IN-1
CAS:SIRT6-IN-1, a novel SIRT6 inhibitor, reduces glycemia and improves oral glucose tolerance in unfed wild-type mice.Formula:C19H14N4O5SColore e forma:SolidPeso molecolare:410.4CAY10722
CAS:CAY10722 is a SIRT3 inhibitor, affecting metabolism and cancer cell survival; varying impacts on esophageal and breast cancer.Formula:C21H14Cl2N2O2Colore e forma:SolidPeso molecolare:397.25GS-626510
CAS:GS-626510 is an orally bioavailable inhibitor of BET family bromodomains (Kd: 0.59-3.2 nM for BRD2/3/4; IC50: 83 nM and 78 nM for BD1 and BD2).Formula:C25H22N4OColore e forma:SolidPeso molecolare:394.47LW479
CAS:LW479 is a novel inhibitor of HDAC and is a promising candidate for the prevention of breast cancer.Formula:C21H23BrN2O4SColore e forma:SolidPeso molecolare:479.391,2,3,4,5,6-Hexabromocyclohexane
CAS:Inhibits JAK2 autophosphorylation; non-cytotoxic at 100μM; 1μM reduces activity by 50%, 50μM nearly abolishes it.Formula:C6H6Br6Purezza:98%Colore e forma:SolidPeso molecolare:557.54SPC-180002
CAS:SPC-180002, a dual SIRT1/3 inhibitor, exhibits IC50 values of 1.13 and 5.41 μM for SIRT1 and SIRT3, respectively.Formula:C18H23NO4Purezza:98%Colore e forma:SolidPeso molecolare:317.38KDM5A-IN-1
CAS:KDM5A-IN-1 is a pan-histidine lysine demethylase 5 KDM5 inhibitor that inhibits KDM5A, KDM5B, and KDM5C.Can be used in the study of cancer.Formula:C15H22N4O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:290.36SAR156497
CAS:SAR156497: selective Aurora A/B/C inhibitor; IC50: 0.5 nM (A), 1 nM (B), 3 nM (C); good metabolic stability; anti-tumoral without genetic specificity.Formula:C27H24N4O4Colore e forma:SolidPeso molecolare:468.5Tankyrase-IN-2
CAS:Tankyrase-IN-2 is a selective, potent and orally active inhibitor of tankyrase with IC50s of 10, 7, and 710 nM for TNKS1, TNKS2 as well as PARP1, respectivelyFormula:C17H14F2N2O2Purezza:98%Colore e forma:SolidPeso molecolare:316.36(5H)-Phenanthridinone
CAS:6(5H)-Phenanthridinone suppresses PARP1/2, reduces RDM4 cell growth, downregulates pro-inflammatory genes, and alleviates EAE symptoms in rats.Formula:C13H9NOColore e forma:SolidPeso molecolare:195.22NCC-149
CAS:NCC-149 is a HDAC8 inhibitor.Formula:C16H14N4O2SColore e forma:SolidPeso molecolare:326.37MS-1020
CAS:MS-1020 inhibits JAK3/STAT3, blocks active JAK3, suppresses JAK3/STAT5 signaling, and targets STAT3 in certain cells.Formula:C21H18N2O3Purezza:98%Colore e forma:SolidPeso molecolare:346.38AC-93253 iodide
CAS:AC-93253 iodide is a selective inhibitor of SIRT2. It significantly enhances the acetylation of tubulin p53 and histone H4.Formula:C23H25IN2SPurezza:98%Colore e forma:SolidPeso molecolare:488.43Ac-Lys-AMC
CAS:Ac-Lys-AMC (Hexanamide) is a fluorescent substrate for histone deacetylase HDACs.Formula:C18H23N3O4Purezza:98%Colore e forma:SolidPeso molecolare:345.39ZYJ-34v
CAS:ZYJ-34v is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities.Formula:C27H35N3O6Purezza:98%Colore e forma:SolidPeso molecolare:497.58NSC 698600
CAS:NSC 698600 is a potent inhibitor of PCAF(p300/CBP-associated factor) with IC 50 of 6.51 μM that shows good inhibition activity of cancer cell proliferation [1].Formula:C14H12N2O2SColore e forma:SolidPeso molecolare:272.32Tyk2-IN-5
CAS:Tyk2-IN-5 is a selective and orally active inhibitor of Tyk2 JH2 (Ki: 0.086 nM for Tyk2 JH2; IC50: 25 nM for IFNα).Formula:C21H19FN8O2Purezza:98%Colore e forma:SolidPeso molecolare:434.43JAK3/BTK-IN-2
CAS:<p>JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.</p>Formula:C25H32N8O2Purezza:99.64% - 99.87%Colore e forma:SolidPeso molecolare:476.57Bromodomain IN-1
CAS:Bromodomain IN-1 is an inhibitor of Bromodomain.Formula:C22H23ClN4O3SPurezza:98%Colore e forma:SolidPeso molecolare:458.96BET-BAY 002 (S enantiomer)
CAS:The S-enantiomer of BET-BAY 002, referred to as BET-BAY 002 S enantiomer, is a potent inhibitor of BET (Bromodomain and Extra-Terminal motif proteins).Formula:C22H18ClN5OPurezza:98%Colore e forma:SolidPeso molecolare:403.86TC-E 5001
CAS:dual tankyrase (TNKS) inhibitorFormula:C20H19N5O3SPurezza:98%Colore e forma:SolidPeso molecolare:409.46M133
CAS:M133 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.Formula:C23H24N4OS2Colore e forma:SolidPeso molecolare:436.59GW-841819X
CAS:GW841819X: (+)-JQ1 analogue, BET bromodomain inhibitor, active in vivo against various cancers.Formula:C25H21N5O2Colore e forma:SolidPeso molecolare:423.47OM-137
CAS:OM137 inhibits Aurora kinases, impedes cell growth at high doses, and enhances low-dose paclitaxel effects.Formula:C13H14N4O3SColore e forma:SolidPeso molecolare:306.34ZLD1039
CAS:ZLD1039, an oral EZH2 inhibitor, shows strong PRC2 inhibition at low nanomolar IC50s, and halts breast cancer growth and spread.Formula:C36H48N6O3Purezza:99.5%Colore e forma:SolidPeso molecolare:612.8GNA002
CAS:GNA002 is a highly potent, specific, and covalent EZH2 (Enhancer of zeste homolog 2) inhibitor (IC50: 1.1 μM).Formula:C42H55NO8Purezza:98%Colore e forma:SolidPeso molecolare:701.89ZIKV-IN-2
CAS:ZIKV-IN-2 blocks ZIKV replication, is a strong NS5 MTase inhibitor (IC50: 38.86 μM), and aids Zika virus research.Formula:C39H42O4Colore e forma:SolidPeso molecolare:574.75KU-0058684
CAS:KU-0058684 is a potent PARP and DNA-PK inhibitors.Formula:C19H14FN3O3Colore e forma:SolidPeso molecolare:351.33HOI-07
CAS:HOI-07 is a specific Aurora B inhibitor.Formula:C19H13NO4Colore e forma:SolidPeso molecolare:319.31ML753286
CAS:ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions.Formula:C20H25N3O3Purezza:98%Colore e forma:SolidPeso molecolare:355.43Trotabresib
CAS:Trotabresib (CC-90010) is an orally active inhibitor of BET and can be used in studies about advanced solid tumors.Formula:C21H21NO4SPurezza:99.86%Colore e forma:SolidPeso molecolare:383.46Ref: TM-T36395
1mg92,00€5mg188,00€10mg311,00€25mg528,00€50mg755,00€100mg1.017,00€1mL*10mM (DMSO)215,00€JAK1-IN-4
CAS:JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in NCI-H 1975 cells (IC50 = 227 nM).Formula:C26H32FN9O2Purezza:98%Colore e forma:SolidPeso molecolare:521.59CeMMEC2
CAS:CeMMEC2, a novel inhibitor of BRD4, binds both the first and the second bromodomain of BRD4.Formula:C14H19N5Colore e forma:SolidPeso molecolare:257.33Piribedil Maleate
CAS:Piribedil Maleate is a direct agonist of dopamine that acts by showing selectivity for the D3 subtype.Formula:C20H22N4O6Purezza:98%Colore e forma:SolidPeso molecolare:414.41AC430
CAS:AC430, a specific JAK2 inhibitor for cancer and autoimmune therapy, excels in preclinical trials with low doses. Developed by Ambit.Formula:C19H16FN5OColore e forma:SolidPeso molecolare:349.36Guadecitabine sodium
CAS:Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) .Formula:C18H24N9NaO10PPurezza:98%Colore e forma:SolidPeso molecolare:580.407DC_517
CAS:DC_517 is an inhibitor of DNA methyltransferase 1 (DNMT1) ( IC50: 1.7 μM; Kd: 0.91 μM).Formula:C33H35N3O2Colore e forma:SolidPeso molecolare:505.65L 888607 Racemate
CAS:L 888607 Racemate blocks DP1 and TP receptors with 132 nM and 17 nM affinity.Formula:C19H15ClFNO2SColore e forma:SolidPeso molecolare:375.84BAY-6035-R-isomer
CAS:BAY-6035 is an inhibitor of the methylation of MEKK2 peptide.Formula:C22H28N4O3Colore e forma:SolidPeso molecolare:396.48SC-9
CAS:SC-9 is a protein kinase C activator.Formula:C22H24ClNO2SPurezza:98%Colore e forma:SolidPeso molecolare:401.95TFMB-(S)-2-HG
CAS:TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase.Formula:C13H11F3O4Purezza:98.07%Colore e forma:SolidPeso molecolare:288.22Ref: TM-T24871
2mg35,00€5mg52,00€10mg84,00€25mg155,00€50mg240,00€100mg358,00€500mg753,00€1mL*10mM (DMSO)51,00€Tyk2-IN-7
CAS:Tyk2-IN-7 is an inhibitor of TYK2 JH2, binds to the TYK2 JH2 domain (IC50: 0.00053 μM; Ki.app: 0.00007 μM).Formula:C18H15D3N6O3SPurezza:98%Colore e forma:SolidPeso molecolare:401.46Pulrodemstat Methylbenzenesulfonate
CAS:LSD1-IN-7 Methylbenzenesulfonate is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.Formula:C31H31F2N5O5SPurezza:98%Colore e forma:SolidPeso molecolare:623.67Ilorasertib hydrochloride
CAS:Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s:Formula:C25H22ClFN6O2SPurezza:98.45%Colore e forma:SolidPeso molecolare:525Tetrahydrouridine
CAS:Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.Formula:C9H16N2O6Purezza:98%Colore e forma:SolidPeso molecolare:248.23KDM5B-IN-3
CAS:KDM5B-IN-3 inhibits KDM5B/JARID1B with IC50 of 9.32 μM, useful in gastric cancer studies.Formula:C19H25ClN4O2Colore e forma:SolidPeso molecolare:376.88
