Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2442 prodotti di "Cromatina/Epigenetica"
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(R)-UT-155
CAS:(R)-UT-155 is a selective androgen receptor degrader (SARD) ligand.Formula:C20H15F4N3O2Colore e forma:SolidPeso molecolare:405.35ARTD10/PARP10-IN-1
CAS:ARTD10/PARP10-IN-1 is a PARP inhibitor that inhibits ARTD8/PARP14 and has anticancer and antitumour activity for the study of prostate cancer.Formula:C12H12N2O4Purezza:99.14%Colore e forma:SolidPeso molecolare:248.23KCN1
CAS:KCN1: a synthetic sulfonamide, nanomolar HIF inhibitor with preclinical anti-glioma and anti-pancreatic cancer effects.Formula:C26H27NO5SColore e forma:SolidPeso molecolare:465.56SIRT2-IN-10
CAS:SIRT2-IN-10 (Compound 12) is a potent inhibitor of SIRT2 (IC50: 1.3 μM), which can be used in the study of cancer and neurodegenerative diseases.Formula:C28H21N5OSColore e forma:SolidPeso molecolare:475.56SB-429201
CAS:SB-429201 is an effective, selective inhibitor of HDAC1.Formula:C28H24N2O3Purezza:98%Colore e forma:SolidPeso molecolare:436.5JAK3-IN-9
CAS:JAK3-IN-9, potent JAK3 inhibitor, IC50 of 1.7 nM, highly selective, low toxicity, orally bioavailable, shows anti-arthritis activity.Formula:C17H23N5O4SColore e forma:SolidPeso molecolare:393.46Binucleine 2
CAS:Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.Formula:C13H11ClFN5Colore e forma:SolidPeso molecolare:291.71BRM/BRG1 ATP Inhibitor-3
CAS:BRM/BRG1 ATP Inhibitor-3 targets BRM/BRG1 (IC50: 10.4/19.3 nM) for cancer/BAF disorder research.Formula:C26H25N5O2S2Colore e forma:SolidPeso molecolare:503.64NCGC00247743
CAS:NCGC00247743 is an inhibitor of histone lysine demethylase KDM4.Formula:C24H29N3O2Purezza:98%Colore e forma:SolidPeso molecolare:391.51CPI-905
CAS:CPI-905 is a potent and selective EZH2 inhibitor with IC50 value of 39.5 nM.Formula:C18H20N2O5Colore e forma:SolidPeso molecolare:344.36LB-205
CAS:LB-205 is a Zn 2+ dependent pan-inhibitor of class I and class II HDACs. It also has a long half-life in vivo.Formula:C18H21N3O2SColore e forma:SolidPeso molecolare:343.44INCB16562
CAS:INCB16562: oral JAK1/2 inhibitor, halts IL-6/STAT3 in myeloma cells, boosts drug efficacy, stunts myeloma in mice.Formula:C19H11Cl2N5Colore e forma:SolidPeso molecolare:380.23Guadecitabine
CAS:Guadecitabine is a second-generation DNA methyltransferases inhibitor. It is used for research on acute myeloid leukemia and myelodysplastic syndromes.Formula:C18H24N9O10PPurezza:98%Colore e forma:SolidPeso molecolare:557.41DM-NOFD
CAS:DM-NOFD is a cell penetrant prodrug of NOFD, which is a potent and selective inhibitor of an asparaginyl hydroxylase FIH (factor-inhibiting HIF).Formula:C13H15NO5Colore e forma:SolidPeso molecolare:265.26NSD3-IN-2
CAS:NSD3-IN-2: Potent NSD3 inhibitor, IC50 17.97μM, halts NSCLC growth (H460, H1299, H1650) with anticancer effects.Formula:C17H15N5OSColore e forma:SolidPeso molecolare:337.4NSD3-IN-3
CAS:"NSD3-IN-3, a potent anticancer agent, inhibits NSD3 (IC50: 1.86 μM) and hampers H460 lung cancer cell growth."Formula:C15H17N5O2SColore e forma:SolidPeso molecolare:331.39Thi-DPPY
CAS:Thi-DPPY: Potent JAK3/BTK inhibitor (IC50: 1.38/62.4 nM), anti-proliferative, anti-inflammatory, potential in IPF research.Formula:C28H28ClN5O4SColore e forma:SolidPeso molecolare:566.07ZL0516
CAS:ZL0516, a chromone-based oral BRD4 BD1 inhibitor, shows potent in vivo efficacy and good pharmacokinetics, suggesting use in treating inflammation.Formula:C27H34N2O6Colore e forma:SolidPeso molecolare:482.57NC-III-49-1
CAS:NC-III-49-1: potent BET inhibitor, binds BRD4/BRDT, inhibits cell growth, reduces c-Myc expression.Formula:C44H50N4O11S2Colore e forma:SoildPeso molecolare:875.02iBRD4-BD1
CAS:iBRD4-BD1 inhibits BRD4 bromodomain selectively with 12 nM IC50, useful in inflammation and cancer research.Formula:C29H30F3N5OColore e forma:SolidPeso molecolare:521.58Bromodomain inhibitor-8
CAS:Bromodomain inhibitor-8 is an inhibitor of BET bromodomain used to treat autoimmune and inflammatory diseases.Formula:C26H25ClN2O3Colore e forma:SolidPeso molecolare:448.94Sirtuin modulator 4
CAS:Sirtuin modulator 4 inhibits SIRT1 (EC50: 51-100 μM), may extend cell life and prevent diseases like diabetes and cancer.Formula:C18H10N2O2SColore e forma:SolidPeso molecolare:318.35AMPK activator
CAS:AMPK activatorFormula:C22H21FO4Purezza:98%Colore e forma:SolidPeso molecolare:368.4HDAC-IN-44
CAS:HDAC-IN-44 is an HDAC inhibitor (IC50: 61.2 nM) with strong anti-cancer effects.Formula:C26H27BrN4O4Colore e forma:SolidPeso molecolare:539.42BET bromodomain inhibitor 2
CAS:BET bromodomain inhibitor 2 is a potent inhibitor of the BET-type bromodomain (IC50: 14.1 μM).Formula:C23H30N2O5SColore e forma:SolidPeso molecolare:446.56GDC-4379
CAS:GDC-4379 is a JAK1 inhibitor that can be used to study asthma.Formula:C21H18ClF2N7O3Colore e forma:SolidPeso molecolare:489.86HPCG
CAS:HPCG is an inhibitor of HIF-1α prolyl hydroxylase.Formula:C8H8N2O4Colore e forma:SolidPeso molecolare:196.16HDAC6-IN-10
CAS:HDAC6-IN-10 is a potent HDAC6 inhibitor with 0.73 nM IC50, highly selective, and hinders multiple myeloma cell growth.Formula:C21H20N4O4Colore e forma:SolidPeso molecolare:392.41Raxofelast
CAS:<p>Raxofelast (IRFI-016), a vitamin-like, hydrophilic antioxidant, mitigates ischemia-reperfusion in testis and may treat diabetic issues and atherosclerosis.</p>Formula:C15H18O5Purezza:99.74% - 99.97%Colore e forma:SolidPeso molecolare:278.3MAT2A-IN-9
CAS:MAT2A-IN-9, a 2-oxoquinazoline, inhibits MAT2A with antitumor effects on lymphomas and solid cancers.Formula:C14H8ClF3N4OPurezza:99.17%Colore e forma:SolidPeso molecolare:340.69Flosequinan
CAS:<p>Flosequinan is an arteriovenous vasodilator, which can effectively treat acute heart failure.</p>Formula:C11H10FNO2SPurezza:99.95%Colore e forma:SolidPeso molecolare:239.27SK-575
CAS:SK-575 is a potent PARP1-degrading agent effective against BRCA1/2 mutant cancers, even at low doses, and enhances tumor inhibition in mice.Formula:C47H53FN8O8Purezza:99.39%Colore e forma:SolidPeso molecolare:876.97JAK1-IN-8
CAS:<p>JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).</p>Formula:C22H23FN4O3SPurezza:98.4%Colore e forma:SolidPeso molecolare:442.51OUL232
CAS:OUL232 is a potent single ARTs PARP7, PARP10, PARP11, PARP12, PARP14 and PARP15 inhibitor for cancer and tumour research.Formula:C10H10N4O2SPurezza:99.04%Colore e forma:SolidPeso molecolare:250.28Bisaramil hydrochloride
CAS:Bisaramil hydrochloride (Bisaramil) is an antiarrhythmic compound that inhibits free radical production.Formula:C17H24Cl2N2O2Purezza:98.64% - 99.48%Colore e forma:SolidPeso molecolare:359.29Izencitinib
CAS:Izencitinib (JNJ-8398) is a JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.Formula:C22H26N8Purezza:99.82%Colore e forma:SolidPeso molecolare:402.50Ref: TM-T35898
1mg88,00€5mg187,00€10mg298,00€25mg597,00€50mg938,00€100mg1.510,00€200mg2.072,00€1mL*10mM (DMSO)207,00€CPUY074020
CAS:CPUY074020 is a potent and orally bioavailable inhibitor of histone methyltransferase G9a (IC50: 2.18 μM) with anti-proliferative activity.Formula:C25H28N4O2Purezza:98.64%Colore e forma:SolidPeso molecolare:416.52Ref: TM-T10882
1mg74,00€5mg156,00€10mg215,00€25mg338,00€50mg475,00€100mg620,00€200mg848,00€1mL*10mM (DMSO)168,00€GSK-690
CAS:<p>GSK-690 is a potent, reversible and selective inhibitors of Lysine Specific Demethylase 1.</p>Formula:C24H23N3OPurezza:98.65%Colore e forma:SolidPeso molecolare:369.46Butyrolactone 3
CAS:Butyrolactone 3 (MB-3) is a Gcn5 inhibitor with weak affinity for CBP.Butyrolactone 3 has antimicrobial activity and can be used in cancer.Formula:C9H12O4Purezza:98.99% - 99.5%Colore e forma:SolidPeso molecolare:184.19PF-249
CAS:PF-249 (PF-06685249) is a β1-selective AMPK with an EC50 of 12 nM for AMPK α1β1γ1 and can be used in studies about diabetic nephropathy.Formula:C17H16ClN3O3Purezza:97.01%Colore e forma:SolidPeso molecolare:345.78Ref: TM-T24626
1mg48,00€5mg97,00€10mg156,00€25mg250,00€50mg363,00€100mg510,00€200mg700,00€1mL*10mM (DMSO)105,00€LEM-14
CAS:<p>LEM-14 is a potent NSD2-specific inhibitor (IC50:132 μM).LEM-14 may be used in the study of multiple myeloma.</p>Formula:C25H26N4O4SPurezza:98.3%Colore e forma:SolidPeso molecolare:478.56R 59-022 hydrochloride
CAS:<p>R 59-022 hydrochloride is a 5-HT antagonist, PKC activator, DGK inhibitor (IC50: 2.8 µM), and modulates lipid production in platelets and neutrophils.</p>Formula:C27H27ClFN3OSPurezza:97.7%Colore e forma:SolidPeso molecolare:496.04DW14800
CAS:DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4α, and reduces the level of H4R3me2s.Formula:C31H36N4O3Purezza:99.55% - 99.68%Colore e forma:SolidPeso molecolare:512.64Ref: TM-T11131
1mg87,00€2mg130,00€5mg216,00€10mg378,00€25mg717,00€50mg948,00€100mg1.415,00€1mL*10mM (DMSO)245,00€CMP-5
CAS:CMP-5 is a PRMT5 inhibitor with antiviral activity, inhibits PRMT5 methyltransferase activity, and can be used in the study of SARS virus infection.Formula:C21H21N3Purezza:98.68%Colore e forma:SolidPeso molecolare:315.41Ref: TM-T10850
1mg47,00€5mg97,00€10mg144,00€25mg236,00€50mg354,00€100mg520,00€500mg1.111,00€1mL*10mM (DMSO)106,00€CD532
CAS:CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.Formula:C26H25F3N8OPurezza:99.99%Colore e forma:SolidPeso molecolare:522.52β-NF-JQ1
CAS:β-NF-JQ1 is a PROTAC that recruits aryl hydrocarbon receptor E3 (AhR E3) ligase to target proteins.Formula:C45H42ClN5O6SPurezza:97.58% - 99.15%Colore e forma:SolidPeso molecolare:816.36Corin
CAS:Corin is an irreversible inhibitor of HDAC1(IC50 = 147 nM) and LSD1(Ki = 110 nM).Formula:C26H28N4O2Purezza:99.6%Colore e forma:SolidPeso molecolare:428.53Ref: TM-T10864
1mg170,00€5mg432,00€10mg638,00€25mg1.008,00€50mg1.359,00€100mg1.825,00€1mL*10mM (DMSO)465,00€ZEN-2759
CAS:ZEN-2759 is a potent BET small molecule inhibitor of BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2).Formula:C17H16N2O2Purezza:99.36%Colore e forma:SolidPeso molecolare:280.32PARP10-IN-2
CAS:<p>PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 and</p>Formula:C14H10N2O2Purezza:99.27%Colore e forma:SolidPeso molecolare:238.24BRD4 Inhibitor-20
CAS:<p>BRD4 Inhibitor-20 is a potent bromodomain protein 4 (BRD4) inhibitor with oral activity.</p>Formula:C18H18N2O4SPurezza:99.84%Colore e forma:SolidPeso molecolare:358.41GRK6-IN-1
CAS:GRK6-IN-1 (compound 18) is a potent GRK6 blocker, with an IC50 of 120 nM, showing promise for multiple myeloma research.Formula:C22H23ClN6O2Purezza:99.37%Colore e forma:SolidPeso molecolare:438.91Ref: TM-T62518
1mg57,00€5mg120,00€10mg188,00€25mg432,00€50mg747,00€100mg1.216,00€1mL*10mM (DMSO)133,00€OXF BD 02
CAS:OXF BD 02 is a potent and selective BRD4(1) inhibitor (IC50: 382 nM) with anticancer and anti-inflammatory activity.Formula:C18H17NO3Purezza:98.25%Colore e forma:SolidPeso molecolare:295.33BAY-299
CAS:BAY-299 inhibits BRPF2, TAF1, and TAF1L with IC50s of 67, 8, and 106 nM.Formula:C25H23N3O4Purezza:99.53%Colore e forma:SolidPeso molecolare:429.47TGP-377/421
CAS:TGP-377/421 (Targapre-miR-377/421) is a potent miR-377 and miR-421 dual inhibitor that inhibits miR-377 and miR-421 by binding to their functional sites.Formula:C20H16N6Purezza:97.02%Colore e forma:SolidPeso molecolare:340.38Ref: TM-T61085
1mg66,00€5mg144,00€10mg227,00€25mg454,00€50mg733,00€100mg1.026,00€500mg2.052,00€1mL*10mM (DMSO)159,00€Butyzamide
CAS:<p>Butyzamide: oral Mpl activator, non-peptide, antagonizes TPO receptors, boosts hMpl, Ba/F3 cells, and enhances platelets in mice.</p>Formula:C29H32Cl2N2O5SPurezza:99.51% - 99.83%Colore e forma:SoildPeso molecolare:591.55Ref: TM-T67894
1mg158,00€5mg266,00€10mg393,00€25mg605,00€50mg909,00€100mg1.378,00€200mg1.853,00€1mL*10mM (DMSO)346,00€DCPLA-ME
CAS:DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerativeFormula:C21H38O2Purezza:99.80%Colore e forma:SolidPeso molecolare:322.53Ref: TM-T10980
1mg65,00€5mg133,00€10mg180,00€25mg369,00€50mg605,00€100mg815,00€200mg1.111,00€1mL*10mM (DMSO)145,00€HDAC6 degrader 9c
CAS:HDAC6 degrader 9c is a small molecule histone deacetylase 6 (HDAC6) degrader that can be used to study cancer or other diseases.Formula:C37H45N9O10Purezza:>99.99%Colore e forma:SolidPeso molecolare:775.81TNG908
CAS:TNG908, a brain-penetrant PRMT5 inhibitor, is 15x more selective for MTAP mutant vs WT lines, useful in cancer studies.Formula:C21H23N5O2SPurezza:98.08% - 98.24%Colore e forma:SolidPeso molecolare:409.51Ref: TM-T73494
1mg70,00€5mg154,00€10mg235,00€25mg378,00€50mg540,00€100mg747,00€1mL*10mM (DMSO)166,00€ZEN-3862
CAS:ZEN-3862, a BET inhibitor, blocks BRD4(BD1) at 0.16 μM & BRD4(BD2) at 0.13 μM; usable in PROTACs for BRD4 degradation.Formula:C19H17FN2O3Purezza:97.1%Colore e forma:SolidPeso molecolare:340.35ML192
CAS:ML192 (CID1434953) is a selective GPR55 ligand antagonist.Formula:C20H22N4O2SPurezza:99.17%Colore e forma:SolidPeso molecolare:382.48Ref: TM-T33452
1mg35,00€5mg74,00€10mg110,00€25mg182,00€50mg263,00€100mg369,00€200mg507,00€1mL*10mM (DMSO)96,00€EB-47
CAS:EB-47 imitates NAD+, spans nicotinamide to adenosine sites, inhibits PARP-1 (IC50: 45 nM) and is less effective on ARTD5 (IC50: 410 nM).Formula:C24H27N9O6Purezza:99.81%Colore e forma:SolidPeso molecolare:537.53KRH102140
CAS:KRH102140 is a PHD2 activator that reduces angiogenesis by inhibiting HIF-1alpha, used in cardiovascular disease research.Formula:C25H24FNOPurezza:98.31% - 99.61%Colore e forma:SolidPeso molecolare:373.46DC-BPi-03
CAS:DC-BPi-03 is a potent BPTF-BRD inhibitor with an IC 50 of 698.3 nM and a K d of 2.81 μM .Formula:C14H14N4O2SPurezza:98.96%Colore e forma:SolidPeso molecolare:302.35MS0124
CAS:<p>MS0124 is a potent and selective G9A-like protein (GLP) inhibitor with IC50 values of 13±4 nM and 440±63 nM, respectively.</p>Formula:C20H29N5O3Purezza:98.97%Colore e forma:SolidPeso molecolare:387.48EZH2-IN-13
CAS:EZH2-IN-13 is a potent EZH2 inhibitor with potential anticancer activity.EZH2-IN-13 may be used to study diseases associated with EZH2 activity.Formula:C34H45N5O3Purezza:98.3%Colore e forma:SolidPeso molecolare:571.75Bobcat339 hydrochloride
CAS:Bobcat339 hydrochloride is a 10 11 translocation (TET) dioxygenase inhibitor that inhibits both TET1 and TET2.Formula:C16H13Cl2N3OPurezza:99.22%Colore e forma:SolidPeso molecolare:334.2Ref: TM-T61012
2mg35,00€5mg52,00€10mg85,00€25mg160,00€50mg250,00€100mg373,00€200mg547,00€1mL*10mM (DMSO)58,00€Procainamide
CAS:Procainamide: DNMT1 inhibitor, Class 1A antiarrhythmic, promising for cancer and arrhythmia research.Formula:C13H21N3OPurezza:99.79% - 99.92%Colore e forma:SolidPeso molecolare:235.33ZEN-3411
CAS:ZEN-3411 is an BET inhibitor that inhibits BRD4(BD1), BRD4(BD2), and BRD4(BD1BD2) and suppresses the growth of tumor cells overproducing BET proteins.Formula:C21H20N4O2Purezza:97.51% - 98.84%Colore e forma:SolidPeso molecolare:360.41OXFBD04
CAS:OXFBD04: Potent BRD4 inhibitor, IC50=166nM, acts on BET bromodomains; moderate CREBBP affinity; anti-cancer properties.Formula:C17H16N2O3Purezza:99.56%Colore e forma:SolidPeso molecolare:296.32Ref: TM-T12338
1mg52,00€2mg78,00€5mg115,00€10mg182,00€25mg339,00€50mg505,00€100mg685,00€200mg944,00€1mL*10mM (DMSO)126,00€Crebinostat
CAS:Crebinostat: potent HDAC inhibitor, boosts synapsin-1 in neurons, enhances memory and gene Egr1 expression in mice.Formula:C20H23N3O3Purezza:99.49%Colore e forma:SolidPeso molecolare:353.41Cedazuridine
CAS:Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.Formula:C9H14F2N2O5Purezza:99.66%Colore e forma:SolidPeso molecolare:268.21TM2-115
CAS:TM2-115 is a inhibitor of malaria parasite histone methyltransferases that results in rapid and irreversible parasite death [1].Formula:C28H38N6O2Purezza:97.67%Colore e forma:SolidPeso molecolare:490.64CARM1-IN-1
CAS:CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.Formula:C26H21Br2NO3Purezza:98.24%Colore e forma:SolidPeso molecolare:555.26Ref: TM-T10682L
1mg37,00€5mg88,00€10mg127,00€25mg250,00€50mg406,00€100mg632,00€200mg883,00€1mL*10mM (DMSO)97,00€PU139
CAS:<p>PU139 is a novel inhibitor of histone acetyltransferase (HAT).</p>Formula:C12H7FN2OSPurezza:99.96%Colore e forma:SolidPeso molecolare:246.26CEP-9722
CAS:CEP-9722 is a PARP-1 and PARP-2 inhibitor with anticancer activity and is used in the study of ovarian cancer.Formula:C24H26N4O3Purezza:98.38% - 98.56%Colore e forma:SolidPeso molecolare:418.49JAK-STAT-IN-1
CAS:JAK-STAT-IN-1 is a specific JAK-STAT inhibitor indicated for the study of autoimmune diseases.Formula:C21H21N5O2Purezza:99.59%Colore e forma:SolidPeso molecolare:375.42AGI-43192
CAS:<p>AGI-43192: potent MAT2A inhibitor, crosses blood-brain barrier, may help study SAM in CNS and treat cancer.</p>Formula:C23H16ClF3N6OPurezza:99.89%Colore e forma:SolidPeso molecolare:484.86YLF-466D
CAS:YLF-466D (C24) is a newly developed AMPK activator, which inhibits platelet aggregation.Formula:C29H20ClNO3Purezza:97.74%Colore e forma:SolidPeso molecolare:465.93Ref: TM-T13368
1mg37,00€5mg84,00€10mg117,00€25mg198,00€50mg284,00€100mg393,00€200mg540,00€1mL*10mM (DMSO)87,00€AGI-24512
CAS:AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells inFormula:C24H24N4O2Purezza:98.55%Colore e forma:SolidPeso molecolare:400.47Ref: TM-T14141
1mg70,00€5mg154,00€10mg235,00€25mg378,00€50mg540,00€100mg747,00€200mg1.035,00€1mL*10mM (DMSO)207,00€NSC 694623
CAS:NSC 694623: Potent HAT inhibitor, IC50=15.9 μM against PCAF, anti-cancer properties.Formula:C16H16N2OSPurezza:99.9%Colore e forma:SolidPeso molecolare:284.38ZEN-3219
CAS:ZEN-3219 is a BET inhibitor, which has inhibitory effect on BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2).Formula:C19H18N2O3Purezza:99.86%Colore e forma:SolidPeso molecolare:322.36Chiauranib
CAS:<p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>Formula:C27H21N3O3Purezza:99.22%Colore e forma:SolidPeso molecolare:435.47STS-E412
CAS:STS-E412 is a tissue-protective and selective EPOR/CD131 receptor activator for the study of neurological disorders.Formula:C15H15ClN4O2Purezza:99.01%Colore e forma:SolidPeso molecolare:318.76LSD1-IN-20
CAS:LSD1-IN-20: Dual LSD1/G9a inhibitor, Ki 0.44/0.68 μM; hampers THP-1, MDA-MB-231 cell growth with IC50 0.51/1.60 μM at 72h.Formula:C27H38N6O2Purezza:97.17% - 99.57%Colore e forma:SolidPeso molecolare:478.63SIRT5 inhibitor 7
CAS:SIRT5 inhibitor 7 , a substrate-competitive and selective SIRT5 inhibitor, significantly attenuated renal dysfunction and pathological damage in AKI mice.Formula:C28H32ClN7O3SPurezza:99.77%Colore e forma:SolidPeso molecolare:582.12NMS-P515
CAS:NMS-P515 is an effective, orally active, and stereospecific PARP-1 inhibitor (Kd: 16 nM and an IC50: 27 nM (in Hela cells)). It has anti-tumor activity.Formula:C21H29N3O2Purezza:98%Colore e forma:SolidPeso molecolare:355.47TC-A 2317 hydrochloride
CAS:TC-A 2317 HCl inhibits Aurora A kinase (Ki 1.2 nM) over Aurora B (Ki 101 nM), displaying antitumor effects.Formula:C19H29ClN6OPurezza:98%Colore e forma:SolidPeso molecolare:392.93PIM-IN-2
CAS:PIM-IN-2 (Pim-2) is a potent inhibitor of Pim kinases, demonstrating an inhibition concentration half-maximal (IC50) value of 25 nM .Formula:C19H22N4O2Purezza:98%Colore e forma:SolidPeso molecolare:338.4TCS 21311
CAS:<p>TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.</p>Formula:C27H25F3N4O4Purezza:99.39% - ≥98%Colore e forma:SolidPeso molecolare:526.51MS023 trihydrochloride
CAS:MS023 trihydrochloride (MS023 3HCl) is a PRMT inhibitor with potential anticancer activity against PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8 for cancer research.Formula:C17H28Cl3N3OPurezza:99.81%Colore e forma:SolidPeso molecolare:396.78Nesuparib
CAS:Nesuparib, a potent PARP/TNKS1 inhibitor, has antitumor properties and potential for treating various diseases.Formula:C23H24N6OPurezza:99.94%Colore e forma:SolidPeso molecolare:400.48Ref: TM-T61932
1mg88,00€5mg210,00€10mg338,00€25mg605,00€50mg825,00€100mg1.121,00€1mL*10mM (DMSO)233,00€HSP70/SIRT2-IN-2
CAS:<p>HSP70/SIRT2-IN-2 (Compounds 1a), a dual inhibitor of SIRT2 and HSP70, exhibits an IC50 of 45.1±5.0 μM against SIRT2 and demonstrates antitumor activity [1].</p>Formula:C17H13N3S3Purezza:98%Colore e forma:SolidPeso molecolare:355.5JAK2-IN-4
CAS:JAK2-IN-4 is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively.Formula:C23H27N5O4SPurezza:98%Colore e forma:SolidPeso molecolare:469.56PARP7-IN-16
CAS:PARP7-IN-16 (compound 36) is a potent, selective, and orally active PARP-1/2/7 inhibitor, exhibiting IC50 values of 0.94, 0.87, and 0.21 nM , respectively.Formula:C25H26FN4NaO4Purezza:98%Colore e forma:SolidPeso molecolare:488.49KDM5-IN-1
CAS:KDM5-IN-1 is an effective and selective inhibitor of KDM5 with an IC50 of 15.1 nM.Formula:C17H20N6OPurezza:99.50%Colore e forma:SolidPeso molecolare:324.38Ref: TM-T15649
1mg64,00€5mg187,00€10mg284,00€25mg452,00€50mg645,00€100mg867,00€500mgPrezzo su richiesta1mL*10mM (DMSO)137,00€PHD-IN-1
CAS:<p>PHD-IN-1 (compound 80) serves as a potent PHD2 inhibitor, exhibiting an IC50 value of ≤5 nM.</p>Formula:C24H23N7O2Purezza:98%Colore e forma:SolidPeso molecolare:441.49PARP1-IN-7
CAS:PARP1-IN-7 functions as an anticancer agent by inhibiting poly(ADP-ribose) polymerase-1 (PARP1).Formula:C24H23N5OColore e forma:SolidPeso molecolare:397.47HIF-2α-IN-13
CAS:HIF-2α-IN-13 (18) acts as a HIF-2α inhibitor and exhibits an IC 50 value of 2.7 μM.Formula:C15H14ClF4NO2Colore e forma:SolidPeso molecolare:351.72Ro 32-0432 hydrochloride
CAS:Ro 32-0432 is a selective, ATP-competitive, oral pan-PKC inhibitor exhibiting inhibitory effects on PKCα, PKCβI, PKCβII, PKCγ, and PKCε.Formula:C28H28N4O2Purezza:98%Colore e forma:SolidPeso molecolare:452.55KF21213
CAS:KF21213 shows a high affinity for the adenosine A2A receptors (Ki=3.0 nM). KF21213 is a highly selective ligand for mapping CNS adenosine A2A receptors.Formula:C19H22N4O3Purezza:98%Colore e forma:SolidPeso molecolare:354.4
