Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2442 prodotti di "Cromatina/Epigenetica"
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Boc-Lys(Ac)-AMC
CAS:Boc-Lys(Ac)-AMC (Boc-L-Lys(Ac)-AMC) is a synthetic substrate coupled to an HDAC-specific fluorophore (Ex/Em = 355 nm/460 nm).Formula:C23H31N3O6Purezza:99.87%Colore e forma:SolidPeso molecolare:445.51Ref: TM-T36578
5mg49,00€10mg80,00€25mg136,00€50mg192,00€100mg283,00€200mg409,00€1mL*10mM (DMSO)54,00€MC4171
MC4171 is a selective KAT8 inhibitor with antiproliferative activity and can be used to study cancer.Formula:C21H15N3O3Purezza:99.56%Colore e forma:SolidPeso molecolare:357.36PROTAC PARP1 degrader
CAS:PROTAC PARP1 degrader suppresses MDA-MB-231 cells at 10 μM, IC50: 6.12 μM in 24h.Formula:C58H63Cl2N11O10Purezza:98%Colore e forma:SolidPeso molecolare:1145.1GSK2879552
CAS:GSK2879552: oral, irreversible LSD1 inhibitor with potential cancer-fighting properties.Formula:C23H28N2O2Purezza:99.22%Colore e forma:SolidPeso molecolare:364.48AZ505 ditrifluoroacetate
CAS:AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12 μM).Formula:C33H40Cl2F6N4O8Colore e forma:SolidPeso molecolare:805.59T-448
CAS:T-448 is a lysine-specific demethylase 1 inhibitor (IC50: 22 nM) that improves learning function in mice.T-448 can be used to study memory deficits.Formula:C19H22N4O3SPurezza:97% - 98.63%Colore e forma:SolidPeso molecolare:386.47GSK778
CAS:GSK778 selectively inhibits BD1 bromodomains (BRD2, BRD3, BRD4, BRDT) and impedes cell growth, causing arrest and apoptosis.Formula:C30H33N5O3Purezza:98.42%Colore e forma:SolidPeso molecolare:511.61Ref: TM-T9703
1mg160,00€5mg311,00€10mg502,00€25mg1.008,00€50mg1.596,00€100mg2.213,00€1mL*10mM (DMSO)47,00€JET-209
JET-209 is a potent proteolysis-targeting chimera (PROTAC) that effectively degrades CBP/p300, exhibiting half-maximal degradation concentration (DC50) valuesFormula:C46H47N9O6Purezza:98%Colore e forma:SolidPeso molecolare:821.92(2R)-Octyl-α-hydroxyglutarate
CAS:(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a D-isomer 2-Hydroxyglutarate modified form.Formula:C13H24O5Colore e forma:SolidPeso molecolare:260.33Atinvicitinib
CAS:Atinvicitinib, a selective JAK1 inhibitor, blocks cytokine signaling, modulating itch, allergy, and inflammatory responses, immune and therapeutic studies.Formula:C16H17FN6O3Purezza:99.36%Colore e forma:SolidPeso molecolare:360.35Ref: TM-T39646
1mg145,00€5mg354,00€10mg582,00€25mg1.121,00€50mg1.833,00€100mg2.688,00€1mL*10mM (DMSO)279,00€SGC-iMLLT
CAS:SGC-iMLLT is a potent and selective MLLT1/3-histone interactions inhibitor(IC50 = 0.26 μM),and is a first-in-class chemical probe displaying cellular targetFormula:C22H24N6OPurezza:99.21% - 99.92%Colore e forma:SolidPeso molecolare:388.47TPOP146
CAS:TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4).Formula:C27H35N3O5Purezza:98%Colore e forma:SolidPeso molecolare:481.58KDM4C-IN-1
CAS:KDM4C-IN-1 is aKDM4C inhibitor withial anticancer activity.KDM4C-IN-1 inhibits the growth of HepG2 and A549 cells, and can be used for the study of leukaemia.Formula:C15H14N4O3Purezza:99.33%Colore e forma:SolidPeso molecolare:298.3Pim-1/2 kinase inhibitor 1
CAS:Orally active Pim-1/2 inhibitor blocks kinase phosphorylation; used in prostate cancer research.Formula:C11H9NO3SPurezza:99.78%Colore e forma:SolidPeso molecolare:235.262'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride
CAS:2'-Deoxy-2'-fluoro-beta-D-arabinocytidine HCl inhibits DNA methyltransferase with potential anti-tumor properties.Formula:C9H13ClFN3O4Purezza:99.43%Colore e forma:SolidPeso molecolare:281.67DTP3
CAS:DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.Formula:C26H35N7O5Colore e forma:SolidPeso molecolare:525.6GSK9311
CAS:GSK9311 inhibits BRPF bromodomain (pIC50: 6.0 and 4.3 for BRPF1 and BRPF2, respectively).Formula:C24H31N5O3Purezza:98%Colore e forma:SolidPeso molecolare:437.53MS8511 hydrochloride
CAS:<p>MS8511 hydrochloride is a selective G9a/GLP inhibitor with IC50 values of 100 nM and 140 nM respectively, exhibiting covalent and irreversible characteristics.</p>Formula:C28H42ClN5O3Colore e forma:SolidPeso molecolare:532.12ADTL-SA1215
CAS:ADTL-SA1215 is a SIRT3 activator with SIRT3 deacetylase activity for the study of triple negative breast cancer.Formula:C26H29I2NO3Purezza:99.23%Colore e forma:SolidPeso molecolare:657.32(±)-1,2-Diolein
CAS:(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.Formula:C39H72O5Colore e forma:SolidPeso molecolare:620.99O6BTG-octylglucoside
CAS:O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).Formula:C24H34BrN5O7SPurezza:98%Colore e forma:SolidPeso molecolare:616.531,4-DPCA ethyl ester
CAS:1,4-DPCA ethyl ester is a form of 1,4-DPCA modified, which has potential anticancer activity based on growth inhibition assays with the mlh1 rad18 yeast strain.Formula:C15H12N2O3Purezza:99.54%Colore e forma:SolidPeso molecolare:268.27Ref: TM-T36796
2mg38,00€5mg57,00€10mg95,00€25mg166,00€50mg270,00€100mg458,00€200mg657,00€1mL*10mM (DMSO)63,00€Ilunocitinib
CAS:Ilunocitinib is a non-selective and orally active Janus kinase (JAK) inhibitor for pruritus and atopic dermatitis caused by atopic dermatitis in dogs.Formula:C17H17N7O2SPurezza:99.88%Colore e forma:SolidPeso molecolare:383.43Ref: TM-T38571
1mg97,00€5mg243,00€10mg376,00€25mg753,00€50mg1.254,00€100mg1.890,00€200mg2.547,00€1mL*10mM (DMSO)265,00€GSK-J2
CAS:GSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.Formula:C22H23N5O2Purezza:97.55%Colore e forma:SolidPeso molecolare:389.45Ref: TM-T11476
1mg35,00€5mg74,00€10mg97,00€25mg165,00€50mg235,00€100mg346,00€200mg515,00€1mL*10mM (DMSO)106,00€DA-3003-1
CAS:DA-3003-1 (NSC 663284) is a Cdc25 dual specificity phosphatase inhibitor with antitumor activity and inhibits Cdc25B2, Cdc25A, Cdc25B2, and Cdc25C.Formula:C15H16ClN3O3Purezza:99.27% - 99.79%Colore e forma:SolidPeso molecolare:321.76BAY-850
CAS:BAY-850 is ainhibitor of adenosine triphosphatase family protein 2 that inhibits ovarian cancer growth and metastasis in in vitro and in vivo models.Formula:C38H44ClN5O3Purezza:98% - 98%Colore e forma:SolidPeso molecolare:654.24CHZ868
CAS:CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.Formula:C22H19F2N5O2Purezza:99.38%Colore e forma:SolidPeso molecolare:423.42SIRT-IN-3
CAS:SIRT-IN-3: potent SIRT1 inhibitor (IC50=17μM), 4x selective over SIRT2, 14x over SIRT3 (IC50s: 74μM & 235μM).Formula:C13H12N2OColore e forma:SolidPeso molecolare:212.25KDM4-IN-3
CAS:KDM4-IN-3 is a KDM4 inhibitor that is cell-permeable and kills prostate cancer cells at low micromolar concentrations.Formula:C17H14N4OColore e forma:SolidPeso molecolare:290.32Anti-PARP1 Antibody (8I163)
Anti-PARP1 Antibody (8I163) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (8I163) can be used in IHC-P.Colore e forma:Odour LiquidNSC 694621
CAS:NSC 694621 is a PCAF inhibitor that forms a covalent bond with Cys574, irreversibly inhibiting its acetyltransferase activity, inhibit proliferation,anticancer.Formula:C13H10N2O2SPurezza:99.7%Colore e forma:SolidPeso molecolare:258.3Anti-PARP Antibody (1W26)
Anti-PARP Antibody (1W26) is a Mouse antibody targeting PARP. Anti-PARP Antibody (1W26) can be used in WB,IHC-P,IP.Colore e forma:Odour LiquidAnti-PARP1 Antibody (6I459)
Anti-PARP1 Antibody (6I459) is an antibody targeting PARP1. Anti-PARP1 Antibody (6I459) can be used in ELISA, IHC.Colore e forma:Odour LiquidAnti-PARP1 Antibody (7A800)
Anti-PARP1 Antibody (7A800) is an antibody targeting PARP1. Anti-PARP1 Antibody (7A800) can be used in ELISA, WB, IHC.Colore e forma:Odour LiquidAnti-PARP1 Antibody (9E313)
Anti-PARP1 Antibody (9E313) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (9E313) can be used in IHC-P.Colore e forma:Odour LiquidAnti-PARP1 Antibody (8S756)
Anti-PARP1 Antibody (8S756) is an antibody targeting PARP1. Anti-PARP1 Antibody (8S756) can be used in ELISA, WB, IHC, IF, FCM.Colore e forma:Odour LiquidGintemetostat
CAS:Gintemetostat (KTX-1001) is a potent NSD2 inhibitor (IC50=0.001-0.01μM) for treating NSD2-dysregulated cancers.Formula:C25H26F4N8O2Colore e forma:SolidPeso molecolare:546.52Fenbendazole-d3
CAS:Fenbendazole-d3 is a deuterated compound of Fenbendazole. Fenbendazole has a CAS number of 43210-67-9. Fenbendazole is an antinematodal benzimidazole used in veterinary medicine.Formula:C15H10D3N3O2SColore e forma:SolidPeso molecolare:302.37(R)-GSK-3685032
CAS:(R)-GSK-3685032 is a selective, reversible DNMT1 inhibitor, non-covalent, IC50: 0.036 μM; reduces DNA methylation, inhibits cancer growth.Formula:C22H24N6OSColore e forma:SolidPeso molecolare:420.54CX-6258 hydrochloride hydrate
CAS:CX-6258 hydrochloride hydrate is a potent and selective inhibitor of pan-Pim kinase that acts on Pim-1 (IC50: 5 nM), Pim-2 (IC50: 25 nM) and Pim-3 (IC50: 16 nMFormula:C26H27Cl2N3O4Colore e forma:SolidPeso molecolare:516.42INO-1001
CAS:INO-1001: potent PARP inhibitor with antitumor properties, enhances radiosensitivity & radiation-induced cell death.Formula:C23H25N3O4SColore e forma:SolidPeso molecolare:439.53N-Descyclopropanecarbaldehyde Olaparib
CAS:N-Descyclopropanecarbaldehyde Olaparib is a CRBN ligand for dual EGFR/PARP PROTAC, suitable for F-18 radiolabeling and tumor imaging via PET.Formula:C20H19FN4O2Colore e forma:SolidPeso molecolare:366.397-Chloro-4-(piperazin-1-yl)quinoline
CAS:7-Cl-4-(piperazin-1-yl)quinolone: sirtuin inhibitor, serotonin uptake blocker, antimalarial (D10 IC50 1.18µM, K1 IC50 0.97µM).Formula:C13H14ClN3Purezza:99.52%Colore e forma:Light Yellow SolidPeso molecolare:247.72AMI-1 free acid
CAS:<p>AMI-1: Potent reversible PRMT inhibitor; IC50: 8.8 μM (hPRMT1), 3.0 μM (yeast-Hmt1p); blocks substrate binding.</p>Formula:C21H16N2O9S2Purezza:97.8%Colore e forma:SolidPeso molecolare:504.49EM127
CAS:EM127: covalent SMYD3 inhibitor, KD 13μM, impedes ERK1/2, hinders SMYD3 gene regulation, long-term methyltransferase reduction, potential in cancer study.Formula:C14H18ClN3O3Purezza:97.55%Colore e forma:SolidPeso molecolare:311.76WP1066
CAS:WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formula:C17H14BrN3OPurezza:98.92% - 99.73%Colore e forma:SolidPeso molecolare:356.22AMPK activator 2
CAS:AMPK activator 2, a chloroformin derivative, may boost cancer treatment by enhancing AMPK and inhibiting mTOR pathways, and cancer cell growth.Formula:C13H18F3N5Purezza:99.86%Colore e forma:SolidPeso molecolare:301.31TCS PIM-1 1
CAS:TCS PIM-1 1 (SC 204330) is a potent ATP-competitive inhibitor of Pim-1 kinase with an IC50 of 50 nM, selective over MEK1/2 and Pim-2.Formula:C18H11BrN2O2Purezza:97% - 97.98%Colore e forma:SolidPeso molecolare:367.2Ref: TM-T2253
1mg35,00€5mg64,00€10mg88,00€25mg187,00€50mg284,00€100mg424,00€200mg612,00€1mL*10mM (DMSO)97,00€BI-7273
CAS:BI-7273 is an effective, specific, BRD9 BD Inhibitor, which can infiltrate cell.Formula:C20H23N3O3Purezza:97.37% - 99.57%Colore e forma:SolidPeso molecolare:353.41Rucaparib monocamsylate
CAS:<p>Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.</p>Formula:C29H34FN3O5SPurezza:99.82%Colore e forma:SolidPeso molecolare:555.66PF-CBP1
CAS:PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).Formula:C29H36N4O3Purezza:99.45%Colore e forma:SolidPeso molecolare:488.62BIX-01294
CAS:BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).Formula:C28H38N6O2Purezza:98.58% - 99.64%Colore e forma:SolidPeso molecolare:490.64Ref: TM-T7697
1mg40,00€5mg85,00€10mg117,00€25mg207,00€50mg311,00€100mg472,00€200mg642,00€1mL*10mM (DMSO)131,00€PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purezza:98.82%Colore e forma:SolidPeso molecolare:394.473-methyl-1,2-dihydroquinolin-2-one
CAS:3-methyl-1,2-dihydroquinolin-2-one is the first known micromolar inhibitors of the ATAD2 bromodomain.Formula:C10H9NOPurezza:99.62%Colore e forma:SolidPeso molecolare:159.18Ref: TM-T50035
1mg38,00€5mg81,00€10mg108,00€25mg178,00€50mg264,00€100mg374,00€200mg507,00€1mL*10mM (DMSO)65,00€Aurora kinase inhibitor-3
CAS:Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,Formula:C21H18F3N5OPurezza:98.91%Colore e forma:SolidPeso molecolare:413.4Ref: TM-T5524
1mg70,00€2mg95,00€5mg160,00€10mg250,00€25mg424,00€50mg612,00€100mg842,00€200mg1.159,00€1mL*10mM (DMSO)170,00€NSC 228155
CAS:NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.Formula:C11H6N4O4SPurezza:99.84%Colore e forma:SolidPeso molecolare:290.25Ref: TM-T6908
2mg35,00€5mg50,00€10mg66,00€25mg124,00€50mg188,00€100mg354,00€200mg495,00€1mL*10mM (DMSO)52,00€653-47
CAS:653-47 enhances the effects of 666-15 on inhibiting CREB and is a mild CREB inhibitor itself (IC50: 26.3μM).Formula:C20H19ClN2O3Colore e forma:SolidPeso molecolare:370.83BI-9564
CAS:<p>BI-9564, a specific cell-permeable BRD9 BD inhibitor. The Kd for BRD9 is 5.9 nM, and IC50 for BET family is > 100 μM.</p>Formula:C20H23N3O3Purezza:99.38%Colore e forma:SolidPeso molecolare:353.41Senaparib hydrochloride
CAS:Senaparib hydrochloride is a potent and selective oral PARP1/2 inhibitor with strong antitumor activity.Formula:C24H21ClF2N6O3Colore e forma:SolidPeso molecolare:514.92Hesperadin
CAS:Hesperadin(IC50=250 nM) effectively inhibits Aurora B.Formula:C29H32N4O3SPurezza:98.04% - 99.44%Colore e forma:SolidPeso molecolare:516.65Ritlecitinib
CAS:Ritlecitinib (PF-06651600) is an orally available, selective JAK3 inhibitor and does not affect the activity of JAK1/2.Cost-effective and quality-assured.Formula:C15H19N5OPurezza:98.82% - 99.92%Colore e forma:SolidPeso molecolare:285.34Ref: TM-T5382
2mg39,00€5mg56,00€10mg96,00€25mg216,00€50mg306,00€100mg430,00€200mg628,00€1mL*10mM (DMSO)77,00€Selisistat
CAS:Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50=38 nM).Formula:C13H13ClN2OPurezza:98.53% - 99.94%Colore e forma:SolidPeso molecolare:248.71Ref: TM-T6111
5mg50,00€10mg57,00€25mg93,00€50mg140,00€100mg235,00€200mg349,00€500mg565,00€1mL*10mM (DMSO)52,00€6-Bromo-3-methyl-1,4-dihydroquinazolin-2-one
CAS:CHEMBRDG-BB 7118966 is an inhibitor of Bromodomain-containing protein 4 (human).Formula:C9H9BrN2OPurezza:99.28%Colore e forma:SolidPeso molecolare:241.08Ref: TM-T8609
1mg62,00€5mg123,00€10mg180,00€25mg298,00€50mg419,00€100mg567,00€200mg752,00€1mL*10mM (DMSO)113,00€Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Formula:C51H82O21Purezza:99.51% - 99.63%Colore e forma:SolidPeso molecolare:1031.18UNC1079
CAS:<p>UNC1079 is an selective L3MBTL3 domain inhibitor</p>Formula:C28H42N4O2Purezza:99.48%Colore e forma:SolidPeso molecolare:466.66Senaparib
CAS:Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.Formula:C24H20F2N6O3Purezza:99.8%Colore e forma:SolidPeso molecolare:478.45Ref: TM-T9593
1mg46,00€2mg59,00€5mg87,00€10mg153,00€25mg274,00€50mg432,00€100mg638,00€1mL*10mM (DMSO)96,00€O-304
CAS:O-304 is a pan-activator of AMP-activated protein kinase (AMPK).Formula:C16H11Cl2N3O2SPurezza:99.84% - ≥98%Colore e forma:SolidPeso molecolare:380.25Ref: TM-T7362
1mg66,00€2mg96,00€5mg144,00€10mg216,00€25mg432,00€50mg638,00€100mg908,00€500mg1.825,00€1mL*10mM (DMSO)159,00€WHI-P97 HCl
WHI-P97 HCl is a potent and selective JAK-3 inhibitor.Formula:C16H14Br2ClN3O3Purezza:99.49%Colore e forma:SolidPeso molecolare:491.56Ref: TM-T4657L
2mg37,00€5mg50,00€10mg90,00€25mg145,00€50mg192,00€100mg276,00€200mg393,00€1mL*10mM (DMSO)77,00€KDM4D-IN-1
CAS:KDM4D-IN-1 is a KDM4D inhibitor (IC50: 0.41±0.03 μM).Formula:C11H7N5OPurezza:99.51% - >99.99%Colore e forma:SolidPeso molecolare:225.21Ref: TM-T4214
1mg77,00€5mg166,00€10mg259,00€25mg522,00€50mg838,00€100mg1.225,00€1mL*10mM (DMSO)177,00€EPZ015666
CAS:EPZ015666 (GSK3235025) is an orally available inhibitor of PRMT5 enzymatic activity.Formula:C20H25N5O3Purezza:98% - 99.64%Colore e forma:SolidPeso molecolare:383.44PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purezza:97.58% - 99.94%Colore e forma:SolidPeso molecolare:419.48LLY-507
CAS:LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.Formula:C36H42N6OPurezza:99.58% - 99.93%Colore e forma:SolidPeso molecolare:574.76Ref: TM-T6879
1mg44,00€2mg55,00€5mg85,00€10mg138,00€25mg304,00€50mg552,00€100mg787,00€1mL*10mM (DMSO)110,00€UNC0646
CAS:UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP with low cellular toxicity.Formula:C36H59N7O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:621.93,6-Dihydroxyflavone
CAS:3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.Formula:C15H10O4Purezza:99.92%Colore e forma:SolidPeso molecolare:254.244-amino-1,8-Naphthalimide
CAS:4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nMFormula:C12H8N2O2Purezza:95.13%Colore e forma:Yellow Solid PowderPeso molecolare:212.2EX229
CAS:EX229 (C991) is an allosteric activator of AMPK, with Kds of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1, and α1β2γ1, respectively.Formula:C24H18ClN3O3Purezza:99.20% - 99.36%Colore e forma:SolidPeso molecolare:431.87Ref: TM-TQ0028
1mg37,00€2mg52,00€5mg74,00€10mg111,00€25mg221,00€50mg376,00€100mg565,00€1mL*10mM (DMSO)85,00€PFI-2 hydrochloride
CAS:PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM),Formula:C23H26ClF4N3O3SPurezza:99.31% - 99.91%Colore e forma:SolidPeso molecolare:535.98Ref: TM-T4583
1mg40,00€2mg51,00€5mg85,00€10mg117,00€25mg212,00€50mg378,00€100mg552,00€500mg1.169,00€1mL*10mM (DMSO)128,00€ML324
CAS:ML324(IC50=920 nM) is a specific inhibitor of jumonji histone demethylase (JMJD2).Formula:C21H23N3O2Purezza:98.22% - 98.57%Colore e forma:SolidPeso molecolare:349.43Ref: TM-T6593
2mg35,00€5mg51,00€10mg79,00€25mg128,00€50mg216,00€100mg354,00€200mg520,00€1mL*10mM (DMSO)84,00€Niraparib tosylate monohyrate
CAS:Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Formula:C26H30N4O5SPurezza:97.7% - 99.99%Colore e forma:SolidPeso molecolare:510.61Ref: TM-T9497
5mg60,00€10mg87,00€25mg117,00€50mg144,00€100mg216,00€200mg325,00€500mg545,00€1mL*10mM (DMSO)70,00€BMS-P5 free base
CAS:BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor.Formula:C27H32N6O2Purezza:99.88%Colore e forma:SolidPeso molecolare:472.58BAY 87-2243
CAS:BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).Formula:C26H26F3N7O2Purezza:98% - 99.95%Colore e forma:SolidPeso molecolare:525.53Ref: TM-T2488
1mg35,00€2mg43,00€5mg63,00€10mg101,00€25mg212,00€50mg351,00€100mg588,00€1mL*10mM (DMSO)73,00€ARN-3236
CAS:ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of <1 nM, 21.63 nM and 6.63 nMFormula:C19H16N2O2SPurezza:98.89% - 99.7%Colore e forma:SolidPeso molecolare:336.41Ref: TM-T5993
1mg60,00€5mg97,00€10mg160,00€25mg264,00€50mg354,00€100mg540,00€200mg777,00€1mL*10mM (DMSO)150,00€HNHA
CAS:HNHA is an inhibitor of HDAC.Formula:C17H21NO2SPurezza:98.04%Colore e forma:SolidPeso molecolare:303.42Ref: TM-T21806
1mg44,00€5mg84,00€10mg135,00€25mg279,00€50mg445,00€100mg640,00€200mg879,00€1mL*10mM (DMSO)90,00€IOX2
CAS:IOX2 is a selective HIF PHD inhibitor, active in cells with 21 nM IC50 for PHD2/ELGN-1, not inhibiting FIH at 20uM.Formula:C19H16N2O5Purezza:98% - 99.59%Colore e forma:SolidPeso molecolare:352.34URMC-099
CAS:URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Formula:C27H27N5Purezza:99.32% - 99.98%Colore e forma:SolidPeso molecolare:421.544-Phenylbutyric acid
CAS:4-Phenylbutyric acid (Benzenebutyric acid) is a HDAC inhibitor and an endoplasmic reticulum stress (ERS) inhibitor. Cost-effective and quality-assured.Formula:C10H12O2Purezza:98.40% - 99.76%Colore e forma:SolidPeso molecolare:164.2Eicosapentaenoic Acid sodium
CAS:EPA sodium, an oral omega-3, demethylates DNA, reactivates tumor suppressors, and induces vasodilation.Formula:C20H29NaO2Colore e forma:SolidPeso molecolare:324.43TIQ-A
CAS:TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.Formula:C11H7NOSPurezza:99.75%Colore e forma:SolidPeso molecolare:201.24Ref: TM-T50098
1mg50,00€5mg97,00€10mg170,00€25mg306,00€50mg437,00€100mg562,00€200mg777,00€1mL*10mM (DMSO)101,00€OTS186935 hydrochloride
OTS186935 HCl inhibits SUV39H2 (IC50 6.49 nM), curbs tumor growth in mice, and modulates γ-H2AX in cancer cells.Formula:C25H27Cl2N5O2Colore e forma:SolidPeso molecolare:522.31SAR-20347
CAS:SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).Formula:C21H18ClFN4O4Purezza:98.99% - 99.77%Colore e forma:SolidPeso molecolare:444.84Ref: TM-T4210
1mg35,00€5mg80,00€10mg116,00€25mg227,00€50mg354,00€100mg588,00€200mg818,00€1mL*10mM (DMSO)88,00€4'-Methoxychalcone
CAS:4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.Formula:C16H14O2Purezza:99.86%Colore e forma:SolidPeso molecolare:238.28NCGC00244536
CAS:NCGC00244536 (KDM4B Inhibitor B3) is a potent KDM4B inhibitor (IC50: 10 nM).Formula:C25H22N2O2Purezza:97.2% - 99.72%Colore e forma:SolidPeso molecolare:382.45Ref: TM-TQ0050
1mg96,00€5mg279,00€10mg472,00€25mg753,00€50mg1.074,00€100mg1.444,00€1mL*10mM (DMSO)240,00€Perindopril
CAS:Perindopril, an ACE inhibitor, treats hypertension, heart failure, and coronary artery disease; available as arginine or erbumine.Formula:C19H32N2O5Colore e forma:White PowderPeso molecolare:368.47Lomeguatrib
CAS:Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .Formula:C10H8BrN5OSPurezza:99.26% - >99.99%Colore e forma:SolidPeso molecolare:326.17FG-2216
CAS:FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.Formula:C12H9ClN2O4Purezza:97.1% - >99.99%Colore e forma:SolidPeso molecolare:280.66TG101209
CAS:TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Formula:C26H35N7O2SPurezza:99% - >99.99%Colore e forma:SolidPeso molecolare:509.67GSK-J1
CAS:GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively.Formula:C22H23N5O2Purezza:99.23% - 99.67%Colore e forma:SolidPeso molecolare:389.45BMS-P5
CAS:BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor.Formula:C27H33ClN6O2Purezza:99.88%Colore e forma:SolidPeso molecolare:509.04Ref: TM-T22277
2mg47,00€5mg90,00€10mg143,00€25mg283,00€50mg505,00€100mg802,00€200mg1.074,00€1mL*10mM (DMSO)92,00€GSK-J4 Hydrochloride
CAS:GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. It is an ethyl ester derivative of the GSK-J1.Formula:C24H28ClN5O2Purezza:97.95% - 98.23%Colore e forma:SolidPeso molecolare:453.97Ref: TM-T4383
1mg40,00€2mg52,00€5mg88,00€10mg127,00€25mg217,00€50mg363,00€100mg533,00€200mg745,00€1mL*10mM (DMSO)139,00€PJ34 hydrochloride
CAS:PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.Formula:C17H18ClN3O2Purezza:98.87% - ≥95%Colore e forma:SolidPeso molecolare:331.8
