Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2486 prodotti di "Cromatina/Epigenetica"
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Fedratinib hydrochloride hydrate
CAS:Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.Formula:C27H40Cl2N6O4SPurezza:98.96% - 99.87%Colore e forma:SolidPeso molecolare:615.61Rucaparib tartrate
CAS:Rucaparib tartrate: oral PARP-1/2/3 inhibitor, Ki=1.4 nM; also inhibits H6PD; for studying CRPC.Formula:C23H24FN3O7Colore e forma:SolidPeso molecolare:473.457PFI-3
CAS:PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.Formula:C19H19N3O2Purezza:99.58% - 99.94%Colore e forma:SolidPeso molecolare:321.37ME0328
CAS:ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.Formula:C19H19N3O2Purezza:99.22%Colore e forma:SolidPeso molecolare:321.37JNJ-42041935
CAS:JNJ-42041935 (HIF-PHD Inhibitor II) is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.Formula:C12H6ClF3N4O3Purezza:99.58% - ≥95%Colore e forma:SolidPeso molecolare:346.65Ref: TM-T3180
1mg40,00€2mg52,00€5mg88,00€10mg119,00€25mg210,00€50mg354,00€100mg567,00€500mg1.198,00€1mL*10mM (DMSO)87,00€UPF 1069
CAS:UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.Formula:C17H13NO3Purezza:98.80% - 99.88%Colore e forma:SolidPeso molecolare:279.29Windorphen
CAS:Windorphen is a Wnt inhibitor that selectively abrogates the Wnt signaling.Formula:C17H15ClO3Purezza:99.66%Colore e forma:SolidPeso molecolare:302.75UNC0642
CAS:UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM).Formula:C29H44F2N6O2Purezza:98.75% - 99.5%Colore e forma:SolidPeso molecolare:546.7Ref: TM-T4166
1mg38,00€2mg50,00€5mg82,00€10mg124,00€25mg219,00€50mg358,00€100mg537,00€200mg782,00€1mL*10mM (DMSO)89,00€HJ-PI01
CAS:<p>HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in triple-negative human breast cancer.</p>Formula:C14H11NO2Purezza:98.92%Colore e forma:SolidPeso molecolare:225.24GSK-J1
CAS:GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively.Formula:C22H23N5O2Purezza:99.23% - 99.67%Colore e forma:SolidPeso molecolare:389.45Chlorogenic Acid
CAS:Chlorogenic acid is a natural phenol. Chlorogenic acid has anti-inflammatory, antitumor, and antimicrobial effects. Cost-effective and quality-assured.Formula:C16H18O9Purezza:98.84% - 99.67%Colore e forma:SolidPeso molecolare:354.31Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Formula:C51H82O21Purezza:99.51% - 99.63%Colore e forma:SolidPeso molecolare:1031.18DL-α-Hydroxyglutaric acid disodium salt
CAS:DL-α-Hydroxyglutaric acid disodium salt (disodium 2-hydroxypentanedioate) is an α -hydroxyacid formed from the hydrolysis of (R) -5-oxy-2-tetrahydrofuranFormula:C5H6Na2O5Purezza:≥98%Colore e forma:SolidPeso molecolare:192.08AG490
CAS:AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.Formula:C17H14N2O3Purezza:98.6% - 99.85%Colore e forma:Yellow SolidPeso molecolare:294.3MK-3903
CAS:MK-3903 is a potent and selective AMPK activator (EC50: 8 nM).Formula:C27H19ClN2O3Purezza:98.63% - 99.75%Colore e forma:SolidPeso molecolare:454.9Ref: TM-T5187
1mg35,00€5mg80,00€10mg120,00€25mg188,00€50mg354,00€100mg588,00€200mg833,00€1mL*10mM (DMSO)88,00€PIN1 inhibitor API-1
CAS:API-1 is a Pin1 inhibitor (IC50: 72.3 nM), enhancing anticancer miRNA biogenesis and inhibiting hepatocellular carcinoma.Formula:C15H13F3N6O2Purezza:98.48%Colore e forma:SolidPeso molecolare:366.3Ref: TM-T16538
1mg60,00€5mg127,00€10mg235,00€25mg344,00€50mg512,00€100mg645,00€200mg898,00€500mg1.311,00€1mL*10mM (DMSO)140,00€BAZ1A-IN-1
CAS:BAZ1A-IN-1, a potent inhibitor, KD 0.52 μM against BAZ1A, is effective in high-BAZ1A cancer cells, not in low-BAZ1A ones.Formula:C16H12N4O3SPurezza:99.87%Colore e forma:SolidPeso molecolare:340.36Ref: TM-T9552
1mg88,00€5mg187,00€10mg283,00€25mg567,00€50mg848,00€100mg1.159,00€200mg1.549,00€1mL*10mM (DMSO)207,00€OG-L002
CAS:OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.Formula:C15H15NOPurezza:97.05% - 98.62%Colore e forma:SolidPeso molecolare:225.29GSK484 hydrochloride
CAS:GSK484 hydrochloride (GTPL8577) is a reversible peptidyl-arginine deiminase 4 (PAD4) inhibitor.Cost-effective and quality-assured.Formula:C27H32ClN5O3Purezza:98.32% - 99.62%Colore e forma:SolidPeso molecolare:510.03Ref: TM-TQ0067
1mg71,00€5mg147,00€10mg215,00€25mg435,00€50mg622,00€100mg887,00€1mL*10mM (DMSO)164,00€
