Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2442 prodotti di "Cromatina/Epigenetica"
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SP-146
SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).Formula:C25H20FN7OPurezza:97.82%Colore e forma:SolidPeso molecolare:453.47Ref: TM-T8685
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)177,00€Piribedil
CAS:Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.Formula:C16H18N4O2Purezza:99.79% - 99.82%Colore e forma:SolidPeso molecolare:298.34dBET1
CAS:dBET1 fuses (+)-JQ1 with thalidomide, degrades BET proteins via cereblon (EC50: 430 nM), and triggers apoptosis.Formula:C38H37ClN8O7SPurezza:98.02% - 99.3%Colore e forma:SolidPeso molecolare:785.27Ref: TM-T4495
1mg52,00€5mg104,00€10mg170,00€25mg283,00€50mg452,00€100mg687,00€200mg938,00€1mL*10mM (DMSO)154,00€ZM39923 hydrochloride
CAS:ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Formula:C23H25NO·HClPurezza:98.05%Colore e forma:SolidPeso molecolare:367.91MK-8745
CAS:<p>MK-8745 is a potent and selective Aurora A inhibitor.</p>Formula:C20H19ClFN5OSPurezza:99.09% - 99.79%Colore e forma:SolidPeso molecolare:431.91JANEX-1
CAS:JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.Formula:C16H15N3O3Purezza:98% - 99.81%Colore e forma:SolidPeso molecolare:297.31SGC2085
CAS:SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).Formula:C19H24N2O2Purezza:99.61% - 99.71%Colore e forma:SolidPeso molecolare:312.41Ref: TM-T7089
1mg88,00€2mg119,00€5mg227,00€10mg341,00€25mg563,00€50mg820,00€100mg1.130,00€1mL*10mM (DMSO)160,00€CPI-1205
CAS:CPI-1205 是一种高效的选择性 EZH2 抑制剂（IC50：0.002 μM，EC50：0.032 μM）。Formula:C27H33F3N4O3Purezza:98.71% - 99.7%Colore e forma:SolidPeso molecolare:518.57DCLX069
CAS:DCLX069: PRMT1 inhibitor, IC50=17.9µM, targets SAM pocket, inhibits breast/liver cancer, and AML cell growth.Formula:C20H25N3O2Purezza:97.76%Colore e forma:SolidPeso molecolare:339.43Ref: TM-T27133
1mg38,00€2mg49,00€5mg79,00€10mg111,00€25mg187,00€50mg305,00€100mg487,00€500mg1.035,00€1mL*10mM (DMSO)92,00€AZD5305
CAS:AZD5305 is a potent, selective and oral active PARP inhibitor.Formula:C22H26N6O2Purezza:98.68% - 99.93%Colore e forma:SolidPeso molecolare:406.48Ref: TM-T9165
1mg113,00€5mg235,00€10mg378,00€25mg630,00€50mg898,00€100mg1.216,00€1mL*10mM (DMSO)259,00€Peficitinib
CAS:Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.Formula:C18H22N4O2Purezza:98.67% - 99.4%Colore e forma:SolidPeso molecolare:326.39Ref: TM-T6933
2mg40,00€5mg66,00€10mg104,00€25mg182,00€50mg283,00€100mg439,00€200mg645,00€1mL*10mM (DMSO)73,00€E-7386
CAS:E-7386 is an oral active CBP/ -catenin modulator.Formula:C39H48FN9O4Purezza:98.92% - 99.91%Colore e forma:SolidPeso molecolare:725.85Ref: TM-T11136
1mg87,00€2mg135,00€5mg230,00€10mg376,00€25mg647,00€50mg920,00€100mg1.225,00€1mL*10mM (DMSO)369,00€Olaparib
CAS:View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.Formula:C24H23FN4O3Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:434.46TP-3654
CAS:TP-3654 is a second-generation Pim kinase inhibitor (Ki values against Pim-1/3: 5/42 nM).Formula:C22H25F3N4OPurezza:99.8% - 99.95%Colore e forma:SolidPeso molecolare:418.46E7449
CAS:E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.Formula:C18H15N5OPurezza:97.13%Colore e forma:SolidPeso molecolare:317.34Ref: TM-T4471
1mg35,00€5mg93,00€10mg120,00€25mg188,00€50mg284,00€100mg420,00€200mg622,00€1mL*10mM (DMSO)94,00€Protosappanin A
CAS:<p>Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.</p>Formula:C15H12O5Purezza:99.42% - 99.82%Colore e forma:SolidPeso molecolare:272.25Molibresib
CAS:Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).Formula:C22H22ClN5O2Purezza:97.70% - 99.08%Colore e forma:SolidPeso molecolare:423.9Ref: TM-T1906
1mg43,00€2mg57,00€5mg93,00€10mg125,00€25mg216,00€50mg359,00€100mg535,00€200mg752,00€500mg1.169,00€1mL*10mM (DMSO)93,00€(+)-JQ1 PA
CAS:(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM).Formula:C22H20ClN5OSPurezza:98.36%Colore e forma:SolidPeso molecolare:437.95WM-1119
CAS:WM-1119 is a highly potent, selective KAT6A/B inhibitorFormula:C18H13F2N3O3SPurezza:96.59% - 99.58%Colore e forma:SolidPeso molecolare:389.38XD14
CAS:<p>XD14 inhibits BET bromodomains with Kd: BRD4(1) 160nM, BRD2(1) 170nM, BRD3(1) 380nM, BRD3(2) 490nM, BRD2(2) 830nM, BRD4(2) 850nM.</p>Formula:C20H27N3O5SPurezza:97.46%Colore e forma:SolidPeso molecolare:421.51FL-411
CAS:FL-411 (BRD4-IN-1) is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for BRD4.Formula:C18H19N3O2SPurezza:98.19%Colore e forma:SolidPeso molecolare:341.43GSK3685032
CAS:<p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>Formula:C22H24N6OSPurezza:98.56% - 99.49%Colore e forma:SolidPeso molecolare:420.53Daminozide
CAS:Daminozide (Succinic Acid) is a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily.Formula:C6H12N2O3Purezza:99.86%Colore e forma:White Crystalline Solid Physical Description Odorless White Crystals Or Powder (Ntp 1992)Peso molecolare:160.17GSK-5959
CAS:GSK-5959 is a selective BRPF1 inhibitor with IC50 ~80 nM, 100-fold more specific than 35 other bromodomains.Formula:C22H26N4O3Purezza:98.35% - 98.65%Colore e forma:SolidPeso molecolare:394.47Deucravacitinib
CAS:Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.Formula:C20H19D3N8O3Purezza:98.52% - >99.99%Colore e forma:SolidPeso molecolare:425.46Ref: TM-T14687
1mg59,00€5mg144,00€10mg261,00€25mg410,00€50mg607,00€100mg863,00€1mL*10mM (DMSO)158,00€Momelotinib
CAS:Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.Formula:C23H22N6O2Purezza:97.07% - 99.56%Colore e forma:SolidPeso molecolare:414.46Ref: TM-T1849
1mg38,00€2mg49,00€5mg81,00€10mg95,00€25mg166,00€50mg259,00€100mg406,00€200mg625,00€1mL*10mM (DMSO)88,00€MS436
CAS:MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.Formula:C18H17N5O3SPurezza:97.95% - 98.92%Colore e forma:SolidPeso molecolare:383.42Ref: TM-T1854
2mg44,00€5mg65,00€10mg90,00€25mg175,00€50mg283,00€100mg452,00€200mg648,00€1mL*10mM (DMSO)72,00€SNS-314 Mesylate
CAS:SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.Formula:C18H15ClN6OS2·CH4O3SPurezza:99.44% - 99.92%Colore e forma:SolidPeso molecolare:527.04BAY-598
CAS:BAY 598 is a potent and selective competitive inhibitor of SMYD2, exhibiting >100-fold selectivity over SMYD3, SUV420H1, and SUV420H2. Cost-effective and quality-assured.Formula:C22H20Cl2F2N6O3Purezza:99.18% - 99.78%Colore e forma:SolidPeso molecolare:525.342',3',5'-triacetyl-5-Azacytidine
CAS:2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.Formula:C14H18N4O8Purezza:98.34%Colore e forma:SolidPeso molecolare:370.31Ref: TM-T7840
2mg40,00€5mg52,00€10mg80,00€25mg129,00€50mg187,00€100mg281,00€200mg406,00€1mL*10mM (DMSO)64,00€GSK046
CAS:GSK046 (iBET-BD2), potent oral BET BD2 inhibitor; IC50: BRD2 (264 nM), BRD3 (98 nM), BRD4 (49 nM), BRDT (214 nM); immunomodulatory.Formula:C23H27FN2O4Purezza:99.97%Colore e forma:SolidPeso molecolare:414.47Ref: TM-T8932
1mg60,00€5mg127,00€10mg212,00€25mg472,00€50mg755,00€100mg1.169,00€200mg1.568,00€1mL*10mM (DMSO)140,00€RO495
CAS:<p>RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assays</p>Formula:C17H14Cl2N6OPurezza:97.94%Colore e forma:SolidPeso molecolare:389.24GSK6853
CAS:GSK6853 is a potent, soluble, cell-active, and highly selective inhibitor of the BRPF1 bromodomain.Formula:C22H27N5O3Purezza:98.71% - 99.21%Colore e forma:SolidPeso molecolare:409.48(Z)-LFM-A13
CAS:(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.Formula:C11H8Br2N2O2Purezza:99.88%Colore e forma:SolidPeso molecolare:360Niraparib
CAS:Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.Formula:C19H20N4OPurezza:98% - 99.91%Colore e forma:SolidPeso molecolare:320.39Ref: TM-T3231
5mg60,00€10mg88,00€25mg111,00€50mg144,00€100mg216,00€200mg321,00€500mg543,00€1mL*10mM (DMSO)66,00€AKBA
CAS:<p>AKBA (3-O-Acetyl-11-keto-beta-boswellic acid), a natural component from frankincense, is a novel activator of Nrf2.</p>Formula:C32H48O5Purezza:97.85% - 99.77%Colore e forma:SolidPeso molecolare:512.72MN-64
CAS:MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.Formula:C18H16O2Purezza:99.5% - 99.93%Colore e forma:SolidPeso molecolare:264.32SGC0946
CAS:SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.Formula:C28H40BrN7O4Purezza:98% - 99.82%Colore e forma:SolidPeso molecolare:618.57SMI-16a
CAS:SMI-16a (PIM1/2 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (Formula:C13H13NO3SPurezza:99.99%Colore e forma:SolidPeso molecolare:263.31Ref: TM-T3989
1mg35,00€2mg48,00€5mg70,00€10mg87,00€25mg160,00€50mg235,00€100mg354,00€1mL*10mM (DMSO)92,00€OF-1
CAS:OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain.Formula:C17H18BrN3O4SPurezza:98.55% - ≥95%Colore e forma:SolidPeso molecolare:440.31Ref: TM-T2127
1mg38,00€5mg79,00€10mg130,00€25mg254,00€50mg406,00€100mg628,00€200mg879,00€1mL*10mM (DMSO)79,00€AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Formula:C19H23N7O2Purezza:99.83% - 99.98%Colore e forma:SolidPeso molecolare:381.43SETDB1-TTD-IN-1
CAS:SETDB1-TTD-IN-1 is a potent and selective inhibitor of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD, Kd = 88 nM).Cost-effective and quality-assured.Formula:C28H31N5O2Purezza:98.26% - 99.96%Colore e forma:SolidPeso molecolare:469.58JMJD7-IN-1
CAS:<p>JMJD7-IN-1 (Benzoic acid, 2,4-dichloro-, 5-nitro-8-quinolinyl ester) is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM.</p>Formula:C16H8Cl2N2O4Purezza:99.66%Colore e forma:SolidPeso molecolare:363.15PF-9366
CAS:PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).Formula:C20H19ClN4Purezza:97.28% - 99.88%Colore e forma:SolidPeso molecolare:350.84Ref: TM-T5191
1mg48,00€5mg92,00€10mg137,00€25mg240,00€50mg339,00€100mg465,00€200mg677,00€1mL*10mM (DMSO)97,00€AG-270
CAS:AG-270 is an allosteric and orally active inhibitor of MAT2A.Formula:C30H27N5O2Purezza:98.28% - 98.87%Colore e forma:SolidPeso molecolare:489.57Ref: TM-T9050
1mg110,00€2mgPrezzo su richiesta5mg256,00€10mg378,00€25mg628,00€50mg882,00€100mg1.225,00€200mg1.673,00€C-82
CAS:C-82 is a specific CBP/β-catenin antagonist. It inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300.Formula:C33H34N6O4Purezza:98.86% - 99.66%Colore e forma:SolidPeso molecolare:578.66Itacitinib
CAS:<p>Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.</p>Formula:C26H23F4N9OPurezza:96.4% - 99.5%Colore e forma:SolidPeso molecolare:553.51A-966492
CAS:A-96649 is a new-type and effective inhibitor. The Ki of A-966492 for PARP1 and PARP2 is 1 nM and 1.5 nM, respectively.Formula:C18H17FN4OPurezza:98.53% - 99.27%Colore e forma:SolidPeso molecolare:324.35Ref: TM-T6366
2mg35,00€5mg50,00€10mg89,00€25mg172,00€50mg275,00€100mg394,00€200mg560,00€1mL*10mM (DMSO)56,00€GSK503
CAS:GSK-503, a potent EZH2 inhibitor, has potential antitumor activity.Formula:C31H38N6O2Purezza:98% - 99.89%Colore e forma:SolidPeso molecolare:526.67PFI-4
CAS:PFI-4 is a potent and selective and cell-permeable BRPF1 bromodomain inhibitor.Formula:C21H24N4O3Purezza:99.53% - ≥95%Colore e forma:SolidPeso molecolare:380.44NI-57
CAS:NI-57 inhibits BRPF family proteins: BRPF1 (IC50=3.1nM), BRPF2 (IC50=46nM), BRPF3 (IC50=140nM).Formula:C19H17N3O4SPurezza:99.88% - >99.99%Colore e forma:SolidPeso molecolare:383.42Menin-MLL inhibitor MI-2
CAS:Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.Formula:C18H25N5S2Purezza:97.46%Colore e forma:SolidPeso molecolare:375.55Ref: TM-T2649
2mg42,00€5mg62,00€10mg88,00€25mg169,00€50mg243,00€100mg376,00€200mg550,00€1mL*10mM (DMSO)67,00€Molibresib besylate
CAS:Molibresib besylate (GSK 525762C) is a BET protein family inhibitor used in the study of refractory hematologic malignant diseases.Formula:C28H28ClN5O5SPurezza:99.64% - 99.64%Colore e forma:SolidPeso molecolare:582.07Oroxylin A
CAS:Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.Formula:C16H12O5Purezza:98.72% - 99.55%Colore e forma:SolidPeso molecolare:284.26Ref: TM-T6S1315
1mg39,00€5mg74,00€10mg96,00€25mg156,00€50mg220,00€100mg325,00€200mg472,00€1mL*10mM (DMSO)88,00€Tofacitinib
CAS:Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.Formula:C16H20N6OPurezza:99% - >99.99%Colore e forma:SolidPeso molecolare:312.37GSK126
CAS:GSK126 (GSK2816126A) is a excellently specific EZH2 methyltransferase inhibitor ( IC50=9.9 nM).Formula:C31H38N6O2Purezza:98% - 99.67%Colore e forma:SolidPeso molecolare:526.67Ref: TM-T2079
2mg44,00€5mg65,00€10mg88,00€25mg152,00€50mg227,00€100mg349,00€200mg455,00€1mL*10mM (DMSO)74,00€Seclidemstat
CAS:Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM.Formula:C20H23ClN4O4SPurezza:98.28% - 99.76%Colore e forma:SolidPeso molecolare:450.94Ref: TM-T4527
5mg48,00€10mg72,00€25mg120,00€50mg187,00€100mg354,00€200mg528,00€500mg852,00€1mL*10mM (DMSO)49,00€Veliparib dihydrochloride
CAS:Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.Formula:C13H18Cl2N4OPurezza:98% - 99.81%Colore e forma:SolidPeso molecolare:317.21Remodelin
CAS:Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10.Formula:C15H14N4SPurezza:99.39% - 99.83%Colore e forma:SolidPeso molecolare:282.363Ref: TM-T3499
2mg39,00€5mg55,00€10mg77,00€25mg130,00€50mg185,00€100mg250,00€200mg373,00€1mL*10mM (DMSO)59,00€PT-2385
CAS:PT-2385 is a selective HIF-2α inhibitor (Kd<50 nM).Formula:C17H12F3NO4SPurezza:98.91% - 99.55%Colore e forma:SolidPeso molecolare:383.34Ref: TM-T7848
1mg66,00€2mg87,00€5mg153,00€10mg235,00€25mg399,00€50mg562,00€100mg782,00€200mg1.035,00€1mL*10mM (DMSO)126,00€Venadaparib
CAS:Venadaparib, a PARP inhibitor (IC50: 1.4/1.0 nM for PARP1/2), is orally active, selective, not affecting PARP-5, used in tumor studies.Formula:C23H23FN4O2Purezza:99.86%Colore e forma:SolidPeso molecolare:406.45Ref: TM-T9430
1mg48,00€2mg63,00€5mg96,00€10mg144,00€25mg283,00€50mg464,00€100mg680,00€1mL*10mM (DMSO)96,00€RN-1 dihydrochloride
CAS:RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM).Formula:C23H31Cl2N3O2Purezza:99.64%Colore e forma:SolidPeso molecolare:452.42Ruxolitinib
CAS:<p>Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.</p>Formula:C17H18N6Purezza:99.4% - >99.99%Colore e forma:SolidPeso molecolare:306.36GSK2801
CAS:GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.Formula:C20H21NO4SPurezza:97.78% - 99.45%Colore e forma:SolidPeso molecolare:371.455-Methyl-2'-deoxycytidine
CAS:5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.Formula:C10H15N3O4Purezza:99.18% - 99.69%Colore e forma:SolidPeso molecolare:241.242-methyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one
CAS:2-methyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one is ligand of CBP.Formula:C10H11NOSPurezza:99.68%Colore e forma:SolidPeso molecolare:193.275-Fluoro-2'-deoxycytidine
CAS:5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .Formula:C9H12FN3O4Purezza:97.91%Colore e forma:Fine White PowderPeso molecolare:245.21Ref: TM-T7718
2mg35,00€5mg50,00€10mg67,00€25mg96,00€50mg145,00€100mg210,00€200mg313,00€500mg525,00€1mL*10mM (DMSO)52,00€A-366
CAS:A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.Formula:C19H27N3O2Purezza:97.28% - 99.8%Colore e forma:SolidPeso molecolare:329.44Ref: TM-T3624
1mg35,00€2mg50,00€5mg74,00€10mg90,00€25mg208,00€50mg359,00€100mg530,00€1mL*10mM (DMSO)82,00€UNC3866 TFA(1872382-47-2 free base)
CAS:UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.Formula:C45H67F3N6O10Purezza:98.43%Colore e forma:SolidPeso molecolare:909.046-Thioguanine
CAS:6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Formula:C5H5N5SPurezza:98.75% - >99.99%Colore e forma:Odorless Or Almost Odorless Pale Yellow Crystalline PowderPeso molecolare:167.19IOX4
CAS:IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)Formula:C15H16N6O3Purezza:99.97%Colore e forma:SolidPeso molecolare:328.33NEO2734
CAS:NEO2734 (EP31670) is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).Formula:C22H24F3N3O3Purezza:98.72% - 98.8%Colore e forma:SolidPeso molecolare:435.44Ref: TM-T8658
1mg114,00€5mg274,00€10mg454,00€25mg750,00€50mg1.026,00€100mg1.406,00€500mg2.822,00€1mL*10mM (DMSO)303,00€GSK343
CAS:GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity againstFormula:C31H39N7O2Purezza:98% - 99.9%Colore e forma:SolidPeso molecolare:541.69Panaxadiol
CAS:Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.Formula:C30H52O3Purezza:98% - 99.9%Colore e forma:SolidPeso molecolare:460.73XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Formula:C22H31N9OPurezza:99.07%Colore e forma:SolidPeso molecolare:437.54Ref: TM-T17267
1mg56,00€2mg78,00€5mg99,00€10mg149,00€25mg258,00€50mg393,00€100mg582,00€1mL*10mM (DMSO)110,00€Tozasertib
CAS:Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Formula:C23H28N8OSPurezza:99.99%Colore e forma:SolidPeso molecolare:464.591-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one
CAS:1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one is an inhibitor Bromodomain-containing protein 4 (human).Formula:C17H19NOPurezza:99.08%Colore e forma:SolidPeso molecolare:253.34Ref: TM-T8601
1mg62,00€5mg123,00€10mg180,00€25mg298,00€50mg419,00€100mg567,00€200mg752,00€1mL*10mM (DMSO)115,00€GSK620
CAS:<p>GSK620, a selective pan-BD2 inhibitor, has anti-inflammatory properties and favorable oral pharmacokinetics.</p>Formula:C18H19N3O3Purezza:99.42% - 99.88%Colore e forma:SolidPeso molecolare:325.36Talazoparib
CAS:Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).Formula:C19H14F2N6OPurezza:97.02% - 99.92%Colore e forma:SolidPeso molecolare:380.35Ref: TM-T6253
2mg42,00€5mg62,00€10mg88,00€25mg135,00€50mg187,00€100mg311,00€200mg429,00€500mg697,00€1mL*10mM (DMSO)67,00€Solcitinib
CAS:<p>Solcitinib (GLPG-0778), a JAK1 inhibitor, may treat psoriasis, ulcerative colitis, and lupus.</p>Formula:C22H23N5O2Purezza:99.61% - 99.82%Colore e forma:SolidPeso molecolare:389.45Dbet57
CAS:dBET57: PROTAC-based BRD4BD1 degrader, DC50/5h at 500 nM, ineffective on BRD4BD2.Formula:C34H31ClN8O5SPurezza:99.36% - 99.52%Colore e forma:SolidPeso molecolare:699.18Ref: TM-T5440
1mg49,00€5mg97,00€10mg156,00€25mg279,00€50mg432,00€100mg625,00€500mg1.293,00€1mL*10mM (DMSO)170,00€MAT2A inhibitor 4
CAS:MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancerFormula:C16H15ClFNPurezza:99.17%Colore e forma:SolidPeso molecolare:275.75Ref: TM-T9262
1mg40,00€5mg90,00€10mg131,00€25mg220,00€50mg314,00€100mg426,00€200mg575,00€1mL*10mM (DMSO)89,00€Mivebresib
CAS:Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.Formula:C22H19F2N3O4SPurezza:98.74% - 99.32%Colore e forma:SolidPeso molecolare:459.47Ref: TM-T3712
1mg58,00€2mg82,00€5mg97,00€10mg159,00€25mg256,00€50mg462,00€100mg660,00€1mL*10mM (DMSO)99,00€PHA-680632
CAS:<p>PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.</p>Formula:C28H35N7O2Purezza:98.2%Colore e forma:SolidPeso molecolare:501.623-Aminobenzamide
CAS:3-Aminobenzamide (PARP-IN-1) is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction duringFormula:C7H8N2OPurezza:98.4% - 99.5%Colore e forma:White To Off-White PowderPeso molecolare:136.15SF2523
CAS:SF2523 is a highly selective and potent inhibitor.Formula:C19H17NO5SPurezza:99.1% - 99.51%Colore e forma:SolidPeso molecolare:371.41Ref: TM-T3986
1mg37,00€5mg79,00€10mg119,00€25mg274,00€50mg432,00€100mg638,00€500mg1.359,00€1mL*10mM (DMSO)87,00€JNJ-64619178
CAS:JNJ-64619178: selective, oral, pseudo-irreversible PRMT5 inhibitor (IC50: 0.14 nM), effective in lung cancer.Formula:C22H23BrN6O2Purezza:98.86% - 99.98%Colore e forma:SolidPeso molecolare:483.36Ref: TM-T15624
1mg88,00€5mg170,00€10mg274,00€25mg567,00€50mg944,00€100mg1.659,00€1mL*10mM (DMSO)182,00€GeA-69
CAS:<p>GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).</p>Formula:C20H16N2OPurezza:99.85%Colore e forma:SolidPeso molecolare:300.35TTK21
CAS:<p>TTK21 is an activator of CBP/p300 histone acetyltransferase activity.</p>Formula:C17H15ClF3NO2Purezza:98.43%Colore e forma:SolidPeso molecolare:357.75PX-478
CAS:PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.Formula:C13H20Cl4N2O3Purezza:97% - 99.79%Colore e forma:SolidPeso molecolare:394.12Ref: TM-T6961
1mg42,00€5mg88,00€10mg137,00€25mg205,00€50mg276,00€100mg434,00€200mg638,00€1mL*10mM (DMSO)88,00€LW6
CAS:LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.Formula:C26H29NO5Purezza:98.1% - 98.22%Colore e forma:SolidPeso molecolare:435.51Ref: TM-T3494
2mg47,00€5mg69,00€10mg89,00€25mg183,00€50mg298,00€100mg449,00€500mg938,00€1mL*10mM (DMSO)69,00€Ref: TM-T5S2358
1mg52,00€2mg72,00€5mg111,00€10mg144,00€25mg207,00€50mg311,00€100mg472,00€1mL*10mM (DMSO)123,00€Belzutifan
CAS:"Belzutifan (MK-6482) is an oral HIF-2α inhibitor for ccRCC, with enhanced potency (IC50: 9 nM)."Formula:C17H12F3NO4SPurezza:99.34% - 99.88%Colore e forma:SolidPeso molecolare:383.34Ref: TM-T16679
1mg70,00€5mg153,00€10mg216,00€25mg411,00€50mg660,00€100mg938,00€200mg1.264,00€1mL*10mM (DMSO)166,00€I-BET151
CAS:I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 μM, in cell-free assays).Formula:C23H21N5O3Purezza:97.34% - 99.63%Colore e forma:SolidPeso molecolare:415.44Ref: TM-T2120
1mg48,00€2mg65,00€5mg96,00€10mg115,00€25mg202,00€50mg339,00€100mg507,00€500mg1.130,00€1mL*10mM (DMSO)105,00€Veliparib
CAS:Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.Formula:C13H16N4OPurezza:98.66% - 99%Colore e forma:SolidPeso molecolare:244.29Ref: TM-T2591
5mg57,00€10mg81,00€25mg127,00€50mg207,00€100mg331,00€200mg540,00€500mg852,00€1mL*10mM (DMSO)64,00€Tranylcypromine hemisulfate
CAS:Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset ofFormula:C9H11N1H2SO4Purezza:98% - 99.96%Colore e forma:SolidPeso molecolare:182.23SGI-1027
CAS:SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).Formula:C27H23N7OPurezza:99.45% - 99.78%Colore e forma:SolidPeso molecolare:461.52Ref: TM-T1904
5mg58,00€10mg94,00€25mg163,00€50mg296,00€100mg467,00€500mg1.035,00€1mL*10mM (DMSO)74,00€GSK467
CAS:GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).Formula:C17H13N5O2Purezza:99.55% - 99.85%Colore e forma:SolidPeso molecolare:319.32MG 149
CAS:MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).Formula:C22H28O3Purezza:98.69% - 99.86%Colore e forma:SolidPeso molecolare:340.46Ref: TM-T6584
1mg52,00€2mg74,00€5mg96,00€10mg170,00€25mg324,00€50mg518,00€100mg747,00€1mL*10mM (DMSO)114,00€UNC3866
CAS:UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.Formula:C43H66N6O8Purezza:88.06% - 99.62%Colore e forma:SolidPeso molecolare:795.02GW779439X
CAS:GW779439X is an inhibitor of CDK.Formula:C22H21F3N8Purezza:97.87%Colore e forma:SolidPeso molecolare:454.45Ref: TM-T8866
1mg62,00€2mg87,00€5mg119,00€10mg188,00€25mg425,00€50mg625,00€100mg892,00€1mL*10mM (DMSO)131,00€CCT241736
CAS:CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Formula:C22H23Cl2N7Purezza:96.2% - 99.81%Colore e forma:SolidPeso molecolare:456.37G244-LM
CAS:G244-LM is a potent and specific inhibitor of tankyrase 1/2. G244-LM inhibits Wnt signaling.Formula:C18H22N4O3S2Purezza:98.46%Colore e forma:SolidPeso molecolare:406.52AMG 900
CAS:AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.Formula:C28H21N7OSPurezza:98.4% - 99.51%Colore e forma:SolidPeso molecolare:503.58Ref: TM-T6380
1mg52,00€5mg97,00€10mg166,00€25mg303,00€50mg467,00€100mg682,00€500mg1.415,00€1mL*10mM (DMSO)105,00€3-Methoxybenzamide
CAS:3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.Formula:C8H9NO2Purezza:98.52%Colore e forma:SolidPeso molecolare:151.16Amifostine trihydrate
CAS:Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.Formula:C5H15N2O3PS·3H2OPurezza:99.71% - 99.80%Colore e forma:SolidPeso molecolare:268.27Fosifidancitinib
CAS:Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3.Formula:C21H21FN5O7PPurezza:99.54%Colore e forma:SolidPeso molecolare:505.39Ref: TM-T38624
1mg87,00€2mg124,00€5mg187,00€10mg284,00€25mg452,00€50mg645,00€100mg867,00€200mg1.159,00€ARV-771
CAS:ARV-771 is an effective BET degrader based on PROTAC technology.Cost-effective and quality-assured.Formula:C49H60ClN9O7S2Purezza:99.69%Colore e forma:SolidPeso molecolare:986.64Ref: TM-T5435
1mg60,00€5mg119,00€10mg187,00€25mg374,00€50mg550,00€100mg772,00€200mg1.026,00€1mL*10mM (DMSO)202,00€Oclacitinib maleate
CAS:Oclacitinib maleate is a selective JAK inhibitor (IC50: 10-99 nM; JAK1 cytokines: 36-249 nM), with no effect on 38 non-JAK kinases.Formula:C15H23N5O2S·C4H4O4Purezza:99.17% - 99.92%Colore e forma:SolidPeso molecolare:453.51Ref: TM-T6914
1mg39,00€2mg50,00€5mg79,00€10mg99,00€25mg170,00€50mg271,00€100mg457,00€1mL*10mM (DMSO)86,00€CPI-169 racemate
CAS:<p>CPI-169 racemate (CPI 169) is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.</p>Formula:C27H36N4O5SPurezza:99.59%Colore e forma:SolidPeso molecolare:528.66BET bromodomain inhibitor
CAS:BET bromodomain inhibitor is a potent BET inhibitor.Formula:C24H20ClN5O2Purezza:98.22% - 99.85%Colore e forma:SolidPeso molecolare:445.9Ref: TM-T2072
1mg38,00€2mg49,00€5mg80,00€10mg120,00€25mg197,00€50mg279,00€100mg439,00€1mL*10mM (DMSO)88,00€BIX-01294 trihydrochloride
CAS:BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.Formula:C28H38N6O2·3HClPurezza:99.41% - 99.95%Colore e forma:SolidPeso molecolare:600.02Ref: TM-T1959
2mg52,00€5mg71,00€10mg107,00€25mg192,00€50mg274,00€100mg472,00€200mg642,00€1mL*10mM (DMSO)111,00€ENMD-2076
CAS:ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formula:C21H25N7Purezza:97.63% - ≥95%Colore e forma:SolidPeso molecolare:375.47(Z)-SMI-4a
CAS:(Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM.Formula:C11H6F3NO2SPurezza:97.66% - 99.93%Colore e forma:SolidPeso molecolare:273.23Oclacitinib
CAS:Oclacitinib (PF-03394197)(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000Formula:C15H23N5O2SPurezza:98% - 98.45%Colore e forma:White To Off-White SolidPeso molecolare:337.44lutidinic acid
CAS:<p>lutidinic acid (2,4-Dicarboxypyridine) is an in vitro and in cell inhibitor, as well as a known inhibitor of the histone lysine demethylases.</p>Formula:C7H5NO4Purezza:98.06%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:167.12RG108
CAS:RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).Formula:C19H14N2O4Purezza:98% - 99.43%Colore e forma:SolidPeso molecolare:334.33Ref: TM-T2038
5mg47,00€10mg69,00€25mg117,00€50mg205,00€100mg286,00€200mg401,00€500mg652,00€1mL*10mM (DMSO)56,00€SGC-CBP30
CAS:SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).Formula:C28H33ClN4O3Purezza:99.05% - >99.99%Colore e forma:SolidPeso molecolare:509.04Ref: TM-T6668
1mg49,00€2mg71,00€5mg88,00€10mg119,00€25mg210,00€50mg354,00€100mg528,00€1mL*10mM (DMSO)88,00€AZD-1480
CAS:<p>AZD1480: JAK2 inhibitor, IC50 0.26 nM; selective vs Tyk2, JAK3; less on JAK1. Used in solid tumors, PPV, PMF, ET trials.</p>Formula:C14H14ClFN8Purezza:98.25% - 99.47%Colore e forma:SolidPeso molecolare:348.77JAK-IN-5 hydrochloride
CAS:JAK-IN-5 hydrochloride is a JAK inhibitor [1].Formula:C27H32ClFN6OColore e forma:SolidPeso molecolare:511.03Barasertib-HQPA
CAS:<p>Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.</p>Formula:C26H30FN7O3Purezza:98.43% - 99.29%Colore e forma:SolidPeso molecolare:507.56ARV-825
CAS:ARV-825: PROTAC recruits BRD4 to cereblon for rapid BRD4 degradation in all tested BL cells.Formula:C46H47ClN8O9SPurezza:97.15% - 98%Colore e forma:SolidPeso molecolare:923.43UNC6934
CAS:UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.Formula:C24H21N5O4Purezza:98.67%Colore e forma:SolidPeso molecolare:443.45Ref: TM-T9584
1mg49,00€5mg97,00€10mg160,00€25mg344,00€50mg512,00€100mg707,00€200mg938,00€1mL*10mM (DMSO)106,00€Annaosanchun
CAS:Annaosanchun (YC-6) is potentially for the treatment of acute ischemic stroke (AIS).Formula:C19H32O3Purezza:99.58%Colore e forma:SolidPeso molecolare:308.46(S)-HH2853
CAS:(S)-HH2853 is a potent EZH1/2 inhibitor, aromatic, <100 nM IC50 for EZH2_Y641F, promising for anti-tumor/autoimmune research.Formula:C31H36F3N7O3Purezza:97.18% - 99.74%Colore e forma:SolidPeso molecolare:611.66MRK-740
CAS:MRK-740 is a PRDM9 histone methyltransferase inhibitor that inhibits H3K4 methylation.Formula:C25H32N6O3Purezza:99.66%Colore e forma:SolidPeso molecolare:464.56MS023 dihydrochloride
CAS:MS023 dihydrochloride (MS023 2HCl) is a human type I protein arginine methyltransferase inhibitor with antitumour activity for the study of breast cancer.Formula:C17H27Cl2N3OPurezza:99.52%Colore e forma:SolidPeso molecolare:360.32Cerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Formula:C20H28ClN7O3SPurezza:99.85%Colore e forma:SolidPeso molecolare:482Zavondemstat
CAS:Zavondemstat (QC8222 free base) is a KDM4 inhibitor with anticancer and antitumor activity for the study of triple-negative and breast cancers.Formula:C26H29N3O3Purezza:99.43% - 99.53%Colore e forma:SolidPeso molecolare:431.53MIV-6R
CAS:MIV-6R inhibits Menin-MLL interaction (IC50: 56 nM) and can be used to study leukemia.Formula:C27H35N3OPurezza:99.81% - 99.88%Colore e forma:SolidPeso molecolare:417.59TNG-462
CAS:TNG-462 is a oral, potent and selective PRMT5 inhibitor for the treatment of MTAP-deficient and/or MTA-accumulating cancers (e.g., pancreatic & bladder).Formula:C28H36N6O2SPurezza:98.7%Colore e forma:SolidPeso molecolare:520.69Ref: TM-T79873
1mg156,00€5mg269,00€10mg404,00€25mg607,00€50mg912,00€100mg1.378,00€200mg1.853,00€1mL*10mM (DMSO)309,00€BI-9321 trihydrochloride
CAS:BI-9321 trihydrochloride (BI9321 trihydrochloride) is an NSD3-PWWP1 antagonist that downregulates Myc messenger RNA expression.Formula:C22H24Cl3FN4Purezza:99.12% - 99.34%Colore e forma:SolidPeso molecolare:469.81GS-829845
CAS:GS-829845 is a JAK1 inhibitor, the main component of the active metabolite of Filgotinib, which is approximately 10-fold less potent and has a longer half-lifeFormula:C17H19N5O2SPurezza:99.93%Colore e forma:SolidPeso molecolare:357.43CX-6258 hydrochloride
CAS:CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 nM).Formula:C26H24ClN3O3·HClPurezza:96.03% - 98.60%Colore e forma:SolidPeso molecolare:498.4Ref: TM-T6148
1mg43,00€5mg88,00€10mg127,00€25mg235,00€50mg376,00€100mg567,00€200mg805,00€1mL*10mM (DMSO)87,00€Chromium(III) acetate
CAS:Chromium(III) acetate （Chromium acetate） is a small molecule ionic crosslinker that is used as a feedstock for the synthesis of other compounds.Formula:C2H3O2CrPurezza:99.9%Colore e forma:Blue-Green Powder Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment It Is Used InPeso molecolare:76.37Osunprotafib
CAS:Osunprotafib (ABBV-CLS-484) is a potent, orally bioavailable PTP1B/PTPN2 inhibitor in clinical trials for solid tumors.Cost-effective and quality-assured.Formula:C17H24FN3O4SPurezza:97.11% - 99.91%Colore e forma:SolidPeso molecolare:385.45Talazoparib tosylate
CAS:PF-3882845 is an MR antagonist that binds to the progesterone receptor (PR) and is used in the study of endocrine disorders and urogenital disorders.Formula:C26H22F2N6O4SPurezza:99.79%Colore e forma:SolidPeso molecolare:552.55Ref: TM-T16979
2mg42,00€5mg62,00€10mg88,00€25mg135,00€50mg188,00€100mg311,00€200mg432,00€1mL*10mM (DMSO)74,00€CBHcy
CAS:CBHcy, a dual substrate analog, is a specific BHMT inhibitor that may induce cysteinemia.Formula:C9H17NO4SPurezza:>99.99% - >99.99%Colore e forma:SolidPeso molecolare:235.3PFI-2
CAS:PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over otherFormula:C23H25F4N3O3SPurezza:99.38%Colore e forma:SolidPeso molecolare:499.52Ref: TM-T1987
1mgPrezzo su richiesta2mg58,00€5mg90,00€10mg129,00€25mg240,00€50mg416,00€100mg658,00€200mgPrezzo su richiestaR 59-022
CAS:R 59-022 (DKGI-I) is a DGK inhibitor and a 5-HT Receptor antagonist that blocks filovirus internalization in host cells.Formula:C27H26FN3OSPurezza:98.55%Colore e forma:SolidPeso molecolare:459.58Ref: TM-T16709
1mg38,00€5mg79,00€10mg126,00€25mg284,00€50mg472,00€100mg775,00€200mg1.026,00€1mL*10mM (DMSO)80,00€MK-5108
CAS:MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Formula:C22H21ClFN3O3SPurezza:99.22%Colore e forma:SolidPeso molecolare:461.94NVP-BSK805
CAS:NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.Formula:C27H28F2N6OPurezza:98%Colore e forma:SolidPeso molecolare:490.55Dehydrocorydaline nitrate
CAS:DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Formula:C22H24N2O7Purezza:99.79% - 99.92%Colore e forma:SolidPeso molecolare:428.44Ref: TM-T2S2362
1mg94,00€5mg216,00€10mg354,00€25mg582,00€50mg825,00€100mg1.111,00€200mg1.491,00€1mL*10mM (DMSO)255,00€SCH-1473759 hydrochloride
CAS:SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Formula:C20H27ClN8OSPurezza:98.29%Colore e forma:SolidPeso molecolare:463Ref: TM-T12864
2mg361,00€5mgPrezzo su richiesta10mgPrezzo su richiesta1mL*10mM (DMSO)Prezzo su richiestaGSK2807 Trifluoroacetate
CAS:GSK2807 Trifluoroacetate is a selective and SAM-competitive inhibitor of SMYD3 (Ki: 14 nM; IC50: 130 nM).Formula:C21H33F3N8O7Purezza:99.95%Colore e forma:SolidPeso molecolare:566.53Diethyl bipy55'DC
CAS:<p>"Diethyl bipy55'DC blocks CP4H, crucial for collagen stability via hydroxylation in cells."</p>Formula:C16H16N2O4Purezza:98%Colore e forma:SolidPeso molecolare:300.312-PADQZ
CAS:DPQ is an antiviral compound.Formula:C14H19N5O2Purezza:98%Colore e forma:White PowderPeso molecolare:289.33Tazemetostat trihydrochloride
CAS:Tazemetostat trihydrochloride, an EZH2 inhibitor, orally active, IC50: 4nM (rat), Ki: 2.5nM (human), effective in peptide and nucleosome assays.Formula:C34H47Cl3N4O4Purezza:98%Colore e forma:SolidPeso molecolare:682.12TETi76
CAS:TETi76 is an orally active inhibitor from the TET family, demonstrating IC50 values of 1.5, 9.4, and 8.8 μM against TET1, TET2, and TET3, respectively. The compound competitively binds to the active sites of TET enzymes, reducing cytosine hydroxymethylation and restricting clonal growth in mutated TET2 in vitro and in vivo, without affecting the growth of normal hematopoietic progenitor cells. TETi76 is utilized in leukemia research.Formula:C10H16O5Colore e forma:SolidPeso molecolare:216.23(R)-Dihydrolipoic acid
CAS:(R)-Dihydrolipoic acid, the biochemically significant R-enantiomer, partakes in biochemical transformations.Formula:C8H16O2S2Purezza:98%Colore e forma:SolidPeso molecolare:208.33Acedapsone
CAS:Acedapsone has antimalarial and antimicrobial action, but is mainly used as a depot leprostatic agent.Formula:C16H16N2O4SPurezza:98%Colore e forma:SolidPeso molecolare:332.37GSK 4027
CAS:GSK 4027 is a PCAF/GCN5 bromodomain chemical probe. In a time-resolved fluorescence resonance energy transfer (TR-FRET) assay, it has a pIC50 of 7.4±0.11 for PCAF.Formula:C17H21BrN4OColore e forma:SolidPeso molecolare:377.28Nicotinamide-d4
CAS:Nicotinamide-d4 is a deuterium-labelled compound of nicotinamide for isotope tracing. Nicotinamide, a vitamin B3 derivative, inhibits SIRT1 and SIRT2.Formula:C6H2D4N2OPurezza:99.746%Colore e forma:SolidPeso molecolare:126.15193 D7
CAS:193 D7 is an inhibitor of histone demethylase JMJD1C (IC50= 0.59 μM in in vitro demethylation assay). In vivo, 193 D7 suppresses tumors by targeting intratumoral Treg cells in mouse tumor models.Formula:C16H15NO4SColore e forma:SolidPeso molecolare:317.36BG14
CAS:BG14: High-res optical epigenetic control; photo-inhibits human histone deacetylases with visible light.Formula:C21H21N5OColore e forma:SolidPeso molecolare:359.433BChE/HDAC6-IN-2
CAS:BChE/HDAC6-IN-2 is an inhibitor of BChE and HDAC6 with neuroprotective and ROS scavenging activity and a metal ion co-agonist and inhibits tau phosphorylation.Formula:C27H30N4O4Purezza:98.47%Colore e forma:SoildPeso molecolare:474.55BG47
CAS:BG47: a COMET probe for precise optical epigenetic control, inhibits histone deacetylases with light.Formula:C25H22N4O2SColore e forma:SolidPeso molecolare:442.54CrBKA
CAS:CrBKA is a fluorogenic small-molecule substrate of SIRT6 with weak activity [1] .Formula:C28H31N3O6Colore e forma:SolidPeso molecolare:505.56HDAC6-IN-27
CAS:HDAC6-IN-27 (compound 8C), an HDAC inhibitor, exhibits IC 50 values of 15.9 nM, 136.5 nM, and 6180.2 nM against HDAC6, HDAC8, and HDAC1, respectively. It also demonstrates potent antiparasitic effects [1].Formula:C15H15N3O4Colore e forma:SolidPeso molecolare:301.3KAT6-IN-1
CAS:KAT6-IN-1 (compound E) is a selective, orally available inhibitor of histone acetyltransferases KAT6A and KAT6B, exhibiting antitumour activity for cancer.Formula:C19H18N4O5SPurezza:99.86%Colore e forma:SolidPeso molecolare:414.43AdipoR agonist 1
CAS:AdipoR agonist 1 (Compound 112254), acting as an agonist for the adiponectin receptor (AdipoR), stimulates transcriptional regulators including peroxisome proliferator-activated receptors (PPARs), peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α), sirtuin 1 (SIRT1), and adenylate-activated protein kinase (AMPK). It is employed in the field of preventive doping research.Formula:C26H35N3O3Colore e forma:SolidPeso molecolare:437.57BG48
CAS:BG48, a COMET probe, enables precise optical epigenetic control and photochromically blocks human histone deacetylases with visible light.Formula:C25H23N5OSColore e forma:SolidPeso molecolare:441.55GSK-J1 lithium salt
CAS:GSK-J1 lithium salt is an effective inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with an IC 50 of 60 nM for KDM6B.Formula:C22H22LiN5O2Purezza:98%Colore e forma:SolidPeso molecolare:395.38Guanosine-5'-triphosphate disodium salt
CAS:5'-GTP disodium salt boosts myogenic differentiation and fuels cellular processes.Formula:C10H14N5Na2O14P3Purezza:95.69% - 99.96%Colore e forma:Odorless White SolidPeso molecolare:567.14Asteltoxin
CAS:Asteltoxin is a useful organic compound for research related to life sciences. The catalog number is T124203 and the CAS number is 79663-49-3.Formula:C23H30O7Colore e forma:SolidPeso molecolare:418.486KR-39038
CAS:KR-39038 is an oral GRK5 inhibitor for heart failure research; blocks HDAC5 pathway, IC50: 0.02 μM, fights cardiac hypertrophy.Formula:C24H32ClFN6OColore e forma:SolidPeso molecolare:475.00I-BET787
CAS:I-BET787, an orally active pan-BET bromodomain inhibitor, has demonstrated efficacy in murine inflammation models.Formula:C16H20ClN3O2Colore e forma:SolidPeso molecolare:321.80ZM39923
CAS:ZM39923 is a JAK3 inhibitor (pIC50: 7.1). ZM39923 also effectively inhibits tissue transglutaminase (IC50: 10 nM).Formula:C23H25NOPurezza:98%Colore e forma:SolidPeso molecolare:331.45HDAC2-IN-2
CAS:HDAC2-IN-2 (compound 124) acts as an HDAC2 inhibitor, exhibiting a Kd value ranging from 0.1-1 μM.Formula:C18H15N3O3SColore e forma:SolidPeso molecolare:353.40(3S,4S)-Tofacitinib
CAS:(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.Formula:C16H20N6OPurezza:98%Colore e forma:SolidPeso molecolare:312.37TAK-285
CAS:TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Formula:C26H25ClF3N5O3Purezza:99.73%Colore e forma:SolidPeso molecolare:547.96Ref: TM-T6039
1mg38,00€5mg80,00€10mg120,00€25mg216,00€50mg354,00€100mg512,00€200mg727,00€1mL*10mM (DMSO)96,00€TMPA
CAS:TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.Formula:C21H32O6Purezza:99.21%Colore e forma:SolidPeso molecolare:380.48Ref: TM-T13173
1mg80,00€5mg167,00€10mg274,00€25mg465,00€50mg655,00€100mg1.017,00€1mL*10mM (DMSO)170,00€E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Formula:C21H30O6Purezza:99.52%Colore e forma:SolidPeso molecolare:378.46MY-1B
CAS:MY-1B is a nitrogen-substituted butenamide stereoprobe that blocks stereoselective enrichment of NSUN2, binding selectively to the C271 of NSUN2.Formula:C22H18BrN3O2Purezza:99.81% - >99.99%Colore e forma:SoildPeso molecolare:436.3UNC0224
CAS:UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.Formula:C26H43N7O2Purezza:99.80%Colore e forma:SolidPeso molecolare:485.67Ref: TM-T17203
1mg51,00€2mg73,00€5mg97,00€10mg159,00€25mg354,00€50mg558,00€100mg797,00€500mg1.634,00€1mL*10mM (DMSO)107,00€GW843682X
CAS:GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).Formula:C22H18F3N3O4SPurezza:99.92%Colore e forma:SolidPeso molecolare:477.46GSK-1268997
CAS:GSK-1268997 is a bio-active chemical.Formula:C21H23N7O3SPurezza:99.33% - 99.81%Colore e forma:SolidPeso molecolare:453.52Y02224
CAS:Y02224 is a BET inhibitor. It shows the reasonable antiproliferative effect on leukemia cells.Formula:C20H17BrN2O4SPurezza:98%Colore e forma:SolidPeso molecolare:461.33RET-IN-19
CAS:RET-IN-19, a potent RET inhibitor, anticancer: IC50 6.8 nM (RET-wt), 13.51 nM (RET V804M); for NSCLC research.Formula:C28H28N6O4SColore e forma:SolidPeso molecolare:544.62Dot1L-IN-5
CAS:Dot1L-IN-5 is a potent inhibitor of the disruptor of telomeric silencing 1-like protein ( DOT1L ) with an IC 50 SPA DOT1L of 0.17 nM [1].Formula:C23H19ClF2N8O5SColore e forma:SolidPeso molecolare:592.96Y08284
CAS:Y08284: selective CBP bromodomain inhibitor, IC50: 4.21 nM, oral. Halts prostate cancer cell growth; anti-tumor.Formula:C26H25FN4O4Colore e forma:SolidPeso molecolare:476.5PI3K/Akt/CREB activator 1
CAS:<p>PI3K/Akt/CREB activator 1 (AE-18) is an iNOS inhibitor that can be used to study vascular dementia and Parkinson's.</p>Formula:C19H15F4NO3Colore e forma:SolidPeso molecolare:381.32Helenalin Acetate
CAS:Helenalin Acetate: anti-inflammatory, anti-cancer, hinders C/EBPß and p300 cooperation.Formula:C17H20O5Purezza:98%Colore e forma:SolidPeso molecolare:304.34HDAC-IN-45
CAS:HDAC-IN-45, a small HDAC blocker, forms H-bonds with Y303 and shows anticancer properties; IC50 for HDAC1/2/3: 0.108/0.585/0.563 μM.Formula:C25H20ClFN8OColore e forma:SolidPeso molecolare:502.93DM-01
CAS:<p>DM-01 is a potent and selective inhibitor of EZH2.</p>Formula:C23H24F3N3O2Colore e forma:SolidPeso molecolare:431.45JAK-IN-10
CAS:<p>JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye disorders.</p>Formula:C20H18FN5O3SPurezza:99.53%Colore e forma:SolidPeso molecolare:427.45dBRD9-A
CAS:Potent BRD9 degrader that binds selectively, fully degrades BRD9 at low doses, and hinders synovial sarcoma growth in vitro and in mice.Formula:C42H49N7O8Colore e forma:SolidPeso molecolare:779.88(1S,2R)-Tranylcypromine hydrochloride
CAS:(1S,2R)-Tranylcypromine hydrochloride ((1S,2R)-SKF 385), a potent antidepressant, functions by inhibiting both MAO and LSD1.Formula:C9H12ClNColore e forma:SolidPeso molecolare:169.651PB118
PB118 clears Aβ, boosts phagocytosis, enhances tubulin networks, reduces p-tau & inflammation in AD; HDAC6 IC50: 5.6 nM.Formula:C18H19FN2O2Colore e forma:SoildPeso molecolare:314.35PNZ5
CAS:PNZ5, an isoxazole-based pan-BET inhibitor, demonstrates potent activity and high selectivity comparable to the established (+)-JQ1, exhibiting a dissociationFormula:C20H18N2O2Purezza:99.51% - 99.61%Colore e forma:SolidPeso molecolare:318.37Ref: TM-T12513
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€200mg1.444,00€1mL*10mM (DMSO)253,00€JAK3-IN-1
CAS:JAK3-IN-1 is an orally active, selective and potent JAK3 inhibitor for the study of immune system disorders.Formula:C26H30ClN7O2Colore e forma:SolidPeso molecolare:508.02Gue1654
CAS:Gue1654 is an OXE-R inhibitor and cardiomyocyte apoptosis.Gue1654 can be used for the study of cardiovascular diseases.Formula:C23H17N3OS3Purezza:98.02% - 98.04%Colore e forma:SolidPeso molecolare:447.6LSD1-IN-6
CAS:LSD1-IN-6, a potent LSD1 inhibitor (IC50: 123 nM), enhances H3K4me2 without altering LSD1 expression. Reversible.Formula:C15H13BrN2O3Purezza:98%Colore e forma:SolidPeso molecolare:349.18PARP-1/2-IN-1
CAS:PARP-1-/2-IN-1 is a potent inhibitor of PARP-1 (IC50: 0.51 nM) and PARP-2 (IC50: 23.11 nM).Formula:C24H27FN4O3Colore e forma:SolidPeso molecolare:438.49SMYD2-IN-1
CAS:SMYD2-IN-1 is an inhibitor of SMYD2 (IC50 of 4.45 nM).Formula:C25H25Cl2F2N7O2Purezza:98%Colore e forma:SolidPeso molecolare:564.41HDAC3-IN-T326
CAS:HDAC3-IN-T326: potent, selective HDAC3 inhibitor, boosts NF-κB acetylation, activates latent HIV gene expression.Formula:C21H18N6O3SPurezza:98%Colore e forma:SolidPeso molecolare:434.47PS432
CAS:PS432 inhibits atypical PKCs, targets PIF-pocket, reduces tumors in mice sans side effects.Formula:C25H19ClN2O5SPurezza:98%Colore e forma:SolidPeso molecolare:494.95MAT2A-IN-4
CAS:MAT2A-IN-4 can be used for the cancer research that is an inhibitor of methionine adenosyltransferase 2A (MAT2A)[1].Formula:C18H16ClN3OColore e forma:SolidPeso molecolare:325.79Akt Inhibitor X
CAS:Akt Inhibitor X is a cell-permeable and reversible inhibitor of Akt phosphorylation.Formula:C20H25ClN2OPurezza:98%Colore e forma:SolidPeso molecolare:344.88NSC-636819
CAS:NSC-636819 is a novel inhibitor of KDM4A/KDM4B.Formula:C22H12Cl4N2O4Purezza:98%Colore e forma:SolidPeso molecolare:510.15
