Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2442 prodotti di "Cromatina/Epigenetica"
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CID-4785700
CAS:CID-4785700 is a potent pan-GTPase inhibitor that inhibits Rab7 and inhibits the fungal histone acetyltransferase Rtt109 that binds to Asf1 and Vps75Formula:C22H23ClFN3O3Purezza:98.16%Colore e forma:SolidPeso molecolare:431.89Ref: TM-T71740
1mg333,00€5mg922,00€10mg1.140,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.664,00€Kgp-IN-1
CAS:Kgp-IN-1 is an arginine-specific gingipain (Rgp) inhibitor.Formula:C19H24F4N4O3Purezza:98%Colore e forma:SolidPeso molecolare:432.41HIF-PHD-IN-2
CAS:HIF-PHD-IN-2 (compound 25) is a highly effective PHD inhibitor, displaying IC50 values below 100 nM for PHD1, PHD2, and PHD3 [1].Formula:C17H15N5O3SColore e forma:SolidPeso molecolare:369.4Rucaparib camsylate
CAS:Rucaparib camsylate, a PARP-1, -2, -3 inhibitor (Ki=1.4 nM for PARP-1) & H6PD blocker, may treat resistant prostate cancer.Formula:C19H18FN3O·xC10H16O4SColore e forma:SolidDepudecin
CAS:Depudecin, a polyketide from Alternaria brassicicola, has an 11-carbon chain with two epoxides and six stereocenters, inhibits HDAC, and is anti-angiogenic.Formula:C11H16O4Colore e forma:SolidPeso molecolare:212.24PRMT5-IN-10
CAS:PRMT5-IN-10 exhibits promising structure-dependent inhibitory effect on the protein methyltransferase PRMT5:MEP50 complex.Formula:C13H17N5O4Colore e forma:SolidPeso molecolare:307.31AMPK activator 8
CAS:AMPK activator 8 targets rAMPK α1β1γ1/α2β1γ1/α1β2γ1 (EC50: 11/27/4 nM) for type 2 diabetes research.Formula:C25H21ClN2O6Colore e forma:SolidPeso molecolare:480.9CBP/p300-IN-10
CAS:CBP/p300-IN-10, potent EP300/CREBBP inhibitor; IC50: 26 nM/39 nM. Potential for cancer research.Formula:C25H24F5N5O3Colore e forma:SolidPeso molecolare:537.48ST7710AA1
CAS:ST7710AA1 inhibits PARP-1, effectively targets in vitro, and overcomes Pgp-associated multidrug resistance.Formula:C20H22N4OColore e forma:SolidPeso molecolare:334.41WD2000-012547
CAS:WD2000-012547 is a selective inhibitor of poly(ADP-ribose)-polymerase (PARP-1) (pKi: 8.221).Formula:C17H14N2OPurezza:98%Colore e forma:SolidPeso molecolare:262.31SIRT5 inhibitor 4
CAS:SIRT5 inhibitor 4 (compound 11) is a dose-dependent and selective SIRT5 (Sirtuin5) inhibitorand no inhibitory effect on SIRT1/2/3,anticancer.Formula:C18H15N3O4SPurezza:99.97%Colore e forma:SolidPeso molecolare:369.39K00135
CAS:K00135 (IMIDAZOPYRIDAZIN 1) is a selective inhibitor of Pim kinases and can be used in studies about gastric cancer and antileukemic therapeutics.Formula:C18H18N4OPurezza:98.16%Colore e forma:SolidPeso molecolare:306.36CK2/PIM1-IN-1
CAS:CK2/PIM1-IN-1 inhibits CK2 & PIM1 (IC50s: 3.787 & 4.327 μM), aimed for cancer research.Formula:C15H9NO4S2Purezza:98%Colore e forma:SolidPeso molecolare:331.37LT052
CAS:LT052 is a BET BD1 inhibitor with anti-inflammatory activity. It mediates the BRD4/NF-κB/NLRP3 signaling inflammatory pathway.Formula:C22H19N5O4SPurezza:98.82%Colore e forma:SolidPeso molecolare:449.48PF-00956980
CAS:PF-00956980: reversible JAK inhibitor, IC50: JAK1 (2.2μM), JAK2 (23.1μM), JAK3 (59.9μM), for lung/skin inflammation research.Formula:C18H26N6OColore e forma:SolidPeso molecolare:342.44EZH2-IN-3
CAS:EZH2-IN-3 is an inhibitor of EZH2 and EZH1 with selective impact on diffuse large B cell lymphoma cell growth.Formula:C27H28ClN5O2Purezza:98%Colore e forma:SolidPeso molecolare:490KDM2/7-IN-1
CAS:KDM2/7-IN-1 is a selective histone demethylase inhibitor (IC50s: 0.2–>120 μM) that inhibits HeLa and KYSE-150 cell proliferation, epigenetic and cancer.Formula:C15H27NO4Purezza:99.87%Colore e forma:SolidPeso molecolare:285.38Lorpucitinib
CAS:Lorpucitinib (JNJ-64251330) is a JAK kinase inhibitor used in the study of inflammatory and gastrointestinal diseases.Formula:C22H28N6O2Purezza:99.72%Colore e forma:SolidPeso molecolare:408.5MT477
CAS:MT477 inhibits PKC-α, impairs Ras/ERK1/2 phosphorylation, induces apoptosis, and reduces proliferation in various cancer cells.Formula:C31H30N2O12S3Colore e forma:SolidPeso molecolare:718.77SIRT5 inhibitor 6
CAS:SIRT5 inhibitor 6 is Sirtuin 5 inhibitor for sepsis-associated acute kidney injury (AKI) modulates protein succinylation and pro-inflammatory cytokine release.Formula:C21H28N6O4SPurezza:99.84%Colore e forma:SolidPeso molecolare:460.55BRM/BRG1 ATP Inhibitor-4
CAS:BRM/BRG1 ATP Inhibitor-4, a potent inhibitor of BRG1/BRM, is utilized in the research of cancers and BAF complex-related disorders.Formula:C25H32N6O3SColore e forma:SolidPeso molecolare:496.62BRD4884
CAS:BRD4884 is a highly selective and efficient HDAC1 and HDAC2 inhibitor that also inhibits HDAC3, used in research on neurological disorders.Formula:C18H19FN2O2Purezza:99.19% - 99.21%Colore e forma:SolidPeso molecolare:314.35DPQ
CAS:<p>DPQ inhibits PARP-1, aids in neuroprotection, restores ATP, and lessens neuronal injury from NMDA.</p>Formula:C18H26N2O2Purezza:98%Colore e forma:SolidPeso molecolare:302.41ZLD2218
CAS:ZLD2218, a potent inhibitor of BRD4 with an IC50 value of 107 nM, has been demonstrated to mitigate kidney injury and fibrosis through extensive studies.Formula:C22H18N4OColore e forma:SolidPeso molecolare:354.4CPI-1612
CAS:CPI-1612: Oral EP300/CBP HAT inhibitor, IC50 8.1 nM, has anticancer properties.Formula:C27H26N6OColore e forma:SolidPeso molecolare:450.53GPI-15427
CAS:GPI-15427: a potent PARP-1 inhibitor, crosses the blood-brain barrier, boosts TMZ's effects on CNS tumors, and sensitizes cancer to radiotherapy.Formula:C20H20N4O2Colore e forma:SolidPeso molecolare:348.4EZM 2302
CAS:EZM 2302 (GSK3359088) is a selective, and orally available arginine methyltransferase CARM1 inhibitor (IC50: 6 nM).Cost-effective and quality-assured.Formula:C29H37ClN6O5Purezza:97.47% - ≥98%Colore e forma:SolidPeso molecolare:585.09PIM1-IN-6
CAS:PIM1-IN-6 (5h) inhibits PIM-1 (IC50: 0.60 μM) and is cytotoxic to HCT-116 (IC50: 1.51 μM) and MCF-7 cells (IC50: 15.2 μM).Formula:C21H18N6O4Colore e forma:SolidPeso molecolare:418.41Aurora kinase inhibitor-10
CAS:Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.Formula:C21H19F5N6O4SColore e forma:SolidPeso molecolare:546.47SGC6870
CAS:SGC6870 is a novel potent, selective, and cell-active inhibitor of PRMT6 with IC50 of 77 ± 6 nM, being selective over all other PRMTs and 23 methyltransferases.Formula:C23H21BrN2O2SColore e forma:SolidPeso molecolare:469.39A2AAR/HDAC-IN-2
CAS:A2AAR/HDAC-IN-2: potent dual A2AAR/HDAC inhib., Ki 10.3 nM, IC50 18.5 nM, anti-tumor potential.Formula:C23H26N6O4Colore e forma:SolidPeso molecolare:450.49HDAC-IN-29
CAS:HDAC-IN-29 (compound 13b) is a potent pan- HDAC inhibitor with antitumor activity.Formula:C20H23N3O4SColore e forma:SolidPeso molecolare:401.48DCE_42
CAS:DCE_42 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.Formula:C22H19N9O2SPurezza:98%Colore e forma:SolidPeso molecolare:473.51Tankyrase-IN-4
Tankyrase-IN-4 is a potent inhibitor of tankyrase 1 (TNKS1), exhibiting an IC50 of 0.8 nM, and is utilized in cancer research.Formula:C25H24N6O5Colore e forma:SolidPeso molecolare:488.5PF-739
CAS:PF-739 is an AMPK agonist that has been shown to activate AMPK in hepatocytes and skeletal muscle.Formula:C23H23ClN2O5Purezza:98%Colore e forma:SolidPeso molecolare:442.89DS-437
CAS:DS-437 is a dual PRMT5/7 inhibitor (IC50s: 6 μM). DS-437 also inhibits DNMT3A and DNMT3B (IC50s: 52 and 62 μM). DS-437 inhibits the methylation of FOXP3.Formula:C15H23N7O4SPurezza:98%Colore e forma:SolidPeso molecolare:397.45KBH-A42
CAS:KBH-A42 is an inhibitor of histone deacetylase.Formula:C17H22N2O3Purezza:98%Colore e forma:SolidPeso molecolare:302.37CCT077791
CAS:CCT077791 is a potent inhibitor of p300 and PCAF histone acetyltransferase activity for cancer research.Formula:C9H5ClN2O3SPurezza:98.60%Colore e forma:SolidPeso molecolare:256.67MI-1
CAS:MI-1 inhibits Menin-MLL interaction with an IC 50 of 1.9 μM [1].Formula:C19H25N5S2Colore e forma:SolidPeso molecolare:387.57MAT2A-IN-7
CAS:MAT2A-IN-7 inhibits MAT2A in various cancers, especially MTAP-deficient cancer cells, with potential for research use.Formula:C17H13ClF3N3O2Colore e forma:SolidPeso molecolare:383.75ART-IN-1
CAS:ART-IN-1 (compound 7) is a selective inhibitor of PARP with IC 50 s of 19, 22, 2.4, >100, 1.1 μM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively [1].Formula:C14H13NO2SColore e forma:SolidPeso molecolare:259.32Piribedil dihydrochloride
CAS:dopamine agonistFormula:C16H20Cl2N4O2Purezza:98%Colore e forma:SolidPeso molecolare:371.26HIF-1α-IN-3
CAS:<p>HIF-1α-IN-3, also known as Compound (S)-3f, is a hypoxia-selective inhibitor of HIF-1α. It exhibits potent antiestrogenic activity [1].</p>Formula:C19H17N5O2Colore e forma:SolidPeso molecolare:347.37HDAC6/8/BRPF1-IN-1
CAS:HDAC6/8/BRPF1-IN-1 is a cancer-research inhibitor for HDAC6, HDAC8, BRPF1 with IC50: 344-908 nM and Kd: 175.2 nM.Formula:C18H17N3O5SColore e forma:SolidPeso molecolare:387.41EML741
CAS:<p>EML741 also inhibits DNMT1 (IC50, 3.1 μM), with no effect on DNMT3a or DNMT3b.</p>Formula:C31H49N5O2Purezza:98%Colore e forma:SolidPeso molecolare:523.75MicroRNA-21-IN-2
CAS:MicroRNA-21-IN-2 is a potential miR-21 inhibitor with an AC50 value of 3.29 μM. MicroRNA-21-IN-2 can be used to study cancer.Formula:C17H15N3O3SPurezza:99.45%Colore e forma:SolidPeso molecolare:341.38JAK-IN-18
CAS:"JAK-IN-18: potent JAK inhibitor for eye, skin, respiratory disease research (WO2018204238A1, comp 1)."Formula:C27H28F2N6O3Colore e forma:SolidPeso molecolare:522.55Setin-1
CAS:Setin-1 is the most potent Set7 inhibitor that acts by inhibiting the KMTase G9a.Formula:C29H21F3N2O2Purezza:98%Colore e forma:SolidPeso molecolare:486.48GSK 525768A
CAS:GSK 525768A, the inactive enantiomer of GSK525762A, exhibits no activity towards BET.Formula:C22H22ClN5O2Colore e forma:SolidPeso molecolare:423.9OXFBD03
CAS:OXFBD03 is the bromodomain and extra terminal domain bromodomain family member BRD4(1) inhibitor.Formula:C20H19NO4Purezza:98%Colore e forma:SolidPeso molecolare:337.37LY 170198
CAS:LY 170198 is a protein kinase C inhibitor.Formula:C22H25N5O5Purezza:98%Colore e forma:SolidPeso molecolare:439.46BRD4 Inhibitor-26
BRD4 Inhibitor-26: blocks BRD4 (BD1 and BD2) with IC50 of 0.82 μM & 1.94 μM; used in ovarian cancer research.Formula:C29H27N5O6SColore e forma:SolidPeso molecolare:573.62DHPCC-9
CAS:DHPCC-9 is an inhibitor of Pim kinase.Formula:C15H10N2OColore e forma:SolidPeso molecolare:234.25DC_501
CAS:DC_501 is a selective non-nucleoside DNA methyltransferase 1 inhibitor.Formula:C25H23Cl2N3OPurezza:98%Colore e forma:SolidPeso molecolare:452.38DCE_254
CAS:DCE_254 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.Formula:C21H17N9OSPurezza:98%Colore e forma:SolidPeso molecolare:443.48Langkamide
CAS:Langkamide is a HIF-2 inhibitor with EC₅₀ values of 14.0 uM.Formula:C16H17NO5Purezza:98%Colore e forma:SolidPeso molecolare:303.31Dot1L-IN-7
CAS:Dot1L-IN-7 (compound 25), a potent DOT1L inhibitor with an IC50 of 1.0 μM, selectively kills MLL-AF9, sparing E2A-HLF cells.Formula:C23H27N9O2Colore e forma:SolidPeso molecolare:461.526-Methyl-5-azacytidine
CAS:6-Methyl-5-azacytidine is a potent DNMT inhibitor.Formula:C9H14N4O5Purezza:98%Colore e forma:SolidPeso molecolare:258.23BF1
CAS:BF1 is an inhibitor of HAT (histone acetyltransferase) active both in vitro and in vivo.Formula:C12H12ClN3SColore e forma:SolidPeso molecolare:265.76Farnesylthiotriazole
CAS:Farnesylthiotriazole is a persistent PKC activator agent.Formula:C17H27N3SPurezza:98%Colore e forma:SolidPeso molecolare:305.48Tenovin-D3
CAS:Tenovin-D3 is a sirtuin SirT2 inhibitor. It acts by increasing p21 (CDKN1A) expression in a p53-independent manner.Formula:C22H27Cl3N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:533.9ML399
CAS:ML399 inhibits menin–MLL interaction, selectively blocking oncogenic MLL signaling in leukemia cells, supporting functional genomics and therapeutic research.Formula:C27H28FN3O2Purezza:97.84% - 98.20%Colore e forma:SolidPeso molecolare:445.53Ref: TM-T24484
1mgPrezzo su richiesta5mg730,00€10mgPrezzo su richiesta25mg1.539,00€50mg1.941,00€100mg2.451,00€150mg2.565,00€NVS-BET-1
CAS:NVS-BET-1 is a BET bromodomain inhibitor. NVS-BET-1 can regulate keratinocyte plasticity.Formula:C22H21ClN4O2Colore e forma:SolidPeso molecolare:408.88HIF-IN-33
CAS:HIF-IN-33 is an inhibitor of HIF pathway.Formula:C21H17F3N4O2Purezza:98%Colore e forma:SolidPeso molecolare:414.38TP-238
CAS:"TP-238: Potent CECR2/BPTF dual probe; IC50: 30 nM/350 nM. Inhibits BRD9 (pIC50: 5.9); minimal activity on 338 other kinases."Formula:C22H30N6O3SColore e forma:SolidPeso molecolare:458.58BET-BAY 002
CAS:BET-BAY 002 is an effective BET bromodomain inhibitor demonstrating efficacy in vivo and in vitro against multiple myeloma and leukaemia models.Formula:C22H18ClN5OColore e forma:SolidPeso molecolare:403.86Fagaronine chloride
CAS:Fagaronine chloride is a potent inhibitor of Topoisomerases I.Formula:C21H20ClNO4Colore e forma:SolidPeso molecolare:385.84Lobelane Hydrochloride
CAS:Lobelane Hydrochloride is a vesicular monoamine transporter-2 (VMAT2) inhibitor.Formula:C22H30ClNColore e forma:SolidPeso molecolare:343.93SirReal-1
CAS:SirReal-1 is an effective and selective inhibitor of Sirt2.Formula:C18H18N4OS2Purezza:98%Colore e forma:SolidPeso molecolare:370.49Prospasmine
CAS:Prospasmine is an anticholinergic.Formula:C17H28ClNO2Purezza:98%Colore e forma:SolidPeso molecolare:313.87BRD4-BD1-IN-1
CAS:BRD4-BD1-IN-1 (Compound 9a) is a BRD4-BD1 inhibitor(IC50= 38.20 μM).Formula:C16H15BrN4O4Colore e forma:SolidPeso molecolare:407.22Hns 32
CAS:Hns 32 possesses antiarrhythmic properties in dog and guinea pig hearts. It also has vasodilator action.Formula:C24H29N3Purezza:98%Colore e forma:SolidPeso molecolare:359.51PI3K/HDAC-IN-1
CAS:<p>PI3K/HDAC-IN-1 is a potent PI3K and HDAC dual inhibitor(IC50s of 8.1 nM and 1.4 nM, respectively).</p>Formula:C22H25FN4O4Purezza:98%Colore e forma:SolidPeso molecolare:428.46INCB054329 Racemate
CAS:INCB054329 Racemate is an inhibitor of BET protein.Formula:C19H16N4O3Purezza:98%Colore e forma:SolidPeso molecolare:348.36BRD4 Inhibitor-19
CAS:BRD4 inhibitors -19 are BET inhibitors that act on BRD4-BD1 (IC50: 55 nM) and can be used to study multiple myeloma.Formula:C29H25N5O3Colore e forma:SolidPeso molecolare:491.54CBHA
CAS:m-Carboxycinnamic bishydroxamide: HDAC inhibitor, ID50 = 10 nM (HDAC1), 70 nM (HDAC3), induces apoptosis and tumor growth suppression.Formula:C10H10N2O4Colore e forma:SolidPeso molecolare:222.2TK4g
CAS:TK4g, a potent JAK inhibitor, has IC50s of 12.61 nM (JAK2) & 15.80 nM (JAK3); promising for lymphoid diseases & leukemia research.Formula:C19H19N3O4SColore e forma:SolidPeso molecolare:385.44NSC-311068
CAS:NSC-311068: A selective TET1 inhibitor, reducing 5hmC and AML cell viability with high TET1.Formula:C10H6N4O4SColore e forma:SolidPeso molecolare:278.24TyK2-IN-2
CAS:TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).Formula:C16H18N6OPurezza:98%Colore e forma:SolidPeso molecolare:310.35ABT-472
CAS:ABT-472 is a novel PARP inhibitorFormula:C20H28N4O5Colore e forma:SolidPeso molecolare:404.46GSK926
CAS:GSK926 is a selective, SAM-competitive, and cell-active EZH2 inhibitor.Formula:C29H35N7O2Colore e forma:SolidPeso molecolare:513.63YUKA1
CAS:YUKA1, a cell-permeable KDM5A inhibitor with a weak effect on KDM5C, increase H3K4me3 and inhibit the proliferation, prevent drug-resistant.Formula:C13H16N4O2SPurezza:99.85%Colore e forma:SolidPeso molecolare:292.36Ref: TM-T17278
1mg111,00€5mg264,00€10mg432,00€25mg847,00€50mg1.293,00€100mg1.882,00€200mg2.593,00€1mL*10mM (DMSO)283,00€CREBBP-IN-9
CAS:CREBBP-IN-9, a CREBBP inhibitor, acts on the bromodomain of the protein.Formula:C16H15N5O2SPurezza:98%Colore e forma:SolidPeso molecolare:341.39CP-690550A
CAS:Cp-690550a is a novel JAK3 inhibitor, which is used to treat rheumatoid arthritis, graft rejection, psoriasis, and other immune-mediated diseases.Formula:C15H21N5O2Colore e forma:SolidPeso molecolare:303.36SDR-04
CAS:SDR-04 inhibits BRD4-BD1 with high affinity, suppressing MV4;11 cancer cell growth as a BET inhibitor.Formula:C19H16N4O2Colore e forma:SolidPeso molecolare:332.36H8-A5
CAS:H8-A5, a HDAC8 inhibitor, shows antiproliferation activity in MDA-MB-231 cancer cells.Formula:C14H9F3N2O2SPurezza:98%Colore e forma:SolidPeso molecolare:326.29CPI703
CAS:CPI703 is a novel potent and specific CBP/EP300 bromodomain inhibitor.Formula:C17H22N4OPurezza:98%Colore e forma:SolidPeso molecolare:298.38PARP1-IN-11
CAS:PARP1-IN-11 is a potent PARP1 inhibitor (IC50=0.082 μM), also reducing PARP3, TNKS1, and TNKS2 activity.Formula:C16H12N2O4Colore e forma:SolidPeso molecolare:296.28KDM2B-IN-3
CAS:KDM2B-IN-3, from patent WO2016112284A1 as compound 183c, potently inhibits histone demethylase KDM2B, with cancer research potential.Formula:C25H30N2O2Colore e forma:SolidPeso molecolare:390.52Arazine
CAS:Arazine, a cell-permeable G protein modulator, is an isoprenylcysteine methyltransferase substrate.Formula:C20H33NO3SPurezza:90%Colore e forma:SolidPeso molecolare:367.55UNC2327
CAS:UNC2327 is a potent and selective inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50:230 nM).Formula:C14H17N5O2SPurezza:98%Colore e forma:SolidPeso molecolare:319.38OHM1
CAS:OHM1, an analog of HIF1α CTAD, effectively inhibits the interaction between HIF1α CTAD and p300/CBP by targeting the CH1 domain with a binding affinity of 0.53Formula:C24H42N6O5Colore e forma:SolidPeso molecolare:494.63MS453
CAS:MS453 is a potent and selective SETD8 inhibitor with an IC50 value of 804 nM.Formula:C20H27N5O3Colore e forma:SolidPeso molecolare:385.46ARTD10/PARP10-IN-2
CAS:ARTD10/PARP10-IN-2: A potent, non-selective PARP inhibitor, IC50: ARTD10/PARP10 (2.0μM), ARTD1/PARP1 (9.7μM).Formula:C12H13N3O3Colore e forma:SolidPeso molecolare:247.25BAY1238097
CAS:BAY1238097 is a BET inhibitor with anticancer activity and antiproliferative activity for the study of advanced refractory malignancies.Formula:C25H33N5O3Purezza:98.1% - 98.79%Colore e forma:SolidPeso molecolare:451.56Ref: TM-T12660L
1mg51,00€5mg106,00€10mg175,00€25mg375,00€50mg655,00€100mg1.103,00€200mg1.483,00€1mL*10mM (DMSO)119,00€CMP-5 hydrochloride
CAS:CMP-5 hydrochloride: potent, selective PRMT5 inhibitor; inactive against PRMT1/4/7; blocks S2Me-H4R3 on histones.Formula:C21H22ClN3Purezza:98%Colore e forma:SolidPeso molecolare:351.87Dimethyl-bisphenol A
CAS:DMBPA inhibits HIF-1α, promotes its degradation by detaching Hsp90, and reduces Vegfa mRNA expression.Formula:C17H20O2Colore e forma:SolidPeso molecolare:256.34JS1310
CAS:JS1310 is a selective PRMT7 inhibitor (IC50: 5 μM against human PRMT7). JS1310 has shown anti-cancer effects on different cancer cells.Formula:C23H22FN5O3Colore e forma:SolidPeso molecolare:435.45HDAC3-IN-T247
CAS:HDAC3-IN-T247 (HDAC3 inhibitor T247) is a histone deacetylase 3 (HDAC3) inhibitor with antiviral activity that inhibits the proliferation of cancer cells.Formula:C21H19N5OSPurezza:98.11% - 98.94%Colore e forma:SolidPeso molecolare:389.47Ref: TM-T24131
1mg92,00€5mg188,00€10mg311,00€25mg643,00€50mg914,00€100mg1.216,00€1mL*10mM (DMSO)215,00€JAK-IN-14
CAS:JAK-IN-14 (compound 16) is a specific JAK1 inhibitor. It prevents JAK1 phosphorylation by binding to the active site of JAK in immune, inflammation and cancer.Formula:C19H15FN4OPurezza:98.27%Colore e forma:SolidPeso molecolare:334.35Ref: TM-T9764
1mg86,00€5mg180,00€10mg283,00€25mg587,00€50mg938,00€100mg1.491,00€200mg1.985,00€1mL*10mM (DMSO)188,00€Bizine
CAS:Bizine, a Phenelzine analogue, selectively inhibits LSD1 (Ki=59 nM), modulates histone methylation in cancer, and may have neuroprotective uses.Formula:C18H23N3OColore e forma:SolidPeso molecolare:297.39SIRT1-IN-2
CAS:SIRT1-IN-2 (compound 3h) is a potent and selective inhibitor of SIRT1 (silent information regulator 1) with an IC 50 of 1.6 μM [1].Formula:C13H15ClN2OColore e forma:SolidPeso molecolare:250.72(2R/S)-6-PNG
CAS:(2R/S)-6-PNG (6-Prenylnaringenin) from hops is a natural histone deacetylase inhibitor that blocks T-type calcium channels reducing neurogenicity in mice.Formula:C20H20O5Purezza:98%Colore e forma:SolidPeso molecolare:340.37MIV-6
CAS:MIV-6 is an inhibitor of the menin-mixed lineage leukemia interaction.Formula:C27H35N3OColore e forma:SolidPeso molecolare:417.59EPZ032597
CAS:EPZ032597 is a novel selective inhibitor of SMYD2 with an IC50 of 16 nM. EPZ032597 has anticancer activity and prevent and treat pancreatic cancerFormula:C20H23N7OPurezza:99.70%Colore e forma:SolidPeso molecolare:377.44TM6089
CAS:TM6089 is an inhibitor of Prolyl Hydroxylase that stimulates HIF activity without iron chelation, induces angiogenesis, and protects organ against ischemia.Formula:C13H14N4O3SPurezza:99.70%Colore e forma:SolidPeso molecolare:306.34Ref: TM-T17105
1mg52,00€5mg115,00€10mg167,00€25mg301,00€50mg452,00€100mg658,00€200mg884,00€1mL*10mM (DMSO)123,00€JAK-IN-28
CAS:JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of cancer and inflammatory diseases [1].Formula:C20H18ClN7OPurezza:98%Colore e forma:SolidPeso molecolare:407.86JAK-IN-30
CAS:JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with half-maximal inhibitory concentration (IC50Formula:C19H26N8SPurezza:98%Colore e forma:SolidPeso molecolare:398.53Eleven-Nineteen-Leukemia Protein IN-1
CAS:ENL-IN-1: Potent ENL YEATS domain inhibitor with 14.5 nM IC50, enhances thermal stability in vitro.Formula:C27H33N7O2Purezza:98%Colore e forma:SolidPeso molecolare:487.6IDO1 and HDAC1 Inhibitor
CAS:IDO1 and HDAC1 Inhibitor is a dual IDO1 and HDAC1 inhibitor (IC50s: 69.0 nM and 66.5 nM).Formula:C25H22BrFN8O4Purezza:98%Colore e forma:SolidPeso molecolare:597.4HDAC-IN-49
HDAC-IN-49: potent, broad HDAC inhibitor; IC50s: 10-1880 nM for HDAC1-6; strong anti-leukemic, low toxicity to healthy cells.Formula:C26H27FN4O4Colore e forma:SolidPeso molecolare:478.52Angiogenesis agent 1
CAS:Compound C-31, a salidroside-based glycoside, activates HIF-1α and may aid in diabetic limb ischemia studies.Formula:C20H24O7Purezza:98%Colore e forma:SolidPeso molecolare:376.4Sirt1/2-IN-1
CAS:Sirt1/2-IN-1 inhibits SIRT1 (IC50: 1.81 μg/mL) and SIRT2 (2.10 μg/mL), less on SIRT3 (20.5 μg/mL), with anticancer properties.Formula:C22H13ClN2OS2Colore e forma:SolidPeso molecolare:420.93BET bromodomain inhibitor 3
CAS:BET Bromodomain Inhibitor 3 is a BET bromodomain inhibitor with an inhibitory Ki value of >40 µM against BrdT.Formula:C18H17N3O4Purezza:98%Colore e forma:SolidPeso molecolare:339.35PF-07899895
CAS:PF-07899895 (compound 34) is a potent SIK (salt-induced kinase) inhibitor with IC50 values of 1.2/0.9/1.8 nM for SIK1/SIK2/SIK3.Formula:C23H23N5OSPeso molecolare:417.53Ref: TM-T200199
1mg464,00€5mgPrezzo su richiesta10mgPrezzo su richiesta25mg3.372,00€50mgPrezzo su richiestaPIM-1 Inhibitor 2
CAS:PIM-1 Inhibitor 2 (PIM1-IN-2) is a potent Pim-1 inhibitor with potential anti-cancer activity, used in cancer research.Formula:C17H11ClN4OPurezza:98.81%Colore e forma:SolidPeso molecolare:322.75PRMT4-IN-1
CAS:PRMT4-IN-1 is a selective inhibitor of PRMT4, demonstrating an IC50 value of 3.2 nM, and has been shown to reduce the relative viability of MCF7 cells [1].Formula:C23H28FN3OPurezza:98%Colore e forma:SolidPeso molecolare:381.49LP99
CAS:LP99 is an epigenetic probe.Formula:C26H30ClN3O4SPurezza:99.74%Colore e forma:SolidPeso molecolare:516.05Ref: TM-T15784
1mg43,00€5mg96,00€10mg145,00€25mg305,00€50mg442,00€100mgPrezzo su richiesta1mL*10mM (DMSO)97,00€CX-6258
CAS:CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good biological activity and kinase specificity.Formula:C26H24ClN3O3Purezza:97.46%Colore e forma:SolidPeso molecolare:461.94Ref: TM-T1834
1mg37,00€5mg80,00€10mg106,00€25mg208,00€50mg311,00€100mg472,00€200mg658,00€1mL*10mM (DMSO)81,00€DC_C66
CAS:DC_C66 selectively inhibits CARM1 with IC50 of 1.8μM; also affects PRMT1, 6, 5. It's cell-permeable.Formula:C28H22NO2Purezza:98%Colore e forma:SolidPeso molecolare:404.48HDAC-IN-43
CAS:HDAC-IN-43: potent HDAC 1/3/6 inhibitor (IC50: 82 nM HDAC1, 45 nM HDAC3, 24 nM HDAC6); weak PI3K/mTOR (IC50: 3.6μM, 3.7μM); anti-proliferative.Formula:C22H28N6O4Colore e forma:SolidPeso molecolare:440.5BET-IN-2
CAS:BET-IN-2 is a BET inhibitor (IC50: 52 nM for BRD4-BD1).Formula:C23H29N3OPurezza:98%Colore e forma:SolidPeso molecolare:363.5Tripolin A
CAS:<p>Tripolin A is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5 μM and 7 μM, respectively)</p>Formula:C15H11NO3Purezza:98%Colore e forma:SolidPeso molecolare:253.25TNKS-IN-41
CAS:TNKS-IN-41 highly potent and selective inhibitor of tankyrase.Formula:C24H22N10O2Purezza:98%Colore e forma:SolidPeso molecolare:482.5UMB-136
CAS:UMB-136 is a bromodomain BRD4 inhibitor that acts by significantly inducing HIV-1 reactivation.Formula:C24H27N5O2Purezza:98%Colore e forma:SolidPeso molecolare:417.5CM-579
CAS:CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells.Formula:C29H40N4O3Purezza:99.23%Colore e forma:SolidPeso molecolare:492.65Ref: TM-T10840L
1mg55,00€5mg96,00€10mg138,00€25mg217,00€50mg319,00€100mg472,00€1mL*10mM (DMSO)124,00€2′-Deoxy-5-nitrocytidine
CAS:2′-Deoxy-5-nitrocytidine is a DNA Methyltransferase inhibitor that can be used for cancer research[1].Formula:C9H12N4O6Colore e forma:SolidPeso molecolare:272.21SB-284851-BT
CAS:SB-284851-BT: BRD4/p38α/BRDT inhibitor; IC50: BRD4-BD1 1.7µM, BRDT 18µM, BRD4 3.7µM; Kd p38α 0.47nM; reduces IL-8, affects c-Myc/NF-κB.Formula:C26H26FN5OColore e forma:SolidPeso molecolare:443.52PKC-IN-4
CAS:PKC-IN-4 (compound 7l) is a highly potent and orally active inhibitor of atypical protein kinase C (aPKC), exhibiting an IC 50 value of 0.52 μM.Formula:C21H25N5SColore e forma:SolidPeso molecolare:379.52CD161
CAS:CD161: powerful, selective oral BET inhibitor; IC50: 28.2 nM (BRD4 BD1), 7.2 nM (BRD4 BD2); strong anticancer properties.Formula:C26H21N5O2Purezza:98%Colore e forma:SolidPeso molecolare:435.48LSD1-IN-5
CAS:LSD1-IN-5, a reversible LSD1 inhibitor, boosts H3K4me2 without affecting LSD1 expression; IC50: 121 nM.Formula:C15H13BrN2O3Purezza:98%Colore e forma:SolidPeso molecolare:349.18YF479
CAS:YF479 is an inhibitor of histone deacetylase that acts by inhibiting breast tumor growth, metastasis, and recurrence.Formula:C22H27BrN2O5Purezza:98%Colore e forma:SolidPeso molecolare:479.36DC-CPin7
CAS:DC-CPin7, a powerful inhibitor of the bromodomain of CREB-binding protein (CBP), exhibits an IC50 value of 2.5 μM [1].Formula:C19H22N2O5Colore e forma:SolidPeso molecolare:358.39OICR-0547
CAS:OICR-0547 is an inactive derivative of OICR-9429 and is commonly used as a negative control for OICR-9429.Formula:C28H29F3N4O4Purezza:98%Colore e forma:SolidPeso molecolare:542.55HIF-1α inhibitor-1
CAS:HIF-1α inhibitor-1 is a HIF-1 alpha inhibitor.Formula:C15H11N3O4Colore e forma:SolidPeso molecolare:297.27SYK/JAK-IN-1
CAS:SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2.Formula:C24H26N8O3Colore e forma:SolidPeso molecolare:474.52Bisindolylmaleimide II
CAS:protein kinase C (PKC) inhibitorFormula:C27H26N4O2Purezza:98%Colore e forma:SolidPeso molecolare:438.52LSD1-IN-12
CAS:LSD1-IN-12 (compound 2) is an effective inhibitor of LSD1, demonstrating inhibitory Ki values of 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), and 3.5 μM (MAO-BFormula:C16H16N2OColore e forma:SolidPeso molecolare:252.31SRTCX1002
CAS:SRTCX1002 is a SIRT1 Activator Suppressing Inflammatory Responses through Promotion of p65 Deacetylation and NF-κB Activity inhibitor.Formula:C21H19N5O2SPurezza:98%Colore e forma:SolidPeso molecolare:405.47KDM5-C49
CAS:KDM5-C49 is a potent and selective inhibitor of KDM5, which regulates cell proliferation and stem cell self-renewal and differentiation.Formula:C15H24N4O3Purezza:98%Colore e forma:SolidPeso molecolare:308.38SIRT1-IN-3
CAS:SIRT1-IN-3 (compound 3j) is a potent and selective inhibitor of silent information regulator 1 (SIRT1) with an IC 50 of 4.2 μM [1].Formula:C13H15BrN2OColore e forma:SolidPeso molecolare:295.17PU141
CAS:PU141 is a novel inhibitor of histone acetyltransferase (HAT).Formula:C14H9F3N2OSPurezza:98%Colore e forma:SolidPeso molecolare:310.29CHIC35
CAS:CHIC-35 is a selective deacetylase SIRT1 inhibitor.Formula:C14H15ClN2OColore e forma:SolidPeso molecolare:262.73ZYJ-34c
CAS:ZYJ-34c is a potent oral antitumor activities histone deacetylase inhibitor (HDACi).Formula:C31H42N4O7Purezza:98%Colore e forma:SolidPeso molecolare:582.69OTS186935 trihydrochloride
CAS:OTS186935 trihydrochloride is a protein methyltransferase inhibitor of SUV39H2(IC50 of 6.49 nM).Formula:C25H29Cl4N5O2Purezza:98%Colore e forma:SolidPeso molecolare:573.34GSK360A
CAS:GSK360A is a novel prolyl hydroxylase (PHD) domain-containing enzyme inhibitor.Formula:C17H17FN2O5Purezza:98%Colore e forma:SolidPeso molecolare:348.33Valemetostat tosylate
CAS:Valemetostat tosylate is a dual inhibitor of EZH1/2 and used in the research of relapsed/refractory peripheral T-cell lymphoma.Formula:C33H42ClN3O7SPurezza:98%Colore e forma:SolidPeso molecolare:660.22ET-JQ1-OH
CAS:ET-JQ1-OH is an allele-specific BET inhibitor.Formula:C21H21ClN4O2SColore e forma:SolidPeso molecolare:428.93KP-302
CAS:<p>KP-302 is a selective PAD inhibitor, reversing physical disability in multiple sclerosis (MS) mice and clearing T-cell infiltration in the brain.</p>Formula:C20H23N5O2Purezza:99.77%Colore e forma:SolidPeso molecolare:365.43Ref: TM-T88080
1mg60,00€5mg127,00€10mg202,00€25mg416,00€50mg677,00€100mg1.074,00€200mg1.454,00€1mL*10mM (DMSO)140,00€SIRT5 inhibitor 5
CAS:SIRT5 inhibitor 5 is a selective and substrate-competitive SIRT5 inhibitor, which does not occupy the NAD+ binding pocket,cancer and metabolism-related disease.Formula:C21H14ClN3O3SPurezza:99.33%Colore e forma:SolidPeso molecolare:423.87SW155246
CAS:SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).Formula:C16H11ClN2O5SPurezza:98.99%Colore e forma:SolidPeso molecolare:378.79dWIZ-1
CAS:dWIZ-1 ((rac)-dWIZ-1) is a potent WIZ molecular gel degrader tha induction of haemoglobin fetalis (HbF) in erythroblasts, sickle cell disease (SCD).Formula:C22H29N3O4Purezza:92.87% - 92.87%Colore e forma:SolidPeso molecolare:399.48Peficitinib hydrobromide
CAS:Peficitinib hydrobromide is used in the treatment of Psoriasis and Rheumatoid Arthritis.Formula:C18H23BrN4O2Colore e forma:SolidPeso molecolare:407.312MAT2A-IN-5
CAS:MAT2A-IN-5 inhibits MAT2A in tumors, curbing growth in gastric, colon, liver, and pancreatic cancers.Formula:C17H12ClF3N2OColore e forma:SolidPeso molecolare:352.74SIRT6-IN-1
CAS:SIRT6-IN-1, a novel SIRT6 inhibitor, reduces glycemia and improves oral glucose tolerance in unfed wild-type mice.Formula:C19H14N4O5SColore e forma:SolidPeso molecolare:410.4CAY10722
CAS:CAY10722 is a SIRT3 inhibitor, affecting metabolism and cancer cell survival; varying impacts on esophageal and breast cancer.Formula:C21H14Cl2N2O2Colore e forma:SolidPeso molecolare:397.25GS-626510
CAS:GS-626510 is an orally bioavailable inhibitor of BET family bromodomains (Kd: 0.59-3.2 nM for BRD2/3/4; IC50: 83 nM and 78 nM for BD1 and BD2).Formula:C25H22N4OColore e forma:SolidPeso molecolare:394.47LW479
CAS:LW479 is a novel inhibitor of HDAC and is a promising candidate for the prevention of breast cancer.Formula:C21H23BrN2O4SColore e forma:SolidPeso molecolare:479.391,2,3,4,5,6-Hexabromocyclohexane
CAS:Inhibits JAK2 autophosphorylation; non-cytotoxic at 100μM; 1μM reduces activity by 50%, 50μM nearly abolishes it.Formula:C6H6Br6Purezza:98%Colore e forma:SolidPeso molecolare:557.54SPC-180002
CAS:SPC-180002, a dual SIRT1/3 inhibitor, exhibits IC50 values of 1.13 and 5.41 μM for SIRT1 and SIRT3, respectively.Formula:C18H23NO4Purezza:98%Colore e forma:SolidPeso molecolare:317.38KDM5A-IN-1
CAS:KDM5A-IN-1 is a pan-histidine lysine demethylase 5 KDM5 inhibitor that inhibits KDM5A, KDM5B, and KDM5C.Can be used in the study of cancer.Formula:C15H22N4O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:290.36SAR156497
CAS:SAR156497: selective Aurora A/B/C inhibitor; IC50: 0.5 nM (A), 1 nM (B), 3 nM (C); good metabolic stability; anti-tumoral without genetic specificity.Formula:C27H24N4O4Colore e forma:SolidPeso molecolare:468.5Tankyrase-IN-2
CAS:Tankyrase-IN-2 is a selective, potent and orally active inhibitor of tankyrase with IC50s of 10, 7, and 710 nM for TNKS1, TNKS2 as well as PARP1, respectivelyFormula:C17H14F2N2O2Purezza:98%Colore e forma:SolidPeso molecolare:316.36(5H)-Phenanthridinone
CAS:6(5H)-Phenanthridinone suppresses PARP1/2, reduces RDM4 cell growth, downregulates pro-inflammatory genes, and alleviates EAE symptoms in rats.Formula:C13H9NOColore e forma:SolidPeso molecolare:195.22NCC-149
CAS:NCC-149 is a HDAC8 inhibitor.Formula:C16H14N4O2SColore e forma:SolidPeso molecolare:326.37MS-1020
CAS:MS-1020 inhibits JAK3/STAT3, blocks active JAK3, suppresses JAK3/STAT5 signaling, and targets STAT3 in certain cells.Formula:C21H18N2O3Purezza:98%Colore e forma:SolidPeso molecolare:346.38AC-93253 iodide
CAS:AC-93253 iodide is a selective inhibitor of SIRT2. It significantly enhances the acetylation of tubulin p53 and histone H4.Formula:C23H25IN2SPurezza:98%Colore e forma:SolidPeso molecolare:488.43Ac-Lys-AMC
CAS:Ac-Lys-AMC (Hexanamide) is a fluorescent substrate for histone deacetylase HDACs.Formula:C18H23N3O4Purezza:98%Colore e forma:SolidPeso molecolare:345.39ZYJ-34v
CAS:ZYJ-34v is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities.Formula:C27H35N3O6Purezza:98%Colore e forma:SolidPeso molecolare:497.58NSC 698600
CAS:NSC 698600 is a potent inhibitor of PCAF(p300/CBP-associated factor) with IC 50 of 6.51 μM that shows good inhibition activity of cancer cell proliferation [1].Formula:C14H12N2O2SColore e forma:SolidPeso molecolare:272.32Tyk2-IN-5
CAS:Tyk2-IN-5 is a selective and orally active inhibitor of Tyk2 JH2 (Ki: 0.086 nM for Tyk2 JH2; IC50: 25 nM for IFNα).Formula:C21H19FN8O2Purezza:98%Colore e forma:SolidPeso molecolare:434.43JAK3/BTK-IN-2
CAS:<p>JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.</p>Formula:C25H32N8O2Purezza:99.64% - 99.87%Colore e forma:SolidPeso molecolare:476.57Bromodomain IN-1
CAS:Bromodomain IN-1 is an inhibitor of Bromodomain.Formula:C22H23ClN4O3SPurezza:98%Colore e forma:SolidPeso molecolare:458.96BET-BAY 002 (S enantiomer)
CAS:The S-enantiomer of BET-BAY 002, referred to as BET-BAY 002 S enantiomer, is a potent inhibitor of BET (Bromodomain and Extra-Terminal motif proteins).Formula:C22H18ClN5OPurezza:98%Colore e forma:SolidPeso molecolare:403.86TC-E 5001
CAS:dual tankyrase (TNKS) inhibitorFormula:C20H19N5O3SPurezza:98%Colore e forma:SolidPeso molecolare:409.46M133
CAS:M133 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.Formula:C23H24N4OS2Colore e forma:SolidPeso molecolare:436.59GW-841819X
CAS:GW841819X: (+)-JQ1 analogue, BET bromodomain inhibitor, active in vivo against various cancers.Formula:C25H21N5O2Colore e forma:SolidPeso molecolare:423.47OM-137
CAS:OM137 inhibits Aurora kinases, impedes cell growth at high doses, and enhances low-dose paclitaxel effects.Formula:C13H14N4O3SColore e forma:SolidPeso molecolare:306.34ZLD1039
CAS:ZLD1039, an oral EZH2 inhibitor, shows strong PRC2 inhibition at low nanomolar IC50s, and halts breast cancer growth and spread.Formula:C36H48N6O3Purezza:99.5%Colore e forma:SolidPeso molecolare:612.8GNA002
CAS:GNA002 is a highly potent, specific, and covalent EZH2 (Enhancer of zeste homolog 2) inhibitor (IC50: 1.1 μM).Formula:C42H55NO8Purezza:98%Colore e forma:SolidPeso molecolare:701.89ZIKV-IN-2
CAS:ZIKV-IN-2 blocks ZIKV replication, is a strong NS5 MTase inhibitor (IC50: 38.86 μM), and aids Zika virus research.Formula:C39H42O4Colore e forma:SolidPeso molecolare:574.75KU-0058684
CAS:KU-0058684 is a potent PARP and DNA-PK inhibitors.Formula:C19H14FN3O3Colore e forma:SolidPeso molecolare:351.33HOI-07
CAS:HOI-07 is a specific Aurora B inhibitor.Formula:C19H13NO4Colore e forma:SolidPeso molecolare:319.31ML753286
CAS:ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions.Formula:C20H25N3O3Purezza:98%Colore e forma:SolidPeso molecolare:355.43Trotabresib
CAS:Trotabresib (CC-90010) is an orally active inhibitor of BET and can be used in studies about advanced solid tumors.Formula:C21H21NO4SPurezza:99.86%Colore e forma:SolidPeso molecolare:383.46Ref: TM-T36395
1mg92,00€5mg188,00€10mg311,00€25mg528,00€50mg755,00€100mg1.017,00€1mL*10mM (DMSO)215,00€JAK1-IN-4
CAS:JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in NCI-H 1975 cells (IC50 = 227 nM).Formula:C26H32FN9O2Purezza:98%Colore e forma:SolidPeso molecolare:521.59CeMMEC2
CAS:CeMMEC2, a novel inhibitor of BRD4, binds both the first and the second bromodomain of BRD4.Formula:C14H19N5Colore e forma:SolidPeso molecolare:257.33Piribedil Maleate
CAS:Piribedil Maleate is a direct agonist of dopamine that acts by showing selectivity for the D3 subtype.Formula:C20H22N4O6Purezza:98%Colore e forma:SolidPeso molecolare:414.41AC430
CAS:AC430, a specific JAK2 inhibitor for cancer and autoimmune therapy, excels in preclinical trials with low doses. Developed by Ambit.Formula:C19H16FN5OColore e forma:SolidPeso molecolare:349.36Guadecitabine sodium
CAS:Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) .Formula:C18H24N9NaO10PPurezza:98%Colore e forma:SolidPeso molecolare:580.407DC_517
CAS:DC_517 is an inhibitor of DNA methyltransferase 1 (DNMT1) ( IC50: 1.7 μM; Kd: 0.91 μM).Formula:C33H35N3O2Colore e forma:SolidPeso molecolare:505.65L 888607 Racemate
CAS:L 888607 Racemate blocks DP1 and TP receptors with 132 nM and 17 nM affinity.Formula:C19H15ClFNO2SColore e forma:SolidPeso molecolare:375.84BAY-6035-R-isomer
CAS:BAY-6035 is an inhibitor of the methylation of MEKK2 peptide.Formula:C22H28N4O3Colore e forma:SolidPeso molecolare:396.48SC-9
CAS:SC-9 is a protein kinase C activator.Formula:C22H24ClNO2SPurezza:98%Colore e forma:SolidPeso molecolare:401.95TFMB-(S)-2-HG
CAS:TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase.Formula:C13H11F3O4Purezza:98.07%Colore e forma:SolidPeso molecolare:288.22Ref: TM-T24871
2mg35,00€5mg52,00€10mg84,00€25mg155,00€50mg240,00€100mg358,00€500mg753,00€1mL*10mM (DMSO)51,00€Tyk2-IN-7
CAS:Tyk2-IN-7 is an inhibitor of TYK2 JH2, binds to the TYK2 JH2 domain (IC50: 0.00053 μM; Ki.app: 0.00007 μM).Formula:C18H15D3N6O3SPurezza:98%Colore e forma:SolidPeso molecolare:401.46Pulrodemstat Methylbenzenesulfonate
CAS:LSD1-IN-7 Methylbenzenesulfonate is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.Formula:C31H31F2N5O5SPurezza:98%Colore e forma:SolidPeso molecolare:623.67Ilorasertib hydrochloride
CAS:Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s:Formula:C25H22ClFN6O2SPurezza:98.45%Colore e forma:SolidPeso molecolare:525Tetrahydrouridine
CAS:Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.Formula:C9H16N2O6Purezza:98%Colore e forma:SolidPeso molecolare:248.23KDM5B-IN-3
CAS:KDM5B-IN-3 inhibits KDM5B/JARID1B with IC50 of 9.32 μM, useful in gastric cancer studies.Formula:C19H25ClN4O2Colore e forma:SolidPeso molecolare:376.88
