Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2553 prodotti di "Cromatina/Epigenetica"
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BRD-6929
CAS:BRD-6929, a brain-targeted HDAC1/2 inhibitor (IC50 1/8 nM), enhances gnidimacrin's anti-HIV effect, useful in mood behavior studies.Formula:C19H17N3O2SPurezza:98.01% - 99.05%Colore e forma:SolidPeso molecolare:351.42Ref: TM-T10603
5mg48,00€10mg86,00€25mg166,00€50mg289,00€100mg419,00€200mg587,00€1mL*10mM (DMSO)49,00€MC3482
CAS:MC3482 is a specific inhibitor of sirtuin5 (SIRT5).Formula:C33H38N4O8Purezza:98% - 99.90%Colore e forma:SoildPeso molecolare:618.68Ref: TM-T11962
1mg50,00€2mg71,00€5mg105,00€10mg170,00€25mg268,00€50mg423,00€100mg685,00€500mg1.378,00€BMS-986158
CAS:BMS-986158: BET inhibitor, IC50 of 6.6 nM in SCLC, 5 nM in TNBC cells.Formula:C30H33N5O2Purezza:98.78%Colore e forma:SolidPeso molecolare:495.62Ref: TM-T14685
1mg87,00€5mg259,00€10mg465,00€25mg745,00€50mg1.026,00€100mg1.388,00€1mL*10mM (DMSO)283,00€Abexinostat
CAS:Abexinostat (PCI-24781) is a pan-HDAC inhibitor, strongest on HDAC1; less so on HDACs 2, 3, 6, 10. Very select for HDAC8. In Phase 1/2 trials.Formula:C21H23N3O5Purezza:98.19% - 98.43%Colore e forma:SolidPeso molecolare:397.42LIN28 inhibitor LI71
CAS:LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM.Formula:C21H21NO3Purezza:95.88%Colore e forma:SolidPeso molecolare:335.4Ref: TM-T11850
1mg107,00€5mg255,00€10mg414,00€25mg745,00€50mg1.063,00€100mg1.459,00€1mL*10mM (DMSO)341,00€JAK2 Inhibitor V
CAS:JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.Formula:C23H24N2OPurezza:98.36% - 99.15%Colore e forma:SolidPeso molecolare:344.45Ref: TM-T3042
2mg37,00€5mg54,00€10mg80,00€25mg148,00€50mg259,00€100mg477,00€500mg1.063,00€1mL*10mM (DMSO)59,00€ODM-207
CAS:ODM-207 (BET-IN-4) is a potent BRD4 inhibitor.Formula:C22H21N3O3Purezza:99.75%Colore e forma:SolidPeso molecolare:375.42Ref: TM-T10521
1mg44,00€5mg92,00€10mg133,00€25mg235,00€50mg339,00€100mg480,00€200mg660,00€1mL*10mM (DMSO)90,00€YPX-C-05
CAS:YPX-C-05, an isohydroxamic acid derivative, is an HDAC inhibitor with vasodilatory and antihypertensive activity.CAS 번호134608-84-5Formula:C21H19N3O4Purezza:98.09%Colore e forma:SoildPeso molecolare:377.39PKC β pseudosubstrate acetate
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.Purezza:95.42%Colore e forma:SoildIlginatinib
CAS:Ilginatinib (NS-018) is a highly active and orally bioavailable inhibitor of JAK2.Formula:C21H20FN7Purezza:98.4% - 99.01%Colore e forma:SolidPeso molecolare:389.43Ref: TM-T12266
1mg64,00€5mg138,00€10mg187,00€25mg273,00€50mg393,00€100mg562,00€200mg743,00€1mL*10mM (DMSO)133,00€Citric acid trilithium salt tetrahydrate
CAS:Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy ofFormula:C6H13Li3O11Purezza:99.88%Colore e forma:White Crystalline PowderPeso molecolare:281.98PBIT
CAS:PBIT is a JARID1 inhibitor with IC50: 3 μM for JARID1B, 6 μM for JARID1A, and 4.9 μM for JARID1C.Formula:C14H11NOSPurezza:99.61% - 99.83%Colore e forma:SolidPeso molecolare:241.31Ref: TM-T16435
1mg35,00€2mg50,00€5mg75,00€10mg105,00€25mg215,00€50mg340,00€100mg550,00€200mg780,00€1mL*10mM (DMSO)84,00€Uzansertib phosphate
CAS:Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase, inhibiting PIM1, PIM2 and PIM3.Formula:C26H29F3N5O7PPurezza:99.75% - 99.79%Colore e forma:SolidPeso molecolare:611.51Fenbendazole
CAS:Fenbendazole (Fenbendazol) is an antinematodal benzimidazole used in veterinary medicine.Formula:C15H13N3O2SPurezza:99.74%Colore e forma:White To Yellowish PowderPeso molecolare:299.35TRIM24/BRPF1-IN-2
CAS:TRIM24/BRPF1-IN-2 is a TRIM24/BRPF1 dual inhibitor with anticancer activity that inhibits the proliferation of prostate cancer cells.Formula:C20H22N2O4SPurezza:98.69% - 99.13%Colore e forma:SoildPeso molecolare:386.47N-Desmethyltamoxifen hydrochloride
CAS:N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.Formula:C25H28ClNOPurezza:99.15%Colore e forma:SolidPeso molecolare:393.95Bufexamac
CAS:Bufexamac (Bufexamic acid) is a COX inhibitor for IFN-α release with anti-inflammatory, analgesic, and antipyretic action.Formula:C12H17NO3Purezza:99.73%Colore e forma:Acicular CrystalPeso molecolare:223.27Levetiracetam
CAS:Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onsetFormula:C8H14N2O2Purezza:99.67% - 99.86%Colore e forma:White Crystalline PowderPeso molecolare:170.21(R)-CR8
CAS:(R)-CR8 ((R)-Isomer) is a potent and selective CDK inhibitor.
Formula:C24H29N7OPurezza:98.41%Colore e forma:SolidPeso molecolare:431.53SMARCA-BD ligand 1 for Protac
CAS:SMARCA-BD ligand 1 for Protac is a compound capable of binding to SMARCA2, the BAF ATPase subunit, based on the Protac technology for degrading SMARCA2Formula:C14H17N5OPurezza:99.93%Colore e forma:SolidPeso molecolare:271.32MAK683
CAS:MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).Formula:C20H17FN6OPurezza:98.25% - 99.92%Colore e forma:SolidPeso molecolare:376.39Ref: TM-T15201
1mg52,00€5mg107,00€10mg188,00€25mg411,00€50mg607,00€100mg847,00€500mg1.758,00€1mL*10mM (DMSO)95,00€Minocycline hydrochloride
CAS:Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.Formula:C23H28ClN3O7Purezza:99.28% - >99.99%Colore e forma:Bright Yellow-Orange Amorphous Solid Crystalline YellowPeso molecolare:493.94MS402
CAS:MS402 is a novel BD1-selective BET BrD inhibitor.Formula:C20H19ClN2O3Purezza:99.72%Colore e forma:SolidPeso molecolare:370.83Amifostine
CAS:Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.Formula:C5H15N2O3PSPurezza:99.59%Colore e forma:White SolidPeso molecolare:214.22Nicotinamide riboside
CAS:Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-
Formula:C11H15N2O5Purezza:98.82% - 99.58%Colore e forma:SolidPeso molecolare:255.25ZEN-3694
CAS:ZEN-3694 (ZEN 3694) is a bromo-structural domain extra-terminal inhibitor (BETi) with activity in androgen signaling inhibitor (ASI) resistance models and canFormula:C19H19N5OPurezza:98.94% - 99.76%Colore e forma:SolidPeso molecolare:333.39Oltipraz
CAS:Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties.Formula:C8H6N2S3Purezza:98.79% - 99.77%Colore e forma:SolidPeso molecolare:226.34ZL0580
CAS:ZL0580 suppresses HIV by blocking Tat activation, halting transcription, and promoting repressive chromatin at the HIV promoter.Formula:C25H23F3N4O4SPurezza:99.70%Colore e forma:SolidPeso molecolare:532.53Glucosamine hydrochloride
CAS:Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.Formula:C6H13NO5·HClPurezza:99.77%Colore e forma:White Solid CrystallinePeso molecolare:215.63VTP50469
CAS:VTP50469 is a highly selective and orally active small molecule inhibitor of the Menin-MLL protein-protein interaction.Cost-effective and quality-assured.Formula:C32H47FN6O4SPurezza:98.31% - 99.55%Colore e forma:SolidPeso molecolare:630.82Ref: TM-T13336
1mg164,00€5mg334,00€10mg401,00€25mg560,00€50mg715,00€100mg964,00€1mL*10mM (DMSO)465,00€Hydralazine hydrochloride
CAS:Hydralazine hydrochloride, an antihypertensive phthalazine, induces vasodilation and may inhibit tumor DNA methylation.Formula:C8H9ClN4Purezza:99.85% - 99.86%Colore e forma:Yellow Crystals White Crystalline SolidPeso molecolare:196.64GNE-781
CAS:GNE-781: potent CBP inhibitor (IC50: 0.94 nM), also targets BRET/BRD4(1) (IC50: 6.2/5100 nM).Formula:C27H33F2N7O2Purezza:99.25% - 99.64%Colore e forma:SolidPeso molecolare:525.59Ref: TM-T15405
1mg138,00€5mg298,00€10mg485,00€25mg808,00€50mg1.093,00€100mg1.483,00€1mL*10mM (DMSO)343,00€Pulrodemstat benzenesulfonate
CAS:Pulrodemstat benzenesulfonate (CC-90011 benzenesulfonate) is a potent and orally inhibitor of lysine specific demethylase-1 (LSD1) with anticancer effect.Formula:C30H29F2N5O5SPurezza:97.67%Colore e forma:SolidPeso molecolare:609.64Ref: TM-T11882
1mg60,00€2mg86,00€5mg124,00€10mg188,00€25mg329,00€50mg490,00€100mg710,00€1mL*10mM (DMSO)170,00€SNDX-5613
CAS:Revumenib (SNDX-5613) is a potent and selective oral inhibitor of menin-KMT2A interaction.Cost-effective and quality-assured.Formula:C32H47FN6O4SPurezza:99.12% - 99.74%Colore e forma:SolidPeso molecolare:630.82Ref: TM-T12943
1mg73,00€2mg97,00€5mg160,00€10mg274,00€25mg542,00€50mg778,00€100mg1.074,00€1mL*10mM (DMSO)217,00€Indoprofen
CAS:Indoprofen ((±)-Indoprofe) is a non-steroidal anti-inflammatory drug.Formula:C17H15NO3Purezza:99.34%Colore e forma:SolidPeso molecolare:281.31Nefiracetam
CAS:Nefiracetam (DM9384), in Phase 2 trials, enhances GABA, choline, monoamine systems, and treats Ro 5-4864 convulsions.Formula:C14H18N2O2Purezza:97.37%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:246.3Albendazole
CAS:Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.Formula:C12H15N3O2SPurezza:98.21% - 98.76%Colore e forma:Colorless Crystals SolidPeso molecolare:265.33A-395
CAS:A-395 blocks PRC2 (EZH2-EED-SUZ12) interactions, strongly inhibiting the complex with an IC50 of 18 nM.
Formula:C26H35FN4O2SPurezza:98.43%Colore e forma:SolidPeso molecolare:486.65Ilginatinib maleate
CAS:Ilginatinib maleate (NS-018 maleate) is a highly active and orally bioavailable inhibitor of JAK2.
Formula:C25H24FN7O4Purezza:99.74% - 99.82%Colore e forma:SolidPeso molecolare:505.5Delgocitinib
CAS:Delgocitinib is a potent JAK inhibitor (IC50: 2.8-58 nM), treats inflammatory diseases, and is the first topical drug for atopic dermatitis.Formula:C16H18N6OPurezza:99.95%Colore e forma:SolidPeso molecolare:310.35Ref: TM-T15096
1mg169,00€5mg311,00€10mg487,00€25mg929,00€50mg1.415,00€100mg2.062,00€200mg2.775,00€1mL*10mM (DMSO)349,00€Lin28-let-7a antagonist 1
CAS:Lin28-let-7a antagonist 1, with an IC50 of 4.03 μM for Lin28A-let-7a-1 interaction，and shows a clear antagonistic effect against the Lin28-let-7a interaction.Formula:C31H29N5O7Purezza:99.44%Colore e forma:SolidPeso molecolare:583.59Ref: TM-T11851
1mg92,00€5mg216,00€10mg329,00€25mg593,00€50mg893,00€100mg1.311,00€1mL*10mM (DMSO)281,00€5-Azacytidine
CAS:5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.Formula:C8H12N4O5Purezza:98% - 99.79%Colore e forma:Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Peso molecolare:244.2MAT2A inhibitor 2
CAS:MAT2A inhibitor 2 is an inhibitor of methionine adenosyltransferase 2A (MAT2A).Formula:C18H24ClN3O3Purezza:99.52%Colore e forma:SolidPeso molecolare:365.85Phenelzine sulfate
CAS:Phenelzine sulfate is a non-selective and irreversible inhibitor of monoamine oxidase (MAOI), and with antidepressant and anxiolytic.Formula:C8H14N2O4SPurezza:98.38% - 99.83%Colore e forma:SolidPeso molecolare:234.27Golidocitinib
CAS:Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).Formula:C25H31N9O2Purezza:98.87% - 99.88%Colore e forma:SolidPeso molecolare:489.57Centrinone
CAS:Centrinone (LCR-263) (LCR-263) is a reversible inhibitor of polo-like kinase 4 (PLK4; Ki:0.16 nM).Formula:C26H25F2N7O6S2Purezza:98.76%Colore e forma:SolidPeso molecolare:633.65MS417
CAS:MS417 (GTPL7512) is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weakFormula:C20H19ClN4O2SPurezza:99.87%Colore e forma:SolidPeso molecolare:414.91MK8722
CAS:MK8722 is an effective and systemic activator of pan-AMPK.Formula:C24H20ClN3O4Purezza:98.08% - 99.8800%Colore e forma:SolidPeso molecolare:449.89Ref: TM-T16099
1mg37,00€2mg52,00€5mg79,00€10mg119,00€25mg226,00€50mg419,00€100mg617,00€1mL*10mM (DMSO)87,00€L002
CAS:L002 is a potent inhibitor of acetyltransferase p300 with an IC50 of 1.98 μM, blocking histone and p53 acetylation, and may treat cardiac hypertrophy.Formula:C15H15NO5SPurezza:98.59%Colore e forma:SolidPeso molecolare:321.35Decitabine
CAS:Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity.Formula:C8H12N4O4Purezza:98.06% - 99.87%Colore e forma:Physical Description Fine White Crystalline Powder Used As A DrugPeso molecolare:228.21
