Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2553 prodotti di "Cromatina/Epigenetica"
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JAK-IN-29
JAK-IN-29 (Compound 3) is a potent inhibitor of Janus kinases (JAK) [1].Formula:C17H14ClN5O2Purezza:98%Colore e forma:SolidPeso molecolare:355.78KDM2B-IN-2
CAS:KDM2B-IN-2 is a potent histone demethylase (kdm2b) inhibitor.Formula:C21H26N4O2S2Purezza:98.96%Colore e forma:SolidPeso molecolare:430.59Ref: TM-T39389
1mg66,00€5mg144,00€10mg216,00€25mg406,00€50mg607,00€100mg845,00€500mg1.738,00€1mL*10mM (DMSO)159,00€Eicosapentaenoic Acid (Standard)
CAS:Eicosapentaenoic Acid (Standard) is the standard substance of Eicosapentaenoic Acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Eicosapentaenoic Acid is an ω-3 fatty acid and an inhibitor of fatty acid synthase (FASN). Eicosapentaenoic Acid promotes DNA demethylation in the reexpression of the tumor suppressor gene CCAAT/ enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates the RAS/ERK/C/EBPβ pathway in U937 leukemia cells through demethylation of the CpG island of H-RAS intron 1. Eicosapentaenoic Acid promotes the relaxation of vascular smooth muscle cells and vasodilation.Formula:C20H30O2Colore e forma:LiquidPeso molecolare:302.45PCAF-IN-1
CAS:PCAF-IN-1 is a highly selective PCAF inhibitor with potential anti-tumor, anti-inflammatory, and anti-heart disease effects.Formula:C15H11ClN6Colore e forma:SolidPeso molecolare:310.74MC4171
MC4171 is a selective KAT8 inhibitor with antiproliferative activity and can be used to study cancer.Formula:C21H15N3O3Purezza:99.56%Colore e forma:SolidPeso molecolare:357.36DTP3
CAS:DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.Formula:C26H35N7O5Colore e forma:SolidPeso molecolare:525.6TPOP146
CAS:TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4).Formula:C27H35N3O5Purezza:98%Colore e forma:SolidPeso molecolare:481.58Ifidancitinib
CAS:Ifidancitinib (ATI-50002) is a JAK kinase 1/3 inhibitor used to study autoimmune diseases.Formula:C20H18FN5O3Purezza:98.05%Colore e forma:SolidPeso molecolare:395.39KDM4C-IN-1
CAS:KDM4C-IN-1 is aKDM4C inhibitor withial anticancer activity.KDM4C-IN-1 inhibits the growth of HepG2 and A549 cells, and can be used for the study of leukaemia.Formula:C15H14N4O3Purezza:99.33%Colore e forma:SolidPeso molecolare:298.3SGC-iMLLT
CAS:SGC-iMLLT is a potent and selective MLLT1/3-histone interactions inhibitor(IC50 = 0.26 μM),and is a first-in-class chemical probe displaying cellular targetFormula:C22H24N6OPurezza:99.21% - 99.92%Colore e forma:SolidPeso molecolare:388.47(2R)-Octyl-α-hydroxyglutarate
CAS:(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a D-isomer 2-Hydroxyglutarate modified form.Formula:C13H24O5Colore e forma:SolidPeso molecolare:260.33GSK2879552
CAS:GSK2879552: oral, irreversible LSD1 inhibitor with potential cancer-fighting properties.Formula:C23H28N2O2Purezza:99.22%Colore e forma:SolidPeso molecolare:364.48AZ505 ditrifluoroacetate
CAS:AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12 μM).Formula:C33H40Cl2F6N4O8Colore e forma:SolidPeso molecolare:805.59AS-85
CAS:AS-85 is an ASH1L inhibitor with anti-leukemic activity that inhibits leukemic cell growth and increases cLogP.Formula:C26H28F3N5O3S2Purezza:98.96%Colore e forma:SolidPeso molecolare:579.66GSK778
CAS:GSK778 selectively inhibits BD1 bromodomains (BRD2, BRD3, BRD4, BRDT) and impedes cell growth, causing arrest and apoptosis.Formula:C30H33N5O3Purezza:98.42%Colore e forma:SolidPeso molecolare:511.61Ref: TM-T9703
1mg152,00€5mg295,00€10mg477,00€25mg954,00€50mg1.513,00€100mg2.097,00€1mL*10mM (DMSO)44,00€PROTAC EZH2 Degrader-1
CAS:PROTAC EZH2 Degrader-1 suppresses EZH2 methyltransferase activity with IC50 2.7 nM, serving as a potent tool in cancer research and EZH2 inhibition studies.Formula:C54H67N7O8Colore e forma:SolidPeso molecolare:942.15Itacitinib adipate
CAS:Itacitinib adipate: oral JAK1 inhibitor, tested in phase II myelofibrosis trial.Formula:C32H33F4N9O5Colore e forma:SolidPeso molecolare:699.66T-448
CAS:T-448 is a lysine-specific demethylase 1 inhibitor (IC50: 22 nM) that improves learning function in mice.T-448 can be used to study memory deficits.Formula:C19H22N4O3SPurezza:97% - 98.63%Colore e forma:SolidPeso molecolare:386.47Boc-Lys(Ac)-AMC
CAS:Boc-Lys(Ac)-AMC (Boc-L-Lys(Ac)-AMC) is a synthetic substrate coupled to an HDAC-specific fluorophore (Ex/Em = 355 nm/460 nm).Formula:C23H31N3O6Purezza:99.87%Colore e forma:SolidPeso molecolare:445.51Ref: TM-T36578
5mg51,00€10mg77,00€25mg129,00€50mg182,00€100mg268,00€200mg387,00€1mL*10mM (DMSO)52,00€ADTL-SA1215
CAS:ADTL-SA1215 is a SIRT3 activator with SIRT3 deacetylase activity for the study of triple negative breast cancer.Formula:C26H29I2NO3Purezza:99.23%Colore e forma:SolidPeso molecolare:657.32
