Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2575 prodotti di "Cromatina/Epigenetica"
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OTS186935 hydrochloride
OTS186935 HCl inhibits SUV39H2 (IC50 6.49 nM), curbs tumor growth in mice, and modulates γ-H2AX in cancer cells.Formula:C25H27Cl2N5O2Colore e forma:SolidPeso molecolare:522.31TIQ-A
CAS:TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.Formula:C11H7NOSPurezza:99.75%Colore e forma:SolidPeso molecolare:201.24Ref: TM-T50098
1mg52,00€5mg92,00€10mg161,00€25mg290,00€50mg414,00€100mg532,00€200mg737,00€1mL*10mM (DMSO)96,00€Nicotinamide Hydrochloride
CAS:Nicotinamide Hydrochloride, a vitamin B3 form, inhibits SIRT2 and melanoma growth, enhancing NAD+, ATP, ROS, and survival in melanoma mice.Formula:C6H7ClN2OColore e forma:SolidPeso molecolare:158.59Perindopril
CAS:Perindopril, an ACE inhibitor, treats hypertension, heart failure, and coronary artery disease; available as arginine or erbumine.Formula:C19H32N2O5Colore e forma:White PowderPeso molecolare:368.474'-Methoxychalcone
CAS:4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.Formula:C16H14O2Purezza:99.86%Colore e forma:SolidPeso molecolare:238.28HNHA
CAS:HNHA is an inhibitor of HDAC.Formula:C17H21NO2SPurezza:98.04%Colore e forma:SolidPeso molecolare:303.42Ref: TM-T21806
1mg44,00€5mg84,00€10mg135,00€25mg279,00€50mg445,00€100mg640,00€200mg879,00€1mL*10mM (DMSO)90,00€Rucaparib
CAS:Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.Formula:C19H18FN3OPurezza:98.24% - 99.80%Colore e forma:SolidPeso molecolare:323.36Ref: TM-T4463
2mg48,00€5mg73,00€10mg115,00€25mg173,00€50mg235,00€100mg364,00€200mg540,00€500mg869,00€1mL*10mM (DMSO)81,00€TG101209
CAS:TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Formula:C26H35N7O2SPurezza:99% - >99.99%Colore e forma:SolidPeso molecolare:509.67AMPK activator 2
CAS:AMPK activator 2, a chloroformin derivative, may boost cancer treatment by enhancing AMPK and inhibiting mTOR pathways, and cancer cell growth.Formula:C13H18F3N5Purezza:99.86%Colore e forma:SolidPeso molecolare:301.31BMS-P5
CAS:BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor.Formula:C27H33ClN6O2Purezza:99.88%Colore e forma:SolidPeso molecolare:509.04Ref: TM-T22277
2mg44,00€5mg86,00€10mg136,00€25mg268,00€50mg479,00€100mg760,00€200mg1.018,00€1mL*10mM (DMSO)96,00€Selisistat
CAS:Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50=38 nM).Formula:C13H13ClN2OPurezza:98.53% - 99.94%Colore e forma:SolidPeso molecolare:248.71Ref: TM-T6111
5mg48,00€10mg54,00€25mg87,00€50mg133,00€100mg222,00€200mg330,00€500mg535,00€1mL*10mM (DMSO)50,00€Senaparib hydrochloride
CAS:Senaparib hydrochloride is a potent and selective oral PARP1/2 inhibitor with strong antitumor activity.Formula:C24H21ClF2N6O3Colore e forma:SolidPeso molecolare:514.92653-47
CAS:653-47 enhances the effects of 666-15 on inhibiting CREB and is a mild CREB inhibitor itself (IC50: 26.3μM).Formula:C20H19ClN2O3Colore e forma:SolidPeso molecolare:370.83CPI-455
CAS:CPI-455 is a specific KDM5 inhibitor.Formula:C16H14N4OPurezza:97.87% - 99.03%Colore e forma:SolidPeso molecolare:278.31Ref: TM-T3552
1mg34,00€2mg49,00€5mg70,00€10mg105,00€25mg178,00€50mg335,00€100mg505,00€1mL*10mM (DMSO)70,00€GSK591
CAS:GSK591 (GSK3203591), Alternative Names are EPZ015866, GSK3203591, is a potent selective inhibitor of the arginine methyltransferase PRMT5 (IC50=11 nM).Formula:C22H28N4O2Purezza:99.35% - 99.45%Colore e forma:SolidPeso molecolare:380.48Ref: TM-T6853
1mg46,00€2mg58,00€5mg95,00€10mg137,00€25mg268,00€50mg404,00€100mg567,00€1mL*10mM (DMSO)101,00€GSK-J4 Hydrochloride
CAS:GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. It is an ethyl ester derivative of the GSK-J1.Formula:C24H28ClN5O2Purezza:97.95% - 98.23%Colore e forma:SolidPeso molecolare:453.97Ref: TM-T4383
1mg38,00€2mg50,00€5mg84,00€10mg120,00€25mg207,00€50mg344,00€100mg505,00€200mg707,00€1mL*10mM (DMSO)132,00€JW 55
CAS:JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2Formula:C25H26N2O5Purezza:99.31% - 99.76%Colore e forma:SolidPeso molecolare:434.48IDF-11774
CAS:IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).Formula:C23H32N2O2Purezza:98.05%Colore e forma:SolidPeso molecolare:368.51FM-381
CAS:FM381, a JAK3 inhibitor with 127 pM IC50, is 410-3600x more selective over JAK1/2/TYK2.Formula:C24H24N6O2Purezza:98.44%Colore e forma:SolidPeso molecolare:428.49Ref: TM-T5091
1mg47,00€2mg62,00€5mg92,00€10mg128,00€25mg212,00€50mg319,00€100mg485,00€1mL*10mM (DMSO)107,00€SC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formula:C15H8Cl2FN3OPurezza:99.56%Colore e forma:SolidPeso molecolare:336.15Ref: TM-T8719
1mg43,00€5mg87,00€10mg133,00€25mg227,00€50mg344,00€100mg429,00€200mg597,00€1mL*10mM (DMSO)94,00€
