Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2633 prodotti di "Cromatina/Epigenetica"
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EPZ005687
CAS:EPZ005687 is a potent and selective inhibitor of EZH2.Formula:C32H37N5O3Purezza:97.06% - 99.64%Colore e forma:SolidPeso molecolare:539.67C-7280948
CAS:C-7280948 is a PRMT1 inhibitor.Formula:C14H16N2O2SPurezza:99.55% - ≥95%Colore e forma:SolidPeso molecolare:276.35Ref: TM-T2097
5mg46,00€1mL*10mM (DMSO)49,00€10mg66,00€25mg109,00€50mg178,00€100mg268,00€200mg414,00€500mg667,00€DR2313
CAS:DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.Formula:C8H10N2OSPurezza:98.65%Colore e forma:SolidPeso molecolare:182.24JQKD82
CAS:JQKD82 is a selective inhibitor of KDM5 and increases H3K4me3. JQKD82 can be used in studies about the treatment of multiple myeloma.Formula:C27H40N4O5Purezza:100.00%Colore e forma:SolidPeso molecolare:500.63Pacritinib
CAS:Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).Formula:C28H32N4O3Purezza:99.25% - 99.49%Colore e forma:SolidPeso molecolare:472.58CPI203
CAS:CPI203 (CPI 203) is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).Formula:C19H18ClN5OSPurezza:99.13% - 99.77%Colore e forma:SolidPeso molecolare:399.9Apabetalone
CAS:Apabetalone (RVX000222) , an effective BET bromodomain inhibitor, has been investigated for the treatment of diabetes, atherosclerosis, and coronary arteryFormula:C20H22N2O5Purezza:98.08% - ≥98%Colore e forma:SolidPeso molecolare:370.4ZM-447439
CAS:ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.Formula:C29H31N5O4Purezza:99.11% - 99.59%Colore e forma:Pale Yellow SolidPeso molecolare:513.59Bisindolylmaleimide IV
CAS:Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)
Formula:C20H13N3O2Purezza:98.83%Colore e forma:Dark Red SolidPeso molecolare:327.34653-47 hydrochloride
CAS:653-47 hydrochloride boosts CREB inhibition by 666-15 and weakly inhibits CREB itself (IC50: 26.3 μM).Formula:C20H20Cl2N2O3Purezza:99.14%Colore e forma:SolidPeso molecolare:407.29Ref: TM-T8890
1mg87,00€5mg177,00€1mL*10mM (DMSO)203,00€10mg334,00€25mg567,00€50mg807,00€100mg1.099,00€500mg2.205,00€AZ6102
CAS:AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.Formula:C25H28N6OPurezza:97.98% - 99.91%Colore e forma:SolidPeso molecolare:428.53TCS7010
CAS:TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.Formula:C31H31ClFN7O2Purezza:98.49% - 99.62%Colore e forma:SolidPeso molecolare:588.07OAC1
CAS:OAC1 (BAS 00287861) activates Oct4, boosts iPSC efficiency, and speeds up reprogramming.Formula:C14H11N3OPurezza:99.49% - 99.65%Colore e forma:SolidPeso molecolare:237.26Ref: TM-T2040
1mg34,00€2mg47,00€5mg66,00€1mL*10mM (DMSO)66,00€10mg92,00€25mg164,00€50mg299,00€100mg540,00€Amifostine sodium
CAS:Amifostine sodium is a phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.Formula:C5H15N2NaO3PSColore e forma:SolidPeso molecolare:237.21I-CBP112
CAS:I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.Formula:C27H36N2O5Purezza:98.18%Colore e forma:SolidPeso molecolare:468.59Ref: TM-T3969
1mg33,00€2mg50,00€5mg92,00€1mL*10mM (DMSO)92,00€10mg161,00€25mg296,00€50mg425,00€100mg583,00€200mg785,00€Ref: TM-T6S0071
2mg34,00€5mg50,00€1mL*10mM (DMSO)81,00€10mg84,00€25mg152,00€50mg222,00€100mg334,00€200mg494,00€BAZ1A-IN-1
CAS:BAZ1A-IN-1, a potent inhibitor, KD 0.52 μM against BAZ1A, is effective in high-BAZ1A cancer cells, not in low-BAZ1A ones.Formula:C16H12N4O3SPurezza:99.87%Colore e forma:SolidPeso molecolare:340.36Ref: TM-T9552
1mg84,00€5mg177,00€1mL*10mM (DMSO)195,00€10mg268,00€25mg537,00€50mg803,00€100mg1.099,00€200mg1.468,00€I-BRD9
CAS:I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.Formula:C22H22F3N3O3S2Purezza:98.16% - 99.51%Colore e forma:SolidPeso molecolare:497.55Ref: TM-T6859
1mg38,00€2mg49,00€5mg71,00€1mL*10mM (DMSO)79,00€10mg107,00€25mg205,00€50mg389,00€100mg577,00€3-deazaneplanocin A HCl
CAS:3-deazaneplanocin A HCl is both an S-adenosyl-l-homocysteine hydrolase inhibitor and an enhancer of zeste homolog 2(EZH2) inhibitor.Formula:C12H15ClN4O3Purezza:93.24% - 98.9%Colore e forma:SolidPeso molecolare:298.73CPI-455
CAS:CPI-455 is a specific KDM5 inhibitor.Formula:C16H14N4OPurezza:97.87% - 99.03%Colore e forma:SolidPeso molecolare:278.31Ref: TM-T3552
1mg34,00€2mg49,00€5mg70,00€1mL*10mM (DMSO)70,00€10mg105,00€25mg178,00€50mg335,00€100mg505,00€
