Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2633 prodotti di "Cromatina/Epigenetica"
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EDO-S101
CAS:EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.Formula:C19H28Cl2N4O2Purezza:98.02% - 99.44%Colore e forma:SolidPeso molecolare:415.36OAC1
CAS:OAC1 (BAS 00287861) activates Oct4, boosts iPSC efficiency, and speeds up reprogramming.Formula:C14H11N3OPurezza:99.49% - 99.65%Colore e forma:SolidPeso molecolare:237.26Ref: TM-T2040
1mg34,00€2mg47,00€5mg66,00€1mL*10mM (DMSO)66,00€10mg92,00€25mg164,00€50mg299,00€100mg540,00€B2
CAS:B2 (Linazolamide intermediate B impurity 2) promotes inclusion formation in cellular models of Huntington's disease and Parkinson's diseaseFormula:C20H17ClN4O3Purezza:99.66%Colore e forma:SolidPeso molecolare:396.83C-7280948
CAS:C-7280948 is a PRMT1 inhibitor.Formula:C14H16N2O2SPurezza:99.55% - ≥95%Colore e forma:SolidPeso molecolare:276.35Ref: TM-T2097
5mg46,00€1mL*10mM (DMSO)49,00€10mg66,00€25mg109,00€50mg178,00€100mg268,00€200mg414,00€500mg667,00€Niraparib hydrochloride
CAS:Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage and apoptosis.Formula:C19H21ClN4OPurezza:99.26%Colore e forma:SolidPeso molecolare:356.85Ref: TM-T6S0071
2mg34,00€5mg50,00€1mL*10mM (DMSO)81,00€10mg84,00€25mg152,00€50mg222,00€100mg334,00€200mg494,00€Picolinamide
CAS:Picolinamide (Picolinoylamide) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.Formula:C6H6N2OPurezza:99.6%Colore e forma:SolidPeso molecolare:122.12I-BRD9
CAS:I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.Formula:C22H22F3N3O3S2Purezza:98.16% - 99.51%Colore e forma:SolidPeso molecolare:497.55Ref: TM-T6859
1mg38,00€2mg49,00€5mg71,00€1mL*10mM (DMSO)79,00€10mg107,00€25mg205,00€50mg389,00€100mg577,00€Buformin hydrochloride
CAS:Buformin hydrochloride, an oral biguanide antidiabetic, activates AMPK, enhances insulin sensitivity, and inhibits hepatic glucose production.Formula:C6H16ClN5Purezza:97.83%Colore e forma:SolidPeso molecolare:193.68AZD1208
CAS:AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.Formula:C21H21N3O2SPurezza:97.24% - 99.83%Colore e forma:SolidPeso molecolare:379.48Ref: TM-T2300
2mg35,00€5mg49,00€1mL*10mM (DMSO)54,00€10mg71,00€25mg112,00€50mg202,00€100mg358,00€200mg470,00€500mg750,00€MRTX-1719
CAS:MRTX-1719 is a potent and selective inhibitor of the PRMT5/MTA complex with an IC50 value of <10 nM against PRMT5/MTAMTAPDELSDMA cell lines.Cost-effective and quality-assured.Formula:C23H18ClFN6O2Purezza:98.27% - 99.18%Colore e forma:SolidPeso molecolare:464.88Pim1/AKK1-IN-1
CAS:Pim1/AKK1-IN-1: LKB1/AAK1 inhibitor with Kd 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1, also targets MPSK1, TNIK.Formula:C20H13N5OPurezza:97.03% - 98.69%Colore e forma:SolidPeso molecolare:339.35Ref: TM-T5093
1mg85,00€2mg124,00€5mg173,00€1mL*10mM (DMSO)192,00€10mg263,00€25mg464,00€50mg672,00€100mg945,00€SGC-SMARCA-BRDVIII
CAS:SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM,Formula:C19H25N5O3Purezza:99.54% - 99.92%Colore e forma:SolidPeso molecolare:371.43Ref: TM-T9568
1mg44,00€1mL*10mM (DMSO)54,00€5mg66,00€10mg101,00€25mg222,00€50mg356,00€100mg530,00€500mg1.153,00€MI-503
CAS:MI-503 is an efficient and selective Menin-MLL inhibitor. MI-503 has a significant inhibitory effect on human MLL leukemia cell line. Cost-effective and quality-assured.Formula:C28H27F3N8SPurezza:99.87% - 99.99%Colore e forma:SolidPeso molecolare:564.63Ref: TM-TQ0069
1mg50,00€5mg114,00€1mL*10mM (DMSO)141,00€10mg178,00€25mg334,00€50mg557,00€100mg888,00€MS049
CAS:MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC 50 of 34 nM and 43 nM, respectively.Formula:C15H24N2OPurezza:98.91%Colore e forma:SolidPeso molecolare:248.36Ref: TM-T4378
2mg34,00€5mg49,00€1mL*10mM (DMSO)52,00€10mg80,00€25mg149,00€50mg222,00€100mg334,00€200mg494,00€Hispidulin
CAS:Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).Formula:C16H12O6Purezza:98.53% - 99.87%Colore e forma:SolidPeso molecolare:300.26RK-287107
CAS:RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).Formula:C22H26F2N4O2Purezza:99.64%Colore e forma:SolidPeso molecolare:416.46Bobcat339
CAS:Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.Formula:C16H12ClN3OPurezza:97.79% - 98.76%Colore e forma:SolidPeso molecolare:297.74Fucosterol
CAS:Fucosterol, from E. stolonifera, has anti-diabetic, anti-adipogenic, anti-cancer properties; it affects PPARα and C/EBPα to control fat cell formation.Formula:C29H48OPurezza:98% - 99.68%Colore e forma:White PowderPeso molecolare:412.69Nicotinamide riboside chloride
CAS:NR, also SRT647, is a B3 vitamin form; precursor to NAD+.Formula:C11H15ClN2O5Purezza:98.92% - 99.86%Colore e forma:SolidPeso molecolare:290.7
