Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2631 prodotti di "Cromatina/Epigenetica"
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NI-57
CAS:NI-57 inhibits BRPF family proteins: BRPF1 (IC50=3.1nM), BRPF2 (IC50=46nM), BRPF3 (IC50=140nM).Formula:C19H17N3O4SPurezza:99.88% - >99.99%Colore e forma:SolidPeso molecolare:383.42GSK2879552 2HCl (1401966-69-5(free base))
GSK2879552 is an orally available, irreversible inhibitor of lysine specific demethylase 1 (LSD1), with potential antineoplastic activity.
Formula:C23H30Cl2N2O2Purezza:99.87% - ≥95%Colore e forma:SolidPeso molecolare:437.41Ref: TM-T4418
1mg59,00€2mg86,00€5mg109,00€10mg175,00€25mg293,00€50mg411,00€100mg610,00€500mg1.301,00€Ro 31-8220 Mesylate
CAS:Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.Formula:C25H23N5O2S·CH4O3SPurezza:98.79% - 99.02%Colore e forma:SolidPeso molecolare:553.65Ref: TM-T6643
1mg49,00€2mg64,00€5mg92,00€1mL*10mM (DMSO)133,00€10mg150,00€25mg230,00€50mg319,00€100mg475,00€BCI-121
CAS:BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.Formula:C14H18BrN3O2Purezza:99.67%Colore e forma:SolidPeso molecolare:340.22PF-06726304
CAS:PF-06726304: potent EZH2 inhibitor, effective against tumors, Kis at 0.7 nM (wild-type) and 3.0 nM (Y641N mutant).Formula:C22H21Cl2N3O3Purezza:98.19% - 99.51%Colore e forma:SolidPeso molecolare:446.33Ref: TM-T12428L
1mg37,00€2mg52,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg118,00€25mg264,00€50mg477,00€100mg692,00€BRD4770
CAS:BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.Formula:C25H23N3O3Purezza:99.53% - 99.82%Colore e forma:SolidPeso molecolare:413.47Tofacitinib Citrate
CAS:Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).Formula:C22H28N6O8Purezza:99.19% - 99.75%Colore e forma:SolidPeso molecolare:504.49SGC2085 HCl
CAS:SGC2085: potent, selective CARM1 inhibitor; IC50=50 nM; >100x selectivity vs other PRMTs; impacts cancer growth.Formula:C19H24N2O2·HClPurezza:99.91%Colore e forma:SolidPeso molecolare:348.87Ref: TM-T4013
1mg88,00€2mg142,00€5mg180,00€1mL*10mM (DMSO)230,00€10mg324,00€25mg537,00€50mg782,00€100mg1.071,00€WZ4003
CAS:WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively.Formula:C25H29ClN6O3Purezza:99.65% - >99.99%Colore e forma:SolidPeso molecolare:496.99Ref: TM-T6291
5mg48,00€1mL*10mM (DMSO)50,00€10mg73,00€25mg111,00€50mg166,00€100mg241,00€200mg358,00€500mg590,00€ABBV-744
CAS:ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.Formula:C28H30FN3O4Purezza:97.03% - >99.99%Colore e forma:SolidPeso molecolare:491.55Ref: TM-T4697
1mg44,00€2mg56,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg142,00€25mg284,00€50mg409,00€100mg500,00€200mg718,00€DDP-38003 trihydrochloride
DDP-38003 trihydrochloride is a novel, orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor with an IC50 of 84 nM.Formula:C21H29Cl3N4OPurezza:98%Colore e forma:SolidPeso molecolare:459.84Pinometostat
CAS:Pinometostat (EPZ-5676) is a potent DOT1L histone methyltransferase inhibitor. Pinometostat has antitumor activity. Cost effective and quality assured.Formula:C30H42N8O3Purezza:99.19% - 99.86%Colore e forma:SolidPeso molecolare:562.71C646
CAS:C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).Formula:C24H19N3O6Purezza:98% - 99.21%Colore e forma:SolidPeso molecolare:445.42Ref: TM-T2452
2mg46,00€5mg65,00€1mL*10mM (DMSO)65,00€10mg92,00€25mg185,00€50mg360,00€100mg532,00€500mg1.144,00€Brevilin A
CAS:Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formula:C20H26O5Purezza:99.97% - >99.99%Colore e forma:SolidPeso molecolare:346.42Ref: TM-T4672
1mg90,00€5mg203,00€1mL*10mM (DMSO)224,00€10mg350,00€25mg578,00€50mg797,00€100mg1.071,00€500mg2.187,00€BYK204165
CAS:BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)Formula:C15H12N2O2Purezza:99.61%Colore e forma:SolidPeso molecolare:252.27Ref: TM-T7896
1mg44,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg90,00€25mg167,00€50mg236,00€100mg349,00€200mg512,00€COH-SR4
CAS:COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation.Formula:C13H8Cl4N2OPurezza:98.96%Colore e forma:SolidPeso molecolare:350.03MI-463
CAS:MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).Formula:C24H23F3N6SPurezza:99.18% - >99.99%Colore e forma:SolidPeso molecolare:484.54KC7F2
CAS:KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.Formula:C16H16Cl4N2O4S4Purezza:98% - 99.11%Colore e forma:SolidPeso molecolare:570.38Fedratinib
CAS:Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.Formula:C27H36N6O3SPurezza:97.31% - 99.96%Colore e forma:SolidPeso molecolare:524.68Ref: TM-T1995
5mg50,00€1mL*10mM (DMSO)54,00€10mg65,00€50mg107,00€100mg127,00€200mg205,00€500mg447,00€1g592,00€Atractylenolide I
CAS:Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.Formula:C15H18O2Purezza:97.55% - 99.92%Colore e forma:SolidPeso molecolare:230.30
