Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2631 prodotti di "Cromatina/Epigenetica"
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PKC-iota inhibitor 1
CAS:PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Formula:C21H22N6OPurezza:98.82%Colore e forma:SolidPeso molecolare:374.44Ref: TM-T8764
1mg107,00€2mg152,00€5mg219,00€1mL*10mM (DMSO)226,00€10mg349,00€25mg583,00€50mg833,00€100mg1.134,00€500mg2.268,00€ABBV-744
CAS:ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.Formula:C28H30FN3O4Purezza:97.03% - >99.99%Colore e forma:SolidPeso molecolare:491.55Ref: TM-T4697
1mg44,00€2mg56,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg142,00€25mg284,00€50mg409,00€100mg500,00€200mg718,00€BRD4770
CAS:BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.Formula:C25H23N3O3Purezza:99.53% - 99.82%Colore e forma:SolidPeso molecolare:413.47BI 2536
CAS:BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.Formula:C28H39N7O3Purezza:98% - 99.88%Colore e forma:SolidPeso molecolare:521.65Ref: TM-T6173
1mg43,00€2mg56,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg98,00€25mg117,00€50mg187,00€100mg333,00€500mg797,00€KC7F2
CAS:KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.Formula:C16H16Cl4N2O4S4Purezza:98% - 99.11%Colore e forma:SolidPeso molecolare:570.38Bempedoic acid
CAS:Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C.Formula:C19H36O5Purezza:99.85% - 99.94%Colore e forma:SolidPeso molecolare:344.49Ref: TM-T3625
2mg34,00€5mg50,00€1mL*10mM (DMSO)52,00€10mg70,00€25mg118,00€50mg207,00€100mg333,00€500mg797,00€Gandotinib
CAS:LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Formula:C23H25ClFN7OPurezza:99.33% - 99.86%Colore e forma:SolidPeso molecolare:469.94TP-064
CAS:TP-064: Potent, selective PRMT4 inhibitor, IC50 < 10nM for H3 methylation, 100x selectivity, blocks MED12 methylation at 43nM.Formula:C28H34N4O2Purezza:97.85%Colore e forma:SolidPeso molecolare:458.6Ref: TM-T28996
1mg35,00€2mg50,00€5mg74,00€1mL*10mM (DMSO)75,00€10mg113,00€25mg231,00€50mg462,00€100mg673,00€GLPG0634 analog
CAS:GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.Formula:C23H18N6O2Purezza:99.52% - >99.99%Colore e forma:SolidPeso molecolare:410.43Ref: TM-T3076
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg137,00€25mg250,00€50mg442,00€100mg623,00€500mg1.305,00€JMJD7-IN-1
CAS:JMJD7-IN-1 (Benzoic acid, 2,4-dichloro-, 5-nitro-8-quinolinyl ester) is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM.Formula:C16H8Cl2N2O4Purezza:99.66%Colore e forma:SolidPeso molecolare:363.15PF-9366
CAS:PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).Formula:C20H19ClN4Purezza:97.28% - 99.88%Colore e forma:SolidPeso molecolare:350.84Ref: TM-T5191
1mg46,00€1mL*10mM (DMSO)92,00€5mg96,00€10mg130,00€25mg227,00€50mg321,00€100mg442,00€200mg642,00€Atractylenolide I
CAS:Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.Formula:C15H18O2Purezza:97.55% - 99.92%Colore e forma:SolidPeso molecolare:230.30MI-463
CAS:MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).Formula:C24H23F3N6SPurezza:99.18% - >99.99%Colore e forma:SolidPeso molecolare:484.54GSK2879552 2HCl (1401966-69-5(free base))
GSK2879552 is an orally available, irreversible inhibitor of lysine specific demethylase 1 (LSD1), with potential antineoplastic activity.
Formula:C23H30Cl2N2O2Purezza:99.87% - ≥95%Colore e forma:SolidPeso molecolare:437.41Ref: TM-T4418
1mg59,00€2mg86,00€5mg109,00€10mg175,00€25mg293,00€50mg411,00€100mg610,00€500mg1.301,00€PFI-1
CAS:PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.Formula:C16H17N3O4SPurezza:98.74% - 99.19%Colore e forma:SolidPeso molecolare:347.39PLX51107
CAS:PLX51107 is a potent and selective BET inhibitor (Kds: 1.6, 2.1, 1.7, and 5 nM for BRD2-BD1, BRD3-BD1, BRD4-BD1, and BRDT-BD1).Formula:C26H22N4O3Purezza:99.75%Colore e forma:SolidPeso molecolare:438.48Ref: TM-TQ0253
1mg52,00€2mg77,00€5mg113,00€1mL*10mM (DMSO)124,00€10mg178,00€25mg313,00€50mg464,00€100mg672,00€Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formula:C25H21FN6O2SPurezza:96.17% - 97.49%Colore e forma:SolidPeso molecolare:488.54BRD9539
CAS:BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 μMFormula:C24H21N3O3Purezza:98% - 99.57%Colore e forma:SolidPeso molecolare:399.44Succinic acid sodium
CAS:Succinic acid sodium is an orally active anxiolytic.Formula:C4H6O4·xNaColore e forma:SolidWM-8014
CAS:WM-8014 (MOZ-IN-3) is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases.Formula:C20H17FN2O3SPurezza:99.64%Colore e forma:SolidPeso molecolare:384.42Ref: TM-T4362
1mg54,00€2mg78,00€5mg109,00€1mL*10mM (DMSO)129,00€10mg166,00€25mg316,00€50mg470,00€100mg682,00€
