Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2623 prodotti di "Cromatina/Epigenetica"
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[Ala107]-MBP (104-118) acetate
[Ala107]-MBP (104-118) acetate ([Ala107]-MBP ) is synthetic peptide analog of bovine myelin basic protein (MBP).Formula:C59H108N20O21Purezza:99.23%Colore e forma:SolidPeso molecolare:1553.72Resminostat hydrochloride
CAS:Resminostat hydrochloride (RAS2410 hydrochloride) is an effective inhibitor of HDAC1/HDAC3/HDAC6 (IC50: 42.5/50.1/71.8 nM), respectively, and shows less potentFormula:C16H20ClN3O4SPurezza:97.63% - 99.68%Colore e forma:SolidPeso molecolare:385.86KA2507
CAS:KA2507 is a potent and selective HDAC6 inibitor with an IC50 of 2.5nM.Formula:C16H14N6O2Purezza:99.03%Colore e forma:SolidPeso molecolare:322.32Ref: TM-T9148
1mL*10mM (DMSO)33,00€1mg39,00€5mg84,00€10mg120,00€25mg222,00€50mg334,00€100mg447,00€200mg623,00€Go 6983
CAS:Go 6983 is a PKC inhibitor with IC50 values of 7, 7, 6, 10, and 60 nM for PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, respectively. High-Quality, Low-Cost!Formula:C26H26N4O3Purezza:98.41% - 99.85%Colore e forma:SolidPeso molecolare:442.51Ref: TM-T6313
1mg40,00€2mg52,00€5mg79,00€1mL*10mM (DMSO)84,00€10mg119,00€25mg233,00€50mg368,00€100mg533,00€Sotrastaurin
CAS:Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).Formula:C25H22N6O2Purezza:98% - 99.70%Colore e forma:SolidPeso molecolare:438.48Ref: TM-T6278
1mg44,00€5mg86,00€1mL*10mM (DMSO)94,00€10mg135,00€25mg254,00€50mg423,00€100mg605,00€200mg845,00€AK-7
CAS:AK-7 is a brain-permeable SIRT2 inhibitor and to characterize its cholesterol-reducing properties in neuronal models with an IC50 of 15.5 μM.Formula:C19H21BrN2O3SPurezza:98.43% - 99.34%Colore e forma:SolidPeso molecolare:437.35Ref: TM-T5490
1mg34,00€2mg47,00€5mg71,00€1mL*10mM (DMSO)89,00€10mg100,00€25mg177,00€50mg313,00€100mg512,00€PKC ζ pseudosubstrate acetate
PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide.Formula:C78H132N30O18Purezza:98.78%Colore e forma:SolidPeso molecolare:1778.10Picolinamide
CAS:Picolinamide (Picolinoylamide) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.Formula:C6H6N2OPurezza:99.6%Colore e forma:SolidPeso molecolare:122.12MS049
CAS:MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC 50 of 34 nM and 43 nM, respectively.Formula:C15H24N2OPurezza:98.91%Colore e forma:SolidPeso molecolare:248.36Ref: TM-T4378
2mg34,00€5mg49,00€1mL*10mM (DMSO)52,00€10mg80,00€25mg149,00€50mg222,00€100mg334,00€200mg494,00€TCS-PIM-1-4a
CAS:SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).Formula:C11H6F3NO2SPurezza:99.89%Colore e forma:SolidPeso molecolare:273.23PTACH
CAS:PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).Formula:C20H26N2O2S2Purezza:87.44% - 99.74%Colore e forma:SolidPeso molecolare:390.56MS023
CAS:MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8,Formula:C17H25N3OPurezza:98.31% - 99.87%Colore e forma:SolidPeso molecolare:287.4Ref: TM-T6900
1mg37,00€2mg49,00€1mL*10mM (DMSO)79,00€5mg84,00€10mg113,00€25mg230,00€50mg358,00€100mg532,00€500mg1.153,00€E1231
CAS:E1231 is an activator of SIRT1 . E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression.Formula:C21H21N3O3Purezza:98.45%Colore e forma:SolidPeso molecolare:363.41Ref: TM-T9106
1mg34,00€5mg70,00€1mL*10mM (DMSO)94,00€10mg99,00€25mg195,00€50mg311,00€100mg449,00€500mg888,00€R59949
CAS:R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.Formula:C28H25F2N3OSPurezza:97.04%Colore e forma:SolidPeso molecolare:489.58Ref: TM-T26019
1mg39,00€2mg52,00€5mg87,00€1mL*10mM (DMSO)95,00€10mg138,00€25mg281,00€50mg425,00€100mg625,00€200mg883,00€EDO-S101
CAS:EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.Formula:C19H28Cl2N4O2Purezza:98.02% - 99.44%Colore e forma:SolidPeso molecolare:415.36ACY-738
CAS:ACY-738 demonstrates inhibitory activity against recombinant HDAC6 (IC50: 1.7 nM), with respective average selectivity over class I HDACs being 100-fold.Formula:C14H14N4O2Purezza:98.85% - 99.89%Colore e forma:SolidPeso molecolare:270.29Ref: TM-T3509
1mg46,00€2mg62,00€5mg90,00€1mL*10mM (DMSO)100,00€10mg165,00€25mg268,00€50mg439,00€100mg582,00€CAY10602
CAS:CAY10602 activates SIRT1, suppresses NF-κB/TNF-α in THP-1 cells with 75% efficacy at 60 μM, non-toxic.Formula:C22H15FN4O2SPurezza:98.92%Colore e forma:SolidPeso molecolare:418.44SKLB-23bb
CAS:SKLB-23bb is an orally bioavailable HDAC6-selective inhibitor and also has microtubule-disrupting ability.Formula:C21H24N4O4Purezza:97.58%Colore e forma:SolidPeso molecolare:396.44Ref: TM-T5830
1mg50,00€5mg133,00€1mL*10mM (DMSO)147,00€10mg187,00€25mg304,00€50mg424,00€100mg587,00€200mg800,00€GSK121
CAS:GSK121 is an inhibitor of selective PAD4.
Formula:C25H26F3N5O3Purezza:98.92%Colore e forma:SolidPeso molecolare:501.51PJ34
CAS:PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.
Formula:C17H17N3O2Purezza:95.05% - 99.85%Colore e forma:SolidPeso molecolare:295.34
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