Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2622 prodotti di "Cromatina/Epigenetica"
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TH34
CAS:TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.Formula:C15H16N2O2Purezza:98.32%Colore e forma:SolidPeso molecolare:256.3HIF-2α-IN-4
CAS:HIF-2a translation inhibitor is a compound used as a molecular building block.Formula:C9H9N3O4S2Purezza:≥98%Colore e forma:SolidPeso molecolare:287.32Ref: TM-T50099
5mg37,00€1mL*10mM (DMSO)44,00€10mg60,00€25mg111,00€50mg200,00€100mg299,00€200mg430,00€SP-146
SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).Formula:C25H20FN7OPurezza:97.82%Colore e forma:SolidPeso molecolare:453.47Ref: TM-T8685
1mg84,00€5mg166,00€1mL*10mM (DMSO)168,00€10mg245,00€25mg404,00€50mg567,00€100mg767,00€200mg1.018,00€SirReal2
CAS:SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.Formula:C22H20N4OS2Purezza:99.52% - 99.75%Colore e forma:SolidPeso molecolare:420.55Ref: TM-T6984
1mg37,00€2mg52,00€5mg74,00€1mL*10mM (DMSO)86,00€10mg102,00€25mg187,00€50mg295,00€100mg477,00€Selisistat R-enantiomer
CAS:Selisistat R-enantiomer (EX-527 (R-enantiomer)) is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 μM).Formula:C13H13ClN2OPurezza:99.8%Colore e forma:SolidPeso molecolare:248.71Ref: TM-T15263
1mg101,00€2mg150,00€5mg245,00€1mL*10mM (DMSO)269,00€10mg356,00€25mg597,00€50mg835,00€100mg1.108,00€Selisistat S-enantiomer
CAS:Selisistat S-enantiomer (EX-527 S-enantiomer) is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT2/3.Formula:C13H13ClN2OPurezza:99.86%Colore e forma:SolidPeso molecolare:248.71Ref: TM-T7058
1mg142,00€2mg203,00€5mg314,00€1mL*10mM (DMSO)359,00€10mg447,00€25mg713,00€50mg1.018,00€TPPB
CAS:TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).Formula:C27H30F3N3O3Purezza:97.71% - 98.00%Colore e forma:SolidPeso molecolare:501.54Piribedil
CAS:Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.Formula:C16H18N4O2Purezza:99.79% - 99.82%Colore e forma:SolidPeso molecolare:298.34Pep2m, myristoylated acetate
Pep2m, a myristoylated acetate, inhibits GluA2-NSF interaction, reducing AMPA receptor function and expression in neurons.Formula:C65H122N18O16SPurezza:99.62%Colore e forma:SolidPeso molecolare:1443.96dBET1
CAS:dBET1 fuses (+)-JQ1 with thalidomide, degrades BET proteins via cereblon (EC50: 430 nM), and triggers apoptosis.Formula:C38H37ClN8O7SPurezza:98.02% - 99.3%Colore e forma:SolidPeso molecolare:785.27Ref: TM-T4495
1mg50,00€5mg99,00€1mL*10mM (DMSO)145,00€10mg161,00€25mg268,00€50mg427,00€100mg650,00€200mg888,00€HDAC-IN-3
CAS:HDAC-IN-3 (GSK3117391A) is a potent histone deacetylase (HDAC) inhibitor, and treatment chronic inflammatory disorders.Formula:C22H33N3O4Purezza:98.61%Colore e forma:SolidPeso molecolare:403.52ZM39923 hydrochloride
CAS:ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Formula:C23H25NO·HClPurezza:98.05%Colore e forma:SolidPeso molecolare:367.91Valrubicin
CAS:Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.Formula:C34H36F3NO13Purezza:98.63%Colore e forma:SolidPeso molecolare:723.64MK-8745
CAS:MK-8745 is a potent and selective Aurora A inhibitor.Formula:C20H19ClFN5OSPurezza:99.09% - 99.79%Colore e forma:SolidPeso molecolare:431.91JANEX-1
CAS:JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.Formula:C16H15N3O3Purezza:98% - 99.81%Colore e forma:SolidPeso molecolare:297.31SGC2085
CAS:SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).Formula:C19H24N2O2Purezza:99.61% - 99.71%Colore e forma:SolidPeso molecolare:312.41Ref: TM-T7089
1mg84,00€2mg113,00€1mL*10mM (DMSO)152,00€5mg215,00€10mg324,00€25mg533,00€50mg777,00€100mg1.071,00€CPI-1205
CAS:CPI-1205 是一种高效的选择性 EZH2 抑制剂（IC50：0.002 μM，EC50：0.032 μM）。Formula:C27H33F3N4O3Purezza:98.71% - 99.7%Colore e forma:SolidPeso molecolare:518.57TMP269
CAS:TMP269: Class IIa HDAC inhibitor; HDAC4 IC50=157 nM, HDAC5 IC50=97 nM, HDAC7 IC50=43 nM, HDAC9 IC50=23 nM.Formula:C25H21F3N4O3SPurezza:98% - 99.72%Colore e forma:SolidPeso molecolare:514.52Ref: TM-T1857
2mg69,00€5mg90,00€1mL*10mM (DMSO)115,00€10mg153,00€25mg246,00€50mg444,00€100mg537,00€200mg773,00€500mg1.161,00€ZIP acetate(863987-12-6 free base)
ZIP acetate inhibits PKMζ (protein kinase Mζ), affecting LTP maintenance and spatial memory, with an IC50 of 1-2.5 μM.Formula:C92H158N30O19Purezza:94.68%Colore e forma:SolidPeso molecolare:1988.43SC-514
CAS:SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.Formula:C9H8N2OS2Purezza:99.88% - >99.99%Colore e forma:SolidPeso molecolare:224.3
