Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2615 prodotti di "Cromatina/Epigenetica"
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(Z)-LFM-A13
CAS:(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.Formula:C11H8Br2N2O2Purezza:99.88%Colore e forma:SolidPeso molecolare:360Niraparib
CAS:Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.Formula:C19H20N4OPurezza:98% - 99.91%Colore e forma:SolidPeso molecolare:320.39Ref: TM-T3231
5mg57,00€1mL*10mM (DMSO)63,00€10mg84,00€25mg105,00€50mg137,00€100mg205,00€200mg304,00€500mg515,00€AKBA
CAS:AKBA (3-O-Acetyl-11-keto-beta-boswellic acid), a natural component from frankincense, is a novel activator of Nrf2.Formula:C32H48O5Purezza:97.85% - 99.77%Colore e forma:SolidPeso molecolare:512.72MN-64
CAS:MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.Formula:C18H16O2Purezza:99.5% - 99.93%Colore e forma:SolidPeso molecolare:264.32SGC0946
CAS:SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.Formula:C28H40BrN7O4Purezza:98% - 99.82%Colore e forma:SolidPeso molecolare:618.57SMI-16a
CAS:SMI-16a (PIM1/2 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (Formula:C13H13NO3SPurezza:99.99%Colore e forma:SolidPeso molecolare:263.31Ref: TM-T3989
1mg34,00€2mg46,00€5mg66,00€1mL*10mM (DMSO)87,00€10mg93,00€25mg152,00€50mg222,00€100mg334,00€OF-1
CAS:OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain.Formula:C17H18BrN3O4SPurezza:98.55% - ≥95%Colore e forma:SolidPeso molecolare:440.31Ref: TM-T2127
1mg35,00€5mg74,00€1mL*10mM (DMSO)74,00€10mg123,00€25mg240,00€50mg385,00€100mg595,00€200mg833,00€AT9283
CAS:AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).Formula:C19H23N7O2Purezza:99.83% - 99.98%Colore e forma:SolidPeso molecolare:381.43Ref: TM-T3068
2mg39,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg111,00€25mg231,00€50mg371,00€100mg595,00€200mg833,00€SETDB1-TTD-IN-1
CAS:SETDB1-TTD-IN-1 is a potent and selective inhibitor of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD, Kd = 88 nM).Cost-effective and quality-assured.Formula:C28H31N5O2Purezza:98.26% - 99.96%Colore e forma:SolidPeso molecolare:469.58JMJD7-IN-1
CAS:JMJD7-IN-1 (Benzoic acid, 2,4-dichloro-, 5-nitro-8-quinolinyl ester) is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM.Formula:C16H8Cl2N2O4Purezza:99.66%Colore e forma:SolidPeso molecolare:363.15PF-9366
CAS:PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).Formula:C20H19ClN4Purezza:97.28% - 99.88%Colore e forma:SolidPeso molecolare:350.84Ref: TM-T5191
1mg46,00€1mL*10mM (DMSO)92,00€5mg96,00€10mg130,00€25mg227,00€50mg321,00€100mg442,00€200mg642,00€AG-270
CAS:AG-270 is an allosteric and orally active inhibitor of MAT2A.Formula:C30H27N5O2Purezza:98.28% - 98.87%Colore e forma:SolidPeso molecolare:489.57Ref: TM-T9050
2mgPrezzo su richiesta1mg110,00€5mg256,00€10mg378,00€25mg628,00€50mg882,00€100mg1.225,00€200mg1.673,00€C-82
CAS:C-82 is a specific CBP/β-catenin antagonist. It inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300.Formula:C33H34N6O4Purezza:98.86% - 99.66%Colore e forma:SolidPeso molecolare:578.66Itacitinib
CAS:Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.Formula:C26H23F4N9OPurezza:96.4% - 99.5%Colore e forma:SolidPeso molecolare:553.51A-966492
CAS:A-96649 is a new-type and effective inhibitor. The Ki of A-966492 for PARP1 and PARP2 is 1 nM and 1.5 nM, respectively.Formula:C18H17FN4OPurezza:98.53% - 99.27%Colore e forma:SolidPeso molecolare:324.35Ref: TM-T6366
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg94,00€25mg163,00€50mg261,00€100mg374,00€200mg530,00€GSK503
CAS:GSK-503, a potent EZH2 inhibitor, has potential antitumor activity.Formula:C31H38N6O2Purezza:98% - 99.89%Colore e forma:SolidPeso molecolare:526.67PFI-4
CAS:PFI-4 is a potent and selective and cell-permeable BRPF1 bromodomain inhibitor.Formula:C21H24N4O3Purezza:99.53% - ≥95%Colore e forma:SolidPeso molecolare:380.44NI-57
CAS:NI-57 inhibits BRPF family proteins: BRPF1 (IC50=3.1nM), BRPF2 (IC50=46nM), BRPF3 (IC50=140nM).Formula:C19H17N3O4SPurezza:99.88% - >99.99%Colore e forma:SolidPeso molecolare:383.42Menin-MLL inhibitor MI-2
CAS:Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.Formula:C18H25N5S2Purezza:97.46%Colore e forma:SolidPeso molecolare:375.55Ref: TM-T2649
2mg39,00€5mg58,00€1mL*10mM (DMSO)64,00€10mg84,00€25mg160,00€50mg230,00€100mg356,00€200mg522,00€Molibresib besylate
CAS:Molibresib besylate (GSK 525762C) is a BET protein family inhibitor used in the study of refractory hematologic malignant diseases.Formula:C28H28ClN5O5SPurezza:99.64% - 99.64%Colore e forma:SolidPeso molecolare:582.07
