Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2615 prodotti di "Cromatina/Epigenetica"
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TP-3654
CAS:TP-3654 is a second-generation Pim kinase inhibitor (Ki values against Pim-1/3: 5/42 nM).Formula:C22H25F3N4OPurezza:99.8% - 99.95%Colore e forma:SolidPeso molecolare:418.46E7449
CAS:E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.Formula:C18H15N5OPurezza:97.13%Colore e forma:SolidPeso molecolare:317.34Ref: TM-T4471
1mg34,00€5mg88,00€1mL*10mM (DMSO)88,00€10mg114,00€25mg178,00€50mg269,00€100mg399,00€200mg590,00€Protosappanin A
CAS:Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.Formula:C15H12O5Purezza:99.42% - 99.82%Colore e forma:SolidPeso molecolare:272.25Ref: TM-TJS1779
1mg88,00€1mL*10mM (DMSO)178,00€5mg195,00€10mg318,00€25mg523,00€50mg743,00€100mg999,00€Molibresib
CAS:Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).Formula:C22H22ClN5O2Purezza:97.70% - 99.08%Colore e forma:SolidPeso molecolare:423.9Ref: TM-T1906
1mg40,00€2mg54,00€1mL*10mM (DMSO)87,00€5mg88,00€10mg118,00€25mg205,00€50mg339,00€100mg507,00€200mg712,00€500mg1.108,00€(+)-JQ1 PA
CAS:(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM).Formula:C22H20ClN5OSPurezza:98.36%Colore e forma:SolidPeso molecolare:437.95WM-1119
CAS:WM-1119 is a highly potent, selective KAT6A/B inhibitorFormula:C18H13F2N3O3SPurezza:96.59% - 99.58%Colore e forma:SolidPeso molecolare:389.38XD14
CAS:XD14 inhibits BET bromodomains with Kd: BRD4(1) 160nM, BRD2(1) 170nM, BRD3(1) 380nM, BRD3(2) 490nM, BRD2(2) 830nM, BRD4(2) 850nM.
Formula:C20H27N3O5SPurezza:97.46%Colore e forma:SolidPeso molecolare:421.51FL-411
CAS:FL-411 (BRD4-IN-1) is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for BRD4.Formula:C18H19N3O2SPurezza:98.19%Colore e forma:SolidPeso molecolare:341.43GSK3685032
CAS:GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).
Formula:C22H24N6OSPurezza:98.56% - 99.49%Colore e forma:SolidPeso molecolare:420.53Daminozide
CAS:Daminozide (Succinic Acid) is a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily.Formula:C6H12N2O3Purezza:99.86%Colore e forma:White Crystalline Solid Physical Description Odorless White Crystals Or Powder (Ntp 1992)Peso molecolare:160.17GSK-5959
CAS:GSK-5959 is a selective BRPF1 inhibitor with IC50 ~80 nM, 100-fold more specific than 35 other bromodomains.Formula:C22H26N4O3Purezza:98.35% - 98.65%Colore e forma:SolidPeso molecolare:394.47Deucravacitinib
CAS:Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.Formula:C20H19D3N8O3Purezza:98.52% - >99.99%Colore e forma:SolidPeso molecolare:425.46Ref: TM-T14687
1mg56,00€5mg137,00€1mL*10mM (DMSO)149,00€10mg248,00€25mg389,00€50mg575,00€100mg817,00€Momelotinib
CAS:Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.Formula:C23H22N6O2Purezza:97.07% - 99.56%Colore e forma:SolidPeso molecolare:414.46Ref: TM-T1849
1mg35,00€2mg50,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg89,00€25mg158,00€50mg245,00€100mg385,00€200mg592,00€MS436
CAS:MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.Formula:C18H17N5O3SPurezza:97.95% - 98.92%Colore e forma:SolidPeso molecolare:383.42Ref: TM-T1854
2mg42,00€5mg62,00€1mL*10mM (DMSO)69,00€10mg95,00€25mg172,00€50mg268,00€100mg429,00€200mg615,00€SNS-314 Mesylate
CAS:SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.Formula:C18H15ClN6OS2·CH4O3SPurezza:99.44% - 99.92%Colore e forma:SolidPeso molecolare:527.04BAY-598
CAS:BAY 598 is a potent and selective competitive inhibitor of SMYD2, exhibiting >100-fold selectivity over SMYD3, SUV420H1, and SUV420H2. Cost-effective and quality-assured.Formula:C22H20Cl2F2N6O3Purezza:99.18% - 99.78%Colore e forma:SolidPeso molecolare:525.342',3',5'-triacetyl-5-Azacytidine
CAS:2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.Formula:C14H18N4O8Purezza:98.34%Colore e forma:SolidPeso molecolare:370.31Ref: TM-T7840
2mg38,00€5mg50,00€1mL*10mM (DMSO)60,00€10mg75,00€25mg122,00€50mg177,00€100mg266,00€200mg385,00€GSK046
CAS:GSK046 (iBET-BD2), potent oral BET BD2 inhibitor; IC50: BRD2 (264 nM), BRD3 (98 nM), BRD4 (49 nM), BRDT (214 nM); immunomodulatory.Formula:C23H27FN2O4Purezza:99.97%Colore e forma:SolidPeso molecolare:414.47Ref: TM-T8932
1mg57,00€5mg120,00€1mL*10mM (DMSO)133,00€10mg200,00€25mg447,00€50mg715,00€100mg1.108,00€200mg1.485,00€RO495
CAS:RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assaysFormula:C17H14Cl2N6OPurezza:97.94%Colore e forma:SolidPeso molecolare:389.24Ref: TM-T22416
1mg46,00€5mg86,00€1mL*10mM (DMSO)94,00€10mg126,00€25mg235,00€50mg344,00€100mg465,00€200mg625,00€GSK6853
CAS:GSK6853 is a potent, soluble, cell-active, and highly selective inhibitor of the BRPF1 bromodomain.Formula:C22H27N5O3Purezza:98.71% - 99.21%Colore e forma:SolidPeso molecolare:409.48
