Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2612 prodotti di "Cromatina/Epigenetica"
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MIV-6R
CAS:MIV-6R inhibits Menin-MLL interaction (IC50: 56 nM) and can be used to study leukemia.Formula:C27H35N3OPurezza:99.81% - 99.88%Colore e forma:SolidPeso molecolare:417.59RGFP966 (E-isomer)
CAS:RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM, exhibits > 200-fold selectivity over other HDAC.Formula:C21H19FN4OPurezza:99.93%Colore e forma:SolidPeso molecolare:362.4MS023 dihydrochloride
CAS:MS023 dihydrochloride (MS023 2HCl) is a human type I protein arginine methyltransferase inhibitor with antitumour activity for the study of breast cancer.Formula:C17H27Cl2N3OPurezza:99.52%Colore e forma:SolidPeso molecolare:360.32Cerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Formula:C20H28ClN7O3SPurezza:99.85%Colore e forma:SolidPeso molecolare:482R 59-022
CAS:R 59-022 (DKGI-I) is a DGK inhibitor and a 5-HT Receptor antagonist that blocks filovirus internalization in host cells.Formula:C27H26FN3OSPurezza:98.55%Colore e forma:SolidPeso molecolare:459.58Ref: TM-T16709
1mg35,00€5mg74,00€10mg119,00€25mg269,00€50mg447,00€100mg733,00€200mg973,00€1mL*10mM (DMSO)75,00€PFI-2
CAS:PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over otherFormula:C23H25F4N3O3SPurezza:99.38%Colore e forma:SolidPeso molecolare:499.52MK-5108
CAS:MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Formula:C22H21ClFN3O3SPurezza:99.22%Colore e forma:SolidPeso molecolare:461.94Dehydrocorydaline nitrate
CAS:DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Formula:C22H24N2O7Purezza:99.79% - 99.92%Colore e forma:SolidPeso molecolare:428.44Ref: TM-T2S2362
1mg89,00€5mg205,00€10mg334,00€25mg552,00€50mg782,00€100mg1.054,00€200mg1.414,00€1mL*10mM (DMSO)243,00€PF-03814735
CAS:PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.Formula:C23H25F3N6O2Purezza:98%Colore e forma:SolidPeso molecolare:474.48SCH-1473759 hydrochloride
CAS:SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Formula:C20H27ClN8OSPurezza:98.29%Colore e forma:SolidPeso molecolare:463Ref: TM-T12864
2mg343,00€5mgPrezzo su richiesta10mgPrezzo su richiesta1mL*10mM (DMSO)Prezzo su richiestaGSK2807 Trifluoroacetate
CAS:GSK2807 Trifluoroacetate is a selective and SAM-competitive inhibitor of SMYD3 (Ki: 14 nM; IC50: 130 nM).Formula:C21H33F3N8O7Purezza:99.95%Colore e forma:SolidPeso molecolare:566.53NVP-BSK805
CAS:NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.Formula:C27H28F2N6OPurezza:98%Colore e forma:SolidPeso molecolare:490.55Acedapsone
CAS:Acedapsone has antimalarial and antimicrobial action, but is mainly used as a depot leprostatic agent.Formula:C16H16N2O4SPurezza:98%Colore e forma:SolidPeso molecolare:332.37Tazemetostat trihydrochloride
CAS:Tazemetostat trihydrochloride, an EZH2 inhibitor, orally active, IC50: 4nM (rat), Ki: 2.5nM (human), effective in peptide and nucleosome assays.Formula:C34H47Cl3N4O4Purezza:98%Colore e forma:SolidPeso molecolare:682.12(R)-Dihydrolipoic acid
CAS:(R)-Dihydrolipoic acid, the biochemically significant R-enantiomer, partakes in biochemical transformations.Formula:C8H16O2S2Purezza:98%Colore e forma:SolidPeso molecolare:208.33TETi76
CAS:TETi76 is an orally active inhibitor from the TET family, demonstrating IC50 values of 1.5, 9.4, and 8.8 μM against TET1, TET2, and TET3, respectively. The compound competitively binds to the active sites of TET enzymes, reducing cytosine hydroxymethylation and restricting clonal growth in mutated TET2 in vitro and in vivo, without affecting the growth of normal hematopoietic progenitor cells. TETi76 is utilized in leukemia research.Formula:C10H16O5Colore e forma:SolidPeso molecolare:216.232-PADQZ
CAS:DPQ is an antiviral compound.Formula:C14H19N5O2Purezza:98%Colore e forma:White PowderPeso molecolare:289.33Diethyl bipy55'DC
CAS:"Diethyl bipy55'DC blocks CP4H, crucial for collagen stability via hydroxylation in cells."Formula:C16H16N2O4Purezza:98%Colore e forma:SolidPeso molecolare:300.31GSK 4027
CAS:GSK 4027 is a PCAF/GCN5 bromodomain chemical probe. In a time-resolved fluorescence resonance energy transfer (TR-FRET) assay, it has a pIC50 of 7.4±0.11 for PCAF.Formula:C17H21BrN4OColore e forma:SolidPeso molecolare:377.28Nicotinamide-d4
CAS:Nicotinamide-d4 is a deuterium-labelled compound of nicotinamide for isotope tracing. Nicotinamide, a vitamin B3 derivative, inhibits SIRT1 and SIRT2.Formula:C6H2D4N2OPurezza:99.746%Colore e forma:SolidPeso molecolare:126.15
