Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2611 prodotti di "Cromatina/Epigenetica"
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I-BET787
CAS:I-BET787, an orally active pan-BET bromodomain inhibitor, has demonstrated efficacy in murine inflammation models.Formula:C16H20ClN3O2Colore e forma:SolidPeso molecolare:321.80PKCTheta-IN-2
CAS:PKCTheta-IN-2 (compound 14) is a potent and selective PKCθ inhibitor (IC50 = 0.25 nM) that suppresses IL-2 production in mice (IC50 = 682 nM).Formula:C24H23N5O2Purezza:99.38%Colore e forma:SolidPeso molecolare:413.47Ref: TM-T201189
1mgPrezzo su richiesta5mgPrezzo su richiesta10mg92,00€25mg177,00€50mg268,00€100mg432,00€KAT6-IN-1
CAS:KAT6-IN-1 (compound E) is a selective, orally available inhibitor of histone acetyltransferases KAT6A and KAT6B, exhibiting antitumour activity for cancer.Formula:C19H18N4O5SPurezza:99.86%Colore e forma:SolidPeso molecolare:414.43AdipoR agonist 1
CAS:AdipoR agonist 1 (Compound 112254), acting as an agonist for the adiponectin receptor (AdipoR), stimulates transcriptional regulators including peroxisome proliferator-activated receptors (PPARs), peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α), sirtuin 1 (SIRT1), and adenylate-activated protein kinase (AMPK). It is employed in the field of preventive doping research.Formula:C26H35N3O3Colore e forma:SolidPeso molecolare:437.57BG48
CAS:BG48, a COMET probe, enables precise optical epigenetic control and photochromically blocks human histone deacetylases with visible light.Formula:C25H23N5OSColore e forma:SolidPeso molecolare:441.55BG14
CAS:BG14: High-res optical epigenetic control; photo-inhibits human histone deacetylases with visible light.Formula:C21H21N5OColore e forma:SolidPeso molecolare:359.433BChE/HDAC6-IN-2
CAS:BChE/HDAC6-IN-2 is an inhibitor of BChE and HDAC6 with neuroprotective and ROS scavenging activity and a metal ion co-agonist and inhibits tau phosphorylation.Formula:C27H30N4O4Purezza:98.47%Colore e forma:SoildPeso molecolare:474.55BRD 4354 ditrifluoroacetate
BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and 1.88 μM).Formula:C25H25ClF6N4O5Purezza:98%Colore e forma:SolidPeso molecolare:610.93BG47
CAS:BG47: a COMET probe for precise optical epigenetic control, inhibits histone deacetylases with light.Formula:C25H22N4O2SColore e forma:SolidPeso molecolare:442.54KR-39038
CAS:KR-39038 is an oral GRK5 inhibitor for heart failure research; blocks HDAC5 pathway, IC50: 0.02 μM, fights cardiac hypertrophy.Formula:C24H32ClFN6OColore e forma:SolidPeso molecolare:475.00HDAC6-IN-27
CAS:HDAC6-IN-27 (compound 8C), an HDAC inhibitor, exhibits IC 50 values of 15.9 nM, 136.5 nM, and 6180.2 nM against HDAC6, HDAC8, and HDAC1, respectively. It also demonstrates potent antiparasitic effects [1].Formula:C15H15N3O4Colore e forma:SolidPeso molecolare:301.3HDAC2-IN-2
CAS:HDAC2-IN-2 (compound 124) acts as an HDAC2 inhibitor, exhibiting a Kd value ranging from 0.1-1 μM.Formula:C18H15N3O3SColore e forma:SolidPeso molecolare:353.40GSK-J1 lithium salt
CAS:GSK-J1 lithium salt is an effective inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with an IC 50 of 60 nM for KDM6B.Formula:C22H22LiN5O2Purezza:98%Colore e forma:SolidPeso molecolare:395.38Guanosine-5'-triphosphate disodium salt
CAS:5'-GTP disodium salt boosts myogenic differentiation and fuels cellular processes.Formula:C10H14N5Na2O14P3Purezza:95.69% - 99.96%Colore e forma:Odorless White SolidPeso molecolare:567.14Asteltoxin
CAS:Asteltoxin is a useful organic compound for research related to life sciences. The catalog number is T124203 and the CAS number is 79663-49-3.Formula:C23H30O7Colore e forma:SolidPeso molecolare:418.486CrBKA
CAS:CrBKA is a fluorogenic small-molecule substrate of SIRT6 with weak activity [1] .Formula:C28H31N3O6Colore e forma:SolidPeso molecolare:505.56(3S,4S)-Tofacitinib
CAS:(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.Formula:C16H20N6OPurezza:98%Colore e forma:SolidPeso molecolare:312.37UNC0224
CAS:UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.Formula:C26H43N7O2Purezza:99.80%Colore e forma:SolidPeso molecolare:485.67Phorbol 12,13-dibutyrate
CAS:Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.Formula:C28H40O8Purezza:99.32% - 99.37%Colore e forma:SolidPeso molecolare:504.61Ref: TM-T16526
1mg58,00€5mg160,00€10mg268,00€25mg530,00€50mg827,00€100mg1.314,00€200mg1.773,00€1mL*10mM (DMSO)170,00€TAK-285
CAS:TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Formula:C26H25ClF3N5O3Purezza:99.73%Colore e forma:SolidPeso molecolare:547.96Ref: TM-T6039
1mg38,00€5mg80,00€10mg120,00€25mg216,00€50mg354,00€100mg512,00€200mg727,00€1mL*10mM (DMSO)96,00€
