Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2595 prodotti di "Cromatina/Epigenetica"
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KDM2/7-IN-1
CAS:KDM2/7-IN-1 is a selective histone demethylase inhibitor (IC50s: 0.2–>120 μM) that inhibits HeLa and KYSE-150 cell proliferation, epigenetic and cancer.Formula:C15H27NO4Purezza:99.87%Colore e forma:SolidPeso molecolare:285.38BRM/BRG1 ATP Inhibitor-4
CAS:BRM/BRG1 ATP Inhibitor-4, a potent inhibitor of BRG1/BRM, is utilized in the research of cancers and BAF complex-related disorders.Formula:C25H32N6O3SColore e forma:SolidPeso molecolare:496.62Bromodomain inhibitor-10
CAS:Bromodomain inhibitor-10 (compound 128) suppresses BRD4-1/2 with Kd 15 nM/2.5 μM and curbs IL12p40 production.Formula:C20H20N4O3Colore e forma:SolidPeso molecolare:364.4DPQ
CAS:DPQ inhibits PARP-1, aids in neuroprotection, restores ATP, and lessens neuronal injury from NMDA.
Formula:C18H26N2O2Purezza:98%Colore e forma:SolidPeso molecolare:302.41DFPM
CAS:DFPM activates plant resistance, inhibits root growth, reduces Col-0 root cell viability, and is light-sensitive in water.Formula:C16H15Cl2NOSColore e forma:SolidPeso molecolare:340.27Metformin icosapent
CAS:Metformin icosapent activates AMPK, enhancing insulin sensitivity and reducing glucose absorption for better glycemic control.Formula:C24H41N5O2Colore e forma:SolidPeso molecolare:431.62UMB-32
CAS:UMB-32: Potent, selective BRD4 inhibitor, Kd 550 nM, IC50 637 nM, also targets TAF1.Formula:C21H23N5OColore e forma:SolidPeso molecolare:361.44Binucleine 2
CAS:Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.Formula:C13H11ClFN5Colore e forma:SolidPeso molecolare:291.71YUKA1
CAS:YUKA1, a cell-permeable KDM5A inhibitor with a weak effect on KDM5C, increase H3K4me3 and inhibit the proliferation, prevent drug-resistant.Formula:C13H16N4O2SPurezza:99.85%Colore e forma:SolidPeso molecolare:292.36Ref: TM-T17278
1mg105,00€5mg250,00€10mg409,00€25mg802,00€50mg1.224,00€100mg1.783,00€200mg2.457,00€1mL*10mM (DMSO)268,00€NSD3-IN-1
CAS:NSD3-IN-1, a histone methyltransferase NSD3 inhibitor, demonstrates an IC50 of 28.58 μM.Formula:C13H13N5OSColore e forma:SolidPeso molecolare:287.34UL04
CAS:UL04 is an inhibitor of CREBBP bromodomain.Formula:C18H17NO5Colore e forma:SolidPeso molecolare:327.33K00135
CAS:K00135 (IMIDAZOPYRIDAZIN 1) is a selective inhibitor of Pim kinases and can be used in studies about gastric cancer and antileukemic therapeutics.Formula:C18H18N4OPurezza:98.16%Colore e forma:SolidPeso molecolare:306.36CPI-905
CAS:CPI-905 is a potent and selective EZH2 inhibitor with IC50 value of 39.5 nM.Formula:C18H20N2O5Colore e forma:SolidPeso molecolare:344.36SIRT5 inhibitor 4
CAS:SIRT5 inhibitor 4 (compound 11) is a dose-dependent and selective SIRT5 (Sirtuin5) inhibitorand no inhibitory effect on SIRT1/2/3,anticancer.Formula:C18H15N3O4SPurezza:99.97%Colore e forma:SolidPeso molecolare:369.39ZLD1039
CAS:ZLD1039, an oral EZH2 inhibitor, shows strong PRC2 inhibition at low nanomolar IC50s, and halts breast cancer growth and spread.Formula:C36H48N6O3Purezza:99.5%Colore e forma:SolidPeso molecolare:612.8EZM 2302
CAS:EZM 2302 (GSK3359088) is a selective, and orally available arginine methyltransferase CARM1 inhibitor (IC50: 6 nM).Cost-effective and quality-assured.Formula:C29H37ClN6O5Purezza:97.47% - ≥98%Colore e forma:SolidPeso molecolare:585.09PIM1-IN-6
CAS:PIM1-IN-6 (5h) inhibits PIM-1 (IC50: 0.60 μM) and is cytotoxic to HCT-116 (IC50: 1.51 μM) and MCF-7 cells (IC50: 15.2 μM).Formula:C21H18N6O4Colore e forma:SolidPeso molecolare:418.41LT052
CAS:LT052 is a BET BD1 inhibitor with anti-inflammatory activity. It mediates the BRD4/NF-κB/NLRP3 signaling inflammatory pathway.Formula:C22H19N5O4SPurezza:98.82%Colore e forma:SolidPeso molecolare:449.48SGC6870
CAS:SGC6870 is a novel potent, selective, and cell-active inhibitor of PRMT6 with IC50 of 77 ± 6 nM, being selective over all other PRMTs and 23 methyltransferases.Formula:C23H21BrN2O2SColore e forma:SolidPeso molecolare:469.39DCE_42
CAS:DCE_42 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.Formula:C22H19N9O2SPurezza:98%Colore e forma:SolidPeso molecolare:473.51
