Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2553 prodotti di "Cromatina/Epigenetica"
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NN-390
CAS:NN-390: selective HDAC6 inhibitor, IC50 9.8 μM, blood-brain barrier penetrant, potential for metastatic group 3 neural tube cancer research.Formula:C17H16F4N2O4SColore e forma:SolidPeso molecolare:420.38AA-CW236
CAS:AA-CW236 is a covalent inhibitor of human O(6)-alkylguanine DNA methyltransferase (MGMT).Formula:C17H16ClF3N4O2Colore e forma:SolidPeso molecolare:400.78Antiproliferative agent-17
CAS:Antiproliferative Agent-17 exhibits both antimicrobial properties against Gram-positive bacteria and anticancer activity [1].Formula:C26H28N2OSColore e forma:SolidPeso molecolare:416.58103D5R
CAS:103D5R selectively inhibits hif-1α, reducing its levels in hypoxia or with cobalt ions, dose- and time-dependently.Formula:C20H21N3O2Colore e forma:SolidPeso molecolare:335.4BET bromodomain inhibitor 2
CAS:BET bromodomain inhibitor 2 is a potent inhibitor of the BET-type bromodomain (IC50: 14.1 μM).Formula:C23H30N2O5SColore e forma:SolidPeso molecolare:446.56GDC-4379
CAS:GDC-4379 is a JAK1 inhibitor that can be used to study asthma.Formula:C21H18ClF2N7O3Colore e forma:SolidPeso molecolare:489.86TYK2-IN-11
CAS:TYK2-IN-11 (5B) selectively inhibits TYK2 (IC50: 0.016 nM) and JAK1 (IC50: 0.31 nM), aiding autoimmune and inflammatory disease research.Formula:C18H17N5O3SColore e forma:SolidPeso molecolare:383.42AChE/HDAC-IN-1
CAS:COX-2-IN-23 (A10) inhibits AChE & HDAC (IC50s: 0.12 & 0.23 nM), has antioxidant/metal-binding traits, and is used in Alzheimer's research.Formula:C26H27ClN4O3Colore e forma:SolidPeso molecolare:478.97DNMT3A-IN-1
CAS:DNMT3A-IN-1 is a potent, selective DNMT3A inhibitor with KI 9.16-18.85 μM (AdoMet) and 11.37-23.34 μM (poly dI-dC).Formula:C30H38N6O4Colore e forma:SolidPeso molecolare:546.66CAY10685
CAS:CAY10685, a CPTH2 analog with an alkyne for click reactions, inhibits NAT10 to study cancer-related chromatin changes.Formula:C17H16ClN3SColore e forma:SolidPeso molecolare:329.85BRD4 Inhibitor-25
BRD4 Inhibitor-25 blocks BRD4 (BD1: IC50 0.82 μM, BD2: 1.94 μM), induces cell death in ovarian cancer, used in cancer research.Formula:C29H27N5O6SColore e forma:SolidPeso molecolare:573.62HDAC6-IN-10
CAS:HDAC6-IN-10 is a potent HDAC6 inhibitor with 0.73 nM IC50, highly selective, and hinders multiple myeloma cell growth.Formula:C21H20N4O4Colore e forma:SolidPeso molecolare:392.41J1038
CAS:J1038 is a novel Histone Deacetylase 8 (HDAC8) Inhibitor .Formula:C10H10N2O3SColore e forma:SolidPeso molecolare:238.26HDAC8/BRPF1-IN-1
CAS:Compound 23a, dual HDAC8/BRPF1 inhibitor: IC50 HDAC8 = 443 nM, Kd BRPF1 = 67 nM; weak against HDAC1/6.Formula:C19H19N3O6SColore e forma:SolidPeso molecolare:417.44HDAC6-IN-14
HDAC6-IN-14, an inhibitor of HDAC6 (HDAC), exhibits high selectivity with an IC50 value of 42 nM, demonstrating over 100-fold selectivity compared to HDAC1,Formula:C24H30FN3O4Colore e forma:SolidPeso molecolare:443.51BI-831266
CAS:BI-831266 is a potent and selective Aurora kinase B inhibitor.Formula:C27H38ClN7O2Colore e forma:SolidPeso molecolare:528.09HDAC-IN-41
CAS:HDAC-IN-41 is a selective class I HDAC inhibiting HDAC1, 2, & 3 with IC50: 0.62-1.46 µM; oral use; has NO-release.Formula:C20H22N4O6SColore e forma:SolidPeso molecolare:446.48PARP11 inhibitor ITK7
CAS:ITK7 is a potent, selective PARP11 inhibitor with an IC50 of 14 nM, useful for cellular localization research.Formula:C17H14N4OSColore e forma:SolidPeso molecolare:322.38HDAC1/MAO-B-IN-1
CAS:HDAC1/MAO-B-IN-1 is a selective Alzheimer’s research inhibitor with IC50s: HDAC1 (21.4 nM) & MAO-B (99 nM); crosses the blood-brain barrier.Formula:C18H17ClN2O2Colore e forma:SolidPeso molecolare:328.79Aurora kinase inhibitor-9
CAS:Aurora kinase inhibitor-9 (9d) targets AURKA/B with IC50: 0.093 μM for A and 0.09 μM for B, with wide anti-proliferative effects.Formula:C19H17Cl2N3O4SColore e forma:SolidPeso molecolare:454.33
