Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2553 prodotti di "Cromatina/Epigenetica"
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BET-IN-7
CAS:BET-IN-7 is a potent BET inhibitor with a Ki of 12.27 μM and Kd of 89.3 μM, useful in sepsis research.Formula:C18H12ClN3OSColore e forma:SolidPeso molecolare:353.83MAT2A-IN-5
CAS:MAT2A-IN-5 inhibits MAT2A in tumors, curbing growth in gastric, colon, liver, and pancreatic cancers.Formula:C17H12ClF3N2OColore e forma:SolidPeso molecolare:352.74SIRT6-IN-1
CAS:SIRT6-IN-1, a novel SIRT6 inhibitor, reduces glycemia and improves oral glucose tolerance in unfed wild-type mice.Formula:C19H14N4O5SColore e forma:SolidPeso molecolare:410.4OUL245
CAS:OUL245: A selective PARP2 inhibitor (IC50=44nM), also inhibits other PARPs/TNKS (IC50=2.9-8.8μM).Formula:C8H5N3OSColore e forma:SolidPeso molecolare:191.21HDAC6-IN-15
HDAC6-IN-15: selective HDAC6 inhibitor, IC50 of 38.2 nM, for cancer and neurodegenerative research.Formula:C25H28FFeN3O2Colore e forma:SolidPeso molecolare:477.35NSC 698600
CAS:NSC 698600 is a potent inhibitor of PCAF(p300/CBP-associated factor) with IC 50 of 6.51 μM that shows good inhibition activity of cancer cell proliferation [1].Formula:C14H12N2O2SColore e forma:SolidPeso molecolare:272.32CYP51/HDAC-IN-1
CAS:Orally active CYP51/HDAC-IN-1 dual inhibitor targets virulence factors and resistance genes; effective against Candidiasis and Cryptococcal meningitis.Formula:C30H40F2N6O4Colore e forma:SolidPeso molecolare:586.67CBB1003
CAS:CBB1003 is a new inhibitor of histone demethylase LSD1 (IC50: 10.54 μM).Formula:C25H31N9O4Purezza:98%Colore e forma:SolidPeso molecolare:521.57SPC-180002
CAS:SPC-180002, a dual SIRT1/3 inhibitor, exhibits IC50 values of 1.13 and 5.41 μM for SIRT1 and SIRT3, respectively.Formula:C18H23NO4Purezza:98%Colore e forma:SolidPeso molecolare:317.38PKN1/2-IN-1
CAS:PKN1/2-IN-1 is a potent and selective PKN2 inhibitor, membrane permeability and anticancer.Protein kinase N proteins (PKN) are effectors of Rho GTPases.Formula:C14H15N3OPurezza:99.72%Colore e forma:SolidPeso molecolare:241.29Ref: TM-T60339
2mg137,00€5mg222,00€10mg356,00€25mg708,00€50mg1.063,00€100mg1.674,00€1mL*10mM (DMSO)245,00€HPCG
CAS:HPCG is an inhibitor of HIF-1α prolyl hydroxylase.Formula:C8H8N2O4Colore e forma:SolidPeso molecolare:196.16HDAC-IN-28
CAS:HDAC-IN-28 is a novel inhibitor of HDAC that significantly inhibits tumour growth and metastasis.Formula:C23H26N4O4SColore e forma:SolidPeso molecolare:454.54Y08175
CAS:Y08175, a CBP Bromodomain inhibitor, IC50: 37 nM (AlphaScreen), 178.15 nM (HTRF). Useful in prostate cancer research.Formula:C23H19FN4O5Colore e forma:SolidPeso molecolare:450.42Sirtuin modulator 4
CAS:Sirtuin modulator 4 inhibits SIRT1 (EC50: 51-100 μM), may extend cell life and prevent diseases like diabetes and cancer.Formula:C18H10N2O2SColore e forma:SolidPeso molecolare:318.35iBRD4-BD1
CAS:iBRD4-BD1 inhibits BRD4 bromodomain selectively with 12 nM IC50, useful in inflammation and cancer research.Formula:C29H30F3N5OColore e forma:SolidPeso molecolare:521.58ZIKV-IN-2
CAS:ZIKV-IN-2 blocks ZIKV replication, is a strong NS5 MTase inhibitor (IC50: 38.86 μM), and aids Zika virus research.Formula:C39H42O4Colore e forma:SolidPeso molecolare:574.75CEP-8983
CAS:CEP-8983 is a PARP inhibitor potentially for the treatment of solid tumours.Formula:C18H14N2O3Purezza:98%Colore e forma:SolidPeso molecolare:306.32JS1310
CAS:JS1310 is a selective PRMT7 inhibitor (IC50: 5 μM against human PRMT7). JS1310 has shown anti-cancer effects on different cancer cells.Formula:C23H22FN5O3Colore e forma:SolidPeso molecolare:435.45ARTD10/PARP10-IN-2
CAS:ARTD10/PARP10-IN-2: A potent, non-selective PARP inhibitor, IC50: ARTD10/PARP10 (2.0μM), ARTD1/PARP1 (9.7μM).Formula:C12H13N3O3Colore e forma:SolidPeso molecolare:247.25OHM1
CAS:OHM1, an analog of HIF1α CTAD, effectively inhibits the interaction between HIF1α CTAD and p300/CBP by targeting the CH1 domain with a binding affinity of 0.53Formula:C24H42N6O5Colore e forma:SolidPeso molecolare:494.63
