Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2553 prodotti di "Cromatina/Epigenetica"
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Tyk2-IN-5
CAS:Tyk2-IN-5 is a selective and orally active inhibitor of Tyk2 JH2 (Ki: 0.086 nM for Tyk2 JH2; IC50: 25 nM for IFNα).Formula:C21H19FN8O2Purezza:98%Colore e forma:SolidPeso molecolare:434.43PF-739
CAS:PF-739 is an AMPK agonist that has been shown to activate AMPK in hepatocytes and skeletal muscle.Formula:C23H23ClN2O5Purezza:98%Colore e forma:SolidPeso molecolare:442.89HDAC-IN-29
CAS:HDAC-IN-29 (compound 13b) is a potent pan- HDAC inhibitor with antitumor activity.Formula:C20H23N3O4SColore e forma:SolidPeso molecolare:401.48Aurora kinase inhibitor-10
CAS:Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.Formula:C21H19F5N6O4SColore e forma:SolidPeso molecolare:546.47MT477
CAS:MT477 inhibits PKC-α, impairs Ras/ERK1/2 phosphorylation, induces apoptosis, and reduces proliferation in various cancer cells.Formula:C31H30N2O12S3Colore e forma:SolidPeso molecolare:718.77IACS-9571
CAS:IACS-9571 is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).Formula:C32H42N4O8SPurezza:98%Colore e forma:SolidPeso molecolare:642.76YM-53601
CAS:YM-53601 is an SQS inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits FDFT1.Formula:C21H22ClFN2OPurezza:99.65%Colore e forma:SolidPeso molecolare:372.86Rucaparib camsylate
CAS:Rucaparib camsylate, a PARP-1, -2, -3 inhibitor (Ki=1.4 nM for PARP-1) & H6PD blocker, may treat resistant prostate cancer.Formula:C19H18FN3O·xC10H16O4SColore e forma:SolidMI-2-2
CAS:MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.Formula:C17H20F3N5S2Purezza:99.65%Colore e forma:SolidPeso molecolare:415.5HIF-PHD-IN-2
CAS:HIF-PHD-IN-2 (compound 25) is a highly effective PHD inhibitor, displaying IC50 values below 100 nM for PHD1, PHD2, and PHD3 [1].Formula:C17H15N5O3SColore e forma:SolidPeso molecolare:369.4Y08284
CAS:Y08284: selective CBP bromodomain inhibitor, IC50: 4.21 nM, oral. Halts prostate cancer cell growth; anti-tumor.Formula:C26H25FN4O4Colore e forma:SolidPeso molecolare:476.5HDAC/CK2-IN-1
CAS:HDAC/CK2-IN-1 (compound 38) acts as an inhibitor of HDAC1 (IC 50 = 1.46 μM), HDAC6 (IC 50 = 0.66 μM), and CK2 (IC 50 = 3.67 μM). It demonstrates promising antiproliferative effects on various cell lines, including Jurkat, MCF-7, HCT-116, and HL-60.Formula:C15H18Br4N4O2Colore e forma:SolidPeso molecolare:605.95HDAC/NAMPT-IN-1
CAS:HDAC/NAMPT-IN-1 (compound 39h) simultaneously inhibits HDAC and NAMPT, exhibiting IC 50 values ranging from 0.72 to 37081 nM for HDAC and 1618 nM for NAMPT [1].Formula:C19H21N5O2Colore e forma:SolidPeso molecolare:351.4Bizine
CAS:Bizine, a Phenelzine analogue, selectively inhibits LSD1 (Ki=59 nM), modulates histone methylation in cancer, and may have neuroprotective uses.Formula:C18H23N3OColore e forma:SolidPeso molecolare:297.39M133
CAS:M133 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.Formula:C23H24N4OS2Colore e forma:SolidPeso molecolare:436.59Furamidine dihydrochloride
CAS:Furamidine dihydrochloride is a cell-permeable, selective PRMT1 inhibitor that also binds AT-rich DNA. It blocks proliferation in leukemia cell lines.Formula:C18H18Cl2N4OPurezza:98.16%Colore e forma:SolidPeso molecolare:377.27Peficitinib hydrobromide
CAS:Peficitinib hydrobromide is used in the treatment of Psoriasis and Rheumatoid Arthritis.Formula:C18H23BrN4O2Colore e forma:SolidPeso molecolare:407.312GRK6-IN-1
CAS:GRK6-IN-1 (compound 18) is a potent GRK6 blocker, with an IC50 of 120 nM, showing promise for multiple myeloma research.Formula:C22H23ClN6O2Purezza:99.37%Colore e forma:SolidPeso molecolare:438.91Ref: TM-T62518
1mg57,00€5mg120,00€10mg188,00€25mg432,00€50mg747,00€100mg1.216,00€1mL*10mM (DMSO)133,00€Procainamide
CAS:Procainamide: DNMT1 inhibitor, Class 1A antiarrhythmic, promising for cancer and arrhythmia research.Formula:C13H21N3OPurezza:99.79% - 99.92%Colore e forma:SolidPeso molecolare:235.33Cedazuridine
CAS:Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.Formula:C9H14F2N2O5Purezza:99.66%Colore e forma:SolidPeso molecolare:268.21
