Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2553 prodotti di "Cromatina/Epigenetica"
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LSD1-IN-13
CAS:LSD1-IN-13, an oral LSD1 blocker (IC50: 24.43 nM), boosts CD86 (EC50: 470 nM), and triggers AML cell line differentiation.Formula:C23H29N3O2SColore e forma:SolidPeso molecolare:411.56EZH2-IN-7
CAS:EZH2-IN-7 inhibits EZH2, reducing H3K27me3 and tumor growth (e.g., breast, prostate cancer, leukemia). Potential in cancer research.Formula:C31H37D2N5O3SColore e forma:SolidPeso molecolare:563.755-Aza-4'-thio-2'-deoxycytidine
CAS:5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd), a sulfur-containing deoxy-cytidine analog, serves as an orally active inhibitor of DNA methyltransferase I (DNMT1). It exhibits potential antitumor effects and DNA hypomethylating properties [1].Formula:C8H12N4O3SColore e forma:SolidPeso molecolare:244.27G9a-IN-2
CAS:G9a-IN-2 (Compound 7i) is an inhibitor of the histone methyltransferase G9a, with an IC50 of 0.024 μM. It can reduce the levels of H3K9me2 and induce the expression of γ-globin mRNA. G9a-IN-2 shows potential for improving Sickle Cell Disease (SCD).Formula:C30H42N4O4Colore e forma:SolidPeso molecolare:522.68FAK/aurora kinase-IN-1
CAS:FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].Formula:C23H24ClN7O3Colore e forma:SolidPeso molecolare:481.93OM-137
CAS:OM137 inhibits Aurora kinases, impedes cell growth at high doses, and enhances low-dose paclitaxel effects.Formula:C13H14N4O3SColore e forma:SolidPeso molecolare:306.34HDAC-IN-30
CAS:HDAC-IN-30 is a potent HDAC inhibitor targeting HDAC1, 2, 3, 6, and 8 with strong antitumor efficacy.
Formula:C22H23N5O3Colore e forma:SolidPeso molecolare:405.45BI-9321
CAS:BI-9321: Selective NSD3-PWWP1 antagonist, Kd 166 nM. Inactive against NSD2-PWWP1/NSD3-PWWP2.Formula:C22H21FN4Purezza:98%Colore e forma:SolidPeso molecolare:360.43SHP2/HDAC-IN-1
CAS:SHP2/HDAC-IN-1: dual SHP2/HDAC inhibitor, IC50: 20.4 nM/25.3 nM, boosts antitumor immunity, aids cancer immunotherapy research.Formula:C34H35Cl2N7O3Colore e forma:SolidPeso molecolare:660.59EZM 2302
CAS:EZM 2302 (GSK3359088) is a selective, and orally available arginine methyltransferase CARM1 inhibitor (IC50: 6 nM).Cost-effective and quality-assured.Formula:C29H37ClN6O5Purezza:97.47% - ≥98%Colore e forma:SolidPeso molecolare:585.09TC-E 5001
CAS:dual tankyrase (TNKS) inhibitorFormula:C20H19N5O3SPurezza:98%Colore e forma:SolidPeso molecolare:409.46BiBET
CAS:BiBET is a potent, selective, bivalent inhibitor of BET bromodomains.Formula:C26H30N10O3Colore e forma:SolidPeso molecolare:530.58NSD3-IN-1
CAS:NSD3-IN-1, a histone methyltransferase NSD3 inhibitor, demonstrates an IC50 of 28.58 μM.Formula:C13H13N5OSColore e forma:SolidPeso molecolare:287.34HPB
CAS:HPB is a selective HDAC6 deacetylase inhibitorFormula:C18H20N2O4Colore e forma:SolidPeso molecolare:328.36BET-BAY 002 (S enantiomer)
CAS:The S-enantiomer of BET-BAY 002, referred to as BET-BAY 002 S enantiomer, is a potent inhibitor of BET (Bromodomain and Extra-Terminal motif proteins).Formula:C22H18ClN5OPurezza:98%Colore e forma:SolidPeso molecolare:403.86Bromodomain IN-1
CAS:Bromodomain IN-1 is an inhibitor of Bromodomain.Formula:C22H23ClN4O3SPurezza:98%Colore e forma:SolidPeso molecolare:458.96ZIKV-IN-3
CAS:ZIKV-IN-3, an andrographolide derivative, inhibits ZIKV NS5 MTase (IC50: 18.34 μM) and replication. Used for Zika virus research.Formula:C39H41NO4Colore e forma:SolidPeso molecolare:587.75NVS-BET-1
CAS:NVS-BET-1 is a BET bromodomain inhibitor. NVS-BET-1 can regulate keratinocyte plasticity.Formula:C22H21ClN4O2Colore e forma:SolidPeso molecolare:408.88JAK3/BTK-IN-2
CAS:JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.
Formula:C25H32N8O2Purezza:99.64% - 99.87%Colore e forma:SolidPeso molecolare:476.57HIF-1α-IN-3
CAS:HIF-1α-IN-3, also known as Compound (S)-3f, is a hypoxia-selective inhibitor of HIF-1α. It exhibits potent antiestrogenic activity [1].Formula:C19H17N5O2Colore e forma:SolidPeso molecolare:347.37
