Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2547 prodotti di "Cromatina/Epigenetica"
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β-NF-JQ1
CAS:β-NF-JQ1 is a PROTAC that recruits aryl hydrocarbon receptor E3 (AhR E3) ligase to target proteins.Formula:C45H42ClN5O6SPurezza:97.58% - 99.15%Colore e forma:SolidPeso molecolare:816.36CARM1-IN-1
CAS:CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.Formula:C26H21Br2NO3Purezza:98.24%Colore e forma:SolidPeso molecolare:555.26Ref: TM-T10682L
1mg37,00€5mg88,00€10mg127,00€25mg250,00€50mg406,00€100mg632,00€200mg883,00€1mL*10mM (DMSO)97,00€Bisaramil hydrochloride
CAS:Bisaramil hydrochloride (Bisaramil) is an antiarrhythmic compound that inhibits free radical production.Formula:C17H24Cl2N2O2Purezza:98.64% - 99.48%Colore e forma:SolidPeso molecolare:359.29SK-575
CAS:SK-575 is a potent PARP1-degrading agent effective against BRCA1/2 mutant cancers, even at low doses, and enhances tumor inhibition in mice.Formula:C47H53FN8O8Purezza:99.39%Colore e forma:SolidPeso molecolare:876.97AGI-43192
CAS:AGI-43192: potent MAT2A inhibitor, crosses blood-brain barrier, may help study SAM in CNS and treat cancer.
Formula:C23H16ClF3N6OPurezza:99.89%Colore e forma:SolidPeso molecolare:484.86OUL232
CAS:OUL232 is a potent single ARTs PARP7, PARP10, PARP11, PARP12, PARP14 and PARP15 inhibitor for cancer and tumour research.Formula:C10H10N4O2SPurezza:99.04%Colore e forma:SolidPeso molecolare:250.28CD532
CAS:CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.Formula:C26H25F3N8OPurezza:99.99%Colore e forma:SolidPeso molecolare:522.52ACY-957
CAS:ACY-957: Oral HDAC1/2 inhibitor (IC50: HDAC1=7nM, HDAC2=18nM, HDAC3=1300nM); inactive on HDAC4/5/6/7/8/9.Formula:C24H23N5OSPurezza:99.79%Colore e forma:SolidPeso molecolare:429.54Ref: TM-T10245
1mg90,00€2mg136,00€5mg230,00€10mg281,00€25mg432,00€50mg612,00€100mg802,00€1mL*10mM (DMSO)251,00€Izencitinib
CAS:Izencitinib (JNJ-8398) is a JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.Formula:C22H26N8Purezza:99.82%Colore e forma:SolidPeso molecolare:402.50Ref: TM-T35898
1mg84,00€5mg177,00€10mg281,00€25mg567,00€50mg888,00€100mg1.431,00€200mg1.963,00€1mL*10mM (DMSO)195,00€Crebinostat
CAS:Crebinostat: potent HDAC inhibitor, boosts synapsin-1 in neurons, enhances memory and gene Egr1 expression in mice.Formula:C20H23N3O3Purezza:99.49%Colore e forma:SolidPeso molecolare:353.41PARP10-IN-2
CAS:PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 and
Formula:C14H10N2O2Purezza:99.27%Colore e forma:SolidPeso molecolare:238.24ML192
CAS:ML192 (CID1434953) is a selective GPR55 ligand antagonist.Formula:C20H22N4O2SPurezza:99.17%Colore e forma:SolidPeso molecolare:382.48Ref: TM-T33452
1mg34,00€5mg71,00€10mg104,00€25mg172,00€50mg249,00€100mg350,00€200mg480,00€1mL*10mM (DMSO)92,00€BRD4 Inhibitor-20
CAS:BRD4 Inhibitor-20 is a potent bromodomain protein 4 (BRD4) inhibitor with oral activity.
Formula:C18H18N2O4SPurezza:99.84%Colore e forma:SolidPeso molecolare:358.41ACY-1083
CAS:ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor (IC50: 3 nM) and effectively reverses chemotherapy-induced peripheral neuropathy.Formula:C17H18F2N4O2Purezza:99.19% - 99.43%Colore e forma:SolidPeso molecolare:348.35Ref: TM-T10244
1mg144,00€5mg295,00€10mg504,00€25mg795,00€50mg1.108,00€100mg1.494,00€500mg2.997,00€1mL*10mM (DMSO)326,00€Demethyleneberberine chloride
CAS:Demethyleneberberine chloride, a natural mitochondria-targeted antioxidant, mitigates colitis in mice and suppresses inflammatory responses by blocking the NF-Formula:C19H18ClNO4Purezza:98%Colore e forma:SolidPeso molecolare:359.8JAK-IN-25
CAS:JAK-IN-25 (compound 19), a potent JAK inhibitor, exhibits IC50 values of 6 nM for TYK2, 21 nM for JAK1, 8 nM for JAK2, and 1051 nM for JAK3.Formula:C19H17N5O4Purezza:98%Colore e forma:SolidPeso molecolare:379.37FD1024
CAS:FD1024 is a potent PIM inhibitor, displaying inhibitory concentrations (IC50s) of 1.96 nM, 38.9 nM, and 4.17 nM for PIM1, PIM2, and PIM3, respectively.Formula:C21H20F2N4O2SPurezza:98%Colore e forma:SolidPeso molecolare:430.47CARM1-IN-3
CAS:CARM1-IN-3 (compound 17b) is a potent, selective inhibitor of co-activator associated arginine methyltransferase (CARM1), exhibiting IC50 values of 0.07 µM forFormula:C24H32N4O2Purezza:98%Colore e forma:SolidPeso molecolare:408.54Nesuparib
CAS:Nesuparib, a potent PARP/TNKS1 inhibitor, has antitumor properties and potential for treating various diseases.Formula:C23H24N6OPurezza:99.94%Colore e forma:SolidPeso molecolare:400.48Ref: TM-T61932
1mg94,00€5mg200,00€10mg319,00€25mg573,00€50mg782,00€100mg1.063,00€1mL*10mM (DMSO)220,00€TC-A 2317 hydrochloride
CAS:TC-A 2317 HCl inhibits Aurora A kinase (Ki 1.2 nM) over Aurora B (Ki 101 nM), displaying antitumor effects.Formula:C19H29ClN6OPurezza:98%Colore e forma:SolidPeso molecolare:392.93
