Sirtuina
Le sirtuine sono una famiglia di deacetilasi dipendenti dal NAD+ che svolgono un ruolo cruciale nella regolazione di processi cellulari come la riparazione del DNA, l'invecchiamento, il metabolismo e la resistenza allo stress. Le sirtuine influenzano la riparazione del DNA deacetilando le proteine coinvolte nelle vie di riparazione, modulandone così l'attività. Gli inibitori e gli attivatori delle sirtuine sono strumenti preziosi nella ricerca sull'invecchiamento, il cancro e le malattie metaboliche, dove la regolazione della riparazione del DNA e della longevità cellulare è di interesse. Presso CymitQuimica, offriamo una gamma di modulatori di sirtuine di alta qualità per supportare la tua ricerca sulla riparazione del DNA, l'invecchiamento cellulare e la regolazione metabolica.
Trovati 91 prodotti per "Sirtuina".
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SIRT5 inhibitor 3
CAS:SIRT5 inhibitor 3 is potent and competitive by inhibiting SIRT5 deacetylation, with potential in metabolic, cancer, neurodegenerative, cardiovascular .Formula:C22H12FN3O4Purezza:98%Colore e forma:Yellow SolidPeso molecolare:401.35ADTL-SA1215
CAS:ADTL-SA1215 is a SIRT3 activator with SIRT3 deacetylase activity for the study of triple negative breast cancer.Formula:C26H29I2NO3Purezza:99.23%Colore e forma:SolidPeso molecolare:657.32SRT 1720
CAS:SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.Formula:C25H23N7OSPurezza:98.80% - 98.84%Colore e forma:SolidPeso molecolare:469.56Ginkgolide C
CAS:Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body.Formula:C20H24O11Purezza:99.71% - 99.98%Colore e forma:White PowderPeso molecolare:440.40Thiomyristoyl
CAS:Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.Formula:C34H51N3O3SPurezza:99.16%Colore e forma:White SolidPeso molecolare:581.85Ref: TM-T3447
1mg54,00€2mg73,00€5mg92,00€10mg117,00€1mL*10mM (DMSO)117,00€25mg215,00€50mg360,00€100mg537,00€E1231
CAS:E1231 is an activator of SIRT1 . E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression.Formula:C21H21N3O3Purezza:98.45%Colore e forma:SolidPeso molecolare:363.41Suramin Sodium Salt
CAS:Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.Formula:C51H34N6Na6O23S6Purezza:97.47% - 99.97%Colore e forma:WhitePeso molecolare:1429.15SirReal2
CAS:SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.Formula:C22H20N4OS2Purezza:99.52% - 99.75%Colore e forma:SolidPeso molecolare:420.55Ref: TM-T6984
1mg37,00€2mg52,00€5mg74,00€1mL*10mM (DMSO)86,00€10mg102,00€25mg187,00€50mg295,00€100mg477,00€3-TYP
CAS:3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.Formula:C7H6N4Purezza:99.16% - >99.99%Colore e forma:SolidPeso molecolare:146.15Ref: TM-T4108
2mg37,00€5mg50,00€1mL*10mM (DMSO)50,00€10mg88,00€25mg158,00€50mg235,00€100mg371,00€200mg530,00€Nicotinamide riboside chloride
CAS:NR, also SRT647, is a B3 vitamin form; precursor to NAD+.Formula:C11H15ClN2O5Purezza:98.92% - 99.95%Colore e forma:SolidPeso molecolare:290.7SRT 1720 dihydrochloride
CAS:SRT 1720 dihydrochloride is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2 (EC1.5: 37 μM) and SIRT3 (EC1.5: 300 μM).Formula:C25H25Cl2N7OSPurezza:98.58%Colore e forma:SolidPeso molecolare:542.48Agrimol B
CAS:1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.Formula:C37H46O12Purezza:99.06% - ≥95%Colore e forma:Yellow SolidPeso molecolare:682.75Selisistat R-enantiomer
CAS:Selisistat R-enantiomer (EX-527 (R-enantiomer)) is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 μM).Formula:C13H13ClN2OPurezza:99.8%Colore e forma:White SolidPeso molecolare:248.71Ref: TM-T15263
1mg101,00€2mg150,00€5mg245,00€1mL*10mM (DMSO)269,00€10mg356,00€25mg597,00€50mg835,00€100mg1.108,00€Ophiopogonin D'
CAS:Ophiopogonin D' can activate SIRT1 in a dose-dependent manner. Ophiopogonin D' also noncompetitively inhibits UGT1A6 and UGT1A10.Formula:C44H70O16Purezza:99.69% - 99.77%Colore e forma:White SolidPeso molecolare:855.02Ref: TM-TN1071
1mg114,00€5mg289,00€10mg432,00€1mL*10mM (DMSO)533,00€25mg692,00€50mg945,00€100mg1.251,00€SRT1720 hydrochloride
CAS:SRT1720 hydrochloride (SRT1720 HCl) is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2/SIRT3 (EC1.5s: 37 μM/300 μM).Formula:C25H24ClN7OSPurezza:98% - 99.93%Colore e forma:Yellow SolidPeso molecolare:506.22Ref: TM-T2412
1mg65,00€2mg85,00€5mg132,00€1mL*10mM (DMSO)210,00€10mg236,00€25mg374,00€50mg532,00€100mg758,00€200mg1.044,00€500mg1.549,00€Selisistat
CAS:Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50=38 nM).Formula:C13H13ClN2OPurezza:98.53% - 99.94%Colore e forma:SolidPeso molecolare:248.71Ref: TM-T6111
5mg48,00€1mL*10mM (DMSO)50,00€10mg54,00€25mg87,00€50mg133,00€100mg222,00€200mg330,00€500mg535,00€AK-1
CAS:AK-1: SIRT2 inhibitor, IC50 12.5 μM, hinders Alzheimer's neurodegeneration, arrests colon cancer cell cycle.Formula:C19H21N3O5SPurezza:98.32% - 99.44%Colore e forma:SolidPeso molecolare:403.45Tenovin-6
CAS:Tenovin-6 is a p53 transcriptional activity agonist.Formula:C25H34N4O2SPurezza:98.89% - >99.99%Colore e forma:SolidPeso molecolare:454.63Ref: TM-T1818
1mg40,00€2mg52,00€5mg73,00€1mL*10mM (DMSO)74,00€10mg93,00€25mg148,00€50mg219,00€100mg371,00€500mg882,00€UBCS039
CAS:UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)Formula:C16H13N3Purezza:98.31%Colore e forma:SolidPeso molecolare:247.29Ref: TM-T7679
1mg38,00€5mg77,00€1mL*10mM (DMSO)95,00€10mg110,00€25mg215,00€50mg306,00€100mg429,00€200mg600,00€Gardenia yellow
CAS:Gardenia yellow (Crocin I) has anti atherosclerosis and hypolipidemic effects.Formula:C44H64O24Purezza:98.24% - 98.82%Colore e forma:Orange Yellow To Reddish Yellow PowderPeso molecolare:976.96
