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Sirtuina

Sirtuina

Le sirtuine sono una famiglia di deacetilasi dipendenti dal NAD+ che svolgono un ruolo cruciale nella regolazione di processi cellulari come la riparazione del DNA, l'invecchiamento, il metabolismo e la resistenza allo stress. Le sirtuine influenzano la riparazione del DNA deacetilando le proteine coinvolte nelle vie di riparazione, modulandone così l'attività. Gli inibitori e gli attivatori delle sirtuine sono strumenti preziosi nella ricerca sull'invecchiamento, il cancro e le malattie metaboliche, dove la regolazione della riparazione del DNA e della longevità cellulare è di interesse. Presso CymitQuimica, offriamo una gamma di modulatori di sirtuine di alta qualità per supportare la tua ricerca sulla riparazione del DNA, l'invecchiamento cellulare e la regolazione metabolica.

Trovati 88 prodotti di "Sirtuina"

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  • SRT 1460
    Targetmol
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    SRT 1460

    CAS:
    <p>SRT 1460 is a SIRT1 activator.</p>
    Formula:C26H29N5O4S
    Purezza:98.25%
    Colore e forma:Solid
    Peso molecolare:507.6

    Ref: TM-T8346

  • Cambinol
    Targetmol
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    Cambinol

    CAS:
    Cambinol is a SIRT1/2 inhibitor (IC50: 56/59 μM), non-competitive with NAD, weak on SIRT5, and prompts apoptosis in lymphoma cells.
    Formula:C21H16N2O2S
    Purezza:98.02% - 99.83%
    Colore e forma:Solid
    Peso molecolare:360.43

    Ref: TM-T4019

  • Sirtinol
    Targetmol
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    Sirtinol

    CAS:
    Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).
    Formula:C26H22N2O2
    Purezza:97.12% - 99.96%
    Colore e forma:Solid
    Peso molecolare:394.47

    Ref: TM-T6671

  • B2
    Targetmol
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    B2

    CAS:
    B2 (Linazolamide intermediate B impurity 2) promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease
    Formula:C20H17ClN4O3
    Purezza:99.66%
    Colore e forma:Solid
    Peso molecolare:396.83

    Ref: TM-T22595

  • MDL-800
    Targetmol
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    MDL-800

    CAS:
    MDL-800 is a SIRT6 modulator with antitumor activity for the study of hepatocellular carcinoma and non-small cell lung cancer.
    Formula:C21H16BrCl2FN2O6S2
    Purezza:99.95% - 99.96%
    Colore e forma:Solid
    Peso molecolare:626.3

    Ref: TM-T64529

  • SIRT5 inhibitor 5
    Targetmol
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    SIRT5 inhibitor 5

    CAS:
    SIRT5 inhibitor 5 is a selective and substrate-competitive SIRT5 inhibitor, which does not occupy the NAD+ binding pocket,cancer and metabolism-related disease.
    Formula:C21H14ClN3O3S
    Purezza:99.33%
    Colore e forma:Solid
    Peso molecolare:423.87

    Ref: TM-T72637

  • SIRT5 inhibitor 2
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    SIRT5 inhibitor 2

    CAS:
    SIRT5 inhibitor 2 (compound 49) has inhibitory activity through SIRT5-dependent deacetylation and cancer and neurodegenerative diseases.
    Formula:C18H12Cl2N2O3S
    Purezza:99.38% - 99.87%
    Colore e forma:Solid
    Peso molecolare:407.27

    Ref: TM-T62032

  • SIRT2-IN-9
    Targetmol
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    SIRT2-IN-9

    CAS:
    SIRT2-IN-9: selective SIRT2 inhibitor; IC50=1.3μM; halts MCF-7 cell growth; for cancer study.
    Formula:C21H22N6OS2
    Purezza:97.6%
    Colore e forma:Solid
    Peso molecolare:438.57

    Ref: TM-T62515

  • SIRT5 inhibitor 6
    Targetmol
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    SIRT5 inhibitor 6

    CAS:
    SIRT5 inhibitor 6 is Sirtuin 5 inhibitor for sepsis-associated acute kidney injury (AKI) modulates protein succinylation and pro-inflammatory cytokine release.
    Formula:C21H28N6O4S
    Purezza:99.84%
    Colore e forma:Solid
    Peso molecolare:460.55

    Ref: TM-T78802

  • Sirt2-IN-1
    Targetmol
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    Sirt2-IN-1

    CAS:
    Sirt2-IN-1 is an inhibitor of sirtuin 2 (IC50 = 163 nM).
    Formula:C28H27N7O2S2
    Purezza:99.57% - 99.84%
    Colore e forma:Solid
    Peso molecolare:557.69

    Ref: TM-T12920

  • SIRT5 inhibitor 4
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    SIRT5 inhibitor 4

    CAS:
    SIRT5 inhibitor 4 (compound 11) is a dose-dependent and selective SIRT5 (Sirtuin5) inhibitorand no inhibitory effect on SIRT1/2/3,anticancer.
    Formula:C18H15N3O4S
    Purezza:99.97%
    Colore e forma:Solid
    Peso molecolare:369.39

    Ref: TM-T61457

  • SIRT5 inhibitor 1
    Targetmol
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    SIRT5 inhibitor 1

    CAS:
    SIRT5 inhibitor 1 targets human Sirtuin 5 deacylase, with an IC50 of 0.11 μM, linked to aging diseases.
    Formula:C31H39FN6O6S2
    Purezza:97.8%
    Colore e forma:Solid
    Peso molecolare:674.81

    Ref: TM-T12921

  • SIRT6-IN-5
    Targetmol
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    SIRT6-IN-5

    CAS:
    SIRT6-IN-5: potent, selective SIRT6 inhibitor; IC50=34 μM; immunosuppressive, enhances chemo, boosts H3K9 acetylation, glucose uptake, curbs T-cell growth.
    Formula:C19H14N2O6
    Purezza:98.77%
    Colore e forma:Solid
    Peso molecolare:366.32

    Ref: TM-T24793

  • Sirtuin modulator 1
    Targetmol
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    Sirtuin modulator 1

    CAS:
    Sirtuin modulator 1 (SRT3025 Hydrochloride) is a modulator of SIRT1 with EC1.5 of < 1 μM.
    Formula:C31H32ClN5O2S2
    Purezza:99.63%
    Colore e forma:Solid
    Peso molecolare:606.2

    Ref: TM-T12922

  • WAY-354574
    Targetmol
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    WAY-354574

    CAS:
    WAY-354574 is an active compound that targets the deacetylase Sirtuin, utilized in research focused on Huntington's disease (HD) [1].
    Formula:C20H23ClN2O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:406.93

    Ref: TM-T80813

  • Sirtuin-1 inhibitor 1
    Targetmol
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    Sirtuin-1 inhibitor 1

    CAS:
    <p>Sirtuin-1 inhibitor 1 is an inhibitor against deacetylase-1 (Sirtuin-1) and can be used to study senescence and cell death in the organism.</p>
    Formula:C20H17N3O2
    Purezza:99.1%
    Colore e forma:Solid
    Peso molecolare:331.37

    Ref: TM-T79903

  • Epigenetic factor-IN-1
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    Epigenetic factor-IN-1

    CAS:
    <p>Epigenetic factor-IN-1 (40569Z) is an epigenetic factor inhibitor that exhibits potent binding affinity for SIRT7.</p>
    Formula:C32H34FN5O6S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:667.77

    Ref: TM-T82458

  • SRT3657
    Targetmol
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    SRT3657

    CAS:
    <p>SRT3657 is a brain-permeable SIRT1 activator, has neuroprotective effect.</p>
    Formula:C40H54N8O6S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:774.97

    Ref: TM-T13001

  • SIRT5 inhibitor 7
    Targetmol
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    SIRT5 inhibitor 7

    CAS:
    SIRT5 inhibitor 7 , a substrate-competitive and selective SIRT5 inhibitor, significantly attenuated renal dysfunction and pathological damage in AKI mice.
    Formula:C28H32ClN7O3S
    Purezza:99.77%
    Colore e forma:Solid
    Peso molecolare:582.12

    Ref: TM-T78803

  • SIRT-IN-1
    Targetmol
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    SIRT-IN-1

    CAS:
    <p>SIRT-IN-1 is a potent SIRT1/2/3 inhibitor(IC50s of 15, 10, 33 μM, respectively).</p>
    Formula:C19H27N5O2S
    Purezza:99.29%
    Colore e forma:Solid
    Peso molecolare:389.52

    Ref: TM-T12918