Recettore degli androgeni
Il recettore degli androgeni (AR) è un recettore ormonale nucleare che viene attivato dal legame con gli androgeni, come il testosterone e il diidrotestosterone. Questo recettore svolge un ruolo cruciale nello sviluppo e nel mantenimento delle caratteristiche maschili, nonché nella regolazione di diversi processi fisiologici, tra cui la crescita muscolare, la libido e la densità ossea. Gli inibitori del recettore degli androgeni sono ampiamente studiati nel contesto del cancro alla prostata, dove la segnalazione dell'AR è spesso sovraregolata. Presso CymitQuimica, offriamo una gamma di modulatori del recettore degli androgeni di alta qualità per supportare la tua ricerca in endocrinologia, biologia del cancro e regolazione ormonale.
Trovati 229 prodotti di "Recettore degli androgeni"
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Ralaniten triacetate
CAS:Ralaniten triacetate (EPI-506) is a precursor of Ralaniten, an AR-NTD inhibitor, which can be used in the study of prostate and breast cancer.Formula:C27H33ClO8Purezza:98.69%Colore e forma:SolidPeso molecolare:521.00Ref: TM-T36375
1mg162,00€5mg393,00€10mg655,00€25mg1.415,00€50mg1.882,00€100mg2.375,00€1mL*10mM (DMSO)449,00€ONC1-13B
CAS:ONC1-13B, an androgen receptor antagonist, is used potentially for the treatment of prostate cancer.Formula:C22H16F4N4O3SPurezza:99.36% - 99.85%Colore e forma:SolidPeso molecolare:492.45GLPG0492
CAS:GLPG0492 is a novel selective androgen receptor modulator.Formula:C19H14F3N3O3Purezza:99.58%Colore e forma:SolidPeso molecolare:389.33Ref: TM-T11410L
1mg74,00€5mg164,00€10mg235,00€25mg378,00€50mg543,00€100mg730,00€200mg938,00€1mL*10mM (DMSO)170,00€Androgen receptor antagonist 5
CAS:AR antagonist 5 blocks AR (IC50: 6.17 μM), hinders LNCaP cell growth, and has anti-tumor effects in mouse models.Formula:C21H15F4N5O3SColore e forma:SolidPeso molecolare:493.43Celiprolol hydrochloride
CAS:Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.Formula:C20H33N3O4·HClColore e forma:White Crystalline SolidPeso molecolare:415.96VPC-14228
CAS:VPC-14228 is a specific AR-DBD inhibitor that acts by inhibiting both Y594A and Q592A mutants.Formula:C13H14N2OSPurezza:99.96%Colore e forma:SolidPeso molecolare:246.33N-Nitrosodicyclohexylamine
CAS:N-Nitrosodicyclohexylamine (NDCHA), an N-nitrosocompound, exhibits anti-androgenic activity by competitively binding to the androgen receptor (AR) in oppositionFormula:C12H22N2OPurezza:98%Colore e forma:SolidPeso molecolare:210.32Androgen receptor degrader-2
CAS:Androgen Receptor Degrader-2 (Compound 9) is a potent degrader of androgen receptors, with potential application in cancer research [1].Formula:C16H16ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:349.77(rel)-BMS-641988
CAS:(rel)-BMS-641988, a relative configuration of the potent nonsteroidal androgen receptor antagonist BMS-641988, holds potential for prostate cancer research.Formula:C20H20F3N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:471.45JNJ-26146900
CAS:JNJ-26146900 is a nonsteroidal androgen receptor (AR) ligand with tissue-selective activity in rats. JNJ-26146900 binds to the rat AR with a K(i) of 400nM.Formula:C15H15F3N2O3SPurezza:98%Colore e forma:SolidPeso molecolare:360.35Trimegestone
CAS:Trimegestone, a highly effective oral progestogen, is used for endometrial protection, all doses inducing secretory endometrial transformation.Formula:C22H30O3Purezza:98%Colore e forma:SolidPeso molecolare:342.47YXG-158
CAS:YXG-158 (Compound 23-h), an orally active androgen receptor (AR) degrader and cytochrome P450 17A1 (CYP17A1) inhibitor, exhibits AR degradation with a DC50 of 1Formula:C30H36FN3OPurezza:98%Colore e forma:SolidPeso molecolare:473.62Androgen receptor degrader-3
CAS:Androgen Receptor Degrader-3 (ARD-3) is a compound that inhibits androgen receptor signaling and promotes the degradation of the receptor, with potentialFormula:C45H51ClN8O5Purezza:98%Colore e forma:SolidPeso molecolare:819.39PLK1/BRD4-IN-1
CAS:PLK1/BRD4-IN-1 (9b) is an orally active dual inhibitor of PLK1 (IC50: 22 nM) and BRD4 (IC50: 109 nM).Formula:C31H43N9O2Colore e forma:SolidPeso molecolare:573.73Androgen receptor-IN-5
CAS:Androgen receptor-IN-5 is a potent inhibitor of the androgen receptor with anticancer properties.Formula:C22H10Cl2F4N4OSPurezza:98%Colore e forma:SolidPeso molecolare:525.31Androgen receptor degrader-1
CAS:Androgen Receptor Degrader-1 (Compound 18) is a potent agent for androgen receptor degradation, applicable in cancer research [1].Formula:C15H14ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:335.74JJH260
CAS:JJH260, a N-hydroxy hydantoin carbamate, inhibits AIG1 and ADTRP with IC50 values of 0.57 μM and 8.5 μM, respectively, and targets ABHD6, LYPLA1/2.Formula:C29H34ClN5O5Colore e forma:SolidPeso molecolare:568.06EPI-7170
CAS:EPI-7170: Ralaniten analogue, blocks androgen receptor, inhibits transcription in AR & variants, fights enzalutamide-resistant prostate cancer.Formula:C22H28Cl3NO6SColore e forma:SolidPeso molecolare:540.88LGD-2941
CAS:LGD-2941 is an androgen receptor modulator. LGD-2941 is used for the treatment of hypogonadism, female sexual dysfunction and menopausal syndrome.Formula:C17H16F6N2O2Colore e forma:SolidPeso molecolare:394.31RU 59063
CAS:RU 59063 is a prototype of a new class of high-affinity nonsteroidal androgen receptor (AR) ligands.Formula:C17H18F3N3O2SPurezza:99.09%Colore e forma:SolidPeso molecolare:385.4Ref: TM-T20761
1mg87,00€5mg192,00€10mg284,00€25mg452,00€50mg645,00€100mg867,00€200mg1.130,00€1mL*10mM (DMSO)208,00€
