Immunologia e infiammazione
Gli inibitori dell'immunologia e dell'infiammazione sono composti che modulano la risposta immunitaria e i processi infiammatori. Questi inibitori sono fondamentali per studiare i meccanismi della regolazione immunitaria, dell'autoimmunità e dell'infiammazione cronica, nonché per sviluppare trattamenti per malattie infiammatorie, allergie e disturbi correlati al sistema immunitario. Mirando a percorsi chiave nel sistema immunitario, questi inibitori possono aiutare a ridurre risposte immunitarie eccessive o inappropriate. Presso CymitQuimica, offriamo un'ampia selezione di inibitori di alta qualità per supportare le tue ricerche in immunologia, infiammazione e sviluppo terapeutico.
Sottocategorie di "Immunologia e infiammazione"
- CCR(140 prodotti)
- CXCR(159 prodotti)
- Parete cellulare(5 prodotti)
- Ricettore IL(110 prodotti)
- IκB/IKK(58 prodotti)
- LTR(3 prodotti)
- MALT(25 prodotti)
- MRP(6 prodotti)
- NADPH-ossidasi(1 prodotti)
- NF-κB(415 prodotti)
- NOD(23 prodotti)
- NOS(61 prodotti)
- Nrf2(82 prodotti)
- Sintasi PGE(31 prodotti)
- ROS(70 prodotti)
- TGF-beta/Smad(63 prodotti)
- TLR(73 prodotti)
- Tioredossina(12 prodotti)
- gp120/CD4(4 prodotti)
Mostrare 11 più sottocategorie
Trovati 3385 prodotti di "Immunologia e infiammazione"
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Heme Oxygenase-1-IN-2
Heme Oxygenase-1-IN-2 is a novel inhibitor of heme oxygenase-1 (HO-1), displaying potent antiproliferative activity in vitro, with an IC50 value of 0.95 μM.Formula:C19H18ClN3OColore e forma:SolidPeso molecolare:339.82YE6144
CAS:YE6144, IRF5 phosphorylation blocker. Affordable Excellence: Reliable Quality You Can TrustFormula:C21H27ClFN7OColore e forma:SolidPeso molecolare:447.94ODN 2088
CAS:ODN 2088 is a potent inhibitor of TLR3, TLR7 and TLR9 that is non-cytotoxic and shows inhibition of the release of IFN-α and IL-6.Colore e forma:SolidCorannulene
CAS:Corannulene is an agonist of the aromatic hydrocarbon receptor (AhR). It induces a lower cytotoxic response in liver cancer cells compared to Benzo[a]pyrene and shows potential for use in cancer research.
Formula:C20H10Colore e forma:SolidPeso molecolare:250.293MAY0132
CAS:MAY0132 is a potent and selective EPAC2 inhibitor with an IC50 of 0.4 μM. It significantly inhibits the replication of HMPV, AdV, and RSV, reduces cytokine/chemokine production induced by viral infections, and suppresses NF-κB activation. MAY0132 exhibits antiviral activity and can be used in respiratory virus infection research.Formula:C16H15ClF3NColore e forma:SolidPeso molecolare:313.7452-Guanidinobezimidazole
CAS:2-Guanidinobenzimidazole (2GBI) is a selective agonist of NLRP3, with a KD value of 1.29 μM for His-GFP-NLRP3. It directly binds to the LRR domain of NLRP3, facilitating the assembly and activation of the inflammasome. Additionally, 2-Guanidinobenzimidazole enhances antitumor immunity, inhibits tumor growth, and overcomes resistance to immune checkpoint blockade (ICB).
Formula:C8H9N5Colore e forma:SolidPeso molecolare:175.191AMS-17
AMS-17, a strong NLRP3 inhibitor, quells microglia activation and cytokines like caspase-1, TNF-α, IL-1β, iNOS in studies.Formula:C15H13F3N4O3SColore e forma:SolidPeso molecolare:386.35COX-2-IN-8
COX-2-IN-8 (Compound 6a) is a potent, selective, orally active COX-2 inhibitor (IC50: 6.585 μM) with a higher COX-2 selectivity than Celecoxib.Formula:C19H19N3O4S2Colore e forma:SolidPeso molecolare:417.5SP11
CAS:SP11 is a mitochondrial reactive oxygen species (ROS) inhibitor. It activates Fis1 with an IC50 of 9.4 µM by binding to Cys41 and enhances the translocation of Drp1 to mitochondria. SP11 is utilized for research into oxidative stress damage.Formula:C18H19ClN2OSColore e forma:SolidPeso molecolare:346.87DBMB
CAS:DBMB is a spleen tyrosine kinase (Syk) inhibitor that significantly suppresses Syk enzyme activity. It possesses anti-inflammatory properties by inhibiting NF-κB signaling, thereby reducing the production of inflammatory mediators such as nitric oxide (NO) and prostaglandin E2 (PGE2). DBMB can be utilized in research on inflammatory diseases.Formula:C24H22N4OColore e forma:SolidPeso molecolare:382.458AhR agonist 2
AhR agonist 2 is aryl hydrocarbon receptor (AhR) agonist,oral, inducing rapid nuclear enrichment of the AhR and facilitating skin barrier repair,psoriasis.Formula:C12H7Br2N3Colore e forma:SolidPeso molecolare:353.01ND-2158
CAS:ND-2158 is a potent and selective inhibitor of IRAK4.Formula:C22H30N4O4SPurezza:98%Colore e forma:SolidPeso molecolare:446.56nNOS-IN-5
CAS:nNOS-IN-5 (Compound 9) is a potent inhibitor of human neuronal nitric oxide synthase (nNOS) with a Ki of 22 nM. It exhibits remarkable selectivity, being 900 times more selective for human nNOS over endothelial nitric oxide synthase (eNOS). nNOS-IN-5 is applicable in research related to neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.Formula:C23H22N4OColore e forma:SolidPeso molecolare:370.447NOD1/2 antagonist-1
CAS:NOD1/2 antagonist-1 inhibits NOD1 (IC50 1.13 μM) and NOD2 (IC50 0.77 μM), enhances paclitaxel antitumor efficacy and is used to study innate immune signaling.Formula:C32H28ClF5N4O4Purezza:99.69%Colore e forma:SolidPeso molecolare:663.03CDA-IN-3
CAS:CDA-IN-3 (NCDI) is a chitin deacetylase (CDA) inhibitor with antiparasitic properties. It disrupts chitin metabolism in nematodes, increasing ROS levels within these organisms and causing cellular damage. CDA-IN-3 significantly inhibits all developmental stages of Caenorhabditis elegans and can be utilized in research focused on anti-infective applications.Formula:C16H27N3O3S2Colore e forma:SolidPeso molecolare:373.534ARG1-IN-1
CAS:ARG1-IN-1 is a human arginase 1 inhibitor with an IC 50 of 29 nM.Formula:C11H21BN2O4Colore e forma:SolidPeso molecolare:256.11NLRP3/AIM2-IN-1
NLRP3/AIM2-IN-1 is an inhibitor of thermal sepsis (IC50 = 3.136 ± 0.7667 μM).Formula:C15H16BNO4Colore e forma:SolidPeso molecolare:285.1Galectin-3-IN-6
CAS:Galectin-3-IN-6 (Compound 12) is an orally active galectin-3 (Gal-3) inhibitor, with an IC50 of 12 nM and a Kd of 13 nM for Gal-3. In a CCl4-induced mouse model of acute liver injury and fibrosis, Galectin-3-IN-6 significantly reduces fibrosis markers collagen-1 and α-smooth muscle actin (αSMA) by 64% and 71%, respectively, demonstrating notable anti-fibrotic activity. Galectin-3-IN-6 is applicable for research in fibrosis-related diseases, cancer, and cardiovascular disorders.Formula:C28H29Cl2F3N4O6Colore e forma:SolidPeso molecolare:645.454SDH-IN-25
CAS:SDH-IN-25 is an SDH inhibitor with an IC50 of 4.82 mg/L, demonstrating broad-spectrum and potent antifungal activity. By binding to SDH amino acid residues (TRP173, TYR58, and ARG43), it mimics the action mode of the commercial fungicide flutolanil. SDH-IN-25 induces changes in hyphal morphology, disrupts respiratory metabolism by binding to complex II, generates reactive oxygen species (ROS), and affects mitochondrial membrane potential (MMP) in hyphae. This compound is utilized in agricultural disease control research.
Formula:C19H15BrCl2N2O4Colore e forma:SolidPeso molecolare:486.143NOS-IN-2
NOS-IN-2: potent, selective imidamide NOS inhibitor, IC50=20μM for iNOS, spares eNOS, low toxicity, useful in inflammation research.Formula:C18H20F3N3O2Colore e forma:SolidPeso molecolare:367.37
