Immunologia e infiammazione
Gli inibitori dell'immunologia e dell'infiammazione sono composti che modulano la risposta immunitaria e i processi infiammatori. Questi inibitori sono fondamentali per studiare i meccanismi della regolazione immunitaria, dell'autoimmunità e dell'infiammazione cronica, nonché per sviluppare trattamenti per malattie infiammatorie, allergie e disturbi correlati al sistema immunitario. Mirando a percorsi chiave nel sistema immunitario, questi inibitori possono aiutare a ridurre risposte immunitarie eccessive o inappropriate. Presso CymitQuimica, offriamo un'ampia selezione di inibitori di alta qualità per supportare le tue ricerche in immunologia, infiammazione e sviluppo terapeutico.
Sottocategorie di "Immunologia e infiammazione"
- CCR(142 prodotti)
- CXCR(159 prodotti)
- Parete cellulare(5 prodotti)
- Ricettore IL(110 prodotti)
- IκB/IKK(58 prodotti)
- LTR(3 prodotti)
- MALT(25 prodotti)
- MRP(6 prodotti)
- NADPH-ossidasi(1 prodotti)
- NF-κB(425 prodotti)
- NOD(21 prodotti)
- NOS(61 prodotti)
- Nrf2(82 prodotti)
- Sintasi PGE(31 prodotti)
- ROS(70 prodotti)
- TGF-beta/Smad(63 prodotti)
- TLR(73 prodotti)
- Tioredossina(12 prodotti)
- gp120/CD4(4 prodotti)
Mostrare 11 più sottocategorie
Trovati 3389 prodotti di "Immunologia e infiammazione"
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CD73-IN-13
CD73-IN-13, a potent CD73 inhibitor, may be developed for tumor-related disease treatment.Formula:C13H11F3N4O2Colore e forma:SolidPeso molecolare:312.25SARM1-IN-5
CAS:SARM1-IN-5 (compound 1-23-a) is an inhibitor of SARM1, useful for researching diseases related to axonal degeneration, including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS).Formula:C18H17FN6OColore e forma:SolidPeso molecolare:352.37Anti-inflammatory agent 102
CAS:Anti-inflammatory agent 102 (Compound 11a) is an orally effective anti-inflammatory compound. It exerts its effects by inhibiting the activation of the ASK1/p38 MAPKs/NF-κB signaling pathway. This agent displays significant anti-inflammatory activity by suppressing the release of NO, ROS, and inflammatory cytokines such as IL-6, TNF-α, and IL-1β. Anti-inflammatory agent 102 is applicable in research concerning inflammatory diseases, including ulcerative colitis (UC).Formula:C16H16ClN3O3Colore e forma:SolidPeso molecolare:333.77MALT1-IN-5
CAS:MALT1-IN-5 is a potent inhibitor of the MALT1 protease and can be used in cancer research.Formula:C17H17ClF2N6O3Colore e forma:SolidPeso molecolare:426.80Itaconic acid prodrug-1
CAS:Itaconic acid prodrug-1 (Compound P2) is an orally active prodrug of Itaconic acid that efficiently delivers Itaconic acid to skin tissues upon oral administration. It exhibits immunomodulatory effects, significantly inhibiting Poly(I:C)/IFNγ-induced inflammatory cytokines in human epidermal keratinocytes. Itaconic acid prodrug-1 is useful for research into alopecia areata and other inflammatory skin conditions.Formula:C15H22O10Colore e forma:SolidPeso molecolare:362.329KBD4466
CAS:KBD4466 is a potent oral inhibitor of TLR7 and TLR8, with IC50 values of 0.9 nM and 2.8 nM, respectively. This compound effectively suppresses the inflammatory cytokines IL-6 and IFN-α. KBD4466 has shown to improve disease progression and increase survival rates in the BXSB/MpJ mouse model of systemic lupus erythematosus (SLE). It is suitable for research into autoimmune diseases.Formula:C24H23F3N6OColore e forma:SolidPeso molecolare:468.47(Rel)-Factor B-IN-5
CAS:(Rel)-Factor B-IN-5 is a complement factor B inhibitor that can be used to study diseases associated with activation of the alternative complement pathway.Formula:C27H32N2O4Purezza:>99.99%Colore e forma:SolidPeso molecolare:448.55Anti-inflammatory agent 18
Anti-inflammatory agent 18: NO activity blocker (IC50: 15.94 μM), hampers HMGB1-induced inflammation, potential for COVID-19, sepsis study.Formula:C30H50O6Colore e forma:SolidPeso molecolare:506.71NLRP3-IN-70
CAS:NLRP3-IN-70 (Compound 5m) is an inhibitor of the NLRP3 inflammasome with low oral bioavailability. It binds directly to the NACHT domain of the NLRP3 protein, thereby blocking its interaction with ASC, which inhibits ASC oligomerization and the assembly of the NLRP3 inflammasome. NLRP3-IN-70 is applicable in studies on sepsis and non-alcoholic steatohepatitis.
Formula:C23H23NO5Colore e forma:SolidPeso molecolare:393.432Galectin-8-IN-1
Galectin-8-IN-1 selectively binds galectin-8N with 48 μM affinity, 15x more than galectin-3.Formula:C16H18N2O6Colore e forma:SolidPeso molecolare:334.32Cbl-b-IN-1
CAS:Cbl-b-IN-1 is a potent Cbl-b inhibitor (IC50 <100 nM) with potential anticancer activity for the study of intestinal inflammation.Formula:C29H34N6O2Purezza:99.68%Colore e forma:SolidPeso molecolare:498.631trans-3-(3-Pyridyl)acrylic acid
CAS:Trans-3-(3-Pyridyl)acrylic acid (compound 15) is a trans-3-aryl acrylic acid demonstrating antiviral activity against tobacco mosaic virus (TMV) [1].Formula:C8H7NO2Colore e forma:SolidPeso molecolare:149.15IRAK4-IN-30
CAS:IRAK4-IN-30 (Compound I) is an inhibitor of IRAK4, with an IC50 of 0.6 nM.
Formula:C27H33N5O5Colore e forma:SolidPeso molecolare:507.581COX-2-IN-12
COX-2-IN-12: Potent, selective COX-2 inhibitor, IC50=19.98μM, safe anti-inflammatory with low acute toxicity.Formula:C17H19NO3Colore e forma:SolidPeso molecolare:285.34(S)-MALT1-IN-5
CAS:(S)-MALT1-IN-5: Potent MALT1 protease inhibitor, may help in abnormal T/B-cell signalling and MALT1-linked diseases.Formula:C17H17ClF2N6O3Colore e forma:SolidPeso molecolare:426.80UM-3006
CAS:UM-3006 is a potent TLR7/8 agonist that enhances immune responses by activating the TLR signaling pathway. This compound holds significant research and application potential in the fields of vaccine adjuvants and immune diseases.Formula:C20H34N6O2Colore e forma:SolidPeso molecolare:390.52STING-IN-11
CAS:STING-IN-11 is a potent, orally bioavailable STING inhibitor (IC₅₀ = 37.8 nM) that blocks STING protein palmitoylation and downstream signaling.Formula:C21H20ClF2N3OPurezza:99.84%Colore e forma:SolidPeso molecolare:403.85LD03-DEX
CAS:LD03-DEX is a precursor compound of dexamethasone, characterized by its immunosuppressive activity.Formula:C44H65FO8Colore e forma:SolidPeso molecolare:740.98HG-12-6
CAS:HG-12-6 is a type II IRAK4 inhibitor, targeting its inactive form with an IC50 of 165 nM, and is used in autoimmunity and inflammation.Formula:C29H27F3N6O2SPurezza:98%Colore e forma:SolidPeso molecolare:580.62Amilo-5MER
CAS:Amilo-5MER (5-MP) is an orally active and selective inhibitor of serum amyloid A (SAA). It specifically suppresses the release of pro-inflammatory cytokines IL-6 and IL-1β in SAA-activated cells. Amilo-5MER reduces chronic inflammation and alleviates symptoms of diseases such as rheumatoid arthritis (RA), inflammatory bowel disease (IBD), and multiple sclerosis (MS). It holds potential for research in autoimmune and chronic inflammatory diseases.Formula:C23H40N6O9SColore e forma:SolidPeso molecolare:576.664
