
NF-κB
Il fattore nucleare kappa-light-chain-enhancer delle cellule B attivate (NF-κB) è un fattore di trascrizione che regola l'espressione di geni coinvolti nelle risposte immunitarie, nell'infiammazione, nella sopravvivenza cellulare e nella proliferazione. NF-κB viene attivato in risposta a vari stimoli, tra cui citochine, agenti patogeni e segnali di stress. La disregolazione della segnalazione di NF-κB è associata a malattie infiammatorie croniche, cancro e disturbi autoimmuni. Presso CymitQuimica, offriamo una selezione completa di modulatori della via NF-κB per supportare la tua ricerca su infiammazione, oncologia e regolazione immunitaria.
Trovati 407 prodotti di "NF-κB"
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Sauchinone
CAS:Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.Formula:C20H20O6Purezza:99.12% - >99.99%Colore e forma:SolidPeso molecolare:356.37Maslinic acid
CAS:Maslinic acid (Crategolic acid) is a DNA polymerase B inhibitor.Formula:C30H48O4Purezza:98.1% - 99.98%Colore e forma:SolidPeso molecolare:472.70Sanggenon C
CAS:Sanggenon C inhibits NF-κB activity, the expression of inducible nitric oxide synthase, tumor necrosis factor-α-stimulated cell adhesion and the expression of vascular cell adhesion molecule-1 in RAW264.7 cells. Cost-effective and quality-assured.Formula:C40H36O12Purezza:97.76% - 99.76%Colore e forma:SolidPeso molecolare:708.71Ref: TM-T4S1615
1mg93,00€5mg188,00€10mg283,00€25mg494,00€50mg702,00€100mg938,00€200mg1.301,00€1mL*10mM (DMSO)284,00€RIPA-56
CAS:RIPA-56 is an inhibitor of RIP1Formula:C13H19NO2Purezza:99.53% - 99.93%Colore e forma:SolidPeso molecolare:221.3Ref: TM-T7795
5mg38,00€10mg52,00€25mg94,00€50mg136,00€100mg213,00€200mg316,00€500mg532,00€1mL*10mM (DMSO)55,00€HOMOPLANTAGININ
CAS:Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and showsFormula:C22H22O11Purezza:97.63% - 99.66%Colore e forma:SolidPeso molecolare:462.40SC75741
CAS:SC75741 is a potent P65 inhibitor with IC50 of 200 nMFormula:C29H23N7O2S2Purezza:99.44% - 99.54%Colore e forma:SolidPeso molecolare:565.67Ref: TM-T6661
1mg40,00€5mg73,00€10mg105,00€25mg177,00€50mg281,00€100mg432,00€200mg618,00€1mL*10mM (DMSO)93,00€Sulforaphene
CAS:Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.Formula:C6H9NOS2Purezza:97.55% - 99.67%Colore e forma:Slightly Yellowish LiquidPeso molecolare:175.27Ref: TM-TL0016
1mg34,00€2mg46,00€5mg66,00€10mg92,00€25mg167,00€50mg241,00€100mg359,00€200mg525,00€1mL*10mM (DMSO)65,00€Ginsenoside Rg5
CAS:Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.Formula:C42H70O12Purezza:98% - 99.65%Colore e forma:SolidPeso molecolare:767.00Ref: TM-T6S1487
1mg107,00€5mg251,00€10mg404,00€25mg665,00€50mg888,00€100mg1.251,00€1mL*10mM (DMSO)341,00€WAY-169916
CAS:WAY-169916 inhibits ER by blocking NF-kB activity, lacks estrogenic effects.Formula:C17H13F3N2O2Purezza:98.63% - 98.64%Colore e forma:SolidPeso molecolare:334.29Ref: TM-T8981
2mg39,00€5mg60,00€10mg92,00€25mg187,00€50mg313,00€100mg450,00€200mg620,00€1mL*10mM (DMSO)89,00€1-Caffeoylquinic acid
CAS:1-Caffeoylquinic acid: a lignin precursor with anti-influenza, antioxidant properties, and moderates post-meal glucose release.Formula:C16H18O9Purezza:99.15% - 99.16%Colore e forma:SolidPeso molecolare:354.31Ref: TM-TN1051
1mg71,00€5mg160,00€10mg250,00€25mg425,00€50mgPrezzo su richiesta1mL*10mM (DMSO)167,00€Astilbin
CAS:Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.Formula:C21H22O11Purezza:97% - 99.86%Colore e forma:White PowderPeso molecolare:450.39Ref: TM-T2794
5mg49,00€10mg73,00€25mg133,00€50mg212,00€100mg316,00€200mg452,00€500mg737,00€1mL*10mM (DMSO)49,00€Praeruptorin A
CAS:Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulinFormula:C21H22O7Purezza:99.63% - 99.65%Colore e forma:SolidPeso molecolare:386.4Tenuigenin
CAS:Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.Formula:C30H45ClO6Purezza:98.9% - 99.53%Colore e forma:SolidPeso molecolare:537.13Ref: TM-T3907
2mg34,00€5mg50,00€10mg73,00€25mg105,00€50mg152,00€100mg215,00€200mg318,00€1mL*10mM (DMSO)63,00€Tectochrysin
CAS:Tectochrysin: antioxidant, hinders ABCG2 transport, induces apoptosis in NSC-LC by blocking STAT3 and activating DR3/Fas.Formula:C16H12O4Purezza:99.26%Colore e forma:SolidPeso molecolare:268.26INH14
CAS:INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).Formula:C15H16N2OPurezza:95.41%Colore e forma:SolidPeso molecolare:240.311-Keto-β-boswellic acid
CAS:11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.Formula:C30H46O4Purezza:99.68%Colore e forma:SolidPeso molecolare:470.68Ref: TM-TN1182
1mg60,00€5mg137,00€10mg210,00€25mg356,00€50mg525,00€100mg750,00€1mL*10mM (DMSO)140,00€Picroside II
CAS:Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.Formula:C23H28O13Purezza:98% - 99.83%Colore e forma:SolidPeso molecolare:512.46Phorbol 12-myristate 13-acetate
CAS:Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.Formula:C36H56O8Purezza:98.55% - >99.99%Colore e forma:White To Off-White SolidPeso molecolare:616.83Tomatidine
CAS:Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.
Formula:C27H45NO2Purezza:99.94% - 99.98%Colore e forma:SolidPeso molecolare:415.65IRAK-1-4 Inhibitor I
CAS:IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1.
Formula:C20H21N5O4Purezza:98% - 99.89%Colore e forma:SolidPeso molecolare:395.41
