NF-κB
Il fattore nucleare kappa-light-chain-enhancer delle cellule B attivate (NF-κB) è un fattore di trascrizione che regola l'espressione di geni coinvolti nelle risposte immunitarie, nell'infiammazione, nella sopravvivenza cellulare e nella proliferazione. NF-κB viene attivato in risposta a vari stimoli, tra cui citochine, agenti patogeni e segnali di stress. La disregolazione della segnalazione di NF-κB è associata a malattie infiammatorie croniche, cancro e disturbi autoimmuni. Presso CymitQuimica, offriamo una selezione completa di modulatori della via NF-κB per supportare la tua ricerca su infiammazione, oncologia e regolazione immunitaria.
Trovati 365 prodotti per "NF-κB".
Filtra per
Percentuale di purezza
0
100
|
0
|
50
|
90
|
95
|
100
- Prezzo più basso
- Prezzo più alto
- Purezza più bassa
- Purezza più alta
- Consegna più veloce
Asperbisabolane L
Asperbisabolane L, a sesquiterpenoid, combats inflammation by blocking NF-κB signaling and NO in BV-2 cells.Formula:C12H14O3Colore e forma:SolidPeso molecolare:206.24XT2
CAS:XT2 is a potent, oral NF-κB-inducing kinase (NIK) inhibitor with an IC50 of 9.1 nM, reduces ALT levels, and curbs immune cell liver infiltration.Formula:C19H14FN5OSColore e forma:SolidPeso molecolare:379.411DMX-129
CAS:DMX-129 is a chemical compound acting as an inhibitor for both ΙΚΚε and TBK-1, demonstrating efficacy with IC50 values of below 30 nM for each [1].Formula:C19H17FN8Colore e forma:SolidPeso molecolare:376.39TNF-α-IN-18
CAS:TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.Formula:C16H7ClF2O4Purezza:99.77%Colore e forma:SolidPeso molecolare:336.67Anti-inflammatory agent 21
CAS:Compound 9o: orally active, low-toxicity anti-inflammatory; inhibits NO (IC50: 0.76 μM), blocks NF-κB/MAPK, reduces arthritis symptoms.Formula:C24H21FO6Colore e forma:SolidPeso molecolare:424.42Sul-121 HCl
CAS:Sul-121 HCl combats COPD by reducing inflammation and AHR via oxidative stress inhibition.Formula:C18H27ClN2O3Purezza:98%Colore e forma:SolidPeso molecolare:354.872HSR1304
CAS:HSR1304 (5d) inhibits NFκB, key in diseases like cancer, offering research potential.Formula:C24H21ClN2O3Colore e forma:SolidPeso molecolare:420.89Metaxalone-D6
CAS:Metaxalone-d6: internal standard for GC/LC-MS quantification; muscle relaxant; inhibits cell proliferation; reduces inflammation. Used for back pain.Formula:C12H15NO3Peso molecolare:227.2894Bezisterim
CAS:Bezisterim （HE3286） can bind ERK and reduce inflammation-driven ERK/NF-κB signaling; it has blood-brain barrier permeability and anti-neuroinflammatory effects in rodent models, and is mainly metabolized by CYP3A4.Formula:C21H30O3Purezza:99.73%Colore e forma:SolidPeso molecolare:330.46Bay 65-1942 free base
CAS:Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.Formula:C22H25N3O4Purezza:98%Colore e forma:SolidPeso molecolare:395.45CID-2858522
CAS:CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).Formula:C28H39N3O3Purezza:96.12%Colore e forma:White SolidPeso molecolare:465.6276NF-κB-IN-3
CAS:NF-κB-IN-3 (Compound 2) is an NF-κB inhibitor (IC50: 0.70 μM) and can be used as an anti-tumour agent.Formula:C24H18ClF3N2O2Colore e forma:SolidPeso molecolare:458.86BAY32-5915
CAS:BAY32-5915 is a selective inhibitor of IKKalpha.Formula:C10H7NO3Purezza:96.48% - 97.51%Colore e forma:SolidPeso molecolare:189.1675IT-901
CAS:IT-901: Oral NF-κB c-Rel inhibitor, IC50 0.1 µM. Blocks c-Rel/DNA binding, IC50 3 µM. Antitumor naphthalene derivative for lymphoma/myeloma therapy.Formula:C17H14N2O4SPurezza:98.06%Colore e forma:Red SolidPeso molecolare:342.37Edasalonexent
CAS:Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy.Formula:C31H42N2O3Purezza:99.13% - >99.99%Colore e forma:SolidPeso molecolare:490.6768Bay 65-1942 hydrochloride
CAS:Bay 65-1942 hydrochloride is an inhibitor of ATP-competitive and selective IKKβ.Formula:C22H26ClN3O4Colore e forma:SolidPeso molecolare:431.913IKKβ-IN-1
CAS:IKKβ-IN-1 is a potent, orally active inhibitor of IkappaB (IKK-β) (IC50: 0.20 μM).Formula:C31H30N4O4SColore e forma:SolidPeso molecolare:554.66Gue1654
CAS:Gue1654 is an OXE-R inhibitor and cardiomyocyte apoptosis.Gue1654 can be used for the study of cardiovascular diseases.Formula:C23H17N3OS3Purezza:98.04% - 99.7%Colore e forma:SolidPeso molecolare:447.596GSK319347A
CAS:GSK319347A is a dual inhibitor of TBK1 and IKKε that inhibits IKK2 and can be used to study bladder and lung adenocarcinomas.Formula:C22H19N3O5S2Purezza:98.42%Colore e forma:SolidPeso molecolare:469.533TBK1/IKKε-IN-4
CAS:TBK1/IKKε-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKε, demonstrating IC50 values of 13 nM and 59 nMFormula:C28H35N7O4Colore e forma:SolidPeso molecolare:533.622
