CCR
I recettori delle chemochine C-C (CCR) sono un gruppo di GPCR che rispondono alle chemochine, molecole segnalatrici che guidano la migrazione delle cellule immunitarie verso i siti di infiammazione o infezione. I CCR svolgono ruoli cruciali nelle risposte immunitarie, nell'infiammazione e nello sviluppo di varie malattie, tra cui disturbi autoimmuni e cancro. La modulazione dell'attività dei CCR è esplorata come strategia terapeutica per condizioni come l'artrite reumatoide, la sclerosi multipla e l'infezione da HIV. Presso CymitQuimica, offriamo una gamma di modulatori CCR di alta qualità per supportare la tua ricerca in immunologia, infiammazione e sviluppo terapeutico.
Trovati 135 prodotti di "CCR"
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Vercirnon
CAS:Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.Formula:C22H21ClN2O4SPurezza:99.23%Colore e forma:SolidPeso molecolare:444.93Ref: TM-T17225
1mg105,00€5mg259,00€10mg406,00€25mg680,00€50mg938,00€100mg1.301,00€500mg2.593,00€1mL*10mM (DMSO)363,00€BMS-813160
CAS:BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.Formula:C25H40N8O2Purezza:99.66% - 99.79%Colore e forma:SolidPeso molecolare:484.64Ref: TM-T4584
1mg63,00€5mg137,00€10mg187,00€25mg341,00€50mg567,00€100mg810,00€500mg1.644,00€1mL*10mM (DMSO)145,00€AZD-4818
CAS:AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.Formula:C27H32Cl2N2O7Purezza:99.01%Colore e forma:SolidPeso molecolare:567.46Cenicriviroc
CAS:Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.Formula:C41H52N4O4SPurezza:97.87%Colore e forma:SolidPeso molecolare:696.94Ref: TM-TQ0297
1mg63,00€2mg90,00€5mg133,00€10mg212,00€25mg423,00€50mg550,00€100mg715,00€200mg964,00€1mL*10mM (DMSO)200,00€R243
CAS:R243 is CCR8 signaling and chemotaxis inhibitor.Formula:C21H27NO4Purezza:99.03%Colore e forma:SolidPeso molecolare:357.44Ref: TM-T24700
1mg40,00€2mg52,00€5mg80,00€10mg117,00€25mg207,00€50mg333,00€100mg495,00€1mL*10mM (DMSO)90,00€Vercirnon sodium
CAS:Vercirnon (GSK1605786A) sodium: oral CCR9 antagonist, inhibits Ca2+ mobilization/chemotaxis, IC50 = 2.6-5.4 nM, selective for CCR9 vs. CCR1-12/CX3CR1-7.Formula:C22H21ClN2NaO4SColore e forma:SolidPeso molecolare:467.92RS 504393
CAS:RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).Formula:C25H27N3O3Purezza:98.64% - 99.62%Colore e forma:SolidPeso molecolare:417.5Vicriviroc maleate
CAS:Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus.
Formula:C32H42F3N5O6Purezza:98.16% - 98.37%Colore e forma:SolidPeso molecolare:649.7Bindarit
CAS:Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Cost-effective and quality-assured.Formula:C19H20N2O3Purezza:98.35% - 98.55%Colore e forma:SolidPeso molecolare:324.37Ref: TM-T6413
1mg35,00€2mg50,00€5mg75,00€10mg110,00€25mg178,00€50mg314,00€100mg492,00€200mg710,00€1mL*10mM (DMSO)84,00€AZD2098
CAS:AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.Formula:C11H9Cl2N3O3SPurezza:99.80% - >99.99%Colore e forma:SolidPeso molecolare:334.18Ref: TM-T4300
1mg34,00€5mg66,00€10mg105,00€25mg217,00€50mg334,00€100mg502,00€500mg1.063,00€1mL*10mM (DMSO)73,00€TAK-779
CAS:TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).Formula:C33H39ClN2O2Purezza:99.21%Colore e forma:SolidPeso molecolare:531.13RE-640
CAS:NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.Formula:C20H16Cl2N4Purezza:99.60% - 99.87%Colore e forma:SolidPeso molecolare:383.27RS102895
CAS:RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.Formula:C21H21F3N2O2Purezza:97.64% - 99.80%Colore e forma:SolidPeso molecolare:390.47,4'-Dihydroxyflavone
CAS:7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.Formula:C15H10O4Purezza:99.39% - 99.6%Colore e forma:SolidPeso molecolare:254.24Vicriviroc
CAS:Vicriviroc, also known as MK4176 is a CCR5 antagonist.Formula:C28H38F3N5O2Colore e forma:SolidPeso molecolare:533.63CCR2 antagonist 4 hydrochloride
CAS:CCR2 antagonist 4 hydrochloride is a specific CCR2 antagonist (IC50s: 180 nM for CCR2b). It potently inhibits MCP-1-induced chemotaxis (IC50: 24 nM).Formula:C21H22Cl2F3N3O2Colore e forma:SolidPeso molecolare:476.32PF-4136309
CAS:PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.Formula:C29H31F3N6O3Purezza:98.85% - 99.47%Colore e forma:SolidPeso molecolare:568.59ZK 756326
CAS:ZK 756326: Selective CCR8 agonist, IC50 1.8 μM (human), 2.6 μM (mouse), no CCR4/5, CXCR3/4 action, 28-fold selectivity vs 26 GPCRs, anti-HIV fusion.Formula:C21H28N2O3Purezza:99.43%Colore e forma:SolidPeso molecolare:356.46C-021
CAS:C 021 dihydrochloride is a potent CCR4 antagonist.Formula:C27H41N5O2Purezza:99.74% - 99.90%Colore e forma:SolidPeso molecolare:467.65Ref: TM-T21870
1mg51,00€2mg71,00€5mg96,00€10mg153,00€25mg303,00€50mg469,00€100mg655,00€1mL*10mM (DMSO)96,00€Maraviroc
CAS:Maraviroc: a CCR5 antagonist blocking HIV-1 entry; IC50s—MIP-1α: 3.3nM, MIP-1β: 7.2nM, RANTES: 5.2nM.Formula:C29H41F2N5OPurezza:97.13% - 99.59%Colore e forma:Brown SolidPeso molecolare:513.67Ref: TM-T6016
5mg51,00€10mg95,00€25mg160,00€50mg273,00€100mg492,00€200mg633,00€500mg998,00€1mL*10mM (DMSO)59,00€
