CCR
I recettori delle chemochine C-C (CCR) sono un gruppo di GPCR che rispondono alle chemochine, molecole segnalatrici che guidano la migrazione delle cellule immunitarie verso i siti di infiammazione o infezione. I CCR svolgono ruoli cruciali nelle risposte immunitarie, nell'infiammazione e nello sviluppo di varie malattie, tra cui disturbi autoimmuni e cancro. La modulazione dell'attività dei CCR è esplorata come strategia terapeutica per condizioni come l'artrite reumatoide, la sclerosi multipla e l'infezione da HIV. Presso CymitQuimica, offriamo una gamma di modulatori CCR di alta qualità per supportare la tua ricerca in immunologia, infiammazione e sviluppo terapeutico.
Trovati 135 prodotti di "CCR"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
ZK 756326
CAS:ZK 756326: Selective CCR8 agonist, IC50 1.8 μM (human), 2.6 μM (mouse), no CCR4/5, CXCR3/4 action, 28-fold selectivity vs 26 GPCRs, anti-HIV fusion.Formula:C21H28N2O3Purezza:99.43%Colore e forma:SolidPeso molecolare:356.46Bindarit
CAS:Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Cost-effective and quality-assured.Formula:C19H20N2O3Purezza:98.35% - 98.55%Colore e forma:SolidPeso molecolare:324.37Ref: TM-T6413
1mg35,00€2mg50,00€5mg75,00€10mg110,00€25mg178,00€50mg314,00€100mg492,00€200mg710,00€1mL*10mM (DMSO)84,00€INCB 3284
CAS:INCB 3284, a potent human CCR2 antagonist with an IC50 of 3.7 nM, is researchable for acute liver failure and inhibits MCP-1/hCCR2 binding.Formula:C26H31F3N4O4Purezza:97.81% - 99.42%Colore e forma:SolidPeso molecolare:520.54Tivumecirnon
CAS:Tivumecirnon (FLX475) is a selective and oral CCR4 antagonist inhibits the infiltration and migration of Treg into the tumour microenvironment, antitumourFormula:C24H27Cl2F3N6OPurezza:99.88%Colore e forma:SolidPeso molecolare:543.41Ref: TM-T69834
1mg171,00€5mg418,00€10mg666,00€25mg1.334,00€50mg2.071,00€100mg2.879,00€1mL*10mM (DMSO)500,00€CCR4 antagonist 3-1
CAS:CCR4 antagonist 3-1 is a weak inhibitor of [125I]TARC binding and CEM cell migration, with IC50 values of 1.7 μM and 6.4 μM, respectively.
Formula:C14H12N2SPurezza:99.53%Colore e forma:SolidPeso molecolare:240.32C-021 dihydrochloride
CAS:C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.Formula:C27H43Cl2N5O2Purezza:98.67%Colore e forma:SolidPeso molecolare:540.57CCR1 antagonist 7
CAS:CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].Formula:C21H24ClN5O3SPurezza:98%Colore e forma:SolidPeso molecolare:461.96CCR1 antagonist 9
CAS:CCR1 antagonist 9 (compound 19e) is a selective CCR1 antagonist based on aziridine. CCR1 inhibition in calcium flux assays.Formula:C20H16FN5O3SPurezza:99.13%Colore e forma:SolidPeso molecolare:425.44Ref: TM-T10710
1mg101,00€5mg241,00€10mg402,00€25mg727,00€50mg1.046,00€100mg1.525,00€1mL*10mM (DMSO)265,00€BMS-457
CAS:BMS-457 is a potent, CCR1-selective antagonist.Formula:C24H35ClN2O4Purezza:98%Colore e forma:SolidPeso molecolare:451JNJ-27141491
CAS:JNJ-27141491 is a potent, noncompetitive antagonist of human CCR2.Formula:C17H15F2N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:379.38GW 766994
CAS:GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment.Formula:C21H24Cl2N4O3Purezza:98.77%Colore e forma:SolidPeso molecolare:451.35CCX354
CAS:CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis.Formula:C22H22ClN7O2Purezza:99.43% - 99.44%Colore e forma:SolidPeso molecolare:451.91BI-6901
CAS:BI-6901 is a CCR10 antagonist. In a mouse model of DNFB exposure hypersensitivity, BI 6901 displays its anti-inflammatory response in a dose-dependent manner.Formula:C23H27N5O3SPurezza:99.83% - 99.94%Colore e forma:SolidPeso molecolare:453.56TAK-220
CAS:TAK-220: Oral CCR5 antagonist. IC50: 3.5 nM (RANTES), 1.4 nM (MIP-1α).Formula:C31H41ClN4O3Purezza:98%Colore e forma:SolidPeso molecolare:553.14MLN3126
CAS:MLN3126: Oral CCR9 blocker, hinders CCL25-triggered chemotaxis/thymocyte calcium influx, IC50 of 6.3 nM.Formula:C21H19ClN2O5SColore e forma:SolidPeso molecolare:446.9AZD-1678
CAS:AZD-1678 is a potent CCR4 receptor antagonist.Formula:C11H8Cl2FN3O3SColore e forma:SolidPeso molecolare:352.17ALK4290
CAS:ALK4290 (AKST4290), a potent oral CCR3 inhibitor with a Ki of 3.2 nM, may treat macular degeneration and Parkinsonism.Formula:C27H34ClN5O3Colore e forma:SolidPeso molecolare:512.04RPT193
CAS:RPT193 is an oral CCR4 inhibitor reducing Th2 cell migration in atopic dermatitis, asthma, and allergies.Formula:C27H34Cl3N5O2Colore e forma:SolidPeso molecolare:566.95CCR8 antagonist 2
CAS:CCR8 antagonist 2 blocks CCR8 activity, mainly on Treg and Th2 cells, for treating related diseases. See WO2022000443A1, compound 220.Formula:C23H30ClN3O3SColore e forma:SolidPeso molecolare:464.02APC-3316 tosylate
CAS:APC-3316 tosylate is a vinyl sulfone cysteine protease inhibitor and selective CCR4 antagonist.Formula:C39H46N4O7S2Colore e forma:SolidPeso molecolare:746.94
