CCR
I recettori delle chemochine C-C (CCR) sono un gruppo di GPCR che rispondono alle chemochine, molecole segnalatrici che guidano la migrazione delle cellule immunitarie verso i siti di infiammazione o infezione. I CCR svolgono ruoli cruciali nelle risposte immunitarie, nell'infiammazione e nello sviluppo di varie malattie, tra cui disturbi autoimmuni e cancro. La modulazione dell'attività dei CCR è esplorata come strategia terapeutica per condizioni come l'artrite reumatoide, la sclerosi multipla e l'infezione da HIV. Presso CymitQuimica, offriamo una gamma di modulatori CCR di alta qualità per supportare la tua ricerca in immunologia, infiammazione e sviluppo terapeutico.
Trovati 165 prodotti per "CCR".
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Denrakibart
Denrakibart is a humanized antibody targeting CCL17 for exploratory research on CCL17/CCR4 immune signaling.Purezza:95%Colore e forma:Odour LiquidPeso molecolare:~148 kDaDenikitug
Denikitug (GS-1811) is an Fc-optimized humanized anti-CCR8 antibody that can bind human CCR8 and antagonize CCL1 signaling, and induces NK-dependent ADCC against CCR8-high-expressing cells, facilitating tumor immunology research centered on Tregs.Purezza:95%Colore e forma:Odour LiquidPeso molecolare:~148 kDaLanerkitug
Lanerkitug (BAY3375968) is a fully humanized anti-CCR8 IgG1 mAb that depletes CCR8+ Tregs via ADCC and ADCP, with potential in solid tumor therapy.Purezza:95%Colore e forma:Odour LiquidPeso molecolare:~148 kDaNebokitug
Nebokitug is a humanized IgG1κ antibody targeting CCL24, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Colore e forma:Odour LiquidCafelkibart
Cafelkibart is a chimeric IgG1κ monoclonal antibody targeting CCR8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Colore e forma:Odour LiquidMLN3126
CAS:MLN3126: Oral CCR9 blocker, hinders CCL25-triggered chemotaxis/thymocyte calcium influx, IC50 of 6.3 nM.Formula:C21H19ClN2O5SColore e forma:SolidPeso molecolare:446.904S-531011
S-531011 is a human IgG1 monoclonal antibody that targets CCR8. It reduces tumor-infiltrating CCR8+ Tregs and exhibits antitumor activity in CT26.WT and EMT6 tumor-bearing mouse models. S-531011 is useful for cancer immunotherapy research. The recommended isotype control is HumanIgG1kappa, Isotype Control.AT008
AT008 is a monoclonal antibody that targets GPCR and inhibits the binding of chemokine ligands to their cell surface receptor, CCR4. [AT008] is applicable in the study of certain hematological cancers and solid tumors.Anti-Human CCR8 Antibody (10A11)
Anti-CCR8 Antibody (10A11) is a humanized IgG1 monoclonal antibody targeting CCR8.HGS004
HGS004 is a humanized IgG4 monoclonal antibody inhibitor targeting CCR5. It exhibits potent antiviral activity against various CCR5-tropic HIV-1 strains, including those resistant to other treatments (such as Maraviroc-resistant strains). HGS004 is applicable for research in HIV-1 infection.Colore e forma:Odour LiquidCCR1 antagonist 7
CAS:CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].Formula:C21H24ClN5O3SPurezza:98%Colore e forma:SolidPeso molecolare:461.96BMS-457
CAS:BMS-457 is a potent, CCR1-selective antagonist.Formula:C24H35ClN2O4Purezza:98%Colore e forma:SolidPeso molecolare:451JNJ-27141491
CAS:JNJ-27141491 is a potent, noncompetitive antagonist of human CCR2.Formula:C17H15F2N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:379.38TAK-220
CAS:TAK-220: Oral CCR5 antagonist. IC50: 3.5 nM (RANTES), 1.4 nM (MIP-1α).Formula:C31H41ClN4O3Purezza:98%Colore e forma:SolidPeso molecolare:553.135AZD-1678
CAS:AZD-1678 is a potent CCR4 receptor antagonist.Formula:C11H8Cl2FN3O3SColore e forma:SolidPeso molecolare:352.17ALK4290
CAS:ALK4290 (AKST4290), a potent oral CCR3 inhibitor with a Ki of 3.2 nM, may treat macular degeneration and Parkinsonism.Formula:C27H34ClN5O3Colore e forma:SolidPeso molecolare:512.044RPT193
CAS:RPT193 is an oral CCR4 inhibitor reducing Th2 cell migration in atopic dermatitis, asthma, and allergies.Formula:C27H34Cl3N5O2Colore e forma:SolidPeso molecolare:566.95CCR2 antagonist 3
CAS:CCR2 antagonist 3 (AZD-2927) is an antagonist of CCR2.Formula:C17H25FN2O2Purezza:99.87%Colore e forma:SolidPeso molecolare:308.391PNU-177864 hydrochloride
CAS:PNU-177864 hydrochloride is a potent, selective and orally active antagonist of dopamine D3 receptor.Formula:C18H22ClF3N2O3SPurezza:99.95%Colore e forma:SolidPeso molecolare:438.89PNU-177864
CAS:PNU-177864 is a selective dopamine D3 receptor antagonist.Formula:C18H21F3N2O3SPurezza:99.92%Colore e forma:SolidPeso molecolare:402.431
