Nrf2
Nrf2 è un fattore di trascrizione che regola l'espressione di proteine antiossidanti ed enzimi di detossificazione, svolgendo un ruolo fondamentale nella difesa cellulare contro lo stress ossidativo e l'infiammazione. L'attivazione della segnalazione Nrf2 fornisce protezione contro varie malattie, tra cui il cancro, la neurodegenerazione e i disturbi cardiovascolari. I modulatori di Nrf2 sono oggetto di studio per le loro potenziali applicazioni terapeutiche nella riduzione dei danni ossidativi e dell'infiammazione. Presso CymitQuimica, offriamo una gamma di modulatori della via Nrf2 di alta qualità per supportare la tua ricerca sullo stress ossidativo, l'infiammazione e la prevenzione delle malattie.
Trovati 80 prodotti per "Nrf2".
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TBE-31
CAS:TBE-31 is a highly potent activator of Nrf2, a liver carcinogenesis blocker and a potent phase 2 cytoprotective pathway inducer.Formula:C21H18N2O2Colore e forma:SolidPeso molecolare:330.38TPNA10168
CAS:TPNA10168 ,with CAS No. 957942-34-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. TPNA10168 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C9H9ClO2S2Colore e forma:SolidPeso molecolare:248.75Nrf2 degrader 30
CAS:Nrf2 degrader 30 PROTAC inhibits Nrf2 ubiquitination and proteasomal degradation, enhancing activity for antioxidant and protective mechanisms。Formula:C42H41FN8O7SPurezza:97.73% - 98.81%Colore e forma:SolidPeso molecolare:820.89Nrf2/HO-1 activator 3
Nrf2/HO-1 Activator 3 (Compound C3a) is an activator of the Nrf2 signaling pathway that facilitates the translocation of Nrf2 into the nucleus and enhances the expression of heme oxygenase-1 (HO-1). In H9c2 cardiomyocytes subjected to H2O2 or high glucose stimulation, Nrf2/HO-1 Activator 3 inhibits the excessive expression of ROS and MDA, suppressing cell viability and colony formation, thereby exhibiting antioxidant activity.Formula:C27H26N2O6Colore e forma:SolidPeso molecolare:474.51Butan-1-amine hydrochloride
CAS:1-Butylamine hydrochloride,butylamine, a potential agonist of Nrf2/ARE (Nuclear Factor Erythroid 2 Associated Factor 2/Antioxidant Response Element).Formula:C4H12ClNColore e forma:SolidPeso molecolare:109.6His-Pro
CAS:His-Pro is a dipeptide consisting of histidyl and proline.Formula:C11H16N4O3Purezza:98%Colore e forma:SolidPeso molecolare:252.2717-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
CAS:Aspirin-enhanced COX-2 metabolite of DHA, activates Nrf2 and PPARγ, inhibits inflammation, with EC50 ~200 nM, effective at 5-25 μM.Formula:C22H30O3Colore e forma:SolidPeso molecolare:342.479TAT 14
CAS:TAT 14: a 14-mer peptide Nrf2 activator, anti-inflammatory, boosts Nrf2 protein, targets Keap1, no effect on mRNA.Formula:C137H230N48O39Purezza:98%Colore e forma:SolidPeso molecolare:3173.59Nrf2 activator 18
Nrf2 activator 18 (Compound 11a) is an orally active activator of the Keap1/Nrf2/HO-1 signaling pathway, promoting Nrf2 nuclear translocation and enhancing antioxidant effects. It inhibits IL-6 release with an IC50 of 4.816 μM. In a mouse model of PM2.5-induced lung injury, Nrf2 activator 18 demonstrates anti-inflammatory activity.Formula:C23H24FN3OColore e forma:SolidPeso molecolare:377.45S217879
CAS:S217879 is a potent and selective activator of NRF2 that disrupts the KEAP1-NRF2 interaction, resulting in significant activation of the NRF2 pathway.Formula:C30H32N4O7SColore e forma:SolidPeso molecolare:592.67ML334
CAS:ML334 (LH601A) is an NRF2 activator that inhibits cardiac fibroblast activation and proliferation ameliorating myocardial infarction-induced cardiac fibrosis.Formula:C26H26N2O5Purezza:98.06% - 98.06%Colore e forma:SolidPeso molecolare:446.49KI696 isomer
CAS:KI696 isomer is an isomer of KI696, a low affinity probe for the study of immune and metabolic diseases.Formula:C28H30N4O6SPurezza:99.98%Colore e forma:White SolidPeso molecolare:550.63Ref: TM-T11758
1mg87,00€5mg264,00€1mL*10mM (DMSO)289,00€10mg442,00€25mg892,00€50mg1.198,00€100mg1.575,00€I-152
CAS:Bepranemab (UCB 0107) is a humanized IgG monoclonal antibody against tau for the study of Alzheimer's disease (AD) and tau proteinopathies.Formula:C9H16N2O3S2Purezza:98.36%Colore e forma:SolidPeso molecolare:264.37Anti-NFE2L2 Antibody (9K94)
Anti-NFE2L2 Antibody (9K94) is a Mouse antibody targeting NFE2L2. Anti-NFE2L2 Antibody (9K94) can be used in ELISA, WB, IHC, IF, FCM.Purezza:>95%Colore e forma:Odour LiquidAnti-Phospho-NFE2L2 (Ser40) Antibody (6V851)
Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) is an antibody targeting Phospho-NFE2L2 (Ser40). Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) can be used in ELISA, WB, IHC, IF.Colore e forma:Odour LiquidAnti-NFE2L2 Antibody (6K859)
Anti-NFE2L2 Antibody (6K859) is an antibody targeting NFE2L2. Anti-NFE2L2 Antibody (6K859) can be used in ELISA, IF.Colore e forma:Odour LiquidDimethyl fumarate-D6
CAS:Dimethyl fumarate-D6 is a deuterium labeled Dimethyl fumarate (T0492). can induces upregulation of antioxidant gene expression.Formula:C6H8O4Purezza:98%Colore e forma:SolidPeso molecolare:150.16CBR-470-2
CAS:CBR-470-2 activates NRF2 signaling, aiding in glycolysis research.Formula:C12H13Cl2NO6S2Colore e forma:SolidPeso molecolare:402.26Artemisitene
CAS:Artemisitene, an oxidized antimalarial derivative of Artemisinin, stems from precursors like Artemisinin B and Artemisinic acid.Formula:C15H20O5Purezza:99.58%Colore e forma:SolidPeso molecolare:280.32Ref: TM-T21065
1mg89,00€5mg177,00€1mL*10mM (DMSO)203,00€10mg313,00€25mg530,00€50mg757,00€100mg1.044,00€Kinsenoside
CAS:Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.Formula:C10H16O8Purezza:99.2% - 99.92%Colore e forma:SolidPeso molecolare:264.23
