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Nrf2

Nrf2

Nrf2 è un fattore di trascrizione che regola l'espressione di proteine antiossidanti ed enzimi di detossificazione, svolgendo un ruolo fondamentale nella difesa cellulare contro lo stress ossidativo e l'infiammazione. L'attivazione della segnalazione Nrf2 fornisce protezione contro varie malattie, tra cui il cancro, la neurodegenerazione e i disturbi cardiovascolari. I modulatori di Nrf2 sono oggetto di studio per le loro potenziali applicazioni terapeutiche nella riduzione dei danni ossidativi e dell'infiammazione. Presso CymitQuimica, offriamo una gamma di modulatori della via Nrf2 di alta qualità per supportare la tua ricerca sullo stress ossidativo, l'infiammazione e la prevenzione delle malattie.

Trovati 84 prodotti per "Nrf2".

prodotti per pagina.
  • Trilobatin
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    Trilobatin

    CAS:
    Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially
    Formula:C21H24O10
    Purezza:97.16%
    Colore e forma:Solid
    Peso molecolare:436.41

    Ref: TM-T2S0731

  • AT 14 acetate
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    AT 14 acetate

    TAT 14 acetate, a 14-mer peptide, activates Nrf2, has anti-inflammatory effects, and targets Keap1 without altering Nrf2 mRNA.
    Formula:C139H234N48O41
    Purezza:96.9%
    Colore e forma:Solid
    Peso molecolare:3233.64

    Ref: TM-TP2109L

  • AEM1
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    AEM1

    CAS:
    AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer.
    Formula:C20H14FN3O2S
    Purezza:98.37% - 99.88%
    Colore e forma:Solid
    Peso molecolare:379.407

    Ref: TM-T8979

  • ML162
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    ML162

    CAS:
    ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.
    Formula:C23H22Cl2N2O3S
    Purezza:98.42% - 99.55%
    Colore e forma:Solid
    Peso molecolare:477.40

    Ref: TM-T8970

  • Brusatol
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    Brusatol

    CAS:
    Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.
    Formula:C26H32O11
    Purezza:99.35% - 99.95%
    Colore e forma:Solid
    Peso molecolare:520.5257

    Ref: TM-TQ0211

  • Diroximel fumarate
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    Diroximel fumarate

    CAS:
    Diroximel fumarate (Diroximel Fumarete), a prodrug of monomethyl fumarate in a controlled-release formulation, rapidly and potently converts to MMF in the body.
    Formula:C11H13NO6
    Purezza:99.8% - 99.88%
    Colore e forma:Solid
    Peso molecolare:255.224

    Ref: TM-T4271

  • Kinsenoside
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    Kinsenoside

    CAS:
    Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.
    Formula:C10H16O8
    Purezza:99.2% - 99.92%
    Colore e forma:Solid
    Peso molecolare:264.2292

    Ref: TM-T3849

  • Artemisitene
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    Artemisitene

    CAS:
    Artemisitene, an oxidized antimalarial derivative of Artemisinin, stems from precursors like Artemisinin B and Artemisinic acid.
    Formula:C15H20O5
    Purezza:99.58%
    Colore e forma:Solid
    Peso molecolare:280.3163

    Ref: TM-T21065

  • CBR-470-1
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    CBR-470-1

    CAS:
    CBR-470-1 is a glycolytic phosphoglycerate kinase 1 inhibitor and Nrf2 activator that exhibits neuroprotective activity by activating the Keap1-Nrf2 cascade.
    Formula:C14H20ClNO4S2
    Purezza:98.87%
    Colore e forma:Solid
    Peso molecolare:365.9

    Ref: TM-T40063

  • Nrf2 activator-4
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    Nrf2 activator-4

    CAS:
    Nrf2 activator-4 is an Nrf2 activator for the treatment of fatty liver disease associated with metabolic dysfunction in humans.
    Formula:C23H24ClF3N2O3
    Purezza:98.53% - 98.89%
    Colore e forma:Solid
    Peso molecolare:468.896

    Ref: TM-T63016

  • Nrf2-Activator-12G
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    Nrf2-Activator-12G

    CAS:
    Nrf2-Activator-12G is a potent Nrf-2 activator.
    Formula:C15H13ClO3S
    Purezza:99.92%
    Colore e forma:White Solid
    Peso molecolare:308.78

    Ref: TM-T24546

  • MSU38225
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    MSU38225

    CAS:
    MSU38225, an Nrf-2 inhibitor, elevates reactive oxygen species (ROS) levels and suppresses the proliferation of human lung cancer cells.
    Formula:C21H19N3
    Colore e forma:Solid
    Peso molecolare:313.4

    Ref: TM-T79146

  • (+)-DHMEQ
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    (+)-DHMEQ

    CAS:
    (+)-DHMEQ is an antioxidant transcription factor Nrf2 activator. (+)-DHMEQ is the enantiomer of (-)-DHMEQ.
    Formula:C13H11NO5
    Colore e forma:Solid
    Peso molecolare:261.2301

    Ref: TM-T13462

  • MIND4-17
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    MIND4-17

    CAS:
    MIND4-17 activates NRF2 by binding Keap1 C151, blocking Keap1-Nrf2, stabilizes Nrf2, and promotes its nuclear entry, with strong antioxidant effects.
    Formula:C20H15N5O3S
    Colore e forma:Solid
    Peso molecolare:405.43

    Ref: TM-T69401

  • Keap1-Nrf2-IN-12
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    Keap1-Nrf2-IN-12

    CAS:
    eap1-Nrf2-IN-12 is a potent inhibitor of Keap1-Nrf2 (IC50: 2.30 μM). eap1-Nrf2-IN-12 is metabolically stable in human liver microsomes.
    Formula:C26H28N2O10S2
    Colore e forma:Solid
    Peso molecolare:592.64

    Ref: TM-T64190

  • Keap1-Nrf2-IN-13
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    Keap1-Nrf2-IN-13

    CAS:
    Keap1-Nrf2-IN-13 is a Keap1-Nrf2 PPI inhibitor (IC₅₀ = 0.15 µM) that binds Keap1 polar residues (Asn414, Arg415, Arg483, Gln530).
    Formula:C28H32N2O10S2
    Colore e forma:Solid
    Peso molecolare:620.69

    Ref: TM-T72706

  • Nrf2 activator-5
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    Nrf2 activator-5

    CAS:
    Nrf2 activator-5 combats oxidative stress and inflammation in microglia, with potent antioxidant effects.
    Formula:C25H30Cl2O6
    Colore e forma:Solid
    Peso molecolare:497.41

    Ref: TM-T63364

  • Keap1-Nrf2-IN-14
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    Keap1-Nrf2-IN-14

    CAS:
    Keap1-Nrf2-IN-14, a KEAP1-NRF2 inhibitor (IC50: 75 nM, Kd: 24 nM), boosts NRF2 gene expression, antioxidative and anti-inflammatory response.
    Formula:C30H29NO8S
    Colore e forma:Solid
    Peso molecolare:563.62

    Ref: TM-T63987

  • NXPZ-2
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    NXPZ-2

    CAS:
    NXPZ-2 is an orally active Keap1-Nrf2 PPI inhibitor (Kᵢ = 95 nM, EC₅₀ = 120–170 nM) that upregulates Nrf2 and alleviates Aβ-induced cognitive impairment.
    Formula:C27H27N5O7S2
    Colore e forma:Solid
    Peso molecolare:597.66

    Ref: TM-T64214

  • SPC-180002
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    SPC-180002

    CAS:
    SPC-180002, a dual SIRT1/3 inhibitor, exhibits IC50 values of 1.13 and 5.41 μM for SIRT1 and SIRT3, respectively.
    Formula:C18H23NO4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:317.38

    Ref: TM-T79601