Nrf2
Nrf2 è un fattore di trascrizione che regola l'espressione di proteine antiossidanti ed enzimi di detossificazione, svolgendo un ruolo fondamentale nella difesa cellulare contro lo stress ossidativo e l'infiammazione. L'attivazione della segnalazione Nrf2 fornisce protezione contro varie malattie, tra cui il cancro, la neurodegenerazione e i disturbi cardiovascolari. I modulatori di Nrf2 sono oggetto di studio per le loro potenziali applicazioni terapeutiche nella riduzione dei danni ossidativi e dell'infiammazione. Presso CymitQuimica, offriamo una gamma di modulatori della via Nrf2 di alta qualità per supportare la tua ricerca sullo stress ossidativo, l'infiammazione e la prevenzione delle malattie.
Trovati 78 prodotti di "Nrf2"
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Diroximel fumarate
CAS:<p>Diroximel fumarate (Diroximel Fumarete), a prodrug of monomethyl fumarate in a controlled-release formulation, rapidly and potently converts to MMF in the body.</p>Formula:C11H13NO6Purezza:99.8% - 99.88%Colore e forma:SolidPeso molecolare:255.22Trilobatin
CAS:<p>Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially</p>Formula:C21H24O10Purezza:97.16%Colore e forma:SolidPeso molecolare:436.414-Octyl itaconate
CAS:<p>4-Octyl Itaconate is a cell-permeable derivative of Itaconate, an anti-inflammatory metabolite.</p>Formula:C13H22O4Purezza:99.3% - 99.94%Colore e forma:SolidPeso molecolare:242.31Kinsenoside
CAS:<p>Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.</p>Formula:C10H16O8Purezza:99.2% - >99.99%Colore e forma:SolidPeso molecolare:264.23Brusatol
CAS:<p>Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.</p>Formula:C26H32O11Purezza:99.35% - 99.95%Colore e forma:SolidPeso molecolare:520.53CBR-470-1
CAS:<p>CBR-470-1 is a glycolytic phosphoglycerate kinase 1 inhibitor and Nrf2 activator that exhibits neuroprotective activity by activating the Keap1-Nrf2 cascade.</p>Formula:C14H20ClNO4S2Purezza:98.87%Colore e forma:SolidPeso molecolare:365.9L-Cystine dihydrochloride
CAS:<p>L-Cystine dihydrochloride, a sulfur-based glutathione precursor, maintains GSH balance, used in cell culture.</p>Formula:C6H14Cl2N2O4S2Purezza:99.58%Colore e forma:SolidPeso molecolare:313.22MIND4-17
CAS:<p>MIND4-17 activates NRF2 by binding Keap1 C151, blocking Keap1-Nrf2, stabilizes Nrf2, and promotes its nuclear entry, with strong antioxidant effects.</p>Formula:C20H15N5O3SColore e forma:SolidPeso molecolare:405.43Nrf2-Activator-12G
CAS:<p>Nrf2-Activator-12G is a potent Nrf-2 activator.</p>Formula:C15H13ClO3SPurezza:98%Colore e forma:SolidPeso molecolare:308.78MSU38225
CAS:<p>MSU38225, an Nrf-2 inhibitor, elevates reactive oxygen species (ROS) levels and suppresses the proliferation of human lung cancer cells.</p>Formula:C21H19N3Colore e forma:SolidPeso molecolare:313.4(+)-DHMEQ
CAS:<p>(+)-DHMEQ is an antioxidant transcription factor Nrf2 activator. (+)-DHMEQ is the enantiomer of (-)-DHMEQ.</p>Formula:C13H11NO5Colore e forma:SolidPeso molecolare:261.23Dihydrolipoic acid
CAS:<p>Dihydrolipoic acid (USAF XR-12), a dithiol carboxylic acid, is a potent antioxidant active against various reactive oxygen species at 0.01-0.5 mM.</p>Formula:C8H16O2S2Purezza:97.51%Colore e forma:Yellow To Orange LiquidPeso molecolare:208.34Keap1-Nrf2-IN-12
CAS:<p>eap1-Nrf2-IN-12 is a potent inhibitor of Keap1-Nrf2 (IC50: 2.30 μM). eap1-Nrf2-IN-12 is metabolically stable in human liver microsomes.</p>Formula:C26H28N2O10S2Colore e forma:SolidPeso molecolare:592.64Keap1-Nrf2-IN-13
CAS:<p>Keap1-Nrf2-IN-13 is a PPI inhibitor (IC50: 0.15 μM) that binds Keap1 strongly, useful for oxidative stress and inflammation research.</p>Formula:C28H32N2O10S2Colore e forma:SolidPeso molecolare:620.69Nrf2 activator-5
CAS:<p>Nrf2 activator-5 combats oxidative stress and inflammation in microglia, with potent antioxidant effects.</p>Formula:C25H30Cl2O6Colore e forma:SolidPeso molecolare:497.41Keap1-Nrf2-IN-14
CAS:<p>Keap1-Nrf2-IN-14, a KEAP1-NRF2 inhibitor (IC50: 75 nM, Kd: 24 nM), boosts NRF2 gene expression, antioxidative and anti-inflammatory response.</p>Formula:C30H29NO8SColore e forma:SolidPeso molecolare:563.62NXPZ-2
CAS:<p>NXPZ-2, an oral Keap1-Nrf2 PPI inhibitor (Ki: 95 nM, EC50: 120-170 nM), may improve cognition and neuron health in AD.</p>Formula:C27H27N5O7S2Colore e forma:SolidPeso molecolare:597.66SPC-180002
CAS:<p>SPC-180002, a dual SIRT1/3 inhibitor, exhibits IC50 values of 1.13 and 5.41 μM for SIRT1 and SIRT3, respectively.</p>Formula:C18H23NO4Purezza:98%Colore e forma:SolidPeso molecolare:317.38Stigmane B
<p>Stigmane B activates Nrf2, decreases apoptosis and ROS, boosts antioxidants, and is neuroprotective.</p>Formula:C21H30O4Colore e forma:SolidPeso molecolare:346.46BPK-29
CAS:<p>BPK-29 disrupts NR0B1 binding and modifies C274, inhibiting growth in KEAP1-mutant cancers.</p>Formula:C26H32ClN3O3Purezza:98%Colore e forma:SolidPeso molecolare:470
