TLR
I recettori Toll-like (TLR) sono una classe di proteine che svolgono un ruolo fondamentale nel sistema immunitario innato riconoscendo i pattern molecolari associati ai patogeni (PAMP) e iniziando risposte immunitarie. I TLR sono coinvolti nel rilevamento di un'ampia gamma di patogeni, tra cui batteri, virus e funghi, e sono essenziali per l'attivazione delle vie di segnalazione infiammatorie. La disregolazione della segnalazione dei TLR è associata a malattie infiammatorie croniche, disturbi autoimmuni e cancro. Presso CymitQuimica, offriamo una varietà di modulatori TLR di alta qualità per supportare la tua ricerca sull'immunità innata, l'infiammazione e le malattie infettive.
Trovati 76 prodotti di "TLR"
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RKH
PKH is a TLR4 antagonist, and it is a new tripeptide derived from Akkermansia muciniphila. PKH reduces inflammation-related cell activation and the overproduction of pro-inflammatory factors induced by sepsis.Formula:C18H33N9O4Peso molecolare:439.26555IPH33
IPH33 is a human monoclonal antibody (mAb) targeting TLR3/CD283. It is useful for research in cancer and inflammation.Colore e forma:Odour LiquidTomaralimab
CAS:<p>Tomaralimab (OPN-305) is a humanized IgG4 monoclonal antibody targeting TLR2. Tomarlimab is used to study myelodysplastic syndromes (MDS).</p>Purezza:100% (SEC-HPLC) - > 95%Colore e forma:LiquidPeso molecolare:145.32 kDaCU-115
CAS:<p>CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM for TLR8 and TLR7, respectively.</p>Formula:C21H11F7INO2Purezza:99.96%Colore e forma:SolidPeso molecolare:569.21TLR8 agonist 8
CAS:<p>TLR8 agonist8 (Compound II-72) is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of 0.25-1 μM. It demonstrates stability in both human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist8 exhibits antitumor activity, achieving a tumor growth inhibition (TGI) rate of 89%.</p>Formula:C53H63N11O10Colore e forma:SolidPeso molecolare:1014.14TLR8 agonist 7
CAS:<p>TLR8 agonist7 is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of less than 250 nM. It remains stable in human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist7 demonstrates antitumor activity, achieving a tumor growth inhibition (TGI) rate of 98%.</p>Formula:C54H63N9O16Colore e forma:SolidPeso molecolare:1094.13(R)-Thalidomide-pyrrolidine-C-piperidine-Ph-NH2
(R)-Thalidomide-pyrrolidine-C-piperidine-Ph-NH2 serves as the E3 ubiquitin ligase ligand and linker for PROTAC(R)-NX-2127, utilized in cancer research.Formula:C29H33N5O4Colore e forma:SolidPeso molecolare:515.6Toll-like receptor modulator
CAS:Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.Formula:C15H13F5N2O2Purezza:98%Colore e forma:SolidPeso molecolare:348.27TLR7 agonist 3
CAS:<p>TLR7 agonist 3 is a Toll-like receptor 7 (TLR7) agonist that has anticancer activity and is used in the study of diseases of the immune system.</p>Formula:C18H24N4OPurezza:99.27%Colore e forma:SolidPeso molecolare:312.41Neoseptin-3
CAS:Neoseptin-3 is a novel small molecule agonist of mouse mTLR4/MD2 with EC50=18.5 μM that does not activate human TLR4/MD2.Formula:C29H34N2O4Purezza:98%Colore e forma:SolidPeso molecolare:474.59Desethyl chloroquine diphosphate
CAS:Desethyl chloroquine diphosphate is the active metabolite of Desethylchloroquine, an inhibitor of TLRs with antiplasmodial activity and inhibition of autophagy.Formula:C16H28ClN3O8P2Purezza:99.72%Colore e forma:SolidPeso molecolare:487.81Pam3CSK4
CAS:Pam3CSK4 is a synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs.Formula:C81H156N10O13SPurezza:98%Colore e forma:SolidPeso molecolare:1510.23Pam3CSK4 TFA (112208-00-1 free base)
CAS:<p>Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) is a Toll-like receptor 1/2 agonist with EC50 of 0.47 ng/mL for human TLR1/2.Cost-effective and quality-assured.</p>Formula:C87H159F9N10O19SPurezza:96.4% - 99.01%Colore e forma:SolidPeso molecolare:1852.33TLR7 agonist 2
CAS:<p>TLR7 agonist 2 (TLR7-IN-1) is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 μM).</p>Formula:C17H16N6O2Purezza:99.33%Colore e forma:SolidPeso molecolare:336.35TLR7/8 agonist 1
CAS:<p>TLR7/8 agonist 1 is a toll-like receptor TLR7/TLR8 agonist with anticancer and antiviral activities and can be used to study immune-related diseases.</p>Formula:C22H25N5Purezza:99.4%Colore e forma:SolidPeso molecolare:359.47Telratolimod
CAS:<p>Telratolimod (MEDI9197) is a toll-like receptors 7/8 agonist. It has an antitumor activity.</p>Formula:C36H59N5O2Purezza:98.61%Colore e forma:SolidPeso molecolare:593.89Enpatoran
CAS:<p>Enpatoran is an inhibitor of TLR7(IC50 = 11.1 nM) and TLR8(IC50 = 24.1 nM).</p>Formula:C16H15F3N4Purezza:97.08% - 99.38%Colore e forma:SolidPeso molecolare:320.31Gardiquimod
CAS:<p>Gardiquimod, an imidazoquinoline TLR7 agonist, inhibits HIV-1 in macrophages and PBMCs under 10μM.</p>Formula:C17H23N5OPurezza:98.02% - 99.68%Colore e forma:SolidPeso molecolare:313.4CU-CPT-8m
CAS:CU-CPT-8m (TLR8-specific antagonist) is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)Formula:C14H12N4OPurezza:99.00%Colore e forma:SolidPeso molecolare:252.27SM-324405
CAS:SM-324405 is an agonist of TLR7.Formula:C19H23N5O4Purezza:97.83%Colore e forma:SolidPeso molecolare:385.42
