TLR
I recettori Toll-like (TLR) sono una classe di proteine che svolgono un ruolo fondamentale nel sistema immunitario innato riconoscendo i pattern molecolari associati ai patogeni (PAMP) e iniziando risposte immunitarie. I TLR sono coinvolti nel rilevamento di un'ampia gamma di patogeni, tra cui batteri, virus e funghi, e sono essenziali per l'attivazione delle vie di segnalazione infiammatorie. La disregolazione della segnalazione dei TLR è associata a malattie infiammatorie croniche, disturbi autoimmuni e cancro. Presso CymitQuimica, offriamo una varietà di modulatori TLR di alta qualità per supportare la tua ricerca sull'immunità innata, l'infiammazione e le malattie infettive.
Trovati 76 prodotti di "TLR"
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CU-CPT9b
CAS:<p>CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM).</p>Formula:C16H13NO2Purezza:98.1%Colore e forma:SolidPeso molecolare:251.28MD2-IN-1
CAS:MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189 μM for the recombinant human MD2 (rhMD2).Formula:C20H22O6Purezza:99.87%Colore e forma:SolidPeso molecolare:358.39C29
CAS:C29 inhibits TLR2/1 and TLR2/6 in human cells, but only TLR2/1 in mouse macrophages.Formula:C16H15NO4Purezza:96.34% - 97.37%Colore e forma:SolidPeso molecolare:285.29TLR3-IN-1
CAS:<p>TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor. It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the TNF-α and IL-1β.</p>Formula:C18H13ClFNO3SPurezza:98.56%Colore e forma:SolidPeso molecolare:377.82CU-CPT-9a
CAS:<p>CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-</p>Formula:C17H15NO2Purezza:99.01%Colore e forma:SolidPeso molecolare:265.31TLR7/8/9-IN-1
CAS:TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.Formula:C27H37N3O2Purezza:99.56%Colore e forma:SolidPeso molecolare:435.6TLR4-IN-C34
CAS:<p>TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis</p>Formula:C17H27NO9Purezza:99.69%Colore e forma:SolidPeso molecolare:389.4Bropirimine
CAS:Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.Formula:C10H8BrN3OPurezza:99.01%Colore e forma:SolidPeso molecolare:266.091V209
CAS:<p>1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.</p>Formula:C16H17N5O5Purezza:99.61%Colore e forma:SolidPeso molecolare:359.34TH1020
CAS:TH1020 is a novel Inhibitor of Toll-Like Receptor 5 (TLR5)/Flagellin Complex with promising activity (IC50 =0.85±0.12 μm) and specificity.Formula:C23H15N7S2Purezza:99.23%Colore e forma:SolidPeso molecolare:453.54Motolimod
CAS:<p>Motolimod (VTX-378) (VTX-2337) is an effective and specific Toll-like receptor (TLR) 8 agonist (EC50: 100 nM), > 50-fold selectivity over TLR7.</p>Formula:C28H34N4O2Purezza:97.43% - 99.66%Colore e forma:SolidPeso molecolare:458.6TLR7/8 agonist 1 dihydrochloride
CAS:TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) is a TLR7/8 agonist which shows prominent immunostimulatory activities.Formula:C22H27Cl2N5Purezza:98.33%Colore e forma:SolidPeso molecolare:432.39Robinin
CAS:Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.Formula:C33H40O19Purezza:98.78% - 99.13%Colore e forma:SolidPeso molecolare:740.66Paridiprubart
CAS:<p>Paridiprubart (NI-0101) is a humanised monoclonal antibody targeting TLR4, ameliorative effects in COVID-19 patients with ARDS and rheumatoid arthritis.</p>Purezza:95% - 95%Colore e forma:LiquidAZD8848
CAS:AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.Formula:C29H43N7O5Colore e forma:SolidPeso molecolare:569.7TLR7 agonist 1
CAS:TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).Formula:C21H25N5OPurezza:98%Colore e forma:SolidPeso molecolare:363.46CL264
CAS:CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.Formula:C19H23N7O4Purezza:98.01%Colore e forma:SolidPeso molecolare:413.43DSR-6434
CAS:<p>DSR-6434 is a selective agonist of TLR7 with antitumor effect. DSR-6434 exhibits EC50s of 7.2 nM and 4.6 nM for human and mouse.</p>Formula:C19H28N8O2Purezza:99.78%Colore e forma:SolidPeso molecolare:400.48AXC-715 trihydrochloride
CAS:AXC-715 trihydrochloride is a TLR7/8 agonist used to make PD-L1 adjuvanted antibody immunocouplings.Formula:C18H28Cl3N5Purezza:99.87%Colore e forma:SolidPeso molecolare:420.81AT791
CAS:AT791 is an orally available TLR7 and TLR9 inhibitor, suppressing TLR7 and TLR9 signaling, used in autoimmune lupus research.Formula:C23H31N3O3Purezza:99.88%Colore e forma:SolidPeso molecolare:397.51
