JNK
Le JNK (c-Jun N-terminal kinases) sono un sottogruppo della famiglia MAPK che rispondono a stimoli di stress, come citochine, radiazioni ultraviolette e shock termico, e sono coinvolte nel controllo dell'apoptosi, dell'infiammazione e delle risposte immunitarie. La segnalazione JNK è cruciale per la regolazione delle risposte cellulari allo stress ed è stata implicata in varie malattie, tra cui disturbi neurodegenerativi, cancro e condizioni infiammatorie. Presso CymitQuimica, offriamo una gamma di modulatori della via JNK per supportare la tua ricerca sulla segnalazione dello stress, l'apoptosi e la patologia delle malattie.
Trovati 102 prodotti di "JNK"
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SU3327
CAS:SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).Formula:C5H3N5O2S3Purezza:98.39%Colore e forma:SolidPeso molecolare:261.3Urolithin B
CAS:Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropicalFormula:C13H8O3Purezza:99.45%Colore e forma:SolidPeso molecolare:212.2JNK-IN-13
CAS:<p>JNK-IN-13 is a JNK inhibitor that inhibits JNK3 and JNK2 and can be used in the study of diabetes, inflammation, and neurological disorders.</p>Formula:C13H7ClN4SPurezza:98.74%Colore e forma:SolidPeso molecolare:286.74Mefloquine hydrochloride
CAS:Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Formula:C17H17ClF6N2OPurezza:99% - 99.99%Colore e forma:Off-White To Yellow SolidPeso molecolare:414.77NBDHEX
CAS:NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).Formula:C12H15N3O4SPurezza:97.38%Colore e forma:SolidPeso molecolare:297.33Metacetamol
CAS:Metacetamol, a non-toxic acetaminophen derivative, is an OTC analgesic/antipyretic and synthesis intermediate.Formula:C8H9NO2Purezza:99.76% - 99.90%Colore e forma:Physical Description Light Gray Solid (Ntp 1992)Peso molecolare:151.16Tanzisertib
CAS:Tanzisertib (CC-930) (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity.Formula:C21H23F3N6O2Purezza:98.66% - 99.28%Colore e forma:SolidPeso molecolare:448.44Chloramphenicol
CAS:<p>Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.</p>Formula:C11H12Cl2N2O5Purezza:99.6% - 99.84%Colore e forma:Needles Or Elongated Plates From Water Or Ethylene Dichloride SolidPeso molecolare:323.13Mefloquine
CAS:<p>Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.</p>Formula:C17H16F6N2OPurezza:99.89%Colore e forma:SolidPeso molecolare:378.31SP 600125, negative control
CAS:<p>SP 600125, negative control is a methylated analog of SP 600125 and can be used as a negative control for SP 600125.</p>Formula:C15H10N2OPurezza:≥98%Colore e forma:SolidPeso molecolare:234.25JNK-IN-18
JNK-IN-18 (compound 23b) is a potent inhibitor of JNK1, boasting an IC50 of 2 nM. It demonstrates superior efficacy when compared to its IC50 values of 125 nM for JNK2 and 98 nM for BRAF(V600E).Colore e forma:Odour SolidAS601245.2TFA (345987-15-7 free base)
CAS:AS601245.2TFA (345987-15-7 free base) (AS601245.2TFA) is a cell-permeable Inhibitor of JNK (IC50s of 150, 220, and 70 nM for hJNK1, hJNK2, and hJNK3,Formula:C24H18F6N6O4SPurezza:98%Colore e forma:SoildPeso molecolare:600.50JNK-1-IN-3
CAS:JNK-1-IN-3 (Compound 9e) downregulates JNK1 and phosphorylated JNK1, reduces c-Jun and c-Fos expression in tumours, and restores p53 activity.Formula:C19H17FN4O3Purezza:97.551%Colore e forma:SolidPeso molecolare:368.36D-JBD19
CAS:D-JBD19 is a non-permeable peptide with neuroprotective effects.Formula:C99H164N32O28Purezza:98%Colore e forma:SolidPeso molecolare:2250.597JTP10-△-TATi TFA
JTP10-△-TATi TFA is a selective inhibitor of JNK2 peptide (IC50: 92 nM), exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3.Formula:C120H213F3N48O28Purezza:98%Colore e forma:SolidPeso molecolare:2833.28L-JNKI-1
L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies.Formula:C164H286N66O40Purezza:98%Colore e forma:SolidPeso molecolare:3822.44JNK3 inhibitor-7
Potent, oral JNK3 inhibitor-7 crosses blood-brain barrier, IC50: 53 nM (JNK3), offers neuroprotection, potential in AD research.Formula:C32H31N7O3Colore e forma:SolidPeso molecolare:561.63OVA-E1 peptide
CAS:OVA-E1 peptide, as SIINFEKL variant, triggers similar p38/JNK activation in mutant and normal thymocytes.Formula:C47H76N10O14Colore e forma:SolidPeso molecolare:1005.181MAP4K4-IN-6
MAP4K4-IN-6 (Compound 15f) is a MAP4K4 inhibitor with an IC50 of 80 nM. It reduces the phosphorylation of c-Jun and exhibits neuroprotective effects. Additionally, MAP4K4-IN-6 enhances the vitality of motor neurons and can be utilized in the study of amyotrophic lateral sclerosis (ALS).Colore e forma:Odour SolidJNK3 inhibitor-8
JNK3 inhibitor-8: potent, selective, oral, BBB-penetrating, IC50: JNK3=21 nM, JNK2=2203 nM, JNK1>10,000 nM; potential in Alzheimer's research.Formula:C32H30FN7O3Colore e forma:SolidPeso molecolare:579.62
