JNK
Le JNK (c-Jun N-terminal kinases) sono un sottogruppo della famiglia MAPK che rispondono a stimoli di stress, come citochine, radiazioni ultraviolette e shock termico, e sono coinvolte nel controllo dell'apoptosi, dell'infiammazione e delle risposte immunitarie. La segnalazione JNK è cruciale per la regolazione delle risposte cellulari allo stress ed è stata implicata in varie malattie, tra cui disturbi neurodegenerativi, cancro e condizioni infiammatorie. Presso CymitQuimica, offriamo una gamma di modulatori della via JNK per supportare la tua ricerca sulla segnalazione dello stress, l'apoptosi e la patologia delle malattie.
Trovati 102 prodotti di "JNK"
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IMM-H007
CAS:IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expressionFormula:C22H23N5O8Purezza:97.73%Colore e forma:SolidPeso molecolare:485.45AS601245
CAS:AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.Formula:C20H16N6SPurezza:98% - 99.02%Colore e forma:SolidPeso molecolare:372.45JNK Inhibitor VIII
CAS:<p>JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2,</p>Formula:C18H20N4O4Purezza:98.93%Colore e forma:SolidPeso molecolare:356.38Taurochenodeoxycholic Acid
CAS:Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.Formula:C26H45NO6SPurezza:99.53% - 99.86%Colore e forma:SolidPeso molecolare:499.7DB07268
CAS:<p>DB07268 is a potent and selective JNK1 inhibitor.</p>Formula:C17H15N5O2Purezza:98.2% - 98.91%Colore e forma:SolidPeso molecolare:321.33SP600125
CAS:SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitiveFormula:C14H8N2OPurezza:97.63% - 99.82%Colore e forma:SolidPeso molecolare:220.23BI-78D3
CAS:<p>BI-78D3, a competitive JNK inhibitor. IC50 of BI-78D3 is 280 nM that displays > 100 fold selectivity over p38α, and have no activity at mTOR and PI-3K.</p>Formula:C13H9N5O5S2Purezza:97.89% - >99.99%Colore e forma:SolidPeso molecolare:379.37Anisomycin
CAS:Anisomycin (NSC-76712), an antibiotic from Streptomyces, blocks protein/DNA synthesis by targeting peptidyl transferase/80S ribosomes.Formula:C14H19NO4Purezza:98.33% - 99.81%Colore e forma:White Crystalline SolidPeso molecolare:265.3Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Formula:C18H20O5Purezza:99.33% - 99.86%Colore e forma:SolidPeso molecolare:316.35TOMATIDINE HYDROCHLORIDE
CAS:<p>Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway.</p>Formula:C27H46ClNO2Purezza:99.75% - ≥95%Colore e forma:SolidPeso molecolare:452.11Actein
CAS:Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.Formula:C37H56O11Purezza:≥98%Colore e forma:Brown PowderPeso molecolare:676.83Polyphyllin I
CAS:<p>Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,</p>Formula:C44H70O16Purezza:98% - 99.5%Colore e forma:SolidPeso molecolare:855.02Ro 31-8220 Mesylate
CAS:<p>Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.</p>Formula:C25H23N5O2S·CH4O3SPurezza:98.79% - 99.02%Colore e forma:SolidPeso molecolare:553.65Guggulsterone
CAS:<p>Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.</p>Formula:C21H28O2Purezza:99.4% - 99.8%Colore e forma:Light Yellow PowderPeso molecolare:312.45JNK-IN-7
CAS:JNK-IN-7 (JNK inhibitor) is a selective JNK1/2/3 inhibitor (IC50: 1.54/1.99/0.75 nM).Formula:C28H27N7O2Purezza:98.02% - 99.53%Colore e forma:SolidPeso molecolare:493.56CC-401 Hydrochloride
CAS:CC-401 Hydrochloride (CC401 HCl) is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with antineoplastic activity.Formula:C22H25ClN6OPurezza:99.71% - ≥95%Colore e forma:SolidPeso molecolare:424.93JIP-1 (153-163) acetate(438567-88-5 free base)
JNK peptide inhibitor. Mimics JIP-1 residues 153-163. Micromolar affinity, little effect on p38, ERK.Formula:C63H108N20O16Purezza:92.89%Colore e forma:SolidPeso molecolare:1401.65Ro 31-8220
CAS:Ro 31-8220: potent PKC inhibitor (IC50: 5-27 nM). Affects MAPKAP-K1b, MSK1, S6K1, GSK3β (IC50: 3-38 nM), not MKK3/4/6/7.Formula:C25H23N5O2SColore e forma:SolidPeso molecolare:457.55Bentamapimod
CAS:<p>Bentamapimod (AS 602801) is a novel, orally active inhibitor of JNK.</p>Formula:C25H23N5O2SPurezza:97.04% - 99.92%Colore e forma:SolidPeso molecolare:457.55Astragaloside IV
CAS:Astragaloside IV suppresses ERK1/2, JNK, MMP-2/9 in breast cancer; inhibits adenovirus and protects cardiovascular, immune, digestive, nervous systems.Formula:C41H68O14Purezza:99% - 99.84%Colore e forma:Hydroscopic Brown Or Yellow PowderPeso molecolare:784.97
