Ras
Le proteine Ras sono piccole GTPasi che agiscono come interruttori molecolari nella via di segnalazione MAPK, controllando la crescita, la differenziazione e la sopravvivenza cellulare. Ras attivato avvia una cascata di segnalazione che include Raf, MEK ed ERK, portando a varie risposte cellulari. Le mutazioni nei geni Ras sono comuni nei tumori, rendendo Ras un importante focus della ricerca sul cancro. Presso CymitQuimica, offriamo una gamma di modulatori di Ras per supportare la tua ricerca in biologia del cancro, trasduzione del segnale e sviluppo terapeutico.
Trovati 167 prodotti per "Ras".
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Phellodendrine chloride
CAS:Phellodendrine chloride combats kidney inflammation by blocking macrophage and T cell activity in glomeruli.Formula:C20H24ClNO4Purezza:98.85% - 99.05%Colore e forma:SolidPeso molecolare:377.86Ref: TM-T5S0777
5mg50,00€1mL*10mM (DMSO)58,00€10mg71,00€25mg101,00€50mg150,00€100mg215,00€200mg318,00€Y16
CAS:Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.Formula:C24H20N2O3Purezza:98.26% - 99.85%Colore e forma:SolidPeso molecolare:384.43Ref: TM-T3553
1mg34,00€2mg48,00€5mg70,00€1mL*10mM (DMSO)77,00€10mg109,00€25mg177,00€50mg263,00€100mg389,00€NSC 23766 trihydrochloride
CAS:NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs; no inhibitory for RhoA or Cdc42.Formula:C24H35N7·3HClPurezza:96.48% - 99.81%Colore e forma:SolidPeso molecolare:530.96CID-1067700
CAS:CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).Formula:C18H18N2O4S2Purezza:99.46%Colore e forma:SolidPeso molecolare:390.48Ref: TM-T7558
1mg34,00€2mg49,00€5mg71,00€1mL*10mM (DMSO)78,00€10mg105,00€25mg178,00€50mg234,00€100mg303,00€MLS-573151
CAS:MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Formula:C21H19N3O2SPurezza:98.80%Colore e forma:White SolidPeso molecolare:377.46Ref: TM-T22106
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg86,00€25mg161,00€50mg245,00€100mg363,00€200mg515,00€CCG-222740
CAS:CCG-222740 is an inhibitor of Rho/MRTF pathwayFormula:C23H19ClF2N2O3Purezza:98.76%Colore e forma:SolidPeso molecolare:444.86Ref: TM-T7764
2mg39,00€5mg62,00€1mL*10mM (DMSO)66,00€10mg94,00€25mg172,00€50mg260,00€100mg371,00€200mg530,00€Salirasib
CAS:Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.Formula:C22H30O2SPurezza:99.45%Colore e forma:SolidPeso molecolare:358.54Ref: TM-T6163
5mg34,00€1mL*10mM (DMSO)39,00€10mg50,00€25mg90,00€50mg150,00€100mg210,00€200mg344,00€500mg567,00€Kobe2602
CAS:Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.Formula:C14H9F4N5O4SPurezza:98.36% - 99.39%Colore e forma:SolidPeso molecolare:419.31Arglabin
CAS:Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.Formula:C15H18O3Purezza:98.97% - 99.62%Colore e forma:SolidPeso molecolare:246.3Ref: TM-TQ0165
1mg84,00€2mg123,00€5mg227,00€1mL*10mM (DMSO)251,00€10mg341,00€25mg492,00€50mg655,00€100mg982,00€200mg1.314,00€BQU57
CAS:BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.Formula:C16H13F3N4OPurezza:97.45% - 98.72%Colore e forma:SolidPeso molecolare:334.3Sotorasib
CAS:Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C.Formula:C30H30F2N6O3Purezza:98% - 99.95%Colore e forma:SolidPeso molecolare:560.594Ref: TM-T8684
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)93,00€10mg119,00€25mg213,00€50mg354,00€100mg434,00€500mg973,00€1g1.288,00€KRAS inhibitor-9
CAS:KRAS inhibitor-9 (DUN09716) hinders GTP-KRAS formation, with a Kd of 92 μM, causes G2/M arrest, and induces apoptosis in mutated NSC-LC cells.Formula:C13H9ClN2S2Purezza:99.66%Colore e forma:White SolidPeso molecolare:292.81Ref: TM-T8756
1mg57,00€2mg81,00€5mg113,00€1mL*10mM (DMSO)126,00€10mg178,00€25mg334,00€50mg485,00€100mg622,00€CID44216842
CAS:CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.Formula:C22H20BrN3O3SPurezza:99.66%Colore e forma:White SolidPeso molecolare:486.38Ref: TM-T8930
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg85,00€25mg159,00€50mg244,00€100mg359,00€200mg512,00€Eicosapentaenoic Acid
CAS:Eicosapentaenoic Acid is an ω-3 fatty acid and an inhibitor of fatty acid synthase (FASN). High-Quality, Low-Cost!Formula:C20H30O2Purezza:97.03% - 99.83%Colore e forma:Transparent LiquidPeso molecolare:302.45K-Ras-IN-1
CAS:K-Ras-IN-1 is a K-Ras inhibitor.Formula:C11H13NOSPurezza:98.72%Colore e forma:White SolidPeso molecolare:207.29MRTX1133
CAS:View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D.Formula:C33H31F3N6O2Purezza:97.39% - 99.6%Colore e forma:SolidPeso molecolare:600.63Ref: TM-T9303
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta1mg47,00€5mg100,00€1mL*10mM (DMSO)135,00€ML-098
CAS:ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).Formula:C19H19NO3Purezza:99.06% - 99.23%Colore e forma:SolidPeso molecolare:309.36Ref: TM-T4619
1mg37,00€2mg50,00€5mg66,00€1mL*10mM (DMSO)84,00€10mg94,00€25mg190,00€50mg268,00€100mg374,00€500mg884,00€Lonafarnib
CAS:Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).Formula:C27H31Br2ClN4O2Purezza:98% - 99.94%Colore e forma:White SolidPeso molecolare:638.82Oncrasin-1
CAS:Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrationsFormula:C16H12ClNOPurezza:99.75%Colore e forma:White SolidPeso molecolare:269.73Z62954982
CAS:Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteriesFormula:C20H21N3O5SPurezza:98.28%Colore e forma:SolidPeso molecolare:415.46Ref: TM-T37113
1mg35,00€5mg75,00€1mL*10mM (DMSO)87,00€10mg105,00€25mg173,00€50mg255,00€100mg371,00€200mg530,00€
